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The map label for this gene is murA

Identifier: 15836102

GI number: 15836102

Start: 660067

End: 661443

Strand: Reverse

Name: murA

Synonym: CPj0571

Alternate gene names: 15836102

Gene position: 661443-660067 (Counterclockwise)

Preceding gene: 15836104

Following gene: 15836096

Centisome position: 53.93

GC content: 45.17

Gene sequence:

>1377_bases
ATGCAGATTGCTCAAGTATTTGGTTGTGGTAGACTTAATGGTGAGGTAAAAGTTTCAGGAGCAAAAAATGCTGCAACTAA
GCTGCTTGTTGCTTCTTTACTTTCTGATCAGAAGTGCACACTGCGGAATGTCCCCGATATAGGAGATGTTTCCTTAACTG
TAGAGTTATGCAAGTCGCTAGGAGCACATGTTTCTTGGGATAAGGAAACAGAGGTTTTGGAAATCTATACTCCCGAAATA
CAATGCACAAGAGTTCCTCCCACATTTTCAAATGTCAATAGGATCCCCATCCTTTTATTAGGAGCGCTGTTAGGGCGTTG
CCCCGAAGGTGTCTATGTTCCCACTGTGGGGGGAGATGCTATAGGAGAAAGGACCTTAAACTTTCATTTTGAAGGGTTAA
AACAACTTGGTGTGCAGATTTCCTCTGATAGTTCGGGATACTACGCAAAGGCTCCTCGAGGTCTTAAAGGGAATTATATT
CATCTACCCTATCCTTCTGTAGGGGCTACAGAAAATCTCATACTCGCAGCAATTCATGCTAAAGGAAGAACGGTTATAAA
AAATGTAGCTCTCGAAGCTGAAATCTTAGATTTGGTGCTCTTTTTGCAAAAGGCAGGGGCGGATATCACTACCGATAATG
ATCGTACGATAGATATTTTTGGCACTGGAGGTCTCGGCTCTGTAGACCACACCATCCTTCCAGATAAGATTGAAGCAGCC
TCTTTTGGAATGGCCGCGGTTGTCTCTGGAGGACGTGTTTTCGTCCGAAATGCTAAACAAGAACTTCTGATTCCCTTCCT
CAAGATGTTGCGCTCCATAGGCGGAGGATTTTTGGTCTCCGAGTCGGGAATAGAATTTTTTCAAGAACGCCCCTTGGTGG
GAGGTGTTGTCTTGGAAACCGATGTTCATCCAGGGTTCCTGACGGACTGGCAACAACCCTTCGCAGTTCTACTATCACAG
GCTCAGGGATCTTCAGTAATCCATGAGACTGTCCATGAAAATCGCCTCGGCTACCTTCATGGTCTTCAGCACATGGGAGC
TGAGTGTCAGCTTTTTCATCAGTGCTTAAGTACCAAGGCATGTCGTTATGCTATCGGGAATTTTCCTCACAGCGCTGTGA
TTCATGGGGCGACGCCTTTATGGGCCTCGCATTTAGTCATTCCAGATTTACGAGCAGGATTTGCCTATGTCATGGCAGCA
CTGATTGCAGAAGGAGGAGGCTCTATTATTGAGAACACTCATCTTCTAGATCGTGGATATACAAATTGGGTAGGCAAGCT
CAGAAGCCTCGGAGCTAAAATTCAGATCTTTGATATGGAACAGGAAGAACTTACAACCTCTCCAAAGTCTTTAGCCCTAA
GAGATGCATCCCTGTAG

Upstream 100 bases:

>100_bases
ATTAAGGAACTTTGATCTAAGGAAAAAGTTTGAATGGCAATAAACCTTCGAGAAGGTTAACGTTTCTTTTAGTGATTTTG
ATGCCAAAGGGGAACGGAGA

Downstream 100 bases:

