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Identifier: 16752177

GI number: 16752177

Start: 1090569

End: 1091723

Strand: Direct

Name: Not Available

Synonym: CP1007

Alternate gene names: 16752177

Gene position: 1090569-1091723 (Clockwise)

Preceding gene: 16752176

Following gene: 16752178

Centisome position: 88.67

GC content: 43.98

Gene sequence:

>1155_bases
ATGGAAAAACCACAAAATCGAAAAGCACCCAGAATTTTTTGGTTAAACAACCAAGTCGCTATTCCTCCTTCTGAGCGGGT
TAAAGAAAGTTATGCCCTACACTCGGACATATTTTCTCTACCCCCCGGCTCCGCGTTAAAATTAGCTGAGAAAACAGAGG
AGAGTATCCGACAGTTGGTCGGATTGAAAGACTCTCATATTTTTCGTTTTGTCCCTCATTTCCCTCATGTGGTTCATATA
GTCCTGGCAGCCCTTGTAGAAAATCTGTCCATGTTTCAAGGAAGAAATCACATCATTCTTCCTGCTCATGATCAACAGCT
TTTAATTAATAGCCTATGTCGCCATCAAGGACTCGGAACTACCTATGACTGGGTAACAGTAAATCACGAAGGTAGGATTG
TTGAAGAACAGCTTATAGAAACCTTGAGTCCACGTAGTTTGTTATTCTCACTATCTGCAGCTCATGGATTGACAGGGGTA
ATCCAACCCTTAGATCCTCTGCTCTCCTTATGCAAAGACCGCAGAATCCTCCTTCACTTGGATATTTCTGACATTTTAGG
AAGAGCTCCTCTAACTCCTGAGATCCTCAACGCTGACATCATTACTTTCTCTTCAGCAGCTCTTGGAGGTATGGGCTCTA
TCGGGGGGATCTTCATTCGTAAATCTTTAGAGAGGGTCTTTTCTTCCTGGTTTCCACCTCACACTTCAGCATCTTTATGT
TTCAGTGCGGTGGCAGCAATGCAAACTGCGTGTGAAGAACGTATTTCCGCTCTTCCGCTTTTCACATTCCACACCTCCAA
TTTGTGTAAAAAGCTAATTCAAGAGTTACAAAGCGTCCTCCCCTCAATCCAATTGGCATTTTCCGAGGTCCAGAACCGAT
TACCTAATATCGTTGTTGCTGCAATTCCTGACATCCCAGCAGAGAGTCTTGCCTTCCATCTCCACCAGCAAGGCATCTAT
CCATCCTTAGGATACGAGAGATTCCAGCCCCTAGCTCAAGTGTTACAAAATTGTGGGATCTCCCCGTTCTTATGTCACAG
TGCCTTACATTTCTCTCTTACAGAAAGAAGTAAAGACCTCGAGTTTTCCAAACTTGCTCGTGCCATGCATGATGCCATTA
AGCATCTTACCCCTTTACTTGGAAGTTCCTCATGA

Upstream 100 bases:

>100_bases
ACGGAAATTCCTTACGCTCTTTGATTATGGATCTAGAAAAATTAAGTGAGGAAGAGGTACTATCTTTAGAATTACCGACG
GGAAAACCAGTTGTATATCA

Downstream 100 bases:

>100_bases
CCCTACCTCTAGAACCAATGATTTTTTGGTCCTCGCTATCAGCAAAAGTTATGAAAAAATTCCTTACACCACATTGTGCG
GGCACGTTTTCTGAAGAGGA

Product: nifS protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MEKPQNRKAPRIFWLNNQVAIPPSERVKESYALHSDIFSLPPGSALKLAEKTEESIRQLVGLKDSHIFRFVPHFPHVVHI
VLAALVENLSMFQGRNHIILPAHDQQLLINSLCRHQGLGTTYDWVTVNHEGRIVEEQLIETLSPRSLLFSLSAAHGLTGV
IQPLDPLLSLCKDRRILLHLDISDILGRAPLTPEILNADIITFSSAALGGMGSIGGIFIRKSLERVFSSWFPPHTSASLC
FSAVAAMQTACEERISALPLFTFHTSNLCKKLIQELQSVLPSIQLAFSEVQNRLPNIVVAAIPDIPAESLAFHLHQQGIY
PSLGYERFQPLAQVLQNCGISPFLCHSALHFSLTERSKDLEFSKLARAMHDAIKHLTPLLGSSS

Sequences:

>Translated_384_residues
MEKPQNRKAPRIFWLNNQVAIPPSERVKESYALHSDIFSLPPGSALKLAEKTEESIRQLVGLKDSHIFRFVPHFPHVVHI
VLAALVENLSMFQGRNHIILPAHDQQLLINSLCRHQGLGTTYDWVTVNHEGRIVEEQLIETLSPRSLLFSLSAAHGLTGV
IQPLDPLLSLCKDRRILLHLDISDILGRAPLTPEILNADIITFSSAALGGMGSIGGIFIRKSLERVFSSWFPPHTSASLC
FSAVAAMQTACEERISALPLFTFHTSNLCKKLIQELQSVLPSIQLAFSEVQNRLPNIVVAAIPDIPAESLAFHLHQQGIY
PSLGYERFQPLAQVLQNCGISPFLCHSALHFSLTERSKDLEFSKLARAMHDAIKHLTPLLGSSS
>Mature_384_residues
MEKPQNRKAPRIFWLNNQVAIPPSERVKESYALHSDIFSLPPGSALKLAEKTEESIRQLVGLKDSHIFRFVPHFPHVVHI
VLAALVENLSMFQGRNHIILPAHDQQLLINSLCRHQGLGTTYDWVTVNHEGRIVEEQLIETLSPRSLLFSLSAAHGLTGV
IQPLDPLLSLCKDRRILLHLDISDILGRAPLTPEILNADIITFSSAALGGMGSIGGIFIRKSLERVFSSWFPPHTSASLC
FSAVAAMQTACEERISALPLFTFHTSNLCKKLIQELQSVLPSIQLAFSEVQNRLPNIVVAAIPDIPAESLAFHLHQQGIY
PSLGYERFQPLAQVLQNCGISPFLCHSALHFSLTERSKDLEFSKLARAMHDAIKHLTPLLGSSS

Specific function: Catalyzes the removal of elemental sulfur from cysteine to produce alanine [H]

COG id: COG1104

COG function: function code E; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=300, Percent_Identity=22, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25143064, Length=385, Percent_Identity=22.3376623376623, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319831, Length=386, Percent_Identity=20.4663212435233, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129463, Length=177, Percent_Identity=27.683615819209, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010240
- InterPro:   IPR017773
- InterPro:   IPR016454
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 42588; Mature: 42588

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPQNRKAPRIFWLNNQVAIPPSERVKESYALHSDIFSLPPGSALKLAEKTEESIRQLV
CCCCCCCCCCEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GLKDSHIFRFVPHFPHVVHIVLAALVENLSMFQGRNHIILPAHDQQLLINSLCRHQGLGT
CCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCC
TYDWVTVNHEGRIVEEQLIETLSPRSLLFSLSAAHGLTGVIQPLDPLLSLCKDRRILLHL
EEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEE
DISDILGRAPLTPEILNADIITFSSAALGGMGSIGGIFIRKSLERVFSSWFPPHTSASLC
CHHHHHCCCCCCHHHHCCCHHEECHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
FSAVAAMQTACEERISALPLFTFHTSNLCKKLIQELQSVLPSIQLAFSEVQNRLPNIVVA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AIPDIPAESLAFHLHQQGIYPSLGYERFQPLAQVLQNCGISPFLCHSALHFSLTERSKDL
ECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
EFSKLARAMHDAIKHLTPLLGSSS
CHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKPQNRKAPRIFWLNNQVAIPPSERVKESYALHSDIFSLPPGSALKLAEKTEESIRQLV
CCCCCCCCCCEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GLKDSHIFRFVPHFPHVVHIVLAALVENLSMFQGRNHIILPAHDQQLLINSLCRHQGLGT
CCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCC
TYDWVTVNHEGRIVEEQLIETLSPRSLLFSLSAAHGLTGVIQPLDPLLSLCKDRRILLHL
EEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEE
DISDILGRAPLTPEILNADIITFSSAALGGMGSIGGIFIRKSLERVFSSWFPPHTSASLC
CHHHHHCCCCCCHHHHCCCHHEECHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
FSAVAAMQTACEERISALPLFTFHTSNLCKKLIQELQSVLPSIQLAFSEVQNRLPNIVVA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AIPDIPAESLAFHLHQQGIYPSLGYERFQPLAQVLQNCGISPFLCHSALHFSLTERSKDL
ECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
EFSKLARAMHDAIKHLTPLLGSSS
CHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA