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Identifier: 16752921

GI number: 16752921

Start: 685232

End: 687430

Strand: Direct

Name: Not Available

Synonym: CP0650

Alternate gene names: 16752921

Gene position: 685232-687430 (Clockwise)

Preceding gene: 16752916

Following gene: 16752933

Centisome position: 55.72

GC content: 39.65

Gene sequence:

>2199_bases
ATGGAGAAAATCTGCGGATACTTAGAGCAAATACTTGTTGAAAACAAAGACTCTGGGGACATTACTGCTTATATCAAAAT
ACCCAATAAAACGACTCCTATCCTAATTAAAGGCAAACTTCCCCAACCTTTGGAACTAGGATCCCCGATCCAAATCTATG
GTGTCTGGAGCCATTCCCCTTCAAATACTAAGTATTTCCAAATCCATAGTTACGACTCTCCTCTTCTTTATGAATATCGT
GGCGTATTCCATTACCTCACCTCAAAACTCATCAAAGGAATCGGCCCTAAAATCGCAGAAAAGATCATCGAGAAATTTCA
AGAGAAAACATGTTATGTCCTCGATATCACTCCAGAACGCTTAAGTGAGGTTTCTGGAATTAGCGAAACACGATGTGTCT
CTATTTGCAAACAACTCTGCGAGCAAAAAATCTTAAGGAAAACTCTTCTCTTTCTCCAAGAATACAATATCCCGATTCAT
TATGGAGTGAGAATTTTTAAAAAATACCAAGAGAAATCCATAGAAAAAATTTGCGAAGATCCCTTCCTTCTAGCCAGAGA
AATGGAGGGCATCGGATTCAAAACTGCTGATTTCATAGCTATGAAACTAGGCGTCCCCAGAAATTCTGAAAGTCGCCTAT
GTGCTGGTATCCAGCACTCCTTAGAAGAACTTCAAGAAGAAGGTCATACTTGCTATCCGATAGAGCTCCTGATAGATGTC
GTCGCCAAACTATTAAATCAAGATGTCTTTGATACTCCTATTACTCTCGAAGAAATCGATACGCAAATCCTCAATATGCA
AAAGCGTAAGCTTTTACATATTCAAGACATTTCTGGGACACTCCATGTCTGGACACGTTATCTCCATCTCGCAGAGAAAA
CTATTGTTTCTGATCTCAAGCGCATTTTATTTTCTTCGAGGAGAATCCGTTCTATAGACGGAGAAAAAGCAATTGCTTGG
GTAGAGGAAAACCTAAGTATAGATCTCGCAGAACAACAACGAGAAGCAATTAAAGCCTGTTTTTCTGAAAAACTTCTCAT
CATTACTGGGGGCCCTGGAACTGGAAAAAGTACCATTACCCAAGCAATACTGAAAATTTTTGAACAGGTGACTCATAAAA
TCATCCTCGCAGCTCCTACAGGAAAAGCCGCTAAACGGATGACCGAAATTACACAAAAACACTCCGTCACCATTCATGCT
CTGCTACAGTATGATTTTAAAACGAAATCTTTCCGCAAGAACCATGACAATCCTATAGACTGTGATCTGATCATTGTTGA
CGAATCCGGAATGATGGACACGCACTTGCTGCACCACTTCCTGAAAGCACTTCCTGACTACACAACTCTTGTCTTTATTG
GAGACATTCACCAGCTACCCAGCGTGGGCCCAGGAAATATCCTTAAAGACTTGATTACTTCGAATAAAATGACAGTCATC
AGATTAAATAAGATCTTCCGCCAAGTTCATGATTCGGGAATCGTTACGAATGCCCATAGGGTAAATGAAGGGGAACTCCC
CATATTATATTCAGAAACAGGGCGTCGTGATTTCTTATTTTTCCAAAAGGATGATCAAGAAGAGGCTCTCAATCATATCA
TTCATCTTGTGACAAAATTCGTCCCACAAAAATACCATATCTATCCTCAAGATATCCAAGTACTAGCTCCCATGAAAAAA
GGAACCCTAGGAATCTATAATCTAAATAAAGCACTCAAACATGCATTAAACCCTAAAAAAGCAAATCTTCACGGTAGATT
TCAATCCTATGCCGTTGGCGATAAGGTAATGCAAATCCGCAACAACTATAATAAAGAAGTCTTTAACGGCGATATAGGCT
ATGTCTCTACAATCAACTTCGAAGATAAAGCTGTTGTTGTCCGTATGGAAGGAAAGCATGTCGGCTATTCTTTCTCAGAG
CTTGACGATCTAGTCTTAGCCTATGCTACCTCAGTACATAAGTACCAGGGAAGTGAAAGCCCCTGCATTATCATTCCTAT
TCATACCTCGCACTTTATGATGCTCTATAGAAATCTTCTCTATACTGCTATTACGCGGGGGAAAAAATTGGTGATTCTAG
TTGGGACAAAAAAAGCCATTGCTATTGCAACAAGAAATAATCGAGTGCAACACCGATGTACAGGACTAGCAGAAGTTCTT
AAAGAGCTCGATACTAAGAAAAATTATGCAGATCTGTAA

