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The map label for this gene is cdsA

Identifier: 15836098

GI number: 15836098

Start: 656215

End: 657141

Strand: Direct

Name: cdsA

Synonym: CPj0567

Alternate gene names: 15836098

Gene position: 656215-657141 (Clockwise)

Preceding gene: 15836097

Following gene: 15836099

Centisome position: 53.5

GC content: 40.02

Gene sequence:

>927_bases
GTGCTTAATTCAAATAAGTTTAAATCGAAGACCGGTGCATACGGTGATTTATTTCAGCGTGTTGTTGTTCATTCGTTAGT
ACTTACATTTTTGGTTCTTCTTCTCTATAGTTCCCTATTTCCCTTAACTTCTTTTGCTCTAGGGTTTATTACCGCGACTT
GTGGCGCTGTAGGAACTTATGAGTACTCCTCAATGGCGAAAGCCAAGATGCACTATCCATTAAGCACGTTTAGTGCGATC
GGATCTTTTTTATTTTTAGCATTAAGTTTTCTTTCCATTCGTTGGGGACACAGTCTCCCAGGATTCTTCGATGCTCTTCC
TTGGACCTTGCTTATTGTTTGGGTCGTGTGGAGTATCTTTAGAGTTCGAAAATCTACAATCGGCGCTTTACAGCTATCAG
GAGTCACTCTCTTTTCTATTTTGTATGTAGGGATTCCGATACGTTTATTCTTACATGTCCTTTATAGCTTTATTCATACC
CAAGAACCCTATCTTGGAATTTGGTGGGCTTCTTTTCTTATTGCCACAACTAAAGGTGCGGATATCTTCGGTTATTTCTT
CGGTAAAGCCTTTGGGAATAAGAAAATCGCCCCACAAATTAGCCCTAACAAAACTGTTGTAGGTTTTGTTGCAGGGTGTT
TGGGAGCCACGCTCATTAGTTTTATTTTCTTTCTACAGATTCCCACGAGGTTTGCGAGTTACTTCCCGATGCCTGCGATT
TTAATTCCTTTAGGTCTTGCTTTAGGAATCACAGGATTTTTTGGAGATATTATTGAATCCATATTTAAGCGTGATGCTCA
TTTGAAAAATAGCAACAAGCTCAAGGCTGTGGGTGGTATGCTGGATACCTTAGACTCACTGCTCCTGTCCACGCCGATTG
CTTACTTATTTTTGCTCATAACCCAATCTAAAGAGTTTATTGGATGA

Upstream 100 bases:

>100_bases
ACTATATATCACGGATACCTTGTGGCCAGATTTTACGCCTCAAGATTTGTTTGAAGCGATTAACGTATACCAGCAAAGAT
CAAGACGAGGGGGGAAATAG

Downstream 100 bases:

>100_bases
TTATCACTATTGATGGGCCTTCAGGAACAGGAAAAAGCACAACAGCGAAAGCTTTAGCCGACCATCTTCATTTCAATTAC
TGTAATACAGGGAAGATGTA

Product: phosphatidate cytidylytransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MLNSNKFKSKTGAYGDLFQRVVVHSLVLTFLVLLLYSSLFPLTSFALGFITATCGAVGTYEYSSMAKAKMHYPLSTFSAI
GSFLFLALSFLSIRWGHSLPGFFDALPWTLLIVWVVWSIFRVRKSTIGALQLSGVTLFSILYVGIPIRLFLHVLYSFIHT
QEPYLGIWWASFLIATTKGADIFGYFFGKAFGNKKIAPQISPNKTVVGFVAGCLGATLISFIFFLQIPTRFASYFPMPAI
LIPLGLALGITGFFGDIIESIFKRDAHLKNSNKLKAVGGMLDTLDSLLLSTPIAYLFLLITQSKEFIG

Sequences:

>Translated_308_residues
MLNSNKFKSKTGAYGDLFQRVVVHSLVLTFLVLLLYSSLFPLTSFALGFITATCGAVGTYEYSSMAKAKMHYPLSTFSAI
GSFLFLALSFLSIRWGHSLPGFFDALPWTLLIVWVVWSIFRVRKSTIGALQLSGVTLFSILYVGIPIRLFLHVLYSFIHT
QEPYLGIWWASFLIATTKGADIFGYFFGKAFGNKKIAPQISPNKTVVGFVAGCLGATLISFIFFLQIPTRFASYFPMPAI
LIPLGLALGITGFFGDIIESIFKRDAHLKNSNKLKAVGGMLDTLDSLLLSTPIAYLFLLITQSKEFIG
>Mature_308_residues
MLNSNKFKSKTGAYGDLFQRVVVHSLVLTFLVLLLYSSLFPLTSFALGFITATCGAVGTYEYSSMAKAKMHYPLSTFSAI
GSFLFLALSFLSIRWGHSLPGFFDALPWTLLIVWVVWSIFRVRKSTIGALQLSGVTLFSILYVGIPIRLFLHVLYSFIHT
QEPYLGIWWASFLIATTKGADIFGYFFGKAFGNKKIAPQISPNKTVVGFVAGCLGATLISFIFFLQIPTRFASYFPMPAI
LIPLGLALGITGFFGDIIESIFKRDAHLKNSNKLKAVGGMLDTLDSLLLSTPIAYLFLLITQSKEFIG

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family

Homologues:

Organism=Escherichia coli, GI87081696, Length=152, Percent_Identity=34.2105263157895, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787677, Length=123, Percent_Identity=36.5853658536585, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDSA_CHLPN (Q9Z7Y6)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C86561
- PIR:   H72062
- RefSeq:   NP_224763.1
- RefSeq:   NP_300622.1
- RefSeq:   NP_444733.1
- RefSeq:   NP_876861.1
- GeneID:   1467268
- GeneID:   895339
- GeneID:   919325
- GeneID:   962984
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0182
- KEGG:   cpn:CPn0567
- KEGG:   cpt:CpB0589
- TIGR:   CP_0182
- HOGENOM:   HBG414084
- OMA:   ESIFKRD
- ProtClustDB:   CLSK871390
- BioCyc:   CPNE115711:CP_0182-MONOMER
- BioCyc:   CPNE115713:CPN0567-MONOMER
- BioCyc:   CPNE138677:CPJ0567-MONOMER
- BioCyc:   CPNE182082:CPB0589-MONOMER
- BRENDA:   2.7.7.41
- InterPro:   IPR000374

Pfam domain/function: PF01148 CTP_transf_1

EC number: =2.7.7.41

Molecular weight: Translated: 34032; Mature: 34032

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcd41d4c)-; HASH(0xcd6ea44)-; HASH(0xc100678)-; HASH(0xd13b6e8)-; HASH(0xcdd52a0)-; HASH(0xc735bfc)-; HASH(0xcfc2fc8)-; HASH(0xc1d48b4)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCH
>Mature Secondary Structure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HHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362