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Identifier: 16752248

GI number: 16752248

Start: 1174620

End: 1176527

Strand: Direct

Name: Not Available

Synonym: CP1079

Alternate gene names: 16752248

Gene position: 1174620-1176527 (Clockwise)

Preceding gene: 16752241

Following gene: 16752249

Centisome position: 95.51

GC content: 40.67

Gene sequence:

>1908_bases
ATGATCCCTTTTACTAAAACAATAGGGTTCCGTTTGTGGTTGGCTTGCGCCGTTGCTATCATTGCACCTCTAGGGATCAA
CATCGTATGGTTAAACCTAGATCAATACCGCACCATAGTCTCTGCTATTTCTACTGCACTGAAAGAAAACGCTGCTTTCA
AAGCCAATACTCTCACTCAGATTGTCCCTTTGAATGTCGATGTTCTATCTCTATTTTCTGATGTCTTAGATTTAGATGCT
GGTATTCCAGAGACTCCGAACGTTCTCCTTAGCAATGAAATGCAGAAAGTATTCCAAGGGATCTATAATGAAATCTCTTT
AATCAAGGTATTCCCAAATGGAGATAAAATTGTTGTTGCTTCTAGCATTCCTGAACACTTAGGGGAAAACTATAATCACA
AAATAGACATCCCTAAGAACACTCCATTTTTAGCAGCCCTAAAACAATCTCCTAAAAATCAGGAAGTCTTTTCTGTAATG
CAAGCTAATGTTTTTGATGCAAAAACTCAAGAACTCCAAGGGATCTTATACACCACGTTCAGTGCTGAGAGCTTACTCAA
AGATCTCCTGATAAACAAGCAATCCTATCTCACTGTAAAAACTGCGATCCTTTCCAAATACGGCGTTATCTTAAAAGCTT
CTGATCCTGCTCTCCATCTCCATACTGTCTACCCTGACATGACGAAAGAAAAATTCTGCCAAGTTTTTCTCAATGATGAT
CCTTGCCCTATAGACTCAGAATTAGGTCCTTTAACTCTCTCCCCTCTGGATATTGGAGAAAATTTCTATTCTTTTAAAAT
CAAAGATACTGAGATTTGGGGCTGTATTGAAAATGTTCCCAGTATAGATATTGCAGTCCTTTCCTATGCTAAAAAAGAAG
AGAGCTTTGCGCCTTTATGGCGCAGAGCTCGCATGTACACTGCCTATTTCTTTTGCATTCTCTTAGGGAGCCTCATAGCC
TTTATTGTAGCAAGACGATTGTCGTTACCTATCAGAAAACTTGCCACTGCGATGATAGAATCTAGGAAAAACAAAAACTG
CCTCTATACTGACGACTCCTTAGGGTTTGAGATCAACAGACTTGGCCATATTTTTAATGCTATGGTGGAGAATCTCCACA
AACAGCAACACCTCGCTAAGACGAACTTTGAGATGAAAGAAAATGCACAGAACGCTCTACATTTAGGAGAGCAGGCTCAG
CAGCGACTTCTTCCTAATACTCTCCCCAGCTATCCTCATATAGAACTCGCAAAAGCCTATATCCCTGCCATTACTGTAGG
TGGTGATTTCTTTGATGTTTTTGTTGTAGGAGAGGGTTCGAAGGCTCGCCTATTCCTGATTGTTGCTGACGCCTCAGGGA
AAGGTGTTAATGCTTGTGGGTATTCGCTATTTCTAAAAAATATGCTCAGAACATTCCTTTCTCGCTCTTCGTCTCTTCAA
CAGGCAATCCAAGAAACCTCACGCTTATTTTATAACAATACAAAAAACTCAGGGATGTTTGTCACTCTATGTGTGTACTG
TTATCATCAAACTTCCAACACCATGGAATATTATTCTTGTGGACATCCTCCTGCCTGCTACCTAGATCCTGATGGCGAGA
CTTCTTGGCTATTCCATCCTGGAATGGCTTTAGGCTTCCTTCCCGAAGTTGCGAACATCACTTCAAAGCTATTTCATCCT
AAGCCAGGGTCTCTCTTTGTCTTGTATTCTGATGGTATTACAGAAGCCCATAATAACAATAACGACATGTTTGGAGAAGA
GCGCCTACAAGCTGCAATTCAAGGATTGACAGGGAAAAGTGCTGCTGATGCCGTCCACAGGTTGATGTTAAGTGTAAAAA
CCTTTGTCGGGAACTCCCATCAACATGACGACATCACCTTATTAATATTAAAGGTATTAGAATCATGA

Upstream 100 bases:

>100_bases
TTAAGGAAATTTTTTTATACTGCGTAAGAAACAAAACACTAGAGGAAAGACGTTCCTTCTCAAGGATGACAAGCCTTAAG
AATAGAGCGCCGTAATACCC

Downstream 100 bases:

>100_bases
AACATACCTTTACCAAGCGTGTTCTATTTTTTTTCTTTTTAGTGATTCCCATTCCCCTACTCCTCAATCTTATGGTCGTA
GGTTTTTTCTCATTTTCTGC

Product: regulatory protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MIPFTKTIGFRLWLACAVAIIAPLGINIVWLNLDQYRTIVSAISTALKENAAFKANTLTQIVPLNVDVLSLFSDVLDLDA
GIPETPNVLLSNEMQKVFQGIYNEISLIKVFPNGDKIVVASSIPEHLGENYNHKIDIPKNTPFLAALKQSPKNQEVFSVM
QANVFDAKTQELQGILYTTFSAESLLKDLLINKQSYLTVKTAILSKYGVILKASDPALHLHTVYPDMTKEKFCQVFLNDD
PCPIDSELGPLTLSPLDIGENFYSFKIKDTEIWGCIENVPSIDIAVLSYAKKEESFAPLWRRARMYTAYFFCILLGSLIA
FIVARRLSLPIRKLATAMIESRKNKNCLYTDDSLGFEINRLGHIFNAMVENLHKQQHLAKTNFEMKENAQNALHLGEQAQ
QRLLPNTLPSYPHIELAKAYIPAITVGGDFFDVFVVGEGSKARLFLIVADASGKGVNACGYSLFLKNMLRTFLSRSSSLQ
QAIQETSRLFYNNTKNSGMFVTLCVYCYHQTSNTMEYYSCGHPPACYLDPDGETSWLFHPGMALGFLPEVANITSKLFHP
KPGSLFVLYSDGITEAHNNNNDMFGEERLQAAIQGLTGKSAADAVHRLMLSVKTFVGNSHQHDDITLLILKVLES

Sequences:

>Translated_635_residues
MIPFTKTIGFRLWLACAVAIIAPLGINIVWLNLDQYRTIVSAISTALKENAAFKANTLTQIVPLNVDVLSLFSDVLDLDA
GIPETPNVLLSNEMQKVFQGIYNEISLIKVFPNGDKIVVASSIPEHLGENYNHKIDIPKNTPFLAALKQSPKNQEVFSVM
QANVFDAKTQELQGILYTTFSAESLLKDLLINKQSYLTVKTAILSKYGVILKASDPALHLHTVYPDMTKEKFCQVFLNDD
PCPIDSELGPLTLSPLDIGENFYSFKIKDTEIWGCIENVPSIDIAVLSYAKKEESFAPLWRRARMYTAYFFCILLGSLIA
FIVARRLSLPIRKLATAMIESRKNKNCLYTDDSLGFEINRLGHIFNAMVENLHKQQHLAKTNFEMKENAQNALHLGEQAQ
QRLLPNTLPSYPHIELAKAYIPAITVGGDFFDVFVVGEGSKARLFLIVADASGKGVNACGYSLFLKNMLRTFLSRSSSLQ
QAIQETSRLFYNNTKNSGMFVTLCVYCYHQTSNTMEYYSCGHPPACYLDPDGETSWLFHPGMALGFLPEVANITSKLFHP
KPGSLFVLYSDGITEAHNNNNDMFGEERLQAAIQGLTGKSAADAVHRLMLSVKTFVGNSHQHDDITLLILKVLES
>Mature_635_residues
MIPFTKTIGFRLWLACAVAIIAPLGINIVWLNLDQYRTIVSAISTALKENAAFKANTLTQIVPLNVDVLSLFSDVLDLDA
GIPETPNVLLSNEMQKVFQGIYNEISLIKVFPNGDKIVVASSIPEHLGENYNHKIDIPKNTPFLAALKQSPKNQEVFSVM
QANVFDAKTQELQGILYTTFSAESLLKDLLINKQSYLTVKTAILSKYGVILKASDPALHLHTVYPDMTKEKFCQVFLNDD
PCPIDSELGPLTLSPLDIGENFYSFKIKDTEIWGCIENVPSIDIAVLSYAKKEESFAPLWRRARMYTAYFFCILLGSLIA
FIVARRLSLPIRKLATAMIESRKNKNCLYTDDSLGFEINRLGHIFNAMVENLHKQQHLAKTNFEMKENAQNALHLGEQAQ
QRLLPNTLPSYPHIELAKAYIPAITVGGDFFDVFVVGEGSKARLFLIVADASGKGVNACGYSLFLKNMLRTFLSRSSSLQ
QAIQETSRLFYNNTKNSGMFVTLCVYCYHQTSNTMEYYSCGHPPACYLDPDGETSWLFHPGMALGFLPEVANITSKLFHP
KPGSLFVLYSDGITEAHNNNNDMFGEERLQAAIQGLTGKSAADAVHRLMLSVKTFVGNSHQHDDITLLILKVLES

