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The map label for this gene is ftsW

Identifier: 15594647

GI number: 15594647

Start: 310559

End: 311653

Strand: Reverse

Name: ftsW

Synonym: BB0302

Alternate gene names: 15594647

Gene position: 311653-310559 (Counterclockwise)

Preceding gene: 15594648

Following gene: 15594646

Centisome position: 34.22

GC content: 29.13

Gene sequence:

>1095_bases
ATGGTTGTAGAGATAAATTCACTTAGGACATGTTATTTGCTTGTTTTGCTGCTATTGGTAGCCTATGGCCTTGTAGTTTT
TTATACTTCTTCCTTTTTTCTAAGCTTAGAATTGACAGGTAATCCAAATTTTTTATTTTTCACAAGACTTAATTATCTTT
TTTTAAGTTTTATGGTTTTTCTTGTTTTTGAAAGGATTTCTTTAAATTTTTTAAAAAAATCAATATTTCCTGTATTGATT
ATAACTCTTTTTTTAATTATGGCAACTTTTTTATCTCCAAGTATTTCTGGAGCAAAGAGATGGATATTCTTTCAAGGTGT
TAGCATTCAACCTTCTGAGATTTTTAAAATATCTTTTACTATTTATCTTTCAGCTTATTTGAGCAAGTTTGACCCAAGAA
AAAACAATGGTATTTCATACTGGATAAAGCCAATGTTGATTTTTGCAATTTTTTGGGTGTTAATAATTTTGCAAAACGAT
TATTCAACAGCTATTTATTTTGCCATTCTTTTTTTTATTGTTTTGTTTGTTTCTAATATGGCATTTAGCTATGTTTTTGC
TATTGTGGTTACTTTTTTACCAGTTTCTGCTATATTCTTGATGCTTGAACCTTATAGGGTTTCTAGAATTTTTGCCTTTC
TCAATCCTTACGATGATCCTTCTGGCAAAGGTTACCAGATAATAGCATCTCTTAATGCTTTAAAAAGTGGAGGAATTTTA
GGTAAAGGGCTGGGAATGGGAGAGGTAAAACTTGGAAAATTACCAGAGGCCAATTCGGATTTTATTTTTTCAGTTCTTGG
AGAAGAATTAGGATTTTTAGGGGTTTTGTTTGCTATAAGCTTGTTTTTTTTGTTTTTTTACTTTGGTTATTTTATAGCTA
TTCATTCTAATAGTAGGTTTAAATTTTTTATTGCATTTATTTCAAGTCTTGCAATTTTTCTTCAAAGCATGATGAATATT
TTAATTGCAATCGGTCTTTTGCCTCCTACAGGGATAAATTTACCATTTTTTTCATCTGGGGGATCTTCTATTATTGTTAC
CATGGCATTGTCTGGCCTTATTTCAAATGTTTCAAAAAATTTAAGTAATAATTGA

Upstream 100 bases:

>100_bases
ACTTGGGTGGTCTGAAATGCAAGTTGTTATTAGATTTTGGATAATAGGGTTAATATTTGCTATAATTGCTTTAAGCACGA
TAAAAATCAGATAATTTATT

Downstream 100 bases:

>100_bases
TTAGATTTTTCTAGTAGTGTAAATTGAGTTAGGTTATGATTTTTGAGAGAAAATTTTTAATTAAGTATATATATTTCTTG
ACGTCTTTAATTTTTTTTGA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MVVEINSLRTCYLLVLLLLVAYGLVVFYTSSFFLSLELTGNPNFLFFTRLNYLFLSFMVFLVFERISLNFLKKSIFPVLI
ITLFLIMATFLSPSISGAKRWIFFQGVSIQPSEIFKISFTIYLSAYLSKFDPRKNNGISYWIKPMLIFAIFWVLIILQND
YSTAIYFAILFFIVLFVSNMAFSYVFAIVVTFLPVSAIFLMLEPYRVSRIFAFLNPYDDPSGKGYQIIASLNALKSGGIL
GKGLGMGEVKLGKLPEANSDFIFSVLGEELGFLGVLFAISLFFLFFYFGYFIAIHSNSRFKFFIAFISSLAIFLQSMMNI
LIAIGLLPPTGINLPFFSSGGSSIIVTMALSGLISNVSKNLSNN

Sequences:

>Translated_364_residues
MVVEINSLRTCYLLVLLLLVAYGLVVFYTSSFFLSLELTGNPNFLFFTRLNYLFLSFMVFLVFERISLNFLKKSIFPVLI
ITLFLIMATFLSPSISGAKRWIFFQGVSIQPSEIFKISFTIYLSAYLSKFDPRKNNGISYWIKPMLIFAIFWVLIILQND
YSTAIYFAILFFIVLFVSNMAFSYVFAIVVTFLPVSAIFLMLEPYRVSRIFAFLNPYDDPSGKGYQIIASLNALKSGGIL
GKGLGMGEVKLGKLPEANSDFIFSVLGEELGFLGVLFAISLFFLFFYFGYFIAIHSNSRFKFFIAFISSLAIFLQSMMNI
LIAIGLLPPTGINLPFFSSGGSSIIVTMALSGLISNVSKNLSNN
>Mature_364_residues
MVVEINSLRTCYLLVLLLLVAYGLVVFYTSSFFLSLELTGNPNFLFFTRLNYLFLSFMVFLVFERISLNFLKKSIFPVLI
ITLFLIMATFLSPSISGAKRWIFFQGVSIQPSEIFKISFTIYLSAYLSKFDPRKNNGISYWIKPMLIFAIFWVLIILQND
YSTAIYFAILFFIVLFVSNMAFSYVFAIVVTFLPVSAIFLMLEPYRVSRIFAFLNPYDDPSGKGYQIIASLNALKSGGIL
GKGLGMGEVKLGKLPEANSDFIFSVLGEELGFLGVLFAISLFFLFFYFGYFIAIHSNSRFKFFIAFISSLAIFLQSMMNI
LIAIGLLPPTGINLPFFSSGGSSIIVTMALSGLISNVSKNLSNN

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family

Homologues:

Organism=Escherichia coli, GI1786277, Length=334, Percent_Identity=32.3353293413174, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI1786853, Length=289, Percent_Identity=35.9861591695502, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSW_BORBU (Q44775)

Other databases:

- EMBL:   U43739
- EMBL:   X96685
- EMBL:   X96433
- EMBL:   AE000783
- PIR:   F70137
- RefSeq:   NP_212436.1
- EnsemblBacteria:   EBBORT00000008877
- GeneID:   1195139
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0302
- NMPDR:   fig|224326.1.peg.686
- TIGR:   BB_0302
- GeneTree:   EBGT00050000007207
- HOGENOM:   HBG729614
- OMA:   TIYLSAY
- PhylomeDB:   Q44775
- ProtClustDB:   CLSK232788
- BioCyc:   BBUR224326:BB_0302-MONOMER
- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- TIGRFAMs:   TIGR02614

Pfam domain/function: PF01098 FTSW_RODA_SPOVE

EC number: NA

Molecular weight: Translated: 40950; Mature: 40950

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00428 FTSW_RODA_SPOVE; PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbfec684)-; HASH(0xae64578)-; HASH(0xc3be7b0)-; HASH(0x972f15c)-; HASH(0xb796118)-; HASH(0xc040834)-; HASH(0xc6bde84)-; HASH(0xc70eb70)-; HASH(0xc0b2f44)-; HASH(0xc444a60)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVEINSLRTCYLLVLLLLVAYGLVVFYTSSFFLSLELTGNPNFLFFTRLNYLFLSFMVF
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEHHHHHHHHHHHHH
LVFERISLNFLKKSIFPVLIITLFLIMATFLSPSISGAKRWIFFQGVSIQPSEIFKISFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHEEEHHH
IYLSAYLSKFDPRKNNGISYWIKPMLIFAIFWVLIILQNDYSTAIYFAILFFIVLFVSNM
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AFSYVFAIVVTFLPVSAIFLMLEPYRVSRIFAFLNPYDDPSGKGYQIIASLNALKSGGIL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCCE
GKGLGMGEVKLGKLPEANSDFIFSVLGEELGFLGVLFAISLFFLFFYFGYFIAIHSNSRF
ECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCH
KFFIAFISSLAIFLQSMMNILIAIGLLPPTGINLPFFSSGGSSIIVTMALSGLISNVSKN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LSNN
CCCH
>Mature Secondary Structure
MVVEINSLRTCYLLVLLLLVAYGLVVFYTSSFFLSLELTGNPNFLFFTRLNYLFLSFMVF
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEHHHHHHHHHHHHH
LVFERISLNFLKKSIFPVLIITLFLIMATFLSPSISGAKRWIFFQGVSIQPSEIFKISFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHEEEHHH
IYLSAYLSKFDPRKNNGISYWIKPMLIFAIFWVLIILQNDYSTAIYFAILFFIVLFVSNM
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AFSYVFAIVVTFLPVSAIFLMLEPYRVSRIFAFLNPYDDPSGKGYQIIASLNALKSGGIL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCCE
GKGLGMGEVKLGKLPEANSDFIFSVLGEELGFLGVLFAISLFFLFFYFGYFIAIHSNSRF
ECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCH
KFFIAFISSLAIFLQSMMNILIAIGLLPPTGINLPFFSSGGSSIIVTMALSGLISNVSKN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LSNN
CCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9403685