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The map label for this gene is gseA

Identifier: 15835689

GI number: 15835689

Start: 197603

End: 198916

Strand: Direct

Name: gseA

Synonym: CPj0154

Alternate gene names: 15835689

Gene position: 197603-198916 (Clockwise)

Preceding gene: 15835688

Following gene: 15835698

Centisome position: 16.11

GC content: 39.73

Gene sequence:

>1314_bases
ATGATGCTACGAGGTGTCCATCGTATTTTTAAGTGTTTCTACGATGTTGTTTTAGTTTGTGCATTTGTAATTGCCTTACC
TAAGCTTCTTTATAAGATGTTAGTTTATGGTAAGTATAAGAAATCTCTAGCAGTTCGTTTTGGTCTGAAAAAGCCGCATG
TCCCTGGAGAAGGGCCTTTGGTGTGGTTTCATGGAGCATCTGTAGGGGAAGTTCGTTTGCTTCTACCTGTACTTGAAAAA
TTTTGTGAAGAATTTCCAGGTTGGCGTTGTCTAGTGACTTCATGTACAGAACTTGGAGTGCAGGTGGCAAGCCAAGTGTT
TATTCCTATGGGAGCCACTGTTTCAATACTGCCTTTGGATTTTAGCATAATTATCAAATCGGTAGTCGCTAAACTGCGTC
CCTCCCTTGCAGTCTTTTCTGAAGGGGACTGCTGGCTAAATTTTATTGAGGAAGCAAAACGTATAGGAGCAACTACTCTC
GTCATTAATGGTAGAATTTCCATAGATTCTTCAAAGCGTTTTAAATTTTTAAAGCGCCTAGGTAAAAACTATTTCTCTCC
AGTAGATGGATTTTTATTACAGGACGAAGTCCAAAAACAGCGTTTTCTTTCTTTAGGGATACCTGAACATAAATTGCAGG
TTACAGGGAATATTAAGACCTATGTAGCAGCACAGACAGCACTGCACTTAGAAAGGGAAACTTGGAGAGATCGTTTGAGA
TTGCCAACGGACTCGAAATTAGTAATCCTAGGTTCTATGCATAGAAGTGATGCAGGAAAATGGCTTCCTGTAGTGCAGAA
ATTAATAAAAGAGGGGGTCTCAGTTTTATGGGTGCCAAGACACGTTGAAAAGACCAAGGATGTTGAAGAATCTTTGCATC
GGTTGCACATTCCTTATGGGTTGTGGAGCCGCGGCGCCAATTTTTCTTATGTACCAGTTGTCGTTGTTGATGAAATTGGC
TTATTGAAACAACTTTATGTTGCTGGTGATTTAGCATTTGTTGGAGGTACTTTCGATCCTAAGATCGGAGGACATAATTT
ATTAGAACCTCTCCAATGTGAAGTCCCTTTAATTTTTGGTCCACATATTACATCGCAATCAGAGCTTGCGCAACGCCTGT
TGCTTTCTGGTGCAGGACTTTGTTTAGACGAAATAGAGCCTATAATCGATACAGTTTCTTTCTTACTAAATAATCAAGAA
GTGCGTGAGGCTTATGTACAGAAGGGAAAAGTGTTCGTAAAAGCAGAAACAGCTTCCTTTGACCGTACATGGAGAGCATT
AAAAAGTTATATTCCCTTGTACAAAAATAGTTAA

Upstream 100 bases:

>100_bases
AAGTTTTATCTTTGTCTCGAAGTGTAGTTGCAAAGTATCTAGAGAACGCTCAAATACGAAAAGAAATTTATGTTCCTAAT
AAACTAGTGAATTTTGTCCT

Downstream 100 bases:

>100_bases
GTTTGATAAATTCATCGGCATATCGCGGGATAGAGTAGTGGTCATCTCGTTGGGCTCATAACCCAAAGGTCGGAGGTTCG
AATCCTTCTCCCGCTAATTA

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MMLRGVHRIFKCFYDVVLVCAFVIALPKLLYKMLVYGKYKKSLAVRFGLKKPHVPGEGPLVWFHGASVGEVRLLLPVLEK
FCEEFPGWRCLVTSCTELGVQVASQVFIPMGATVSILPLDFSIIIKSVVAKLRPSLAVFSEGDCWLNFIEEAKRIGATTL
VINGRISIDSSKRFKFLKRLGKNYFSPVDGFLLQDEVQKQRFLSLGIPEHKLQVTGNIKTYVAAQTALHLERETWRDRLR
LPTDSKLVILGSMHRSDAGKWLPVVQKLIKEGVSVLWVPRHVEKTKDVEESLHRLHIPYGLWSRGANFSYVPVVVVDEIG
LLKQLYVAGDLAFVGGTFDPKIGGHNLLEPLQCEVPLIFGPHITSQSELAQRLLLSGAGLCLDEIEPIIDTVSFLLNNQE
VREAYVQKGKVFVKAETASFDRTWRALKSYIPLYKNS

Sequences:

>Translated_437_residues
MMLRGVHRIFKCFYDVVLVCAFVIALPKLLYKMLVYGKYKKSLAVRFGLKKPHVPGEGPLVWFHGASVGEVRLLLPVLEK
FCEEFPGWRCLVTSCTELGVQVASQVFIPMGATVSILPLDFSIIIKSVVAKLRPSLAVFSEGDCWLNFIEEAKRIGATTL
VINGRISIDSSKRFKFLKRLGKNYFSPVDGFLLQDEVQKQRFLSLGIPEHKLQVTGNIKTYVAAQTALHLERETWRDRLR
LPTDSKLVILGSMHRSDAGKWLPVVQKLIKEGVSVLWVPRHVEKTKDVEESLHRLHIPYGLWSRGANFSYVPVVVVDEIG
LLKQLYVAGDLAFVGGTFDPKIGGHNLLEPLQCEVPLIFGPHITSQSELAQRLLLSGAGLCLDEIEPIIDTVSFLLNNQE
VREAYVQKGKVFVKAETASFDRTWRALKSYIPLYKNS
>Mature_437_residues
MMLRGVHRIFKCFYDVVLVCAFVIALPKLLYKMLVYGKYKKSLAVRFGLKKPHVPGEGPLVWFHGASVGEVRLLLPVLEK
FCEEFPGWRCLVTSCTELGVQVASQVFIPMGATVSILPLDFSIIIKSVVAKLRPSLAVFSEGDCWLNFIEEAKRIGATTL
VINGRISIDSSKRFKFLKRLGKNYFSPVDGFLLQDEVQKQRFLSLGIPEHKLQVTGNIKTYVAAQTALHLERETWRDRLR
LPTDSKLVILGSMHRSDAGKWLPVVQKLIKEGVSVLWVPRHVEKTKDVEESLHRLHIPYGLWSRGANFSYVPVVVVDEIG
LLKQLYVAGDLAFVGGTFDPKIGGHNLLEPLQCEVPLIFGPHITSQSELAQRLLLSGAGLCLDEIEPIIDTVSFLLNNQE
VREAYVQKGKVFVKAETASFDRTWRALKSYIPLYKNS

Specific function: Transfers three 3-deoxy-D-mono octulonic acid (KDO) individually from CMP-KDO to a tetraacyldisaccharide 1,4'- bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=400, Percent_Identity=25, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 49159; Mature: 49159

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLRGVHRIFKCFYDVVLVCAFVIALPKLLYKMLVYGKYKKSLAVRFGLKKPHVPGEGPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCE
VWFHGASVGEVRLLLPVLEKFCEEFPGWRCLVTSCTELGVQVASQVFIPMGATVSILPLD
EEEECCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECC
FSIIIKSVVAKLRPSLAVFSEGDCWLNFIEEAKRIGATTLVINGRISIDSSKRFKFLKRL
HHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCEEEEEEEEEEECCHHHHHHHHHH
GKNYFSPVDGFLLQDEVQKQRFLSLGIPEHKLQVTGNIKTYVAAQTALHLERETWRDRLR
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHC
LPTDSKLVILGSMHRSDAGKWLPVVQKLIKEGVSVLWVPRHVEKTKDVEESLHRLHIPYG
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHEECCCH
LWSRGANFSYVPVVVVDEIGLLKQLYVAGDLAFVGGTFDPKIGGHNLLEPLQCEVPLIFG
HHCCCCCCEEEEEEEECHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEC
PHITSQSELAQRLLLSGAGLCLDEIEPIIDTVSFLLNNQEVREAYVQKGKVFVKAETASF
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCH
DRTWRALKSYIPLYKNS
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMLRGVHRIFKCFYDVVLVCAFVIALPKLLYKMLVYGKYKKSLAVRFGLKKPHVPGEGPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCE
VWFHGASVGEVRLLLPVLEKFCEEFPGWRCLVTSCTELGVQVASQVFIPMGATVSILPLD
EEEECCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECC
FSIIIKSVVAKLRPSLAVFSEGDCWLNFIEEAKRIGATTLVINGRISIDSSKRFKFLKRL
HHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCEEEEEEEEEEECCHHHHHHHHHH
GKNYFSPVDGFLLQDEVQKQRFLSLGIPEHKLQVTGNIKTYVAAQTALHLERETWRDRLR
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHC
LPTDSKLVILGSMHRSDAGKWLPVVQKLIKEGVSVLWVPRHVEKTKDVEESLHRLHIPYG
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHEECCCH
LWSRGANFSYVPVVVVDEIGLLKQLYVAGDLAFVGGTFDPKIGGHNLLEPLQCEVPLIFG
HHCCCCCCEEEEEEEECHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEC
PHITSQSELAQRLLLSGAGLCLDEIEPIIDTVSFLLNNQEVREAYVQKGKVFVKAETASF
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCH
DRTWRALKSYIPLYKNS
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8748024; 10192388; 10684935; 10871362; 9765820 [H]