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The map label for this gene is atoC [H]

Identifier: 15595108

GI number: 15595108

Start: 804417

End: 805778

Strand: Reverse

Name: atoC [H]

Synonym: BB0763

Alternate gene names: 15595108

Gene position: 805778-804417 (Counterclockwise)

Preceding gene: 15595109

Following gene: 15595107

Centisome position: 88.48

GC content: 29.39

Gene sequence:

>1362_bases
TTGAAAATGAGCAAAATACTTGTAGCTGATGATGAAAAGAATATTAGAGAAGGAATTGCTACTTATCTTGAGGATGAAGG
ATATTTTGTTTTCACTGCTAGTGACGGAGAAGAAGCTCTTGAAACAATTGAAAATGAAAATCTTGATGTAATAATATCTG
ACCTGAGAATGCCCCAGATATCTGGAGAAAAATTGCTCAAAATAGTTAAAGAAAAAAACTTGGGAATACCTTTTATTATT
CTAACAGCCCACGGAACAGTTGATTCTGCTGTAGATGCCATGAGAGAGGGTGCTTATGATTTTTTAACAAAGCCCTTAGA
CCTTGAAAGACTTTTGCTAATAATAAAAAGATCACTAAATAAAAAAGAAAATAACGATAATGAAAATGCTAATTTAGAAA
ATATACTAATAAGAAAAGATCTAAAATACTATGAAAAAATCATGGGAAAATCCCTATTAATGCAAAAAATTTTTGAACTT
GTAATAAAAATAGCAAAATCAAATGCATCTATTCTTATAACGGGCGAAAGCGGTGTTGGTAAAGAAATAATAGCAGATGC
TATTTTTGATCTTTCAAATAGAAATGACAAACCATTTATAAAAGTAAATTGCGCAGCACTTTCTGAAAGCATTCTTGAAA
GTGAACTTTTTGGCCATGAAAAAGGAGCATTCACTGGAGCAATTTCCAAAAAAAAAGGCAGATTTGAACTTGCAAACAAA
GGCACAATTTTTCTTGATGAGATAGCAGAAATTTCACCTGAAATTCAAGTCAAGCTTTTAAGAGTACTGCAAAACAAAAC
TTTTGAACGTGTTGGGGGAGAAGCTACAATTAAAGTTGATATCAGGCTTCTGGCTGCAACAAACAAAAACATTGAAGAGG
AAATTAAAAAGGAAAAATTTAGAGAAGATTTATTTTATAGATTAAATATCATTAATATAAACATACCGCCTTTAAGAGAA
AGAAAAGATGATATATCTTATTTAACAAACATACTAATAAAAGACGTCGCAAAGGAAAACAATAGAGAAGAAAAAACTCT
TTCTAATGATGCAATGAAAGCTCTCTATTATTACGATTGGCCAGGAAATATTAGAGAATTAAAAAATGTGCTTGAAAGTG
CATTAATATTATCAAAAGGCAAACAAATCACTAAAGAAGATTTGCCAGCAAAAATCAAAAATAATGAAAATCTTATATTT
AAAATAACACTACCAATNGGAATTAGCCTAAAAGAAGCTGAAAAAGAAATAATAAAACAAACACTTTTTCATTCCAAAAA
CAACAAAAGCAAATGCGCCGAAATACTAAAAATAGGAAGAAAAACTTTACACAATAAAATAATCGAATATAATATTGATT
AA

Upstream 100 bases:

>100_bases
TTGGAGGTGAAATTTTTGTGGAAAGCAAAGAGGGCAAAGGCACTATTTTTACAATTACGCTGCCTAAACTAAATAAAAAA
AATATTTTAATTGAAGGGTA

Downstream 100 bases:

>100_bases
TAGGATTTATTTTAAATTATTAAATTATAATGGGTACAAAAAAATAATACTGCTTTAAATTCCATGTATATTTTTGAAAC
CAAAAAATTTTTTAATGCCA

Product: response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKMSKILVADDEKNIREGIATYLEDEGYFVFTASDGEEALETIENENLDVIISDLRMPQISGEKLLKIVKEKNLGIPFII
LTAHGTVDSAVDAMREGAYDFLTKPLDLERLLLIIKRSLNKKENNDNENANLENILIRKDLKYYEKIMGKSLLMQKIFEL
VIKIAKSNASILITGESGVGKEIIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISKKKGRFELANK
GTIFLDEIAEISPEIQVKLLRVLQNKTFERVGGEATIKVDIRLLAATNKNIEEEIKKEKFREDLFYRLNIININIPPLRE
RKDDISYLTNILIKDVAKENNREEKTLSNDAMKALYYYDWPGNIRELKNVLESALILSKGKQITKEDLPAKIKNNENLIF
KITLPXGISLKEAEKEIIKQTLFHSKNNKSKCAEILKIGRKTLHNKIIEYNID

Sequences:

>Translated_453_residues
MKMSKILVADDEKNIREGIATYLEDEGYFVFTASDGEEALETIENENLDVIISDLRMPQISGEKLLKIVKEKNLGIPFII
LTAHGTVDSAVDAMREGAYDFLTKPLDLERLLLIIKRSLNKKENNDNENANLENILIRKDLKYYEKIMGKSLLMQKIFEL
VIKIAKSNASILITGESGVGKEIIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISKKKGRFELANK
GTIFLDEIAEISPEIQVKLLRVLQNKTFERVGGEATIKVDIRLLAATNKNIEEEIKKEKFREDLFYRLNIININIPPLRE
RKDDISYLTNILIKDVAKENNREEKTLSNDAMKALYYYDWPGNIRELKNVLESALILSKGKQITKEDLPAKIKNNENLIF
KITLPXGISLKEAEKEIIKQTLFHSKNNKSKCAEILKIGRKTLHNKIIEYNID
>Mature_453_residues
MKMSKILVADDEKNIREGIATYLEDEGYFVFTASDGEEALETIENENLDVIISDLRMPQISGEKLLKIVKEKNLGIPFII
LTAHGTVDSAVDAMREGAYDFLTKPLDLERLLLIIKRSLNKKENNDNENANLENILIRKDLKYYEKIMGKSLLMQKIFEL
VIKIAKSNASILITGESGVGKEIIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISKKKGRFELANK
GTIFLDEIAEISPEIQVKLLRVLQNKTFERVGGEATIKVDIRLLAATNKNIEEEIKKEKFREDLFYRLNIININIPPLRE
RKDDISYLTNILIKDVAKENNREEKTLSNDAMKALYYYDWPGNIRELKNVLESALILSKGKQITKEDLPAKIKNNENLIF
KITLPXGISLKEAEKEIIKQTLFHSKNNKSKCAEILKIGRKTLHNKIIEYNID

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=457, Percent_Identity=44.2013129102845, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1790437, Length=447, Percent_Identity=40.9395973154362, Blast_Score=350, Evalue=7e-98,
Organism=Escherichia coli, GI1790299, Length=484, Percent_Identity=35.7438016528926, Blast_Score=344, Evalue=7e-96,
Organism=Escherichia coli, GI1788905, Length=383, Percent_Identity=40.7310704960835, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI87082117, Length=237, Percent_Identity=48.9451476793249, Blast_Score=264, Evalue=8e-72,
Organism=Escherichia coli, GI1789087, Length=237, Percent_Identity=45.5696202531646, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1789233, Length=326, Percent_Identity=39.5705521472393, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI87082152, Length=313, Percent_Identity=39.6166134185303, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787583, Length=332, Percent_Identity=37.0481927710843, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1786524, Length=248, Percent_Identity=43.9516129032258, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87081872, Length=309, Percent_Identity=38.1877022653722, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=30.3754266211604, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789828, Length=239, Percent_Identity=33.0543933054393, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786784, Length=117, Percent_Identity=29.9145299145299, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790552, Length=209, Percent_Identity=24.8803827751196, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789402, Length=132, Percent_Identity=31.0606060606061, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=115, Percent_Identity=31.304347826087, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=31.9327731092437, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51473; Mature: 51473

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMSKILVADDEKNIREGIATYLEDEGYFVFTASDGEEALETIENENLDVIISDLRMPQI
CCCCEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCC
SGEKLLKIVKEKNLGIPFIILTAHGTVDSAVDAMREGAYDFLTKPLDLERLLLIIKRSLN
CHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHC
KKENNDNENANLENILIRKDLKYYEKIMGKSLLMQKIFELVIKIAKSNASILITGESGVG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
KEIIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISKKKGRFELANK
HHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEECCC
GTIFLDEIAEISPEIQVKLLRVLQNKTFERVGGEATIKVDIRLLAATNKNIEEEIKKEKF
CCEEEHHHHHCCHHHHHHHHHHHHHCHHHHCCCCEEEEEEEEEEEECCCCHHHHHHHHHH
REDLFYRLNIININIPPLRERKDDISYLTNILIKDVAKENNREEKTLSNDAMKALYYYDW
HHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECC
PGNIRELKNVLESALILSKGKQITKEDLPAKIKNNENLIFKITLPXGISLKEAEKEIIKQ
CCCHHHHHHHHHHHHHHHCCCCCCHHCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHHH
TLFHSKNNKSKCAEILKIGRKTLHNKIIEYNID
HHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MKMSKILVADDEKNIREGIATYLEDEGYFVFTASDGEEALETIENENLDVIISDLRMPQI
CCCCEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCCCCC
SGEKLLKIVKEKNLGIPFIILTAHGTVDSAVDAMREGAYDFLTKPLDLERLLLIIKRSLN
CHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHC
KKENNDNENANLENILIRKDLKYYEKIMGKSLLMQKIFELVIKIAKSNASILITGESGVG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
KEIIADAIFDLSNRNDKPFIKVNCAALSESILESELFGHEKGAFTGAISKKKGRFELANK
HHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEECCC
GTIFLDEIAEISPEIQVKLLRVLQNKTFERVGGEATIKVDIRLLAATNKNIEEEIKKEKF
CCEEEHHHHHCCHHHHHHHHHHHHHCHHHHCCCCEEEEEEEEEEEECCCCHHHHHHHHHH
REDLFYRLNIININIPPLRERKDDISYLTNILIKDVAKENNREEKTLSNDAMKALYYYDW
HHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEECC
PGNIRELKNVLESALILSKGKQITKEDLPAKIKNNENLIFKITLPXGISLKEAEKEIIKQ
CCCHHHHHHHHHHHHHHHCCCCCCHHCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHHH
TLFHSKNNKSKCAEILKIGRKTLHNKIIEYNID
HHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]