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The map label for this gene is gph [H]

Identifier: 15595021

GI number: 15595021

Start: 714104

End: 714766

Strand: Reverse

Name: gph [H]

Synonym: BB0676

Alternate gene names: 15595021

Gene position: 714766-714104 (Counterclockwise)

Preceding gene: 15595027

Following gene: 15595020

Centisome position: 78.48

GC content: 30.47

Gene sequence:

>663_bases
ATGAAAATCAAAGCCTGCATTTTTGATATGGATGGAACACTGGTAAATAGTATAATGGATATTGCATTCTCAATGAATTC
TGCTCTTTCAAACTTAGGATACAGTAAAATAGAACTAAGCAAATTCAATGCCCTTGTTGGCAGAGGATTTAACAAGTTTG
TAATAGACACTCTAAAGCTATTATCTCTTGAACATGATAATCCTAATTTACAAGAAAAACTTTACAAAGAATTTGTTAAA
GAATACAATAAAAACCTTTCATTCCAAACAAAACCATATGAAAATATAAAACCCCTTTTAGAAACTATGAATAAGCTTAA
CATTCCAATTGGAATTTTAAGCAATAAGAACCACGAAGAATTAATAAATTTGGTGAAAAATATTTTTGGAAATATATTGT
TTTTTGAAATCAGGGGTTATTCAAAAAATTTTCCACCAAAGCCAGATCCTGAAAATGCCCTTGATATGATATTAGAATTA
AATGCCCAAAAAGAAGAAATTGCATATATTGGAGACAGCGATGTGGATATGCTAACCGCACTAAACGCTGGATTTATGCC
AATAGGGGTTTCTTGGGGATTTAGAAGTGTTCAAGAATTAAAAGAAAGTGGAGCAAAACATATAATACACAATCCACTTG
AACTATTGGACCTAATAAAATGA

Upstream 100 bases:

>100_bases
TGCTAATAAATAAAAATGCTTAAAATATAAAAACCTTAATAAAGAGAGCAAATTAATGTTAAAATAAAAGAATAAATAAA
TTATTACAAAAGAGAGTATT

Downstream 100 bases:

>100_bases
ATACAAAACCATATTTTCCTTATTTATATCATTATCTATTCAATCATGAAAGTATAAAAAGTTTATCTGCCATAGAAAAA
GAAATTGAAATACTCAACTA

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKIKACIFDMDGTLVNSIMDIAFSMNSALSNLGYSKIELSKFNALVGRGFNKFVIDTLKLLSLEHDNPNLQEKLYKEFVK
EYNKNLSFQTKPYENIKPLLETMNKLNIPIGILSNKNHEELINLVKNIFGNILFFEIRGYSKNFPPKPDPENALDMILEL
NAQKEEIAYIGDSDVDMLTALNAGFMPIGVSWGFRSVQELKESGAKHIIHNPLELLDLIK

Sequences:

>Translated_220_residues
MKIKACIFDMDGTLVNSIMDIAFSMNSALSNLGYSKIELSKFNALVGRGFNKFVIDTLKLLSLEHDNPNLQEKLYKEFVK
EYNKNLSFQTKPYENIKPLLETMNKLNIPIGILSNKNHEELINLVKNIFGNILFFEIRGYSKNFPPKPDPENALDMILEL
NAQKEEIAYIGDSDVDMLTALNAGFMPIGVSWGFRSVQELKESGAKHIIHNPLELLDLIK
>Mature_220_residues
MKIKACIFDMDGTLVNSIMDIAFSMNSALSNLGYSKIELSKFNALVGRGFNKFVIDTLKLLSLEHDNPNLQEKLYKEFVK
EYNKNLSFQTKPYENIKPLLETMNKLNIPIGILSNKNHEELINLVKNIFGNILFFEIRGYSKNFPPKPDPENALDMILEL
NAQKEEIAYIGDSDVDMLTALNAGFMPIGVSWGFRSVQELKESGAKHIIHNPLELLDLIK

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24984; Mature: 24984

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKACIFDMDGTLVNSIMDIAFSMNSALSNLGYSKIELSKFNALVGRGFNKFVIDTLKL
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LSLEHDNPNLQEKLYKEFVKEYNKNLSFQTKPYENIKPLLETMNKLNIPIGILSNKNHEE
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHH
LINLVKNIFGNILFFEIRGYSKNFPPKPDPENALDMILELNAQKEEIAYIGDSDVDMLTA
HHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHEEEECCCCHHHHHH
LNAGFMPIGVSWGFRSVQELKESGAKHIIHNPLELLDLIK
HCCCCEEEECCCCHHHHHHHHHCCCHHHHCCHHHHHHHCC
>Mature Secondary Structure
MKIKACIFDMDGTLVNSIMDIAFSMNSALSNLGYSKIELSKFNALVGRGFNKFVIDTLKL
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
LSLEHDNPNLQEKLYKEFVKEYNKNLSFQTKPYENIKPLLETMNKLNIPIGILSNKNHEE
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHH
LINLVKNIFGNILFFEIRGYSKNFPPKPDPENALDMILELNAQKEEIAYIGDSDVDMLTA
HHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHEEEECCCCHHHHHH
LNAGFMPIGVSWGFRSVQELKESGAKHIIHNPLELLDLIK
HCCCCEEEECCCCHHHHHHHHHCCCHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]