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 70794; Mature: 70794

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPFTKTIGFRLWLACAVAIIAPLGINIVWLNLDQYRTIVSAISTALKENAAFKANTLTQ
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCEECCCCEE
IVPLNVDVLSLFSDVLDLDAGIPETPNVLLSNEMQKVFQGIYNEISLIKVFPNGDKIVVA
EEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEE
SSIPEHLGENYNHKIDIPKNTPFLAALKQSPKNQEVFSVMQANVFDAKTQELQGILYTTF
CCCHHHCCCCCCCEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCEEEEEEC
SAESLLKDLLINKQSYLTVKTAILSKYGVILKASDPALHLHTVYPDMTKEKFCQVFLNDD
CHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCHHHHHHEEECCC
PCPIDSELGPLTLSPLDIGENFYSFKIKDTEIWGCIENVPSIDIAVLSYAKKEESFAPLW
CCCCCCCCCCEEECCHHCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHHHHCCHHHHHH
RRARMYTAYFFCILLGSLIAFIVARRLSLPIRKLATAMIESRKNKNCLYTDDSLGFEINR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCEEHHH
LGHIFNAMVENLHKQQHLAKTNFEMKENAQNALHLGEQAQQRLLPNTLPSYPHIELAKAY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
IPAITVGGDFFDVFVVGEGSKARLFLIVADASGKGVNACGYSLFLKNMLRTFLSRSSSLQ
CCEEEECCCEEEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
QAIQETSRLFYNNTKNSGMFVTLCVYCYHQTSNTMEYYSCGHPPACYLDPDGETSWLFHP
HHHHHHHHHHCCCCCCCCEEEEEEEHHHHCCCCCEEEEECCCCCEEEECCCCCEEEEECC
GMALGFLPEVANITSKLFHPKPGSLFVLYSDGITEAHNNNNDMFGEERLQAAIQGLTGKS
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCH
AADAVHRLMLSVKTFVGNSHQHDDITLLILKVLES
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIPFTKTIGFRLWLACAVAIIAPLGINIVWLNLDQYRTIVSAISTALKENAAFKANTLTQ
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCEECCCCEE
IVPLNVDVLSLFSDVLDLDAGIPETPNVLLSNEMQKVFQGIYNEISLIKVFPNGDKIVVA
EEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEE
SSIPEHLGENYNHKIDIPKNTPFLAALKQSPKNQEVFSVMQANVFDAKTQELQGILYTTF
CCCHHHCCCCCCCEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCEEEEEEC
SAESLLKDLLINKQSYLTVKTAILSKYGVILKASDPALHLHTVYPDMTKEKFCQVFLNDD
CHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCHHHHHHEEECCC
PCPIDSELGPLTLSPLDIGENFYSFKIKDTEIWGCIENVPSIDIAVLSYAKKEESFAPLW
CCCCCCCCCCEEECCHHCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHHHHCCHHHHHH
RRARMYTAYFFCILLGSLIAFIVARRLSLPIRKLATAMIESRKNKNCLYTDDSLGFEINR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCEEHHH
LGHIFNAMVENLHKQQHLAKTNFEMKENAQNALHLGEQAQQRLLPNTLPSYPHIELAKAY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
IPAITVGGDFFDVFVVGEGSKARLFLIVADASGKGVNACGYSLFLKNMLRTFLSRSSSLQ
CCEEEECCCEEEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
QAIQETSRLFYNNTKNSGMFVTLCVYCYHQTSNTMEYYSCGHPPACYLDPDGETSWLFHP
HHHHHHHHHHCCCCCCCCEEEEEEEHHHHCCCCCEEEEECCCCCEEEECCCCCEEEEECC
GMALGFLPEVANITSKLFHPKPGSLFVLYSDGITEAHNNNNDMFGEERLQAAIQGLTGKS
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCH
AADAVHRLMLSVKTFVGNSHQHDDITLLILKVLES
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]