Upstream 100 bases:

>100_bases
TTTTTATCTCAAAAAGTTTATAATCCATACTTTTTAGAAGCTTTTTATAAAGATTCCTTAAGCTACTTCATCTTCCAGGA
AAACAAGATTTTAGAATTCT

Downstream 100 bases:

>100_bases
TTACACCTACAGATCAGGATTCTAAAAAGAAAAGACCTCGAGCTCTACTCTACAGTAGTAAATAATAACCTGGGGGACTT
CAAATGAAATTCTTCGTTTA

Product: exodeoxyribonuclease V, alpha subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MEKICGYLEQILVENKDSGDITAYIKIPNKTTPILIKGKLPQPLELGSPIQIYGVWSHSPSNTKYFQIHSYDSPLLYEYR
GVFHYLTSKLIKGIGPKIAEKIIEKFQEKTCYVLDITPERLSEVSGISETRCVSICKQLCEQKILRKTLLFLQEYNIPIH
YGVRIFKKYQEKSIEKICEDPFLLAREMEGIGFKTADFIAMKLGVPRNSESRLCAGIQHSLEELQEEGHTCYPIELLIDV
VAKLLNQDVFDTPITLEEIDTQILNMQKRKLLHIQDISGTLHVWTRYLHLAEKTIVSDLKRILFSSRRIRSIDGEKAIAW
VEENLSIDLAEQQREAIKACFSEKLLIITGGPGTGKSTITQAILKIFEQVTHKIILAAPTGKAAKRMTEITQKHSVTIHA
LLQYDFKTKSFRKNHDNPIDCDLIIVDESGMMDTHLLHHFLKALPDYTTLVFIGDIHQLPSVGPGNILKDLITSNKMTVI
RLNKIFRQVHDSGIVTNAHRVNEGELPILYSETGRRDFLFFQKDDQEEALNHIIHLVTKFVPQKYHIYPQDIQVLAPMKK
GTLGIYNLNKALKHALNPKKANLHGRFQSYAVGDKVMQIRNNYNKEVFNGDIGYVSTINFEDKAVVVRMEGKHVGYSFSE
LDDLVLAYATSVHKYQGSESPCIIIPIHTSHFMMLYRNLLYTAITRGKKLVILVGTKKAIAIATRNNRVQHRCTGLAEVL
KELDTKKNYADL

Sequences:

>Translated_732_residues
MEKICGYLEQILVENKDSGDITAYIKIPNKTTPILIKGKLPQPLELGSPIQIYGVWSHSPSNTKYFQIHSYDSPLLYEYR
GVFHYLTSKLIKGIGPKIAEKIIEKFQEKTCYVLDITPERLSEVSGISETRCVSICKQLCEQKILRKTLLFLQEYNIPIH
YGVRIFKKYQEKSIEKICEDPFLLAREMEGIGFKTADFIAMKLGVPRNSESRLCAGIQHSLEELQEEGHTCYPIELLIDV
VAKLLNQDVFDTPITLEEIDTQILNMQKRKLLHIQDISGTLHVWTRYLHLAEKTIVSDLKRILFSSRRIRSIDGEKAIAW
VEENLSIDLAEQQREAIKACFSEKLLIITGGPGTGKSTITQAILKIFEQVTHKIILAAPTGKAAKRMTEITQKHSVTIHA
LLQYDFKTKSFRKNHDNPIDCDLIIVDESGMMDTHLLHHFLKALPDYTTLVFIGDIHQLPSVGPGNILKDLITSNKMTVI
RLNKIFRQVHDSGIVTNAHRVNEGELPILYSETGRRDFLFFQKDDQEEALNHIIHLVTKFVPQKYHIYPQDIQVLAPMKK
GTLGIYNLNKALKHALNPKKANLHGRFQSYAVGDKVMQIRNNYNKEVFNGDIGYVSTINFEDKAVVVRMEGKHVGYSFSE
LDDLVLAYATSVHKYQGSESPCIIIPIHTSHFMMLYRNLLYTAITRGKKLVILVGTKKAIAIATRNNRVQHRCTGLAEVL
KELDTKKNYADL
>Mature_732_residues
MEKICGYLEQILVENKDSGDITAYIKIPNKTTPILIKGKLPQPLELGSPIQIYGVWSHSPSNTKYFQIHSYDSPLLYEYR
GVFHYLTSKLIKGIGPKIAEKIIEKFQEKTCYVLDITPERLSEVSGISETRCVSICKQLCEQKILRKTLLFLQEYNIPIH
YGVRIFKKYQEKSIEKICEDPFLLAREMEGIGFKTADFIAMKLGVPRNSESRLCAGIQHSLEELQEEGHTCYPIELLIDV
VAKLLNQDVFDTPITLEEIDTQILNMQKRKLLHIQDISGTLHVWTRYLHLAEKTIVSDLKRILFSSRRIRSIDGEKAIAW
VEENLSIDLAEQQREAIKACFSEKLLIITGGPGTGKSTITQAILKIFEQVTHKIILAAPTGKAAKRMTEITQKHSVTIHA
LLQYDFKTKSFRKNHDNPIDCDLIIVDESGMMDTHLLHHFLKALPDYTTLVFIGDIHQLPSVGPGNILKDLITSNKMTVI
RLNKIFRQVHDSGIVTNAHRVNEGELPILYSETGRRDFLFFQKDDQEEALNHIIHLVTKFVPQKYHIYPQDIQVLAPMKK
GTLGIYNLNKALKHALNPKKANLHGRFQSYAVGDKVMQIRNNYNKEVFNGDIGYVSTINFEDKAVVVRMEGKHVGYSFSE
LDDLVLAYATSVHKYQGSESPCIIIPIHTSHFMMLYRNLLYTAITRGKKLVILVGTKKAIAIATRNNRVQHRCTGLAEVL
KELDTKKNYADL

Specific function: Exhibits Several Catalytic Activities, Including ATP-Dependent Exonuclease, ATP-Stimulated Endonuclease, ATP-Dependent Unwinding And DNA-Dependent ATPase Activities. Strand Cleavage Occurs 5' To 3' During The Unwinding Of Duplex DNA At Chi Sequences, Whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789182, Length=415, Percent_Identity=26.2650602409639, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006345 [H]

Pfam domain/function: NA

EC number: 3.1.11.5

Molecular weight: Translated: 83438; Mature: 83438

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKICGYLEQILVENKDSGDITAYIKIPNKTTPILIKGKLPQPLELGSPIQIYGVWSHSP
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCC
SNTKYFQIHSYDSPLLYEYRGVFHYLTSKLIKGIGPKIAEKIIEKFQEKTCYVLDITPER
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCHHH
LSEVSGISETRCVSICKQLCEQKILRKTLLFLQEYNIPIHYGVRIFKKYQEKSIEKICED
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PFLLAREMEGIGFKTADFIAMKLGVPRNSESRLCAGIQHSLEELQEEGHTCYPIELLIDV
HHHHHHHHCCCCCCHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
VAKLLNQDVFDTPITLEEIDTQILNMQKRKLLHIQDISGTLHVWTRYLHLAEKTIVSDLK
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RILFSSRRIRSIDGEKAIAWVEENLSIDLAEQQREAIKACFSEKLLIITGGPGTGKSTIT
HHHHCCCHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
QAILKIFEQVTHKIILAAPTGKAAKRMTEITQKHSVTIHALLQYDFKTKSFRKNHDNPID
HHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHCCCCCCCC
CDLIIVDESGMMDTHLLHHFLKALPDYTTLVFIGDIHQLPSVGPGNILKDLITSNKMTVI
EEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECHHHCCCCCCHHHHHHHHCCCCEEEE
RLNKIFRQVHDSGIVTNAHRVNEGELPILYSETGRRDFLFFQKDDQEEALNHIIHLVTKF
HHHHHHHHHHCCCCEECCCCCCCCCCEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHH
VPQKYHIYPQDIQVLAPMKKGTLGIYNLNKALKHALNPKKANLHGRFQSYAVGDKVMQIR
CCCCEEECCCCHHEEECCCCCCEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
NNYNKEVFNGDIGYVSTINFEDKAVVVRMEGKHVGYSFSELDDLVLAYATSVHKYQGSES
HCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PCIIIPIHTSHFMMLYRNLLYTAITRGKKLVILVGTKKAIAIATRNNRVQHRCTGLAEVL
CEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHH
KELDTKKNYADL
HHHHCCCCCCCC
>Mature Secondary Structure
MEKICGYLEQILVENKDSGDITAYIKIPNKTTPILIKGKLPQPLELGSPIQIYGVWSHSP
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCC
SNTKYFQIHSYDSPLLYEYRGVFHYLTSKLIKGIGPKIAEKIIEKFQEKTCYVLDITPER
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCHHH
LSEVSGISETRCVSICKQLCEQKILRKTLLFLQEYNIPIHYGVRIFKKYQEKSIEKICED
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PFLLAREMEGIGFKTADFIAMKLGVPRNSESRLCAGIQHSLEELQEEGHTCYPIELLIDV
HHHHHHHHCCCCCCHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
VAKLLNQDVFDTPITLEEIDTQILNMQKRKLLHIQDISGTLHVWTRYLHLAEKTIVSDLK
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RILFSSRRIRSIDGEKAIAWVEENLSIDLAEQQREAIKACFSEKLLIITGGPGTGKSTIT
HHHHCCCHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
QAILKIFEQVTHKIILAAPTGKAAKRMTEITQKHSVTIHALLQYDFKTKSFRKNHDNPID
HHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHCCCCCCCC
CDLIIVDESGMMDTHLLHHFLKALPDYTTLVFIGDIHQLPSVGPGNILKDLITSNKMTVI
EEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECHHHCCCCCCHHHHHHHHCCCCEEEE
RLNKIFRQVHDSGIVTNAHRVNEGELPILYSETGRRDFLFFQKDDQEEALNHIIHLVTKF
HHHHHHHHHHCCCCEECCCCCCCCCCEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHH
VPQKYHIYPQDIQVLAPMKKGTLGIYNLNKALKHALNPKKANLHGRFQSYAVGDKVMQIR
CCCCEEECCCCHHEEECCCCCCEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
NNYNKEVFNGDIGYVSTINFEDKAVVVRMEGKHVGYSFSELDDLVLAYATSVHKYQGSES
HCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PCIIIPIHTSHFMMLYRNLLYTAITRGKKLVILVGTKKAIAIATRNNRVQHRCTGLAEVL
CEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHH
KELDTKKNYADL
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: DNA-dependent ATPase activity; Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]