Click here to switch to the map view.

The map label for this gene is lnt

Identifier: 15594582

GI number: 15594582

Start: 242438

End: 244003

Strand: Direct

Name: lnt

Synonym: BB0237

Alternate gene names: 15594582

Gene position: 242438-244003 (Clockwise)

Preceding gene: 15594573

Following gene: 15594585

Centisome position: 26.62

GC content: 30.78

Gene sequence:

>1566_bases
ATGAAAACTAGATGCTTTTGCTTAGCCGCATTTTCAGGAATTCTTACAACACTTGCAATTCCAAATGAAATTAAAGAAAC
CGGATATTCAATCCTTGGATTTGTTGCTTATGTACCACTTTTTATAGCCTTAAACAAACTAGAAGATAAAAAAGCATTAA
TGGGACTGACGGTATTTTACTTTATAATAGCCAACAGCCTGCAAAATTTTTGGCTTGGGTTTTTTCATGCATTTGGATGG
ATTACATTCATTGGAGTGATAATAGGGTACATTCCATATTCACTAACTTTAGGCTATTTCCTTTATTACTCTTTAAAAAG
CTTTAAAAATAAAACGATGAGCATAACAATGCTTTTTACATTTTATGATTACTCAAGATCAATTGGATTTTTAGCATATC
CTTGGGGGCTTGCAGCTTTCACCGTAAATAACTTCAACAATTTAATTCAAATAGCAGACATTTTTGGTGTATTTTTTGTA
TCATTTGCAGTCTACTTTTTAAACTCGGGAATTGCAGACTTTCTAATCCACAAAAACAAAACAAATTTGCTAAACATAGC
ATTTCCAACATTGCTAATAACAGCATCTTTTACTTACGGAATGATCAAAAAAATTGAGCTAAAAAACTTATTAGCAAAAG
AAATAGACAGTCTAAACATTGCAGCTATTCAGCTTAACACTGATCCATGGTTGCCAGGAAATGACAAAAAAGGAATAAGA
GACTCTATTGAAATTACAGAGCAAGCCTTAAAAGAAAATCCAAAAATAGAATTTGTAATCTGGAGCGAAGGGGTGCTAAC
TTACCCTTTTAGCAAAGAAGATCAGCACTTTAAAAGCTCTGATTTGCACAATGAGCTTAAAAATTTTATAAAAGAACACA
AAATCCCATTTGCCATTGGGGCTCCCTCAAATTTGGACAAAGCCATAGGGATTCAACAAAATTCTATTTATATGGTAGAA
CCAAACCTCAACATTACAAACATATATTCCAAAATATTCTTAGTCCCTTTTGCAGAAAAAATTCCATTTTACGAATATAA
ATTTGTAAGAAACTTTTTTTTAAAAAACTTTAGAATTTTAGGACAGATTGAAGGAAATAAAATCGAAATATTAAAATTGA
AAAAGTTTAAATTTGCTCCTTTAATATGCTATGATGATGCATTTCCAGAGCTTTCAAGGTTTTACAAAACCCAAGGCGCT
AATATATTAGTAAATTTTTCAAACGATTCTTGGTCAAAAACAAATTCAGCAGAATGGCAACACTTTGTTGTGGCTAAATT
TAGAAGCATTGAAAATGGAATCAAAACTATTAGAGCTACAAACTCAGGAATTACTGCAACCATCAACGAATATGGAGAAA
CCATTAAAAAATTGGAAACTTTTAAAAAAGGATACCTATTATCAACCGTAAAACTGTCCCCAACGTTTACAACCATTTAT
GAAAAAATTGGAGACTCGTTTATACATATATTAGTGATGATGTTTTTAATCACAACACTAAGATTTCAATTTATGGAAGA
CAAAAACCAATTATTATCATCCTCTGTAGTAAAAATTAAAGTTTGA

Upstream 100 bases:

>100_bases
AAATAATACAAAAAAATTAATACTATCATATAAAATTATTAATGATAATGTTAAATATATTACACCATTATGTTACTAAT
AATAGTAAAAAAGAGGAAAA

Downstream 100 bases:

>100_bases
CGTTCTTTCCAAAATGGAAAATTTTTAGTAACATCATTTTTTTTGGCATTAACATTAACAGCAAAAGAAGTATCGTTGGA
TTTTGAAATTTTTAAAGACT

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MKTRCFCLAAFSGILTTLAIPNEIKETGYSILGFVAYVPLFIALNKLEDKKALMGLTVFYFIIANSLQNFWLGFFHAFGW
ITFIGVIIGYIPYSLTLGYFLYYSLKSFKNKTMSITMLFTFYDYSRSIGFLAYPWGLAAFTVNNFNNLIQIADIFGVFFV
SFAVYFLNSGIADFLIHKNKTNLLNIAFPTLLITASFTYGMIKKIELKNLLAKEIDSLNIAAIQLNTDPWLPGNDKKGIR
DSIEITEQALKENPKIEFVIWSEGVLTYPFSKEDQHFKSSDLHNELKNFIKEHKIPFAIGAPSNLDKAIGIQQNSIYMVE
PNLNITNIYSKIFLVPFAEKIPFYEYKFVRNFFLKNFRILGQIEGNKIEILKLKKFKFAPLICYDDAFPELSRFYKTQGA
NILVNFSNDSWSKTNSAEWQHFVVAKFRSIENGIKTIRATNSGITATINEYGETIKKLETFKKGYLLSTVKLSPTFTTIY
EKIGDSFIHILVMMFLITTLRFQFMEDKNQLLSSSVVKIKV

Sequences:

>Translated_521_residues
MKTRCFCLAAFSGILTTLAIPNEIKETGYSILGFVAYVPLFIALNKLEDKKALMGLTVFYFIIANSLQNFWLGFFHAFGW
ITFIGVIIGYIPYSLTLGYFLYYSLKSFKNKTMSITMLFTFYDYSRSIGFLAYPWGLAAFTVNNFNNLIQIADIFGVFFV
SFAVYFLNSGIADFLIHKNKTNLLNIAFPTLLITASFTYGMIKKIELKNLLAKEIDSLNIAAIQLNTDPWLPGNDKKGIR
DSIEITEQALKENPKIEFVIWSEGVLTYPFSKEDQHFKSSDLHNELKNFIKEHKIPFAIGAPSNLDKAIGIQQNSIYMVE
PNLNITNIYSKIFLVPFAEKIPFYEYKFVRNFFLKNFRILGQIEGNKIEILKLKKFKFAPLICYDDAFPELSRFYKTQGA
NILVNFSNDSWSKTNSAEWQHFVVAKFRSIENGIKTIRATNSGITATINEYGETIKKLETFKKGYLLSTVKLSPTFTTIY
EKIGDSFIHILVMMFLITTLRFQFMEDKNQLLSSSVVKIKV
>Mature_521_residues
MKTRCFCLAAFSGILTTLAIPNEIKETGYSILGFVAYVPLFIALNKLEDKKALMGLTVFYFIIANSLQNFWLGFFHAFGW
ITFIGVIIGYIPYSLTLGYFLYYSLKSFKNKTMSITMLFTFYDYSRSIGFLAYPWGLAAFTVNNFNNLIQIADIFGVFFV
SFAVYFLNSGIADFLIHKNKTNLLNIAFPTLLITASFTYGMIKKIELKNLLAKEIDSLNIAAIQLNTDPWLPGNDKKGIR
DSIEITEQALKENPKIEFVIWSEGVLTYPFSKEDQHFKSSDLHNELKNFIKEHKIPFAIGAPSNLDKAIGIQQNSIYMVE
PNLNITNIYSKIFLVPFAEKIPFYEYKFVRNFFLKNFRILGQIEGNKIEILKLKKFKFAPLICYDDAFPELSRFYKTQGA
NILVNFSNDSWSKTNSAEWQHFVVAKFRSIENGIKTIRATNSGITATINEYGETIKKLETFKKGYLLSTVKLSPTFTTIY
EKIGDSFIHILVMMFLITTLRFQFMEDKNQLLSSSVVKIKV

