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The map label for this gene is yrvI

Identifier: 50812276

GI number: 50812276

Start: 2820077

End: 2820475

Strand: Reverse

Name: yrvI

Synonym: BSU27590

Alternate gene names: 50812276

Gene position: 2820475-2820077 (Counterclockwise)

Preceding gene: 255767631

Following gene: 16079811

Centisome position: 66.91

GC content: 44.36

Gene sequence:

>399_bases
GTGGACGAAGAGGTCGTCGGCCAAATTGGACAAGGCCTTATGGTGCTGGTCGGCATCACTCACGATGATACAGAAGATGA
TGCAGCTTATTTAGCCGATAAAGTTGTCAATCTCCGTATTTTCGATGACAGTGAAGGGAAAATGAATCTGTCTCTTGTAG
ATATAGGAGGAGAGATTTTATCCGTCTCACAGTTTACGCTTTATGGAGATACGAAAAAAGGGCGCCGGCCGAACTACATG
AACGCGGCCAAACCTGATAAAGCTTTAGGTCTTTATGAAAAATGGAATGACCTGCTTCGTGAAAAAGGAATCAAAGTGGA
GACCGGAACGTTTGGAGCAATGATGGATGTTCAGCTTACAAACTCCGGACCGGTCACGCTCATTATGGATTCAAAATAA

Upstream 100 bases:

>100_bases
TTAAACAGATTAGAGATATCTATTCTGTGCGCCGCGTCATGAACTAAAGGGGTTAGAAAAGAGATTAGTTGTTCAGCGAG
TAACAGAAGCAAGCGTTACA

Downstream 100 bases:

>100_bases
AAAAAGCTGCCAAAAGGCAGCTTTTTTTATTGGAAGTATTTCTCTAATCCGCTTTCGATCCCATCTGTTACTTTTTCTTG
GTATGAATTGCTATGTACAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MDEEVVGQIGQGLMVLVGITHDDTEDDAAYLADKVVNLRIFDDSEGKMNLSLVDIGGEILSVSQFTLYGDTKKGRRPNYM
NAAKPDKALGLYEKWNDLLREKGIKVETGTFGAMMDVQLTNSGPVTLIMDSK

Sequences:

>Translated_132_residues
MDEEVVGQIGQGLMVLVGITHDDTEDDAAYLADKVVNLRIFDDSEGKMNLSLVDIGGEILSVSQFTLYGDTKKGRRPNYM
NAAKPDKALGLYEKWNDLLREKGIKVETGTFGAMMDVQLTNSGPVTLIMDSK
>Mature_132_residues
MDEEVVGQIGQGLMVLVGITHDDTEDDAAYLADKVVNLRIFDDSEGKMNLSLVDIGGEILSVSQFTLYGDTKKGRRPNYM
NAAKPDKALGLYEKWNDLLREKGIKVETGTFGAMMDVQLTNSGPVTLIMDSK

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine. Can also cleave D-aspartyl-tRNA(Asp) and D-tryptophanyl-tRNA(Trp) [C]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=131, Percent_Identity=38.1679389312977, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790320, Length=124, Percent_Identity=47.5806451612903, Blast_Score=125, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI115533292, Length=133, Percent_Identity=45.8646616541353, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6319982, Length=134, Percent_Identity=47.0149253731343, Blast_Score=107, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281361569, Length=131, Percent_Identity=41.2213740458015, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 14488; Mature: 14488

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEEVVGQIGQGLMVLVGITHDDTEDDAAYLADKVVNLRIFDDSEGKMNLSLVDIGGEIL
CCHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHEEEEEEEECCCCEEEEEEEECCCCEE
SVSQFTLYGDTKKGRRPNYMNAAKPDKALGLYEKWNDLLREKGIKVETGTFGAMMDVQLT
EEEEEEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHCCCEEECCCCCEEEEEEEC
NSGPVTLIMDSK
CCCCEEEEEECC
>Mature Secondary Structure
MDEEVVGQIGQGLMVLVGITHDDTEDDAAYLADKVVNLRIFDDSEGKMNLSLVDIGGEIL
CCHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHEEEEEEEECCCCEEEEEEEECCCCEE
SVSQFTLYGDTKKGRRPNYMNAAKPDKALGLYEKWNDLLREKGIKVETGTFGAMMDVQLT
EEEEEEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHCCCEEECCCCCEEEEEEEC
NSGPVTLIMDSK
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 4292198 [H]