>100_bases
CCAAGACTTGTTCAGCTAGAGCACATAGAAACAGTCTAGACTTAGCATAAGGGGAGTCTTGGATATGGCTGTCACGGAAG
AACCCATTGAATTTATGGGT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQIAQVFGCGRLNGEVKVSGAKNAATKLLVASLLSDQKCTLRNVPDIGDVSLTVELCKSLGAHVSWDKETEVLEIYTPEI
QCTRVPPTFSNVNRIPILLLGALLGRCPEGVYVPTVGGDAIGERTLNFHFEGLKQLGVQISSDSSGYYAKAPRGLKGNYI
HLPYPSVGATENLILAAIHAKGRTVIKNVALEAEILDLVLFLQKAGADITTDNDRTIDIFGTGGLGSVDHTILPDKIEAA
SFGMAAVVSGGRVFVRNAKQELLIPFLKMLRSIGGGFLVSESGIEFFQERPLVGGVVLETDVHPGFLTDWQQPFAVLLSQ
AQGSSVIHETVHENRLGYLHGLQHMGAECQLFHQCLSTKACRYAIGNFPHSAVIHGATPLWASHLVIPDLRAGFAYVMAA
LIAEGGGSIIENTHLLDRGYTNWVGKLRSLGAKIQIFDMEQEELTTSPKSLALRDASL

Sequences:

>Translated_458_residues
MQIAQVFGCGRLNGEVKVSGAKNAATKLLVASLLSDQKCTLRNVPDIGDVSLTVELCKSLGAHVSWDKETEVLEIYTPEI
QCTRVPPTFSNVNRIPILLLGALLGRCPEGVYVPTVGGDAIGERTLNFHFEGLKQLGVQISSDSSGYYAKAPRGLKGNYI
HLPYPSVGATENLILAAIHAKGRTVIKNVALEAEILDLVLFLQKAGADITTDNDRTIDIFGTGGLGSVDHTILPDKIEAA
SFGMAAVVSGGRVFVRNAKQELLIPFLKMLRSIGGGFLVSESGIEFFQERPLVGGVVLETDVHPGFLTDWQQPFAVLLSQ
AQGSSVIHETVHENRLGYLHGLQHMGAECQLFHQCLSTKACRYAIGNFPHSAVIHGATPLWASHLVIPDLRAGFAYVMAA
LIAEGGGSIIENTHLLDRGYTNWVGKLRSLGAKIQIFDMEQEELTTSPKSLALRDASL
>Mature_458_residues
MQIAQVFGCGRLNGEVKVSGAKNAATKLLVASLLSDQKCTLRNVPDIGDVSLTVELCKSLGAHVSWDKETEVLEIYTPEI
QCTRVPPTFSNVNRIPILLLGALLGRCPEGVYVPTVGGDAIGERTLNFHFEGLKQLGVQISSDSSGYYAKAPRGLKGNYI
HLPYPSVGATENLILAAIHAKGRTVIKNVALEAEILDLVLFLQKAGADITTDNDRTIDIFGTGGLGSVDHTILPDKIEAA
SFGMAAVVSGGRVFVRNAKQELLIPFLKMLRSIGGGFLVSESGIEFFQERPLVGGVVLETDVHPGFLTDWQQPFAVLLSQ
AQGSSVIHETVHENRLGYLHGLQHMGAECQLFHQCLSTKACRYAIGNFPHSAVIHGATPLWASHLVIPDLRAGFAYVMAA
LIAEGGGSIIENTHLLDRGYTNWVGKLRSLGAKIQIFDMEQEELTTSPKSLALRDASL

