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The map label for this gene is argS

Identifier: 15836101

GI number: 15836101

Start: 658428

End: 660113

Strand: Direct

Name: argS

Synonym: CPj0570

Alternate gene names: 15836101

Gene position: 658428-660113 (Clockwise)

Preceding gene: 15836100

Following gene: 15836103

Centisome position: 53.68

GC content: 41.22

Gene sequence:

>1686_bases
ATGTCGACATTACTTTCTATCTTATCTGTGATATGTTCTCAGGCAATAGCAAAGGCATTTCCTAATCTAGAAGATTGGGC
TCCAGAAATTACCCCGTCTACAAAAGAACATTTTGGCCATTATCAATGTAACGATGCGATGAAATTGGCTCGTGTTTTAA
AAAAAGCTCCGAGGGCTATTGCTGAGGCCATAGTAGCTGAGCTTCCTCAAGAGCCTTTTTCTTTAATTGAAATTGCTGGA
GCAGGATTTATAAACTTTACCTTCTCTCCAGTATTTCTAAATCAACAGCTAGAACATTTCAAGGACGCTCTAAAATTAGG
ATTTCAAGTTTCCCAACCTAAAAAAATTATCATTGATTTTTCCTCTCCAAATATTGCTAAAGACATGCATGTTGGGCATT
TACGCTCTACAATTATTGGGGATAGCCTTGCTAGGATCTTCTCCTATGTAGGTCATGATGTACTTAGACTCAATCATATC
GGAGATTGGGGAACTGCATTTGGGATGTTGATCACCTATTTGCAAGAAAATCCCTGTGACTATAGTGATCTTGAGGATCT
TACGAGTCTTTATAAGAAGGCCTATGTCTGCTTTACTAATGACGAAGAGTTTAAAAAACGCTCCCAACAGAATGTGGTAG
CATTACAGGCTAAGGATCCGCAAGCCATTGCTATTTGGGAGAAGATCTGTGAGACTTCGGAAAAAGCCTTCCAGAAAATC
TATGATATTTTGGACATCGTGGTTGAAAAACGCGGAGAATCTTTCTATAACCCTTTCCTTCCTGAAATTATCGAAGATCT
AGAGAAGAAAGGCCTTCTCACTGTTTCCAACGATGCTAAATGTGTATTTCATGAAGCCTTTTCGATTCCTTTTATGGTTC
AAAAAAGTGATGGGGGCTACAACTACGCCACCACAGATCTTGCTGCGATGCGCTATCGCATAGAGGAAGATCATGCCGAT
AAGATCATCATTGTTACTGACTTAGGTCAGTCTCTACATTTCCAACTCCTTGAGGCTACAGCAATTGCTGCGGGCTATCT
ACAACCTGGAATATTTTCTCATGTAGGCTTTGGCCTTGTCTTAGATCCTCAAGGGAAGAAACTTAAAACCCGCTCTGGAG
AAAACGTAAAGCTCCGAGAGCTTCTAGATACTGCTATTGAAAAAGCTGAAGAAGCATTGCGAGAACATCGACCCGAACTT
ACGGATGAGGCAATCCAAGAAAGAGCTCCCGTCATTGGAATCAACGCTATAAAATACAGTGATCTCTCTTCCCATCGCAC
TAGCGACTATGTCTTTTCTTTTGAAAAGATGCTCCGCTTCGAAGGAAACACCGCCATGTTTCTACTGTATGCCTACGTGC
GAATCCAAGGAATTAAACGTCGTTTAGGAATTTCTCAGCTGTCATTAGAGGGACCTCCGGAGATTCAAGAACCTGCTGAA
GAGTTGCTTGCATTAACTTTGCTACGCTTCCCCGAAGCTTTAGAGAGCACAATTAAAGAGTTGTGTCCTCATTTTCTTAC
AGATTATCTTTATAATCTCACCCATAAATTCAATGGGTTCTTCCGTGACAGCCATATCCAAGACTCCCCTTATGCTAAGT
CTAGACTGTTTCTATGTGCTCTAGCTGAACAAGTCTTGGCTACAGGGATGCATCTCTTAGGGCTAAAGACTTTGGAGAGG
TTGTAA

Upstream 100 bases:

>100_bases
AAAGAAACCTATCAGATCATCACGAATCAAACTATGAACAAAATTGCCGAGCTCAAAGCATGGTATGAATCGGGGTGCAA
AGGAGACGTCCCCTAAACTT

Downstream 100 bases:

>100_bases
GTTCTTCCTGTTCCATATCAAAGATCTGAATTTTAGCTCCGAGGCTTCTGAGCTTGCCTACCCAATTTGTATATCCACGA
TCTAGAAGATGAGTGTTCTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MSTLLSILSVICSQAIAKAFPNLEDWAPEITPSTKEHFGHYQCNDAMKLARVLKKAPRAIAEAIVAELPQEPFSLIEIAG
AGFINFTFSPVFLNQQLEHFKDALKLGFQVSQPKKIIIDFSSPNIAKDMHVGHLRSTIIGDSLARIFSYVGHDVLRLNHI
GDWGTAFGMLITYLQENPCDYSDLEDLTSLYKKAYVCFTNDEEFKKRSQQNVVALQAKDPQAIAIWEKICETSEKAFQKI
YDILDIVVEKRGESFYNPFLPEIIEDLEKKGLLTVSNDAKCVFHEAFSIPFMVQKSDGGYNYATTDLAAMRYRIEEDHAD
KIIIVTDLGQSLHFQLLEATAIAAGYLQPGIFSHVGFGLVLDPQGKKLKTRSGENVKLRELLDTAIEKAEEALREHRPEL
TDEAIQERAPVIGINAIKYSDLSSHRTSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLGISQLSLEGPPEIQEPAE
ELLALTLLRFPEALESTIKELCPHFLTDYLYNLTHKFNGFFRDSHIQDSPYAKSRLFLCALAEQVLATGMHLLGLKTLER
L

Sequences:

>Translated_561_residues
MSTLLSILSVICSQAIAKAFPNLEDWAPEITPSTKEHFGHYQCNDAMKLARVLKKAPRAIAEAIVAELPQEPFSLIEIAG
AGFINFTFSPVFLNQQLEHFKDALKLGFQVSQPKKIIIDFSSPNIAKDMHVGHLRSTIIGDSLARIFSYVGHDVLRLNHI
GDWGTAFGMLITYLQENPCDYSDLEDLTSLYKKAYVCFTNDEEFKKRSQQNVVALQAKDPQAIAIWEKICETSEKAFQKI
YDILDIVVEKRGESFYNPFLPEIIEDLEKKGLLTVSNDAKCVFHEAFSIPFMVQKSDGGYNYATTDLAAMRYRIEEDHAD
KIIIVTDLGQSLHFQLLEATAIAAGYLQPGIFSHVGFGLVLDPQGKKLKTRSGENVKLRELLDTAIEKAEEALREHRPEL
TDEAIQERAPVIGINAIKYSDLSSHRTSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLGISQLSLEGPPEIQEPAE
ELLALTLLRFPEALESTIKELCPHFLTDYLYNLTHKFNGFFRDSHIQDSPYAKSRLFLCALAEQVLATGMHLLGLKTLER
L
>Mature_560_residues
STLLSILSVICSQAIAKAFPNLEDWAPEITPSTKEHFGHYQCNDAMKLARVLKKAPRAIAEAIVAELPQEPFSLIEIAGA
GFINFTFSPVFLNQQLEHFKDALKLGFQVSQPKKIIIDFSSPNIAKDMHVGHLRSTIIGDSLARIFSYVGHDVLRLNHIG
DWGTAFGMLITYLQENPCDYSDLEDLTSLYKKAYVCFTNDEEFKKRSQQNVVALQAKDPQAIAIWEKICETSEKAFQKIY
DILDIVVEKRGESFYNPFLPEIIEDLEKKGLLTVSNDAKCVFHEAFSIPFMVQKSDGGYNYATTDLAAMRYRIEEDHADK
IIIVTDLGQSLHFQLLEATAIAAGYLQPGIFSHVGFGLVLDPQGKKLKTRSGENVKLRELLDTAIEKAEEALREHRPELT
DEAIQERAPVIGINAIKYSDLSSHRTSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLGISQLSLEGPPEIQEPAEE
LLALTLLRFPEALESTIKELCPHFLTDYLYNLTHKFNGFFRDSHIQDSPYAKSRLFLCALAEQVLATGMHLLGLKTLERL

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=591, Percent_Identity=42.1319796954315, Blast_Score=444, Evalue=1e-124,
Organism=Homo sapiens, GI197100773, Length=459, Percent_Identity=33.5511982570806, Blast_Score=223, Evalue=3e-58,
Organism=Escherichia coli, GI1788184, Length=578, Percent_Identity=39.9653979238754, Blast_Score=407, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI71985061, Length=594, Percent_Identity=38.7205387205387, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71985068, Length=569, Percent_Identity=39.3673110720562, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17532153, Length=501, Percent_Identity=26.3473053892216, Blast_Score=146, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320548, Length=547, Percent_Identity=31.2614259597806, Blast_Score=213, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6321883, Length=471, Percent_Identity=28.8747346072187, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI18859963, Length=601, Percent_Identity=41.0981697171381, Blast_Score=403, Evalue=1e-112,
Organism=Drosophila melanogaster, GI28571570, Length=519, Percent_Identity=27.9383429672447, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_CHLPN (Q9Z7Y3)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C72063
- PIR:   F86561
- RefSeq:   NP_224766.1
- RefSeq:   NP_300625.1
- RefSeq:   NP_444730.1
- RefSeq:   NP_876864.1
- ProteinModelPortal:   Q9Z7Y3
- SMR:   Q9Z7Y3
- GeneID:   1467271
- GeneID:   895322
- GeneID:   919329
- GeneID:   963786
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0179
- KEGG:   cpn:CPn0570
- KEGG:   cpt:CpB0593
- TIGR:   CP_0179
- HOGENOM:   HBG695395
- OMA:   LLPNVLC
- PhylomeDB:   Q9Z7Y3
- ProtClustDB:   PRK01611
- BioCyc:   CPNE115711:CP_0179-MONOMER
- BioCyc:   CPNE115713:CPN0570-MONOMER
- BioCyc:   CPNE138677:CPJ0570-MONOMER
- BioCyc:   CPNE182082:CPB0593-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63370; Mature: 63238

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLLSILSVICSQAIAKAFPNLEDWAPEITPSTKEHFGHYQCNDAMKLARVLKKAPRAI
CHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHH
AEAIVAELPQEPFSLIEIAGAGFINFTFSPVFLNQQLEHFKDALKLGFQVSQPKKIIIDF
HHHHHHHCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
SSPNIAKDMHVGHLRSTIIGDSLARIFSYVGHDVLRLNHIGDWGTAFGMLITYLQENPCD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHCCCCC
YSDLEDLTSLYKKAYVCFTNDEEFKKRSQQNVVALQAKDPQAIAIWEKICETSEKAFQKI
CCCHHHHHHHHHHEEEEECCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
YDILDIVVEKRGESFYNPFLPEIIEDLEKKGLLTVSNDAKCVFHEAFSIPFMVQKSDGGY
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEECCCCCEEEHHHCCCCEEEEECCCCC
NYATTDLAAMRYRIEEDHADKIIIVTDLGQSLHFQLLEATAIAAGYLQPGIFSHVGFGLV
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCEE
LDPQGKKLKTRSGENVKLRELLDTAIEKAEEALREHRPELTDEAIQERAPVIGINAIKYS
ECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEEEEEC
DLSSHRTSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLGISQLSLEGPPEIQEPAE
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHH
ELLALTLLRFPEALESTIKELCPHFLTDYLYNLTHKFNGFFRDSHIQDSPYAKSRLFLCA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LAEQVLATGMHLLGLKTLERL
HHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
STLLSILSVICSQAIAKAFPNLEDWAPEITPSTKEHFGHYQCNDAMKLARVLKKAPRAI
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHH
AEAIVAELPQEPFSLIEIAGAGFINFTFSPVFLNQQLEHFKDALKLGFQVSQPKKIIIDF
HHHHHHHCCCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
SSPNIAKDMHVGHLRSTIIGDSLARIFSYVGHDVLRLNHIGDWGTAFGMLITYLQENPCD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHCCCCC
YSDLEDLTSLYKKAYVCFTNDEEFKKRSQQNVVALQAKDPQAIAIWEKICETSEKAFQKI
CCCHHHHHHHHHHEEEEECCCHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
YDILDIVVEKRGESFYNPFLPEIIEDLEKKGLLTVSNDAKCVFHEAFSIPFMVQKSDGGY
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEECCCCCEEEHHHCCCCEEEEECCCCC
NYATTDLAAMRYRIEEDHADKIIIVTDLGQSLHFQLLEATAIAAGYLQPGIFSHVGFGLV
CCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCEE
LDPQGKKLKTRSGENVKLRELLDTAIEKAEEALREHRPELTDEAIQERAPVIGINAIKYS
ECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEEEEEC
DLSSHRTSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLGISQLSLEGPPEIQEPAE
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHH
ELLALTLLRFPEALESTIKELCPHFLTDYLYNLTHKFNGFFRDSHIQDSPYAKSRLFLCA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LAEQVLATGMHLLGLKTLERL
HHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362