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=175, Percent_Identity=28, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_BORBU (O51253)

Other databases:

- EMBL:   AE000783
- PIR:   E70129
- RefSeq:   NP_212371.1
- ProteinModelPortal:   O51253
- EnsemblBacteria:   EBBORT00000009145
- GeneID:   1195074
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0237
- NMPDR:   fig|224326.1.peg.621
- TIGR:   BB_0237
- GeneTree:   EBGT00050000007059
- HOGENOM:   HBG354572
- OMA:   MMAFIRR
- ProtClustDB:   PRK00302
- BioCyc:   BBUR224326:BB_0237-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 59737; Mature: 59737

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbf61a98)-; HASH(0xc676e0c)-; HASH(0xc372b94)-; HASH(0xad8cc5c)-; HASH(0xc2fc4b8)-; HASH(0xc5ff340)-; HASH(0xaf5b95c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRCFCLAAFSGILTTLAIPNEIKETGYSILGFVAYVPLFIALNKLEDKKALMGLTVFY
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FIIANSLQNFWLGFFHAFGWITFIGVIIGYIPYSLTLGYFLYYSLKSFKNKTMSITMLFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
FYDYSRSIGFLAYPWGLAAFTVNNFNNLIQIADIFGVFFVSFAVYFLNSGIADFLIHKNK
EEHHCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCC
TNLLNIAFPTLLITASFTYGMIKKIELKNLLAKEIDSLNIAAIQLNTDPWLPGNDKKGIR
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCH
DSIEITEQALKENPKIEFVIWSEGVLTYPFSKEDQHFKSSDLHNELKNFIKEHKIPFAIG
HHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEC
APSNLDKAIGIQQNSIYMVEPNLNITNIYSKIFLVPFAEKIPFYEYKFVRNFFLKNFRIL
CCCCCHHHCCCCCCCEEEECCCCCHHHHHHHHHEEEHHHHCCCHHHHHHHHHHHHCCEEE
GQIEGNKIEILKLKKFKFAPLICYDDAFPELSRFYKTQGANILVNFSNDSWSKTNSAEWQ
EEECCCEEEEEEEECCCCCCEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHH
HFVVAKFRSIENGIKTIRATNSGITATINEYGETIKKLETFKKGYLLSTVKLSPTFTTIY
HHHHHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHH
EKIGDSFIHILVMMFLITTLRFQFMEDKNQLLSSSVVKIKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEH
>Mature Secondary Structure
MKTRCFCLAAFSGILTTLAIPNEIKETGYSILGFVAYVPLFIALNKLEDKKALMGLTVFY
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FIIANSLQNFWLGFFHAFGWITFIGVIIGYIPYSLTLGYFLYYSLKSFKNKTMSITMLFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
FYDYSRSIGFLAYPWGLAAFTVNNFNNLIQIADIFGVFFVSFAVYFLNSGIADFLIHKNK
EEHHCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCC
TNLLNIAFPTLLITASFTYGMIKKIELKNLLAKEIDSLNIAAIQLNTDPWLPGNDKKGIR
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCH
DSIEITEQALKENPKIEFVIWSEGVLTYPFSKEDQHFKSSDLHNELKNFIKEHKIPFAIG
HHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEC
APSNLDKAIGIQQNSIYMVEPNLNITNIYSKIFLVPFAEKIPFYEYKFVRNFFLKNFRIL
CCCCCHHHCCCCCCCEEEECCCCCHHHHHHHHHEEEHHHHCCCHHHHHHHHHHHHCCEEE
GQIEGNKIEILKLKKFKFAPLICYDDAFPELSRFYKTQGANILVNFSNDSWSKTNSAEWQ
EEECCCEEEEEEEECCCCCCEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHH
HFVVAKFRSIENGIKTIRATNSGITATINEYGETIKKLETFKKGYLLSTVKLSPTFTTIY
HHHHHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHH
EKIGDSFIHILVMMFLITTLRFQFMEDKNQLLSSSVVKIKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9403685