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The map label for this gene is csd

Identifier: 15594430

GI number: 15594430

Start: 79505

End: 80773

Strand: Direct

Name: csd

Synonym: BB0084

Alternate gene names: 15594430

Gene position: 79505-80773 (Clockwise)

Preceding gene: 15594427

Following gene: 15594431

Centisome position: 8.73

GC content: 26.87

Gene sequence:

>1269_bases
ATGGATTTCAAACAAATAAAAAGCAATGTCGAAAAGGTTAAATTTTTAAGAAAAGATTTTCCTATTTTAAATAAAAAATT
TGACAATAAGTATATAATTTACTTTGATAATGCAGCAACCTCTCAAAAGCCCAAAAACGTAATTTATTCTAACGTTGAAT
ATTATGAAAATTACAACGCAAATGTACACAGAAGCGGTCATAAATTTGCAATTCAATCGAGCATAAAAATAGAAAAAACA
AGAGAACTTGTAAAAAATTTCATTAATGCAGAATCTGCAAAAAATATAATATTCACCTCTGGAACTACTGATGGAATTAA
TACCATTGCAAGTTCATTTTTTTATTCAAAATACTTTAAAAAAAAAGATGAAATTATTCTTACAACTCTTGAACATAACA
GCAATTTACTGCCTTGGGTAAATCTTGCAAATTTAGCTAATTTAAAAATTAAATTAGCTAAATTCAATGAAATGGGAATT
ATTACCCCTGAAGAAATTGAAAAACTTATTACAGAAAAAACAAAGCTCATCAGTATTTCAGGAATAAATAATACCCTAGG
AACCATTAATGATTTGGAATCTATTGGAAAAATCGCAAAAAAATACAATATATGTCTCTTTGTAGATGCTGCACAAATGG
CACCTCATATAAAAATAGATGTTAAAAAAATTGGCTGTGATTTTTTGGTATTTTCTGGACATAAAATGCTTGCTCCAACA
GGAATAGGAATTTTATATATTTCAAATAATATGGCTGAAAAACTTCACAGCTCAAAATTGGGGGGAAATACTGTAGAAGA
AATATTTATAGAAAATGAAAAAATTAAATTTAAAGCATCTGATTCTCCTAATAAATTTGAATCGGGAACCCCAAATATTG
CAGGAATTATTGGACTTGAAGAGGCAATAAAATATATTGACAATATTTCTATGGATTTTATTTTAGAGCATGATAAACAG
TTAATCGAATATGGGGTAAAAAAATTACAAGAGCTTGATGAAGTTGAATTTATACTAAATACAAATCTTAAAAGAAATTC
AATAATATCATTTACAGTAAAAAATATCCACTCTCACGATATTGAAACATATCTAGATACAATGGGAATAGCAACCAGAG
CCGGAAGAACTTGTTCCTATGTGGCATTTTTCCCAGAAAATTTAAATAAAGACCATCTTTTAAGAATTAGCTTTTATTTT
TATAATACACAAGAAGAAATTGATAATTTCATATTGGGATTAAAAAAGGTAATAAAAGAGCTTTCATAA

Upstream 100 bases:

>100_bases
ATTATTAATTAATAATTATTTTAAACTTTTTTTGTGAAATAAAAAATAATGATATAATAATTAAAAGCTAAAAATTAAAA
CAAAGGAATTTATAAGAATA

Downstream 100 bases:

>100_bases
AAATTTATAAAATAAAGATCTTAACAAAGTTAATCAAAAATTGTATTTTTGATTAACTTTAATTTCAGGATTAATAAGAA
TTGTTTTAATTTTTAAAAAT

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDFKQIKSNVEKVKFLRKDFPILNKKFDNKYIIYFDNAATSQKPKNVIYSNVEYYENYNANVHRSGHKFAIQSSIKIEKT
RELVKNFINAESAKNIIFTSGTTDGINTIASSFFYSKYFKKKDEIILTTLEHNSNLLPWVNLANLANLKIKLAKFNEMGI
ITPEEIEKLITEKTKLISISGINNTLGTINDLESIGKIAKKYNICLFVDAAQMAPHIKIDVKKIGCDFLVFSGHKMLAPT
GIGILYISNNMAEKLHSSKLGGNTVEEIFIENEKIKFKASDSPNKFESGTPNIAGIIGLEEAIKYIDNISMDFILEHDKQ
LIEYGVKKLQELDEVEFILNTNLKRNSIISFTVKNIHSHDIETYLDTMGIATRAGRTCSYVAFFPENLNKDHLLRISFYF
YNTQEEIDNFILGLKKVIKELS

Sequences:

>Translated_422_residues
MDFKQIKSNVEKVKFLRKDFPILNKKFDNKYIIYFDNAATSQKPKNVIYSNVEYYENYNANVHRSGHKFAIQSSIKIEKT
RELVKNFINAESAKNIIFTSGTTDGINTIASSFFYSKYFKKKDEIILTTLEHNSNLLPWVNLANLANLKIKLAKFNEMGI
ITPEEIEKLITEKTKLISISGINNTLGTINDLESIGKIAKKYNICLFVDAAQMAPHIKIDVKKIGCDFLVFSGHKMLAPT
GIGILYISNNMAEKLHSSKLGGNTVEEIFIENEKIKFKASDSPNKFESGTPNIAGIIGLEEAIKYIDNISMDFILEHDKQ
LIEYGVKKLQELDEVEFILNTNLKRNSIISFTVKNIHSHDIETYLDTMGIATRAGRTCSYVAFFPENLNKDHLLRISFYF
YNTQEEIDNFILGLKKVIKELS
>Mature_422_residues
MDFKQIKSNVEKVKFLRKDFPILNKKFDNKYIIYFDNAATSQKPKNVIYSNVEYYENYNANVHRSGHKFAIQSSIKIEKT
RELVKNFINAESAKNIIFTSGTTDGINTIASSFFYSKYFKKKDEIILTTLEHNSNLLPWVNLANLANLKIKLAKFNEMGI
ITPEEIEKLITEKTKLISISGINNTLGTINDLESIGKIAKKYNICLFVDAAQMAPHIKIDVKKIGCDFLVFSGHKMLAPT
GIGILYISNNMAEKLHSSKLGGNTVEEIFIENEKIKFKASDSPNKFESGTPNIAGIIGLEEAIKYIDNISMDFILEHDKQ
LIEYGVKKLQELDEVEFILNTNLKRNSIISFTVKNIHSHDIETYLDTMGIATRAGRTCSYVAFFPENLNKDHLLRISFYF
YNTQEEIDNFILGLKKVIKELS

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily

Homologues:

Organism=Homo sapiens, GI32307132, Length=231, Percent_Identity=29.8701298701299, Blast_Score=112, Evalue=9e-25,
Organism=Escherichia coli, GI1787970, Length=416, Percent_Identity=34.375, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1789175, Length=410, Percent_Identity=30.2439024390244, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI48994898, Length=408, Percent_Identity=25, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25143064, Length=394, Percent_Identity=24.6192893401015, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=383, Percent_Identity=24.2819843342037, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17533177, Length=289, Percent_Identity=25.2595155709343, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=402, Percent_Identity=25.1243781094527, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20129463, Length=244, Percent_Identity=31.1475409836066, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CSD_BORBU (O51111)

Other databases:

- EMBL:   AE000783
- PIR:   D70110
- RefSeq:   NP_212218.1
- ProteinModelPortal:   O51111
- EnsemblBacteria:   EBBORT00000008616
- GeneID:   1194920
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0084
- NMPDR:   fig|224326.1.peg.468
- TIGR:   BB_0084
- GeneTree:   EBGT00050000007544
- HOGENOM:   HBG635316
- OMA:   YDSTWKE
- ProtClustDB:   CLSK507345
- BioCyc:   BBUR224326:BB_0084-MONOMER
- BRENDA:   2.8.1.7
- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.8.1.7

Molecular weight: Translated: 48125; Mature: 48125

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKQIKSNVEKVKFLRKDFPILNKKFDNKYIIYFDNAATSQKPKNVIYSNVEYYENYNA
CCHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCCCCCCCCCHHHCCCHHHHHCCCC
NVHRSGHKFAIQSSIKIEKTRELVKNFINAESAKNIIFTSGTTDGINTIASSFFYSKYFK
CEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHC
KKDEIILTTLEHNSNLLPWVNLANLANLKIKLAKFNEMGIITPEEIEKLITEKTKLISIS
CCCCEEEEEEECCCCCCCCEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCEEEEEEE
GINNTLGTINDLESIGKIAKKYNICLFVDAAQMAPHIKIDVKKIGCDFLVFSGHKMLAPT
CCCCCCCCHHHHHHHHHHHHHCCEEEEEEHHHHCCCEEEEEEECCCEEEEECCCEEECCC
GIGILYISNNMAEKLHSSKLGGNTVEEIFIENEKIKFKASDSPNKFESGTPNIAGIIGLE
CEEEEEECCHHHHHHHHHCCCCCCHHHHEECCCEEEEEECCCCCCCCCCCCCCEEEEEHH
EAIKYIDNISMDFILEHDKQLIEYGVKKLQELDEVEFILNTNLKRNSIISFTVKNIHSHD
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHH
IETYLDTMGIATRAGRTCSYVAFFPENLNKDHLLRISFYFYNTQEEIDNFILGLKKVIKE
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHH
LS
CC
>Mature Secondary Structure
MDFKQIKSNVEKVKFLRKDFPILNKKFDNKYIIYFDNAATSQKPKNVIYSNVEYYENYNA
CCHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCCCCCCCCCHHHCCCHHHHHCCCC
NVHRSGHKFAIQSSIKIEKTRELVKNFINAESAKNIIFTSGTTDGINTIASSFFYSKYFK
CEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHC
KKDEIILTTLEHNSNLLPWVNLANLANLKIKLAKFNEMGIITPEEIEKLITEKTKLISIS
CCCCEEEEEEECCCCCCCCEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCEEEEEEE
GINNTLGTINDLESIGKIAKKYNICLFVDAAQMAPHIKIDVKKIGCDFLVFSGHKMLAPT
CCCCCCCCHHHHHHHHHHHHHCCEEEEEEHHHHCCCEEEEEEECCCEEEEECCCEEECCC
GIGILYISNNMAEKLHSSKLGGNTVEEIFIENEKIKFKASDSPNKFESGTPNIAGIIGLE
CEEEEEECCHHHHHHHHHCCCCCCHHHHEECCCEEEEEECCCCCCCCCCCCCCEEEEEHH
EAIKYIDNISMDFILEHDKQLIEYGVKKLQELDEVEFILNTNLKRNSIISFTVKNIHSHD
HHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHH
IETYLDTMGIATRAGRTCSYVAFFPENLNKDHLLRISFYFYNTQEEIDNFILGLKKVIKE
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHH
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685