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The map label for this gene is lacA

Identifier: 13357562

GI number: 13357562

Start: 4431

End: 4895

Strand: Direct

Name: lacA

Synonym: UU006

Alternate gene names: 13357562

Gene position: 4431-4895 (Clockwise)

Preceding gene: 13358171

Following gene: 13357563

Centisome position: 0.59

GC content: 30.54

Gene sequence:

>465_bases
ATGATAAAAAAAATTTATTTTGGTAATGATCATGCTGCTTATGAAATTAAAGATCAAATTATCACTCATTTAAAACAAAA
AGGTTATCAAATTATTGATGAAGGTGCACAAGCCGCATTAGGTTCTGTTGATTATAGTACATATGCATTAAAAGTTGCTA
ATGACGTTGTTAATGATACTAAAAATGATAGCATAGGTATTTTATTATGTGGCACGGGAATAGGTATGAATATAGCAGCA
AGCAAAGTGCATGGAACGCGGGTTGCGTTAGTGTATAACGAAAGCAGTGCAAAACTAGCCAAGGAGCATAATAATGCTAA
CATAATTACTATAGGAGCACGTGAAAATAGTTTAAACCAAATTCTTAAAATGATTGATGATTTTTTAACAAGTAAATTTT
TAGGCGAGCGTCACCAAAAACGTTTAGATATAATTGCAAAATATGAAAAAGAGCAAAATAGTTAA

Upstream 100 bases:

>100_bases
TGACATCGATAAATGAGAATACATTCGTCGTGGTGCTAATGTTGAGATGGTAGATATGTTTATTAAAGAACTAAAAGATA
ATAAAACAGGGAAATAATCA

Downstream 100 bases:

>100_bases
TTTTAAAAGTTTTTTTAATTTTTTTAACATTTTGTGTTCATTTTGTAGTAATATAAAAGTGCAATAAAATATTAATATTA
AAGAAAGATTATATTATGTT

Product: galactoside O-acetyltransferase

Products: NA

Alternate protein names: Phosphoriboisomerase B [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIKKIYFGNDHAAYEIKDQIITHLKQKGYQIIDEGAQAALGSVDYSTYALKVANDVVNDTKNDSIGILLCGTGIGMNIAA
SKVHGTRVALVYNESSAKLAKEHNNANIITIGARENSLNQILKMIDDFLTSKFLGERHQKRLDIIAKYEKEQNS

Sequences:

>Translated_154_residues
MIKKIYFGNDHAAYEIKDQIITHLKQKGYQIIDEGAQAALGSVDYSTYALKVANDVVNDTKNDSIGILLCGTGIGMNIAA
SKVHGTRVALVYNESSAKLAKEHNNANIITIGARENSLNQILKMIDDFLTSKFLGERHQKRLDIIAKYEKEQNS
>Mature_154_residues
MIKKIYFGNDHAAYEIKDQIITHLKQKGYQIIDEGAQAALGSVDYSTYALKVANDVVNDTKNDSIGILLCGTGIGMNIAA
SKVHGTRVALVYNESSAKLAKEHNNANIITIGARENSLNQILKMIDDFLTSKFLGERHQKRLDIIAKYEKEQNS

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=152, Percent_Identity=36.1842105263158, Blast_Score=111, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011860
- InterPro:   IPR003500 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 17056; Mature: 17056

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKIYFGNDHAAYEIKDQIITHLKQKGYQIIDEGAQAALGSVDYSTYALKVANDVVNDT
CCEEEEECCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHEEEEHHHHHHCCC
KNDSIGILLCGTGIGMNIAASKVHGTRVALVYNESSAKLAKEHNNANIITIGARENSLNQ
CCCCEEEEEECCCCCCCEEEEECCCEEEEEEEECCCHHHHHHCCCCCEEEEECCCCHHHH
ILKMIDDFLTSKFLGERHQKRLDIIAKYEKEQNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIKKIYFGNDHAAYEIKDQIITHLKQKGYQIIDEGAQAALGSVDYSTYALKVANDVVNDT
CCEEEEECCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHEEEEHHHHHHCCC
KNDSIGILLCGTGIGMNIAASKVHGTRVALVYNESSAKLAKEHNNANIITIGARENSLNQ
CCCCEEEEEECCCCCCCEEEEECCCEEEEEEEECCCHHHHHHCCCCCEEEEECCCCHHHH
ILKMIDDFLTSKFLGERHQKRLDIIAKYEKEQNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA