Click here to switch to the map view.

The map label for this gene is ykhA

Identifier: 50812222

GI number: 50812222

Start: 1372035

End: 1372553

Strand: Direct

Name: ykhA

Synonym: BSU13030

Alternate gene names: 50812222

Gene position: 1372035-1372553 (Clockwise)

Preceding gene: 255767305

Following gene: 16078369

Centisome position: 32.55

GC content: 46.05

Gene sequence:

>519_bases
ATGGAAACACCGGAAACAAGATTTTGTAAAGAGTCAAAGGTTGTGAAAACCAGCAGGGTGTTCCCGCTTGACACGAACAA
CCATAATACGCTGTTTGGCGGAAAATTAATGAGCTACATAGACGACATTGCCTCTATTTCAGCGGCGCGCCATTGCAGAC
GTGAAACGGTAACAGCTTCAATGGATTCTGTAGATTTTTTAAAGCCGATCGGGCAAAAGGATTCTGTCTGCCTAGAGTCA
TATGTGACATGGGTCGGCACATCTTCCATGGAAGTATTTGTGAAAGTTATTAAGGAGCATTTGATGACTGGCGAACGGGA
ACTCGCTGCCACATCCTTTTTGACATTTGTCGCATTAGATTCAAATGGCAAGCCGGTGCCTGTACCGAGGGTTGTACCGG
AAACAGAAGAAGAAATCATGCTGCATAATACAGCTGTACAGCGTGCTAATGAACGTAAGAACCGCAAGAGACACAGCCAG
GCGCTTGCAAATGCGCTCGGAACTGATAAGCCTTGGTGA

Upstream 100 bases:

>100_bases
TAAACCATTTTAAATTTTAGACAAATGGAAGAGAATATTGTTTAATAGGAGAATATAAGTGCATTTAGCTAAAAGATCAG
ACATCAAAGGGGAGAAAGGT

Downstream 100 bases:

>100_bases
ACGTTAAACCCAAAACATAAGTTGTTTTGGGTTTTTTTGTACTTTTCAATGGTGATTATTACAATGGTTAGTCCGTTTTT
GCTAGGGGATTCTATAAAAA

Product: acyl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
METPETRFCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHCRRETVTASMDSVDFLKPIGQKDSVCLES
YVTWVGTSSMEVFVKVIKEHLMTGERELAATSFLTFVALDSNGKPVPVPRVVPETEEEIMLHNTAVQRANERKNRKRHSQ
ALANALGTDKPW

Sequences:

>Translated_172_residues
METPETRFCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHCRRETVTASMDSVDFLKPIGQKDSVCLES
YVTWVGTSSMEVFVKVIKEHLMTGERELAATSFLTFVALDSNGKPVPVPRVVPETEEEIMLHNTAVQRANERKNRKRHSQ
ALANALGTDKPW
>Mature_172_residues
METPETRFCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHCRRETVTASMDSVDFLKPIGQKDSVCLES
YVTWVGTSSMEVFVKVIKEHLMTGERELAATSFLTFVALDSNGKPVPVPRVVPETEEEIMLHNTAVQRANERKNRKRHSQ
ALANALGTDKPW

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family

Homologues:

Organism=Homo sapiens, GI32528284, Length=121, Percent_Identity=37.1900826446281, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI32528282, Length=121, Percent_Identity=37.1900826446281, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI32528286, Length=121, Percent_Identity=37.1900826446281, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI75709208, Length=121, Percent_Identity=37.1900826446281, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI22165355, Length=141, Percent_Identity=34.7517730496454, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI22165400, Length=141, Percent_Identity=34.7517730496454, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI18640736, Length=155, Percent_Identity=28.3870967741935, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787506, Length=123, Percent_Identity=31.7073170731707, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKHA_BACSU (P49851)

Other databases:

- EMBL:   D78189
- EMBL:   AJ002571
- EMBL:   AL009126
- PIR:   E69856
- RefSeq:   NP_389186.2
- ProteinModelPortal:   P49851
- SMR:   P49851
- EnsemblBacteria:   EBBACT00000000417
- GeneID:   937988
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13030
- NMPDR:   fig|224308.1.peg.1305
- GenoList:   BSU13030
- GeneTree:   EBGT00050000001640
- HOGENOM:   HBG499693
- OMA:   FPNTTNH
- ProtClustDB:   CLSK928127
- BioCyc:   BSUB:BSU13030-MONOMER
- InterPro:   IPR006683

Pfam domain/function: PF03061 4HBT

EC number: 3.1.2.- [C]

Molecular weight: Translated: 19298; Mature: 19298

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METPETRFCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHCRRETVTAS
CCCCCCHHHHHHCHHHHCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MDSVDFLKPIGQKDSVCLESYVTWVGTSSMEVFVKVIKEHLMTGERELAATSFLTFVALD
CCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEC
SNGKPVPVPRVVPETEEEIMLHNTAVQRANERKNRKRHSQALANALGTDKPW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
METPETRFCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHCRRETVTAS
CCCCCCHHHHHHCHHHHCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MDSVDFLKPIGQKDSVCLESYVTWVGTSSMEVFVKVIKEHLMTGERELAATSFLTFVALD
CCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHEEEEEC
SNGKPVPVPRVVPETEEEIMLHNTAVQRANERKNRKRHSQALANALGTDKPW
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751