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The map label for this gene is rpiA

Identifier: 15835676

GI number: 15835676

Start: 174818

End: 175513

Strand: Reverse

Name: rpiA

Synonym: CPj0141

Alternate gene names: 15835676

Gene position: 175513-174818 (Counterclockwise)

Preceding gene: 15835677

Following gene: 15835675

Centisome position: 14.31

GC content: 40.8

Gene sequence:

>696_bases
GTGGAAAAAGATCTTCATCTTCATGAGAAAAAATGCCTGGCCCATGAGGCTGCTACACAAGTAACTTCAGGCATGATTCT
TGGCTTAGGCAGTGGATCTACAGCTAAGGAATTTATCTTTGCACTCGCCCATAGAATTCAAACAGAGTCCTTAGCAGTTC
ATGCTATAGCTTCTTCTCAAAATTCTTATGCTCTAGCAAAGCAGCTTGCCATCCCCCTCTTAAACCCAGAAAAATTCTCT
TCCCTAGATCTTACGGTAGACGGTGCTGATGAAGTCGACCCTCAATTGCGGATGATCAAAGGTGGTGGCGGAGCCATTTT
CAGAGAAAAGATTCTTTTAAGAGCAGCAAAACGCAGCATTATCCTTGTTGATGAAAGTAAACTGGTTCCAGTCCTAGGAA
AATTTCGTGTTCCTTTAGAAATCAGTCGATTCGGTCGCTCAGCAATTATTGAAGAAATCCGCCATCTTGGATATGAAGGA
GAATGGCGCCTACAAGATACTGGTGACCTATTTATTACAGACAGCAGCAACTACATTTACGATATTTTTTCCCCCAACTC
CTACCCAAATCCTGAAAAGGATTTATTAAAGTTAATACAAATTCATGGTGTTATTGAAGTCGGGTTTGTTATAGAGAAAG
TCGAAGTGTGGTCTAGCAATAGCCAAGGTCTAATCAGCAAAAAATATTCTGTATGA

Upstream 100 bases:

>100_bases
TACCCTAAAGACTCGTCCAAAAGGTTTCGATTTTTGTATAGTATTGGAAGAATCCCTTTGCATAAGCTGTGGGAATATTT
TGTAACATAGTAGTAGCGCT

Downstream 100 bases:

>100_bases
GCTTAGAAAAAGAACTCCTAGAAGAAACCCCCTTAGTACTTCTCAATTTTTACAAACTTGTCAGTTTTTGTAATTATGCA
GGCATGATCTTAGGTACTGA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MEKDLHLHEKKCLAHEAATQVTSGMILGLGSGSTAKEFIFALAHRIQTESLAVHAIASSQNSYALAKQLAIPLLNPEKFS
SLDLTVDGADEVDPQLRMIKGGGGAIFREKILLRAAKRSIILVDESKLVPVLGKFRVPLEISRFGRSAIIEEIRHLGYEG
EWRLQDTGDLFITDSSNYIYDIFSPNSYPNPEKDLLKLIQIHGVIEVGFVIEKVEVWSSNSQGLISKKYSV

Sequences:

>Translated_231_residues
MEKDLHLHEKKCLAHEAATQVTSGMILGLGSGSTAKEFIFALAHRIQTESLAVHAIASSQNSYALAKQLAIPLLNPEKFS
SLDLTVDGADEVDPQLRMIKGGGGAIFREKILLRAAKRSIILVDESKLVPVLGKFRVPLEISRFGRSAIIEEIRHLGYEG
EWRLQDTGDLFITDSSNYIYDIFSPNSYPNPEKDLLKLIQIHGVIEVGFVIEKVEVWSSNSQGLISKKYSV
>Mature_231_residues
MEKDLHLHEKKCLAHEAATQVTSGMILGLGSGSTAKEFIFALAHRIQTESLAVHAIASSQNSYALAKQLAIPLLNPEKFS
SLDLTVDGADEVDPQLRMIKGGGGAIFREKILLRAAKRSIILVDESKLVPVLGKFRVPLEISRFGRSAIIEEIRHLGYEG
EWRLQDTGDLFITDSSNYIYDIFSPNSYPNPEKDLLKLIQIHGVIEVGFVIEKVEVWSSNSQGLISKKYSV

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=214, Percent_Identity=30.8411214953271, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1789280, Length=206, Percent_Identity=36.8932038834951, Blast_Score=110, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17551758, Length=206, Percent_Identity=31.5533980582524, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324669, Length=215, Percent_Identity=31.6279069767442, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364072, Length=195, Percent_Identity=30.2564102564103, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_CHLPN (Q9Z942)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B72115
- PIR:   E86508
- RefSeq:   NP_224349.1
- RefSeq:   NP_300200.1
- RefSeq:   NP_445173.1
- RefSeq:   NP_876418.1
- ProteinModelPortal:   Q9Z942
- SMR:   Q9Z942
- GeneID:   1466825
- GeneID:   894925
- GeneID:   918930
- GeneID:   963273
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0631
- KEGG:   cpn:CPn0141
- KEGG:   cpt:CpB0142
- TIGR:   CP_0631
- HOGENOM:   HBG515603
- OMA:   DLNHTGN
- PhylomeDB:   Q9Z942
- ProtClustDB:   PRK00702
- BioCyc:   CPNE115711:CP_0631-MONOMER
- BioCyc:   CPNE115713:CPN0141-MONOMER
- BioCyc:   CPNE138677:CPJ0141-MONOMER
- BioCyc:   CPNE182082:CPB0142-MONOMER
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25575; Mature: 25575

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDLHLHEKKCLAHEAATQVTSGMILGLGSGSTAKEFIFALAHRIQTESLAVHAIASSQ
CCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
NSYALAKQLAIPLLNPEKFSSLDLTVDGADEVDPQLRMIKGGGGAIFREKILLRAAKRSI
CCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEE
ILVDESKLVPVLGKFRVPLEISRFGRSAIIEEIRHLGYEGEWRLQDTGDLFITDSSNYIY
EEEECCCCCCHHCCCCCCEEHHHCCHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCEEE
DIFSPNSYPNPEKDLLKLIQIHGVIEVGFVIEKVEVWSSNSQGLISKKYSV
EEECCCCCCCCHHHHHHHHHHHCHHEEHHEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MEKDLHLHEKKCLAHEAATQVTSGMILGLGSGSTAKEFIFALAHRIQTESLAVHAIASSQ
CCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
NSYALAKQLAIPLLNPEKFSSLDLTVDGADEVDPQLRMIKGGGGAIFREKILLRAAKRSI
CCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCEE
ILVDESKLVPVLGKFRVPLEISRFGRSAIIEEIRHLGYEGEWRLQDTGDLFITDSSNYIY
EEEECCCCCCHHCCCCCCEEHHHCCHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCEEE
DIFSPNSYPNPEKDLLKLIQIHGVIEVGFVIEKVEVWSSNSQGLISKKYSV
EEECCCCCCCCHHHHHHHHHHHCHHEEHHEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362