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The map label for this gene is argS

Identifier: 15594939

GI number: 15594939

Start: 614014

End: 615789

Strand: Reverse

Name: argS

Synonym: BB0594

Alternate gene names: 15594939

Gene position: 615789-614014 (Counterclockwise)

Preceding gene: 15594940

Following gene: 15594936

Centisome position: 67.62

GC content: 28.55

Gene sequence:

>1776_bases
GTGTTAAAGAGGAAAAAAATGAATAAAAGTGTTAAAAAAAAGATTAAAGACGAAATTAATGTTATAGTTACTAATCTAGC
ATTATCAAATAACATAAAGCTAGATAATATCAATATAAATATTCAAAAACCTCCAAAAAGTGATCTGGGAGATATTTCCA
TATTAATGTTTGAAATTGGTAAAACCTTAAAACTCCCTATTGAAATCATCTCCGAAGAAATAATAAAAAATCTTAAAACT
AAATATGAAATTAAAGCTGTGGGGCCTTACTTAAACATCAAAATTTCTAGAAAAGAATATATAAATAATACAATACAAAT
GGTAAATACTCAAAAAGATACCTATGGAACAAGTAAATATCTAGACAATAAAAAAATAATATTAGAATTTTCATCACCAA
ATACAAACAAACCACTGCATGTAGGACATCTTAGAAATGACGTAATAGGAGAAAGTCTGTCAAGAATATTAAAGGCTGTG
GGTGCAAAAATTACAAAAATAAACTTAATAAATGACCGAGGGGTTCATATCTGCAAATCAATGCTTGCATACAAAAAATT
TGGAAATGGCATTACCCCTGAAAAAGCTTTTAAAAAAGGAGATCATTTAATTGGCGATTTTTATGTTAAATACAACAAAT
ACTCACAAGAAAATGAAAATGCTGAAAAAGAAATTCAAGATCTACTTTTACTCTGGGAGCAAAAAGATGTAAGCACAATT
GAACTTTGGAAAAAGTTAAATAAATGGGCAATTGAAGGAATAAAAGAAACATACGAAATTACAAACACCTCATTTGATAA
AATTTACCTTGAAAGTGAAATTTTTAAAATTGGAAAAAATGTCGTATTAGAAGGGCTTGAAAAAGGATTTTGTTACAAAC
GAGAAGATGGCGCAATATGCATTGACTTACCTTCAGACTCAGATGAAAAAGCAGACACCAAGGTAAAACAAAAAGTACTC
ATAAGATCAAACGGAACATCTATCTATCTTACCCAAGATTTAGGAAATATAGCAGTTAGAACAAAAGAATTTAATTTTGA
AGAAATGATTTATGTGGTTGGAAGCGAACAAATTCAGCACTTCAAAAGCTTGTTTTTTGTAGCAGAAAAATTAGGCCTTT
CTAAAAACAAGAAACTTATTCATTTGTCACACGGAATGGTTAATCTTGTTGATGGAAAAATGAAATCAAGAGAAGGCAAT
GTAATTGATGCGGATAACCTAATCTCAAACTTAATAGAATTAATAATACCTGAAATGACACAAAAAATTGAAAATAAAGA
GAGCGCTAAAAAAAATGCTTTAAATATTGCATTGGGAGCAATTCACTATTATCTGCTAAAATCAGCTATACATAAAGATA
TTGTATTTAATAAAAAAGAAAGCCTGTCTTTTACGGGAAATTCTGGACCATATATCCAATATGTTGGAGCAAGAATTAAT
AGCATTCTTGAAAAATATAAAGCACTTTCTATTCCTGTAATGGAAAAAATTGACTTTGAACTTTTAAAACATGAAAAAGA
GTGGGAAATTATTAAAATTATATCGGAATTAGAAGAAAATATAATCAATGCGGCAAAAGATTTAAACCCTTCAATACTTA
CCAGCTATTCATACTCGCTTGCAAAGCATTTTAGCACGTACTATCAAGAAGTTAAAGTAATAGATACAAACAATATCAAT
TTAACAGCCGCAAGAATCGAATTTTTAAAAGCCATATTACAAACAATAAAAAATTGCATGTACCTGCTCAATATTCCCTA
TATGTTAAAAATGTAG

Upstream 100 bases:

>100_bases
AAAATGTCGGCCCATAGCTCAAACATTTTTATTGTAGCGTCTTTATTTTTACTATTAATCAATATGCTAACAAAAATTAA
AGAGAAAAAAATGAATAAAA

Downstream 100 bases:

>100_bases
GCAAGAAAATTTTACAAAATTTTCTTGCCTAATATCCGTTTAAATCTAAGTCACTTTTGCTAAAAATTAATTTTATTTTA
TCTTCATACTTTTTGGATAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MLKRKKMNKSVKKKIKDEINVIVTNLALSNNIKLDNININIQKPPKSDLGDISILMFEIGKTLKLPIEIISEEIIKNLKT
KYEIKAVGPYLNIKISRKEYINNTIQMVNTQKDTYGTSKYLDNKKIILEFSSPNTNKPLHVGHLRNDVIGESLSRILKAV
GAKITKINLINDRGVHICKSMLAYKKFGNGITPEKAFKKGDHLIGDFYVKYNKYSQENENAEKEIQDLLLLWEQKDVSTI
ELWKKLNKWAIEGIKETYEITNTSFDKIYLESEIFKIGKNVVLEGLEKGFCYKREDGAICIDLPSDSDEKADTKVKQKVL
IRSNGTSIYLTQDLGNIAVRTKEFNFEEMIYVVGSEQIQHFKSLFFVAEKLGLSKNKKLIHLSHGMVNLVDGKMKSREGN
VIDADNLISNLIELIIPEMTQKIENKESAKKNALNIALGAIHYYLLKSAIHKDIVFNKKESLSFTGNSGPYIQYVGARIN
SILEKYKALSIPVMEKIDFELLKHEKEWEIIKIISELEENIINAAKDLNPSILTSYSYSLAKHFSTYYQEVKVIDTNNIN
LTAARIEFLKAILQTIKNCMYLLNIPYMLKM

Sequences:

>Translated_591_residues
MLKRKKMNKSVKKKIKDEINVIVTNLALSNNIKLDNININIQKPPKSDLGDISILMFEIGKTLKLPIEIISEEIIKNLKT
KYEIKAVGPYLNIKISRKEYINNTIQMVNTQKDTYGTSKYLDNKKIILEFSSPNTNKPLHVGHLRNDVIGESLSRILKAV
GAKITKINLINDRGVHICKSMLAYKKFGNGITPEKAFKKGDHLIGDFYVKYNKYSQENENAEKEIQDLLLLWEQKDVSTI
ELWKKLNKWAIEGIKETYEITNTSFDKIYLESEIFKIGKNVVLEGLEKGFCYKREDGAICIDLPSDSDEKADTKVKQKVL
IRSNGTSIYLTQDLGNIAVRTKEFNFEEMIYVVGSEQIQHFKSLFFVAEKLGLSKNKKLIHLSHGMVNLVDGKMKSREGN
VIDADNLISNLIELIIPEMTQKIENKESAKKNALNIALGAIHYYLLKSAIHKDIVFNKKESLSFTGNSGPYIQYVGARIN
SILEKYKALSIPVMEKIDFELLKHEKEWEIIKIISELEENIINAAKDLNPSILTSYSYSLAKHFSTYYQEVKVIDTNNIN
LTAARIEFLKAILQTIKNCMYLLNIPYMLKM
>Mature_591_residues
MLKRKKMNKSVKKKIKDEINVIVTNLALSNNIKLDNININIQKPPKSDLGDISILMFEIGKTLKLPIEIISEEIIKNLKT
KYEIKAVGPYLNIKISRKEYINNTIQMVNTQKDTYGTSKYLDNKKIILEFSSPNTNKPLHVGHLRNDVIGESLSRILKAV
GAKITKINLINDRGVHICKSMLAYKKFGNGITPEKAFKKGDHLIGDFYVKYNKYSQENENAEKEIQDLLLLWEQKDVSTI
ELWKKLNKWAIEGIKETYEITNTSFDKIYLESEIFKIGKNVVLEGLEKGFCYKREDGAICIDLPSDSDEKADTKVKQKVL
IRSNGTSIYLTQDLGNIAVRTKEFNFEEMIYVVGSEQIQHFKSLFFVAEKLGLSKNKKLIHLSHGMVNLVDGKMKSREGN
VIDADNLISNLIELIIPEMTQKIENKESAKKNALNIALGAIHYYLLKSAIHKDIVFNKKESLSFTGNSGPYIQYVGARIN
SILEKYKALSIPVMEKIDFELLKHEKEWEIIKIISELEENIINAAKDLNPSILTSYSYSLAKHFSTYYQEVKVIDTNNIN
LTAARIEFLKAILQTIKNCMYLLNIPYMLKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=589, Percent_Identity=24.7877758913413, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI15149476, Length=514, Percent_Identity=27.0428015564202, Blast_Score=141, Evalue=2e-33,
Organism=Escherichia coli, GI1788184, Length=573, Percent_Identity=22.5130890052356, Blast_Score=146, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17532153, Length=487, Percent_Identity=23.6139630390144, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71985061, Length=462, Percent_Identity=25.974025974026, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985068, Length=462, Percent_Identity=25.974025974026, Blast_Score=117, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320548, Length=523, Percent_Identity=28.1070745697897, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6321883, Length=513, Percent_Identity=28.0701754385965, Blast_Score=210, Evalue=5e-55,
Organism=Drosophila melanogaster, GI18859963, Length=487, Percent_Identity=24.6406570841889, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28571570, Length=480, Percent_Identity=22.7083333333333, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_BORBU (O51540)

Other databases:

- EMBL:   AE000783
- PIR:   A70174
- RefSeq:   NP_212728.1
- ProteinModelPortal:   O51540
- SMR:   O51540
- EnsemblBacteria:   EBBORT00000008531
- GeneID:   1195441
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0594
- NMPDR:   fig|224326.1.peg.978
- TIGR:   BB_0594
- GeneTree:   EBGT00050000006845
- HOGENOM:   HBG695395
- OMA:   YNDDLQP
- PhylomeDB:   O51540
- ProtClustDB:   PRK01611
- BioCyc:   BBUR224326:BB_0594-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 67638; Mature: 67638

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRKKMNKSVKKKIKDEINVIVTNLALSNNIKLDNININIQKPPKSDLGDISILMFEIG
CCCHHHHHHHHHHHHHHHHHEEEEEEEECCCEEEEEEEEEEECCCCCCCCCCEEEEEHHC
KTLKLPIEIISEEIIKNLKTKYEIKAVGPYLNIKISRKEYINNTIQMVNTQKDTYGTSKY
CCCCCHHHHHHHHHHHHCCCCEEEEEECCEEEEEECHHHHHCHHHHHHCCCCCCCCCHHH
LDNKKIILEFSSPNTNKPLHVGHLRNDVIGESLSRILKAVGAKITKINLINDRGVHICKS
CCCCEEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHH
MLAYKKFGNGITPEKAFKKGDHLIGDFYVKYNKYSQENENAEKEIQDLLLLWEQKDVSTI
HHHHHHHCCCCCHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHH
ELWKKLNKWAIEGIKETYEITNTSFDKIYLESEIFKIGKNVVLEGLEKGFCYKREDGAIC
HHHHHHHHHHHHHHHHHHHHCCCCHHHEEEHHHHHHHHHHHHHHHHHCCCCEEECCCEEE
IDLPSDSDEKADTKVKQKVLIRSNGTSIYLTQDLGNIAVRTKEFNFEEMIYVVGSEQIQH
EECCCCCCCHHHHHHHHEEEEEECCCEEEEEECCCCEEEEEECCCHHHEEEEECHHHHHH
FKSLFFVAEKLGLSKNKKLIHLSHGMVNLVDGKMKSREGNVIDADNLISNLIELIIPEMT
HHHHHHHHHHHCCCCCCCEEEECCCEEEECCCCCCCCCCCEECHHHHHHHHHHHHHHHHH
QKIENKESAKKNALNIALGAIHYYLLKSAIHKDIVFNKKESLSFTGNSGPYIQYVGARIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEHHHHHH
SILEKYKALSIPVMEKIDFELLKHEKEWEIIKIISELEENIINAAKDLNPSILTSYSYSL
HHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AKHFSTYYQEVKVIDTNNINLTAARIEFLKAILQTIKNCMYLLNIPYMLKM
HHHHHHHHHEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
>Mature Secondary Structure
MLKRKKMNKSVKKKIKDEINVIVTNLALSNNIKLDNININIQKPPKSDLGDISILMFEIG
CCCHHHHHHHHHHHHHHHHHEEEEEEEECCCEEEEEEEEEEECCCCCCCCCCEEEEEHHC
KTLKLPIEIISEEIIKNLKTKYEIKAVGPYLNIKISRKEYINNTIQMVNTQKDTYGTSKY
CCCCCHHHHHHHHHHHHCCCCEEEEEECCEEEEEECHHHHHCHHHHHHCCCCCCCCCHHH
LDNKKIILEFSSPNTNKPLHVGHLRNDVIGESLSRILKAVGAKITKINLINDRGVHICKS
CCCCEEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHH
MLAYKKFGNGITPEKAFKKGDHLIGDFYVKYNKYSQENENAEKEIQDLLLLWEQKDVSTI
HHHHHHHCCCCCHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHH
ELWKKLNKWAIEGIKETYEITNTSFDKIYLESEIFKIGKNVVLEGLEKGFCYKREDGAIC
HHHHHHHHHHHHHHHHHHHHCCCCHHHEEEHHHHHHHHHHHHHHHHHCCCCEEECCCEEE
IDLPSDSDEKADTKVKQKVLIRSNGTSIYLTQDLGNIAVRTKEFNFEEMIYVVGSEQIQH
EECCCCCCCHHHHHHHHEEEEEECCCEEEEEECCCCEEEEEECCCHHHEEEEECHHHHHH
FKSLFFVAEKLGLSKNKKLIHLSHGMVNLVDGKMKSREGNVIDADNLISNLIELIIPEMT
HHHHHHHHHHHCCCCCCCEEEECCCEEEECCCCCCCCCCCEECHHHHHHHHHHHHHHHHH
QKIENKESAKKNALNIALGAIHYYLLKSAIHKDIVFNKKESLSFTGNSGPYIQYVGARIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEHHHHHH
SILEKYKALSIPVMEKIDFELLKHEKEWEIIKIISELEENIINAAKDLNPSILTSYSYSL
HHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AKHFSTYYQEVKVIDTNNINLTAARIEFLKAILQTIKNCMYLLNIPYMLKM
HHHHHHHHHEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685