Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 15595114

GI number: 15595114

Start: 810470

End: 811510

Strand: Reverse

Name: gcp [H]

Synonym: BB0769

Alternate gene names: 15595114

Gene position: 811510-810470 (Counterclockwise)

Preceding gene: 15595115

Following gene: 15595113

Centisome position: 89.11

GC content: 32.28

Gene sequence:

>1041_bases
ATGAAAGTGCTTGGAATAGAAACCTCTTGTGACGACTGTTGCGTAGCTGTAGTAGAAAATGGAATTCATATTTTAAGCAA
TATAAAATTAAATCAAACCGAACACAAAAAATATTACGGCATAGTGCCTGAGATTGCCTCAAGACTTCATACGGAAGCTA
TTATGTCTGTTTGTATAAAAGCACTAAAAAAGGCAAATACTAAAATATCTGAAATTGACTTAATAGCTGTAACATCTAGA
CCTGGACTTATTGGATCTTTAATAGTTGGATTAAACTTTGCCAAAGGTCTAGCAATTTCATTAAAAAAGCCCATTATTTG
CATTGATCACATCTTGGGTCATCTTTACGCCCCTTTAATGCACTCAAAAATAGAATATCCATTTATATCATTATTATTAA
GTGGTGGACATACATTGATTGCTAAACAAAAAAATTTCGATGATGTTGAAATACTTGGAAGAACTCTAGATGATGCTTGT
GGAGAGGCTTTTGATAAAGTGGCAAAACATTATGATATGGGATTTCCGGGAGGTCCAAACATCGAACAAATATCTAAAAA
TGGAGATGAAAATACATTTCAATTTCCAGTTACCACCTTTAAAAAAAAAGAAAACTGGTATGATTTTTCATACTCTGGAC
TAAAAACAGCTTGCATACACCAACTCGAAAAATTCAAAAGCAAAGATAACCCAACAACAAAAAATAATATAGCTGCAAGC
TTCCAAAAAGCTGCCTTTGAAAATCTAATCACCCCACTAAAAAGGGCAATAAAAGATACTCAAATCAACAAATTGGTAAT
AGCAGGAGGTGTTGCAAGCAATTTATATTTAAGAGAAAAAATAGATAAGCTTAAAATACAAACTTACTACCCTCCTCTTG
ACCTTTGCACAGACAATGGAGCAATGATTGCGGGACTTGGATTTAATATGTATTTAAAATATGGAGAAAGTCCAATTGAA
ATTGATGCAAATTCAAGAATAGAAAATTATAAAAACCAGTATAGGGGGAAAAATAATGAAAAGAATTTTAGCAATGCATG
A

Upstream 100 bases:

>100_bases
GGTCTAAAAATACGCTAAAAGTCCTTAAAAAAGAAGGACCTGATTTAAACCAGGAATTCGAATTCGACAACTTATTAAAT
CTTTACGAGGAAACAATCAG

Downstream 100 bases:

>100_bases
TATTTCAAGCATGGGAAGAACATCTCTTACAATATGCATACCAGTAATATCTTCGTTTAATATGCAAGTTTGTCCTTTTG
TGACAGCTGTCCTTTCTGCT

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKVLGIETSCDDCCVAVVENGIHILSNIKLNQTEHKKYYGIVPEIASRLHTEAIMSVCIKALKKANTKISEIDLIAVTSR
PGLIGSLIVGLNFAKGLAISLKKPIICIDHILGHLYAPLMHSKIEYPFISLLLSGGHTLIAKQKNFDDVEILGRTLDDAC
GEAFDKVAKHYDMGFPGGPNIEQISKNGDENTFQFPVTTFKKKENWYDFSYSGLKTACIHQLEKFKSKDNPTTKNNIAAS
FQKAAFENLITPLKRAIKDTQINKLVIAGGVASNLYLREKIDKLKIQTYYPPLDLCTDNGAMIAGLGFNMYLKYGESPIE
IDANSRIENYKNQYRGKNNEKNFSNA

Sequences:

