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Identifier: 15836074

GI number: 15836074

Start: 628045

End: 628926

Strand: Direct

Name: Not Available

Synonym: CPj0543

Alternate gene names: 15836074

Gene position: 628045-628926 (Clockwise)

Preceding gene: 15836073

Following gene: 15836078

Centisome position: 51.2

GC content: 41.84

Gene sequence:

>882_bases
ATGCTCTCCTCACTAATCCGTGATTCATTTCCCCTTCTTATTTTACTTCCCACATTCCTAGCGGCATTAGGAGCCTCCGT
AGCTGGCGGCGTTATGGGAACCTATATCGTTGTAAAACGTATTGTTTCAATTAGTGGAAGTATATCTCATGCAATTCTAG
GAGGAATTGGCCTCACCCTATGGATACAATATAAGCTTCATCTCTCTTTTTTCCCTATGTATGGAGCTATTGTAGGAGCT
ATTTTTCTAGCTCTTTGCATCGGCAAGATCCACCTGAAATACCAAGAAAGGGAAGACTCTTTGATTGCGATGATTTGGTC
TGTGGGCATGGCAATTGGAATTATATTCATTTCCAGGCTTCCCACCTTTAATGGAGAGCTCATCAATTTTCTATTTGGGA
ACATTCTCTGGGTCACCCCTTCAGACCTCTATAGCTTAGGAATCTTTGATCTTCTTGTTTTAGGAATTGTGGTCCTTTGC
CACACCCGGTTCCTTGCTCTTTGCTTTGATGAGAGGTACACGGCTTTAAACCATTGTTCTGTACAGCTGTGGTATTTCCT
ACTTCTTGTTCTGACAGCAATCACGATTGTGATGTTGATTTATGTGATGGGAACGATTCTGATGCTTAGCATGCTCGTCT
TACCTGTTGCTATAGCGTGTAGATTTTCGTACAAGATGACACGAATTATGTTCATCTCGGTCCTCTTGAATATCTTATGT
TCTTTTTCTGGAATTTGCATCGCCTACTGTTTAGATTTCCCAGTAGGTCCTACGATATCATTGCTGATGGGGTTAGGTTA
TACAGCGAGTCTTTGTGTGAAGAAGCGGTACAATCCGTCGACGCCTTCTCCTGTAAGTCCTGAAATCAATACAAATGTAT
AG

Upstream 100 bases:

>100_bases
ATAAAGTTTTTTATATGAACAAAACTTTGACTTCATTGGCAGACACTTCGACCTTAACAGACCAATTTTGTTGTCATCCC
TATAAAAATCAGGAATTTTC

Downstream 100 bases:

>100_bases
CTAGGGAAGCGCTTTTGGAAGCTTTGGAGGCATTCTTCCTGTTCGTCAGGAAGAAGATCATCAATTTTATTTAAAGCTAC
CAGCATATCTTTCTTTTCAA

Product: metal transport protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MLSSLIRDSFPLLILLPTFLAALGASVAGGVMGTYIVVKRIVSISGSISHAILGGIGLTLWIQYKLHLSFFPMYGAIVGA
IFLALCIGKIHLKYQEREDSLIAMIWSVGMAIGIIFISRLPTFNGELINFLFGNILWVTPSDLYSLGIFDLLVLGIVVLC
HTRFLALCFDERYTALNHCSVQLWYFLLLVLTAITIVMLIYVMGTILMLSMLVLPVAIACRFSYKMTRIMFISVLLNILC
SFSGICIAYCLDFPVGPTISLLMGLGYTASLCVKKRYNPSTPSPVSPEINTNV

Sequences:

>Translated_293_residues
MLSSLIRDSFPLLILLPTFLAALGASVAGGVMGTYIVVKRIVSISGSISHAILGGIGLTLWIQYKLHLSFFPMYGAIVGA
IFLALCIGKIHLKYQEREDSLIAMIWSVGMAIGIIFISRLPTFNGELINFLFGNILWVTPSDLYSLGIFDLLVLGIVVLC
HTRFLALCFDERYTALNHCSVQLWYFLLLVLTAITIVMLIYVMGTILMLSMLVLPVAIACRFSYKMTRIMFISVLLNILC
SFSGICIAYCLDFPVGPTISLLMGLGYTASLCVKKRYNPSTPSPVSPEINTNV
>Mature_293_residues
MLSSLIRDSFPLLILLPTFLAALGASVAGGVMGTYIVVKRIVSISGSISHAILGGIGLTLWIQYKLHLSFFPMYGAIVGA
IFLALCIGKIHLKYQEREDSLIAMIWSVGMAIGIIFISRLPTFNGELINFLFGNILWVTPSDLYSLGIFDLLVLGIVVLC
HTRFLALCFDERYTALNHCSVQLWYFLLLVLTAITIVMLIYVMGTILMLSMLVLPVAIACRFSYKMTRIMFISVLLNILC
SFSGICIAYCLDFPVGPTISLLMGLGYTASLCVKKRYNPSTPSPVSPEINTNV

Specific function: Part of an ATP-driven transport system CPn_0541/CPn_0542/CPn_0543 for a metal

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family

Homologues:

Organism=Escherichia coli, GI1788166, Length=262, Percent_Identity=25.1908396946565, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y543_CHLPN (Q9Z809)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C86558
- PIR:   H72064
- RefSeq:   NP_224739.1
- RefSeq:   NP_300598.1
- RefSeq:   NP_444760.1
- RefSeq:   NP_876836.1
- ProteinModelPortal:   Q9Z809
- GeneID:   1467243
- GeneID:   895265
- GeneID:   919287
- GeneID:   962943
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0209
- KEGG:   cpj:CPj0543
- KEGG:   cpn:CPn0543
- KEGG:   cpt:CpB0565
- TIGR:   CP_0209
- HOGENOM:   HBG733179
- OMA:   ISHAVFG
- PhylomeDB:   Q9Z809
- ProtClustDB:   CLSK871369
- BioCyc:   CPNE115711:CP_0209-MONOMER
- BioCyc:   CPNE115713:CPN0543-MONOMER
- BioCyc:   CPNE138677:CPJ0543-MONOMER
- BioCyc:   CPNE182082:CPB0565-MONOMER
- InterPro:   IPR001626

Pfam domain/function: PF00950 ABC-3

EC number: NA

Molecular weight: Translated: 32244; Mature: 32244

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc0b6d30)-; HASH(0xcccaef8)-; HASH(0xcfdcd74)-; HASH(0xc7d4864)-; HASH(0xcba08bc)-; HASH(0xbfa643c)-; HASH(0xc4fcc2c)-;

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSLIRDSFPLLILLPTFLAALGASVAGGVMGTYIVVKRIVSISGSISHAILGGIGLTL
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
WIQYKLHLSFFPMYGAIVGAIFLALCIGKIHLKYQEREDSLIAMIWSVGMAIGIIFISRL
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTFNGELINFLFGNILWVTPSDLYSLGIFDLLVLGIVVLCHTRFLALCFDERYTALNHCS
CCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQLWYFLLLVLTAITIVMLIYVMGTILMLSMLVLPVAIACRFSYKMTRIMFISVLLNILC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFSGICIAYCLDFPVGPTISLLMGLGYTASLCVKKRYNPSTPSPVSPEINTNV
HHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MLSSLIRDSFPLLILLPTFLAALGASVAGGVMGTYIVVKRIVSISGSISHAILGGIGLTL
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
WIQYKLHLSFFPMYGAIVGAIFLALCIGKIHLKYQEREDSLIAMIWSVGMAIGIIFISRL
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTFNGELINFLFGNILWVTPSDLYSLGIFDLLVLGIVVLCHTRFLALCFDERYTALNHCS
CCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQLWYFLLLVLTAITIVMLIYVMGTILMLSMLVLPVAIACRFSYKMTRIMFISVLLNILC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFSGICIAYCLDFPVGPTISLLMGLGYTASLCVKKRYNPSTPSPVSPEINTNV
HHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362