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The map label for this gene is pyrH [H]

Identifier: 15594916

GI number: 15594916

Start: 584191

End: 584880

Strand: Reverse

Name: pyrH [H]

Synonym: BB0571

Alternate gene names: 15594916

Gene position: 584880-584191 (Counterclockwise)

Preceding gene: 15594921

Following gene: 15594909

Centisome position: 64.22

GC content: 26.67

Gene sequence:

>690_bases
ATGCTTGAAATAATAAGTCTTGGAGGAGGAGTAATAAATTCAAACCAAATCAACATAGAATTCATTAAAAACTTTAAAAA
CTTTGTTTTTAAATGGCTACTAGAAAATGAAAAAAGAAAAATCATTTTAATAGTTGGTGGAGGAAGAGTTGCAAGAGAAT
ACCAAGATGCTTATAAAAAAATCAATCCTGATTTTAAAGTTCATGAACTTGATGAGATTGGAATAATATCAACAAGACTA
AACGCAGAATTTCTGAGTAAAGTAATGAATCCCTTTTGTAAAGACAAAATTGTCACTAATCCCTTAAAAAATTTTTCTTT
TAAAGGAAAAATATTAATTGCTTCCGGATGGAAATCAGGATTCTCAACAGATTACATTGCCGTAAAATTTGCAGAAAAAT
TTAATAAAAAAGATATCATAAATATAACAAACGTAAATCAAGTTTATGATAAAGACCCAAAAAAATTTAAAAACGCAACA
GCTTTTAAAAAATTAAATTGGAAACAATTACAAAACATTGTGGGCCAAAAGTGGAATCCAGGCTTAAATTTACCTTTTGA
CCCAATAGCAACAAAACTCTCTTCAAAACTTGGACTTACCCTTTACATAGTAAATGGAAATAATATTGAAAACTTAGAAA
AAGTTTTTAACAAAAATAATGATTTTTTTGGCACTATTATAGTAAAATAA

Upstream 100 bases:

>100_bases
TGTATTGTTTCAAACTTATTTTAATGAAAAGTTTAGCAGAAATTGCTATATTATTAAAAGTAAAAAATTTAAAAAACATC
AACCCAAATAAGGAGCTTGA

Downstream 100 bases:

>100_bases
AAGTTAATGCCGGTATGGCGGAATTGGTAGACGCGCCAGACTCAAAATCTGGTGAGGGCAACTTCATGTCGGTTCGACTC
CGACTACCGGTATTTTGATT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGRVAREYQDAYKKINPDFKVHELDEIGIISTRL
NAEFLSKVMNPFCKDKIVTNPLKNFSFKGKILIASGWKSGFSTDYIAVKFAEKFNKKDIINITNVNQVYDKDPKKFKNAT
AFKKLNWKQLQNIVGQKWNPGLNLPFDPIATKLSSKLGLTLYIVNGNNIENLEKVFNKNNDFFGTIIVK

Sequences:

>Translated_229_residues
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGRVAREYQDAYKKINPDFKVHELDEIGIISTRL
NAEFLSKVMNPFCKDKIVTNPLKNFSFKGKILIASGWKSGFSTDYIAVKFAEKFNKKDIINITNVNQVYDKDPKKFKNAT
AFKKLNWKQLQNIVGQKWNPGLNLPFDPIATKLSSKLGLTLYIVNGNNIENLEKVFNKNNDFFGTIIVK
>Mature_229_residues
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGRVAREYQDAYKKINPDFKVHELDEIGIISTRL
NAEFLSKVMNPFCKDKIVTNPLKNFSFKGKILIASGWKSGFSTDYIAVKFAEKFNKKDIINITNVNQVYDKDPKKFKNAT
AFKKLNWKQLQNIVGQKWNPGLNLPFDPIATKLSSKLGLTLYIVNGNNIENLEKVFNKNNDFFGTIIVK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR011818 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26213; Mature: 26213

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGRVAREYQDAYKK
CEEEEECCCCEECCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHH
INPDFKVHELDEIGIISTRLNAEFLSKVMNPFCKDKIVTNPLKNFSFKGKILIASGWKSG
CCCCCEEEECCCCCEEEECCCHHHHHHHHCHHHHHHHHCCHHHCCCCCCEEEEEECCCCC
FSTDYIAVKFAEKFNKKDIINITNVNQVYDKDPKKFKNATAFKKLNWKQLQNIVGQKWNP
CCCCEEEEEEHHHCCCCCEEEECCCHHHHCCCHHHHHCHHHHHCCCHHHHHHHHCCCCCC
GLNLPFDPIATKLSSKLGLTLYIVNGNNIENLEKVFNKNNDFFGTIIVK
CCCCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGRVAREYQDAYKK
CEEEEECCCCEECCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHH
INPDFKVHELDEIGIISTRLNAEFLSKVMNPFCKDKIVTNPLKNFSFKGKILIASGWKSG
CCCCCEEEECCCCCEEEECCCHHHHHHHHCHHHHHHHHCCHHHCCCCCCEEEEEECCCCC
FSTDYIAVKFAEKFNKKDIINITNVNQVYDKDPKKFKNATAFKKLNWKQLQNIVGQKWNP
CCCCEEEEEEHHHCCCCCEEEECCCHHHHCCCHHHHHCHHHHHCCCHHHHHHHHCCCCCC
GLNLPFDPIATKLSSKLGLTLYIVNGNNIENLEKVFNKNNDFFGTIIVK
CCCCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11029001 [H]