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The map label for this gene is clpB [H]

Identifier: 15595179

GI number: 15595179

Start: 884228

End: 886447

Strand: Reverse

Name: clpB [H]

Synonym: BB0834

Alternate gene names: 15595179

Gene position: 886447-884228 (Counterclockwise)

Preceding gene: 15595180

Following gene: 15595178

Centisome position: 97.33

GC content: 27.07

Gene sequence:

>2220_bases
TTGGTAGAAATAGACTCAAAAGAAATTGCAAGAAAAAATAAAAATAAAGAGGTTTCAATTTGGCACTTATTAATGTCTAT
AATTACCACTCCCAAAAAATCCGAAATAAAATTTATAGATAGCAAAACTCTAAAAAACATTAAACAAGAAGTTATATCTG
AAATAGATAAATTAGAGAAAATTTTAATAGAAAAAAACGAAATAATTATTCCCAAAATCAATAAAGAAATCTTTGCTCTC
ATAAAAGAAGCTAAAAAGGAATTTAAATCCAAACCTTTAATAGGGGCAAAAGAAATTTTTTATCAAATATTAAAAAATAA
AAAACTTCTTAAAAAACATAAACTAAGTAAATCTAGCTTTAACTTTAAAGATCAAAATATATTAGAATACATGGAAAAAA
ATAAAATAAGATTAATTGAAACCTACAAAGAATTTGATGAAGAAATACGACTTGAAAATGAGCACTTTGAAATTGGAAAG
TATGTCAAAAATTTAACAGCACTTGCAAAAGCCAAAAAATTAGACCCCTTGGTTGGAAGAGAAGCAGAGATTAAAACTCT
TACAAATATACTCTTGAGAAGAAATAAAAATAGTGCAATGCTAATAGGCGAACCTGGTGTGGGAAAAACAGCAATAGTTG
AAGGCCTTGCATCAAGCATAGTGCAAAAAAAAATAAGTAGCAAACTACAAGACAAAACAATTCTAATGCTTAAGGTTTCA
AACTTGGTATCGGGAACAAAATATAGAGGCGAGTTTGAAGATCGTTTAAATAATATAATTAAGTATATTGAAAAAAACAA
AAACACAATCATATTTATTGACGAAATACACACTCTAATAGGAGCTGGAAACTCTGAAGGAGCTCTTGATGCATCAAATA
TACTAAAACCATCACTTTCTAGAGCTGAAATACAAATTATTGGCGCAACTACTTACAATGAATATCGAAAATATATTTCA
AAAGACAAAGCATTCGCCAGAAGATTCCAAACAATTACCGTAAAAGAGCCTGATGAAAAAGATACACTAAAAATAATCGA
AAATATTGCAAAAAATTTTGAAGACTATCATGGAGTGATCTATGAAAAAAGCGCGCTTTTAAATATAGTAAAACTTTCAT
CCAAATATCTAATAAATAAAAGATTTCCAGATAAAGCAATAGATATAATAGACATTGCCGGCGCAATTAAAAAGGAAGAA
CTTACAAAAGACAACATCATAACATCAGATGATATACAAAAGGCAATAAATGAAATATTATCTATTAAAACAGCAAATAA
CACTAAAGAAGAAATTTTAGAATTAAAAGAAATAGAAAGCGAAATAAATAAAAAGGTGATCGGACAAAAACATGCGGTAA
GCGAACTTATCAAAGAAATTATTAAAGTCAAACTTGGACTTAATGACGATTCTAAGCCTTTAACTTCAATATTGTTAATA
GGATCAAGTGGATGTGGAAAAACTGCTTTAACTGATGAAATATCTAAAAAAATTATCAAAGATCAAAATTCAGTATTAAA
ACTAGATATGTCAGACTATAAAGAAGAAAACTCTATTTCAAAATTAATTGGCACAAATCCAGGATACGTAGGCTACTCTG
ATGGAGGCATTCTGACAAATAAATTAAGACATTCATTTGAAACTTTAATATTGTTTGAAAATATTGAAAATGCCCACAGC
TCTGTATTAAACCTAATAAGTCGAATGCTTGAAAACGGAGAACTTATTGACAGCAAAGAAGATAAAATACTATTTAAAAA
CACAATTATAATAATGACTACAAACATTGGATCTAGAATGCTTCTTGGAGAAAAAAATATTGGATTCAACAAAAATCAAC
AAAAAAGCTTAGAAACAAAAAGCTTTAAAGAAGAAATAAACCAAGATCTTGAAAAAAGATTTAAATTATCCTTTTTAGAC
AGAATTCAAAAAAAAATCATCCTAAATATCCTTACAAAGGAAAATGTAGAAGAAATTTGCAAAAACTACTTAAACACCCT
TAAAACAAAATTTCACTCTAAAGGAATCGAGATAGAAATAAAAAAAGATGTTGACAAATTCATAACCACAAAATACTATA
AAAAAAATTCAGGAGCAAGAAGCGTAATTGCTGCAATAAAGGGGAAAATAGAAGAAAATATTATCACCAAAATAGCTGAA
AATCAAAACATAAATAAAATAACGATTTATTTAGAAAAAGAAAAAATAATAATAGAATAA

Upstream 100 bases:

>100_bases
GTAAAACTAGAGTATAAGGAAAAACATAAAATATTTGATATAATAAATGCAATAAAGATGGAGATAAAAAAATATTAACA
TAACAGAAAATTTAATAAAT

Downstream 100 bases:

>100_bases
AGAGGAATTATAATATGTTTAAAAAAGTAGAAAACAAGGCAAATTTTCCTAAAATAGAAGAAAAAATATTAAAATTTTGG
AATGACAATAAGATCTTTGA

Product: ATP-dependent Clp protease subunit C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 739; Mature: 739

Protein sequence:

>739_residues
MVEIDSKEIARKNKNKEVSIWHLLMSIITTPKKSEIKFIDSKTLKNIKQEVISEIDKLEKILIEKNEIIIPKINKEIFAL
IKEAKKEFKSKPLIGAKEIFYQILKNKKLLKKHKLSKSSFNFKDQNILEYMEKNKIRLIETYKEFDEEIRLENEHFEIGK
YVKNLTALAKAKKLDPLVGREAEIKTLTNILLRRNKNSAMLIGEPGVGKTAIVEGLASSIVQKKISSKLQDKTILMLKVS
NLVSGTKYRGEFEDRLNNIIKYIEKNKNTIIFIDEIHTLIGAGNSEGALDASNILKPSLSRAEIQIIGATTYNEYRKYIS
KDKAFARRFQTITVKEPDEKDTLKIIENIAKNFEDYHGVIYEKSALLNIVKLSSKYLINKRFPDKAIDIIDIAGAIKKEE
LTKDNIITSDDIQKAINEILSIKTANNTKEEILELKEIESEINKKVIGQKHAVSELIKEIIKVKLGLNDDSKPLTSILLI
GSSGCGKTALTDEISKKIIKDQNSVLKLDMSDYKEENSISKLIGTNPGYVGYSDGGILTNKLRHSFETLILFENIENAHS
SVLNLISRMLENGELIDSKEDKILFKNTIIIMTTNIGSRMLLGEKNIGFNKNQQKSLETKSFKEEINQDLEKRFKLSFLD
RIQKKIILNILTKENVEEICKNYLNTLKTKFHSKGIEIEIKKDVDKFITTKYYKKNSGARSVIAAIKGKIEENIITKIAE
NQNINKITIYLEKEKIIIE

Sequences:

>Translated_739_residues
MVEIDSKEIARKNKNKEVSIWHLLMSIITTPKKSEIKFIDSKTLKNIKQEVISEIDKLEKILIEKNEIIIPKINKEIFAL
IKEAKKEFKSKPLIGAKEIFYQILKNKKLLKKHKLSKSSFNFKDQNILEYMEKNKIRLIETYKEFDEEIRLENEHFEIGK
YVKNLTALAKAKKLDPLVGREAEIKTLTNILLRRNKNSAMLIGEPGVGKTAIVEGLASSIVQKKISSKLQDKTILMLKVS
NLVSGTKYRGEFEDRLNNIIKYIEKNKNTIIFIDEIHTLIGAGNSEGALDASNILKPSLSRAEIQIIGATTYNEYRKYIS
KDKAFARRFQTITVKEPDEKDTLKIIENIAKNFEDYHGVIYEKSALLNIVKLSSKYLINKRFPDKAIDIIDIAGAIKKEE
LTKDNIITSDDIQKAINEILSIKTANNTKEEILELKEIESEINKKVIGQKHAVSELIKEIIKVKLGLNDDSKPLTSILLI
GSSGCGKTALTDEISKKIIKDQNSVLKLDMSDYKEENSISKLIGTNPGYVGYSDGGILTNKLRHSFETLILFENIENAHS
SVLNLISRMLENGELIDSKEDKILFKNTIIIMTTNIGSRMLLGEKNIGFNKNQQKSLETKSFKEEINQDLEKRFKLSFLD
RIQKKIILNILTKENVEEICKNYLNTLKTKFHSKGIEIEIKKDVDKFITTKYYKKNSGARSVIAAIKGKIEENIITKIAE
NQNINKITIYLEKEKIIIE
>Mature_739_residues
MVEIDSKEIARKNKNKEVSIWHLLMSIITTPKKSEIKFIDSKTLKNIKQEVISEIDKLEKILIEKNEIIIPKINKEIFAL
IKEAKKEFKSKPLIGAKEIFYQILKNKKLLKKHKLSKSSFNFKDQNILEYMEKNKIRLIETYKEFDEEIRLENEHFEIGK
YVKNLTALAKAKKLDPLVGREAEIKTLTNILLRRNKNSAMLIGEPGVGKTAIVEGLASSIVQKKISSKLQDKTILMLKVS
NLVSGTKYRGEFEDRLNNIIKYIEKNKNTIIFIDEIHTLIGAGNSEGALDASNILKPSLSRAEIQIIGATTYNEYRKYIS
KDKAFARRFQTITVKEPDEKDTLKIIENIAKNFEDYHGVIYEKSALLNIVKLSSKYLINKRFPDKAIDIIDIAGAIKKEE
LTKDNIITSDDIQKAINEILSIKTANNTKEEILELKEIESEINKKVIGQKHAVSELIKEIIKVKLGLNDDSKPLTSILLI
GSSGCGKTALTDEISKKIIKDQNSVLKLDMSDYKEENSISKLIGTNPGYVGYSDGGILTNKLRHSFETLILFENIENAHS
SVLNLISRMLENGELIDSKEDKILFKNTIIIMTTNIGSRMLLGEKNIGFNKNQQKSLETKSFKEEINQDLEKRFKLSFLD
RIQKKIILNILTKENVEEICKNYLNTLKTKFHSKGIEIEIKKDVDKFITTKYYKKNSGARSVIAAIKGKIEENIITKIAE
NQNINKITIYLEKEKIIIE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=162, Percent_Identity=36.4197530864198, Blast_Score=119, Evalue=9e-27,
Organism=Escherichia coli, GI1787109, Length=749, Percent_Identity=31.5086782376502, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1788943, Length=245, Percent_Identity=46.1224489795918, Blast_Score=245, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6323002, Length=402, Percent_Identity=34.3283582089552, Blast_Score=230, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6320464, Length=284, Percent_Identity=41.9014084507042, Blast_Score=225, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 84444; Mature: 84444

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEIDSKEIARKNKNKEVSIWHLLMSIITTPKKSEIKFIDSKTLKNIKQEVISEIDKLEK
CCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
ILIEKNEIIIPKINKEIFALIKEAKKEFKSKPLIGAKEIFYQILKNKKLLKKHKLSKSSF
HHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHCCCCCC
NFKDQNILEYMEKNKIRLIETYKEFDEEIRLENEHFEIGKYVKNLTALAKAKKLDPLVGR
CCCHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
EAEIKTLTNILLRRNKNSAMLIGEPGVGKTAIVEGLASSIVQKKISSKLQDKTILMLKVS
CHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
NLVSGTKYRGEFEDRLNNIIKYIEKNKNTIIFIDEIHTLIGAGNSEGALDASNILKPSLS
HHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCCCCHHHHCCCCCC
RAEIQIIGATTYNEYRKYISKDKAFARRFQTITVKEPDEKDTLKIIENIAKNFEDYHGVI
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
YEKSALLNIVKLSSKYLINKRFPDKAIDIIDIAGAIKKEELTKDNIITSDDIQKAINEIL
EEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SIKTANNTKEEILELKEIESEINKKVIGQKHAVSELIKEIIKVKLGLNDDSKPLTSILLI
HHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
GSSGCGKTALTDEISKKIIKDQNSVLKLDMSDYKEENSISKLIGTNPGYVGYSDGGILTN
ECCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHCCCHHHHHHHHCCCCCEEEECCCCCHHH
KLRHSFETLILFENIENAHSSVLNLISRMLENGELIDSKEDKILFKNTIIIMTTNIGSRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCCCEE
LLGEKNIGFNKNQQKSLETKSFKEEINQDLEKRFKLSFLDRIQKKIILNILTKENVEEIC
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KNYLNTLKTKFHSKGIEIEIKKDVDKFITTKYYKKNSGARSVIAAIKGKIEENIITKIAE
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
NQNINKITIYLEKEKIIIE
CCCCCEEEEEEECCEEEEC
>Mature Secondary Structure
MVEIDSKEIARKNKNKEVSIWHLLMSIITTPKKSEIKFIDSKTLKNIKQEVISEIDKLEK
CCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
ILIEKNEIIIPKINKEIFALIKEAKKEFKSKPLIGAKEIFYQILKNKKLLKKHKLSKSSF
HHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHCCCCCC
NFKDQNILEYMEKNKIRLIETYKEFDEEIRLENEHFEIGKYVKNLTALAKAKKLDPLVGR
CCCHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
EAEIKTLTNILLRRNKNSAMLIGEPGVGKTAIVEGLASSIVQKKISSKLQDKTILMLKVS
CHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEH
NLVSGTKYRGEFEDRLNNIIKYIEKNKNTIIFIDEIHTLIGAGNSEGALDASNILKPSLS
HHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCCCCHHHHCCCCCC
RAEIQIIGATTYNEYRKYISKDKAFARRFQTITVKEPDEKDTLKIIENIAKNFEDYHGVI
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
YEKSALLNIVKLSSKYLINKRFPDKAIDIIDIAGAIKKEELTKDNIITSDDIQKAINEIL
EEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SIKTANNTKEEILELKEIESEINKKVIGQKHAVSELIKEIIKVKLGLNDDSKPLTSILLI
HHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
GSSGCGKTALTDEISKKIIKDQNSVLKLDMSDYKEENSISKLIGTNPGYVGYSDGGILTN
ECCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHCCCHHHHHHHHCCCCCEEEECCCCCHHH
KLRHSFETLILFENIENAHSSVLNLISRMLENGELIDSKEDKILFKNTIIIMTTNIGSRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCCCEE
LLGEKNIGFNKNQQKSLETKSFKEEINQDLEKRFKLSFLDRIQKKIILNILTKENVEEIC
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KNYLNTLKTKFHSKGIEIEIKKDVDKFITTKYYKKNSGARSVIAAIKGKIEENIITKIAE
HHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
NQNINKITIYLEKEKIIIE
CCCCCEEEEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]