>Translated_346_residues
MKVLGIETSCDDCCVAVVENGIHILSNIKLNQTEHKKYYGIVPEIASRLHTEAIMSVCIKALKKANTKISEIDLIAVTSR
PGLIGSLIVGLNFAKGLAISLKKPIICIDHILGHLYAPLMHSKIEYPFISLLLSGGHTLIAKQKNFDDVEILGRTLDDAC
GEAFDKVAKHYDMGFPGGPNIEQISKNGDENTFQFPVTTFKKKENWYDFSYSGLKTACIHQLEKFKSKDNPTTKNNIAAS
FQKAAFENLITPLKRAIKDTQINKLVIAGGVASNLYLREKIDKLKIQTYYPPLDLCTDNGAMIAGLGFNMYLKYGESPIE
IDANSRIENYKNQYRGKNNEKNFSNA
>Mature_346_residues
MKVLGIETSCDDCCVAVVENGIHILSNIKLNQTEHKKYYGIVPEIASRLHTEAIMSVCIKALKKANTKISEIDLIAVTSR
PGLIGSLIVGLNFAKGLAISLKKPIICIDHILGHLYAPLMHSKIEYPFISLLLSGGHTLIAKQKNFDDVEILGRTLDDAC
GEAFDKVAKHYDMGFPGGPNIEQISKNGDENTFQFPVTTFKKKENWYDFSYSGLKTACIHQLEKFKSKDNPTTKNNIAAS
FQKAAFENLITPLKRAIKDTQINKLVIAGGVASNLYLREKIDKLKIQTYYPPLDLCTDNGAMIAGLGFNMYLKYGESPIE
IDANSRIENYKNQYRGKNNEKNFSNA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=332, Percent_Identity=37.3493975903614, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI8923380, Length=324, Percent_Identity=27.1604938271605, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1789445, Length=314, Percent_Identity=38.2165605095541, Blast_Score=226, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17557464, Length=337, Percent_Identity=30.8605341246291, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71995670, Length=318, Percent_Identity=30.8176100628931, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=346, Percent_Identity=36.1271676300578, Blast_Score=180, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322891, Length=301, Percent_Identity=27.906976744186, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20129063, Length=355, Percent_Identity=32.6760563380282, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=26.1261261261261, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 38487; Mature: 38487

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLGIETSCDDCCVAVVENGIHILSNIKLNQTEHKKYYGIVPEIASRLHTEAIMSVCIK
CEEEECCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
ALKKANTKISEIDLIAVTSRPGLIGSLIVGLNFAKGLAISLKKPIICIDHILGHLYAPLM
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHH
HSKIEYPFISLLLSGGHTLIAKQKNFDDVEILGRTLDDACGEAFDKVAKHYDMGFPGGPN
HCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IEQISKNGDENTFQFPVTTFKKKENWYDFSYSGLKTACIHQLEKFKSKDNPTTKNNIAAS
HHHHHCCCCCCEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
FQKAAFENLITPLKRAIKDTQINKLVIAGGVASNLYLREKIDKLKIQTYYPPLDLCTDNG
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHEEEEEECCCHHEECCCC
AMIAGLGFNMYLKYGESPIEIDANSRIENYKNQYRGKNNEKNFSNA
CEEEECCEEEEEEECCCCEEECCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKVLGIETSCDDCCVAVVENGIHILSNIKLNQTEHKKYYGIVPEIASRLHTEAIMSVCIK
CEEEECCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
ALKKANTKISEIDLIAVTSRPGLIGSLIVGLNFAKGLAISLKKPIICIDHILGHLYAPLM
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHH
HSKIEYPFISLLLSGGHTLIAKQKNFDDVEILGRTLDDACGEAFDKVAKHYDMGFPGGPN
HCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IEQISKNGDENTFQFPVTTFKKKENWYDFSYSGLKTACIHQLEKFKSKDNPTTKNNIAAS
HHHHHCCCCCCEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
FQKAAFENLITPLKRAIKDTQINKLVIAGGVASNLYLREKIDKLKIQTYYPPLDLCTDNG
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHEEEEEECCCHHEECCCC
AMIAGLGFNMYLKYGESPIEIDANSRIENYKNQYRGKNNEKNFSNA
CEEEECCEEEEEEECCCCEEECCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA