Click here to switch to the map view.

The map label for this gene is pgcA [H]

Identifier: 15595180

GI number: 15595180

Start: 886470

End: 888182

Strand: Reverse

Name: pgcA [H]

Synonym: BB0835

Alternate gene names: 15595180

Gene position: 888182-886470 (Counterclockwise)

Preceding gene: 15595184

Following gene: 15595179

Centisome position: 97.52

GC content: 27.38

Gene sequence:

>1713_bases
TTGATGCTAAAAATCGAAGCTAAAAGAAAATTGAAAAATTATATTCTTCTTGAAGAAGATATGCATTTTAAAGAAGAAGC
AATAAAAATTCAAAAAACAAATAATTCAACAGAAATTTTAAATAGATTTTACAAAGATCTAGAATTTGGCACTGCTGGAA
TAAGGGGAATCATTGGAGCTGGAACATGTTACATGAACACATATAATATAAAAAAAATAAGCCAAGGAATATGCAATTAC
ATACTTAAAATAAACAAAAACCCTAAAGTTGCAATAAGCTATGATTCAAGATATTTTTCAAAAGAATTTGCTTACAATGC
TGCTCAAATTTTTGCCTCAAATAATTTTGAAACATATATATATAAAAGTTTAAGACCTTCCCCACAACTATCTTATACAA
TAAGAAAATTTGACTGTGATGCTGGCGTTATGATAACAGCAAGTCATAATTCAAAAGAATATAATGGATATAAAGCATAT
TGGAAAGGTGGAATCCAAATAATACCACCTCATGACACACTAATAACTAATGAAATTAAAAATACAAAAAACATAATAAA
TACAATTACCATAAAAGAAGGCATTGAAAAAGGGATCATCAAAGAACTTGGCAATGAAATAGACGAAGAGTATGTGAAAG
CAATAAACAAAGAATTGCCTGATTTTGAAAAGAATAGCAAAGAAACAAACTTAAAAATAGCCTACACAGCATTACATGGC
ACCGGTGGGACCATAATAAAAAAACTCTTTGCAAATAGCAAAATACGGCTTTTTTTAGAAAAAAATCAAATACTACCAAA
CCCTGAATTTCCAACAATAAATTATCCTAATCCAGAAAAACAAACATCAATGCTTAAAGTAATAGAGCTTGCAAAAAAAA
AAGATTGTGACATTGCCCTTGCAACAGATCCAGATGCCGACAGAATAGGGATTGCATTTAAAGATCAAAACGAATGGATA
TTCTTAAACGGAAATCAAATATCATGCATTTTAATGAACTATATACTCTCAAAAGAAAAAAATCCTAAAAATACATTTGT
AATATCATCGTTTGTAACAACACCAATGCTAGAAAAAATTGCAAAAAAATATGGTTCTCAAATTTTTAGAACTTACACAG
GATTTAAATGGATAGGAAGCTTAATTAATGAAATGGAAAAAAATGAACCAAATAAAAAATTTGCTTTTGCATGCGAAGAA
AGTCATGGATATCTAATAGGAAGAAAGGTTAGAGATAAGGATGCATTTTCAGCCATAAAAGGAATTTGTTCTTTAGCACT
TGACTTAAAAGCCAAACAACAAACAATTAAGGATTATCTTGAAAAGATATACAAAGAATTTGGATATTATGAAGAATTTA
ATATAGAAAAAAACTTTGAGGGGGCCAATGGAGAAATTCAAAGAGAAAAGTTAATGCTAAAACTAAGAAAAGAACAAAAA
GTACAATTTGCAGGAATTAAAATAATTGAAAAATTAGACTATAAAACTCTTAAAAAGATTAACTTTAAAAATGAAATTTC
AGAAATTAAAGAATATAAATACCCCATAAACGCAATAAAATTTATACTTGAAAACGAAATTGCAATAATTGTAAGACCCT
CTGGAACAGAGCCGAAAATTAAATTTTACATATCTGTAAAACTAGAGTATAAGGAAAAACATAAAATATTTGATATAATA
AATGCAATAAAGATGGAGATAAAAAAATATTAA

Upstream 100 bases:

>100_bases
TCTTATAAATTATATGATAATAAATTCTATATCAAGTATATAATTCATTATAAATCAATATAATTTAATTAATCTTTGTT
TAATAAAATAAAAGGAAATA

Downstream 100 bases:

>100_bases
CATAACAGAAAATTTAATAAATTTGGTAGAAATAGACTCAAAAGAAATTGCAAGAAAAAATAAAAATAAAGAGGTTTCAA
TTTGGCACTTATTAATGTCT

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MMLKIEAKRKLKNYILLEEDMHFKEEAIKIQKTNNSTEILNRFYKDLEFGTAGIRGIIGAGTCYMNTYNIKKISQGICNY
ILKINKNPKVAISYDSRYFSKEFAYNAAQIFASNNFETYIYKSLRPSPQLSYTIRKFDCDAGVMITASHNSKEYNGYKAY
WKGGIQIIPPHDTLITNEIKNTKNIINTITIKEGIEKGIIKELGNEIDEEYVKAINKELPDFEKNSKETNLKIAYTALHG
TGGTIIKKLFANSKIRLFLEKNQILPNPEFPTINYPNPEKQTSMLKVIELAKKKDCDIALATDPDADRIGIAFKDQNEWI
FLNGNQISCILMNYILSKEKNPKNTFVISSFVTTPMLEKIAKKYGSQIFRTYTGFKWIGSLINEMEKNEPNKKFAFACEE
SHGYLIGRKVRDKDAFSAIKGICSLALDLKAKQQTIKDYLEKIYKEFGYYEEFNIEKNFEGANGEIQREKLMLKLRKEQK
VQFAGIKIIEKLDYKTLKKINFKNEISEIKEYKYPINAIKFILENEIAIIVRPSGTEPKIKFYISVKLEYKEKHKIFDII
NAIKMEIKKY

Sequences:

>Translated_570_residues
MMLKIEAKRKLKNYILLEEDMHFKEEAIKIQKTNNSTEILNRFYKDLEFGTAGIRGIIGAGTCYMNTYNIKKISQGICNY
ILKINKNPKVAISYDSRYFSKEFAYNAAQIFASNNFETYIYKSLRPSPQLSYTIRKFDCDAGVMITASHNSKEYNGYKAY
WKGGIQIIPPHDTLITNEIKNTKNIINTITIKEGIEKGIIKELGNEIDEEYVKAINKELPDFEKNSKETNLKIAYTALHG
TGGTIIKKLFANSKIRLFLEKNQILPNPEFPTINYPNPEKQTSMLKVIELAKKKDCDIALATDPDADRIGIAFKDQNEWI
FLNGNQISCILMNYILSKEKNPKNTFVISSFVTTPMLEKIAKKYGSQIFRTYTGFKWIGSLINEMEKNEPNKKFAFACEE
SHGYLIGRKVRDKDAFSAIKGICSLALDLKAKQQTIKDYLEKIYKEFGYYEEFNIEKNFEGANGEIQREKLMLKLRKEQK
VQFAGIKIIEKLDYKTLKKINFKNEISEIKEYKYPINAIKFILENEIAIIVRPSGTEPKIKFYISVKLEYKEKHKIFDII
NAIKMEIKKY
>Mature_570_residues
MMLKIEAKRKLKNYILLEEDMHFKEEAIKIQKTNNSTEILNRFYKDLEFGTAGIRGIIGAGTCYMNTYNIKKISQGICNY
ILKINKNPKVAISYDSRYFSKEFAYNAAQIFASNNFETYIYKSLRPSPQLSYTIRKFDCDAGVMITASHNSKEYNGYKAY
WKGGIQIIPPHDTLITNEIKNTKNIINTITIKEGIEKGIIKELGNEIDEEYVKAINKELPDFEKNSKETNLKIAYTALHG
TGGTIIKKLFANSKIRLFLEKNQILPNPEFPTINYPNPEKQTSMLKVIELAKKKDCDIALATDPDADRIGIAFKDQNEWI
FLNGNQISCILMNYILSKEKNPKNTFVISSFVTTPMLEKIAKKYGSQIFRTYTGFKWIGSLINEMEKNEPNKKFAFACEE
SHGYLIGRKVRDKDAFSAIKGICSLALDLKAKQQTIKDYLEKIYKEFGYYEEFNIEKNFEGANGEIQREKLMLKLRKEQK
VQFAGIKIIEKLDYKTLKKINFKNEISEIKEYKYPINAIKFILENEIAIIVRPSGTEPKIKFYISVKLEYKEKHKIFDII
NAIKMEIKKY

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=546, Percent_Identity=32.6007326007326, Blast_Score=240, Evalue=3e-63,
Organism=Homo sapiens, GI31377548, Length=563, Percent_Identity=30.7282415630551, Blast_Score=232, Evalue=7e-61,
Organism=Escherichia coli, GI1786904, Length=436, Percent_Identity=22.2477064220184, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71993870, Length=555, Percent_Identity=30.4504504504505, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI71993878, Length=312, Percent_Identity=34.2948717948718, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6323934, Length=568, Percent_Identity=30.9859154929577, Blast_Score=214, Evalue=4e-56,
Organism=Drosophila melanogaster, GI20129809, Length=560, Percent_Identity=31.0714285714286, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI24651977, Length=428, Percent_Identity=34.3457943925234, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24653722, Length=463, Percent_Identity=28.2937365010799, Blast_Score=221, Evalue=8e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 66009; Mature: 66009

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLKIEAKRKLKNYILLEEDMHFKEEAIKIQKTNNSTEILNRFYKDLEFGTAGIRGIIGA
CEEEEEHHHHHHHEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHEEEC
GTCYMNTYNIKKISQGICNYILKINKNPKVAISYDSRYFSKEFAYNAAQIFASNNFETYI
CEEEEEECCHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHCCCEEEEECCCCCEEE
YKSLRPSPQLSYTIRKFDCDAGVMITASHNSKEYNGYKAYWKGGIQIIPPHDTLITNEIK
EECCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCEEHHHHH
NTKNIINTITIKEGIEKGIIKELGNEIDEEYVKAINKELPDFEKNSKETNLKIAYTALHG
HHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEC
TGGTIIKKLFANSKIRLFLEKNQILPNPEFPTINYPNPEKQTSMLKVIELAKKKDCDIAL
CCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEE
ATDPDADRIGIAFKDQNEWIFLNGNQISCILMNYILSKEKNPKNTFVISSFVTTPMLEKI
ECCCCCCEEEEEEECCCCEEEEECCEEEHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHH
AKKYGSQIFRTYTGFKWIGSLINEMEKNEPNKKFAFACEESHGYLIGRKVRDKDAFSAIK
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCHHHHHHHH
GICSLALDLKAKQQTIKDYLEKIYKEFGYYEEFNIEKNFEGANGEIQREKLMLKLRKEQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHC
VQFAGIKIIEKLDYKTLKKINFKNEISEIKEYKYPINAIKFILENEIAIIVRPSGTEPKI
HHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCCCEE
KFYISVKLEYKEKHKIFDIINAIKMEIKKY
EEEEEEEEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMLKIEAKRKLKNYILLEEDMHFKEEAIKIQKTNNSTEILNRFYKDLEFGTAGIRGIIGA
CEEEEEHHHHHHHEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHEEEC
GTCYMNTYNIKKISQGICNYILKINKNPKVAISYDSRYFSKEFAYNAAQIFASNNFETYI
CEEEEEECCHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHCCCEEEEECCCCCEEE
YKSLRPSPQLSYTIRKFDCDAGVMITASHNSKEYNGYKAYWKGGIQIIPPHDTLITNEIK
EECCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCEEHHHHH
NTKNIINTITIKEGIEKGIIKELGNEIDEEYVKAINKELPDFEKNSKETNLKIAYTALHG
HHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEC
TGGTIIKKLFANSKIRLFLEKNQILPNPEFPTINYPNPEKQTSMLKVIELAKKKDCDIAL
CCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEE
ATDPDADRIGIAFKDQNEWIFLNGNQISCILMNYILSKEKNPKNTFVISSFVTTPMLEKI
ECCCCCCEEEEEEECCCCEEEEECCEEEHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHH
AKKYGSQIFRTYTGFKWIGSLINEMEKNEPNKKFAFACEESHGYLIGRKVRDKDAFSAIK
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCHHHHHHHH
GICSLALDLKAKQQTIKDYLEKIYKEFGYYEEFNIEKNFEGANGEIQREKLMLKLRKEQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHC
VQFAGIKIIEKLDYKTLKKINFKNEISEIKEYKYPINAIKFILENEIAIIVRPSGTEPKI
HHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCCCCEE
KFYISVKLEYKEKHKIFDIINAIKMEIKKY
EEEEEEEEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]