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=436, Percent_Identity=34.6330275229358, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_CHLPN (Q9Z7Y2)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   D72063
- PIR:   G86561
- RefSeq:   NP_224767.1
- RefSeq:   NP_300626.1
- RefSeq:   NP_444729.1
- RefSeq:   NP_876865.1
- ProteinModelPortal:   Q9Z7Y2
- SMR:   Q9Z7Y2
- GeneID:   1467272
- GeneID:   895311
- GeneID:   919328
- GeneID:   963785
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0178
- KEGG:   cpn:CPn0571
- KEGG:   cpt:CpB0592
- TIGR:   CP_0178
- HOGENOM:   HBG482701
- OMA:   LVPKAMV
- ProtClustDB:   PRK09369
- BioCyc:   CPNE115711:CP_0178-MONOMER
- BioCyc:   CPNE115713:CPN0571-MONOMER
- BioCyc:   CPNE138677:CPJ0571-MONOMER
- BioCyc:   CPNE182082:CPB0592-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 49330; Mature: 49330

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIAQVFGCGRLNGEVKVSGAKNAATKLLVASLLSDQKCTLRNVPDIGDVSLTVELCKSL
CCCHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
GAHVSWDKETEVLEIYTPEIQCTRVPPTFSNVNRIPILLLGALLGRCPEGVYVPTVGGDA
CCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCH
IGERTLNFHFEGLKQLGVQISSDSSGYYAKAPRGLKGNYIHLPYPSVGATENLILAAIHA
HCCCEEEHHHHHHHHHCCEEECCCCCEEEECCCCCCCCEEECCCCCCCCCCCEEEEEEEC
KGRTVIKNVALEAEILDLVLFLQKAGADITTDNDRTIDIFGTGGLGSVDHTILPDKIEAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHH
SFGMAAVVSGGRVFVRNAKQELLIPFLKMLRSIGGGFLVSESGIEFFQERPLVGGVVLET
HCCHHEEECCCEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCCCEEEEE
DVHPGFLTDWQQPFAVLLSQAQGSSVIHETVHENRLGYLHGLQHMGAECQLFHQCLSTKA
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCHH
CRYAIGNFPHSAVIHGATPLWASHLVIPDLRAGFAYVMAALIAEGGGSIIENTHLLDRGY
HHHHHCCCCCCCEEECCCCHHHHCEECCCHHHHHHHHHHHHHHCCCCCCEECCCHHHCCH
TNWVGKLRSLGAKIQIFDMEQEELTTSPKSLALRDASL
HHHHHHHHHCCCEEEEEECCHHHHHCCCHHHEEECCCC
>Mature Secondary Structure
MQIAQVFGCGRLNGEVKVSGAKNAATKLLVASLLSDQKCTLRNVPDIGDVSLTVELCKSL
CCCHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
GAHVSWDKETEVLEIYTPEIQCTRVPPTFSNVNRIPILLLGALLGRCPEGVYVPTVGGDA
CCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCH
IGERTLNFHFEGLKQLGVQISSDSSGYYAKAPRGLKGNYIHLPYPSVGATENLILAAIHA
HCCCEEEHHHHHHHHHCCEEECCCCCEEEECCCCCCCCEEECCCCCCCCCCCEEEEEEEC
KGRTVIKNVALEAEILDLVLFLQKAGADITTDNDRTIDIFGTGGLGSVDHTILPDKIEAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHH
SFGMAAVVSGGRVFVRNAKQELLIPFLKMLRSIGGGFLVSESGIEFFQERPLVGGVVLET
HCCHHEEECCCEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCCCEEEEE
DVHPGFLTDWQQPFAVLLSQAQGSSVIHETVHENRLGYLHGLQHMGAECQLFHQCLSTKA
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCHH
CRYAIGNFPHSAVIHGATPLWASHLVIPDLRAGFAYVMAALIAEGGGSIIENTHLLDRGY
HHHHHCCCCCCCEEECCCCHHHHCEECCCHHHHHHHHHHHHHHCCCCCCEECCCHHHCCH
TNWVGKLRSLGAKIQIFDMEQEELTTSPKSLALRDASL
HHHHHHHHHCCCEEEEEECCHHHHHCCCHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362