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The map label for this gene is yisV

Identifier: 50812213

GI number: 50812213

Start: 1166737

End: 1168191

Strand: Direct

Name: yisV

Synonym: BSU10880

Alternate gene names: 50812213

Gene position: 1166737-1168191 (Clockwise)

Preceding gene: 16078148

Following gene: 16078154

Centisome position: 27.68

GC content: 49.97

Gene sequence:

>1455_bases
ATGACCTTGTCGCAATGGCAGCCAAGCCGAAAGTCGGATGTTCCGCTGCATCGGCAGATCGAACAATATATGAAAGACAA
GATTCTTCACGGAGAGTGGGCTGTAGGGACGAAAATCCCCTCACAGAGAACGCTGGCCGACATGTTTCAAGTCAACCGCA
GCACAGTCACAGCAGCCATAGATGAACTCACGTCTCAAGGCTTGTTAGAGGGAAGAAAAGGCGGCGGTACGAAGGTTGTA
AACAGTACTTGGAGCGTGCTGACGGCTGAGCCTCCGCTTGATTGGAGCGATTACGTCCGTTCGGGCATTCATCGCGCCAA
TTCTTCCATCATTCAAGCTATTAATCAGAACGAACCAAGAGCGGATATCATCAGATTAGGAACTGGAGAACTTTCACCGG
ATCTTGTGCCTGCTGACACAATTGGACGGATGTTTCAGCAAATCAATCCGGGCGTCCTGTCTTTAGGATATGAGCAGCCG
AAAGGAAACCGTCAGCTGCGGGAGGCAGTGGCCGACCATTTAAAAGGAAAGAAGATCCATGTGTCACCGTCTGCAATTTT
AATTGTGTCCGGTGCACTTCAGGCACTTCAGCTCATCTCAATTGGACTTTTAAAACGAGATTCTGTCATTTTGACGGAGA
AGCCGTCCTACCTTCAATCCTTGCATGTATTTCAATCAGCTGGGATGCGGCTTCGCGGCTTGCCGATGGATGATGAAGGG
GTCAAAGCGGGGCTTGTTTCTTCTAATCGAAAACAATATGGAGGACAGCTGCTTTACACGATTCCGTCGTTTCATAATCC
GACAGGCACAGTCATGTCAGAGCAGCGAAGGAAAGAGATCATCAGCCTGTCAAAAAAAGAGCAGATGCCCATCATTGAGG
ATGATGCGTACGGTGATTTATGGTTTGAAGAAAAACCGCCGCAGCCGTTGAAAGCAATGGATCATGAGGGCAATATTCTG
TATCTGGGCGCGTTTTCAAAAACGGTTAGCCCCGGTCTGCGAATCGGCTGGCTTGCCGGTCCGGAGCCGGTTATTGAAAG
GCTGGCGGACATTAAAATGCAGACAGACTACGGATCAAGCGGCCTGTCCCAGTGGGCGGCTGCCGAGTGGCTGTCACAGG
GATATTATGAAGAGCATCTGACTTGGGTACGCAGGAAGCTTAAAGAAAGGAGAGACGCCGCCGTTCATTTTCTCGAGCGG
TATGCCGGGGACATTGCCACGTGGCGGATTCCCGCAGGCGGCTTTTATATTTGGGTGACATTTCACAAAAACCTGCCTGT
CAGCCGTTTCTTTTATGAATTGCTGAAACGGCAGGTGCTTGTGAATCCCGGCTATATTTATGACGGTGAAGACCGAAACA
GCATCAGGCTGTCATATTCCTATGCATCTCTTGGAGATTTGGAAACTGGCATTAAAGCGGCAGCTGAAACAGCACGCCGC
CTGATGATGTCCTAG

Upstream 100 bases:

>100_bases
CACATTTTTTTTCAATCATAAGAGAGATTGTCACTAAAGTCTCCAGCCATTTGGTTGGGTTAGGAACCAGCCAAATGTAT
AATGTGTAAAAAAGGGGGGC

Downstream 100 bases:

>100_bases
GCTTTGGTTATACGATGACAGCTCCCAGTGCCCTGGCGAAGGCAATCGCGTGCTCAGGTGCGATTTTGCAGCCTTTCAAT
TTGTCGAGGGAGACATGAAG

Product: PLP-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTLSQWQPSRKSDVPLHRQIEQYMKDKILHGEWAVGTKIPSQRTLADMFQVNRSTVTAAIDELTSQGLLEGRKGGGTKVV
NSTWSVLTAEPPLDWSDYVRSGIHRANSSIIQAINQNEPRADIIRLGTGELSPDLVPADTIGRMFQQINPGVLSLGYEQP
KGNRQLREAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLHVFQSAGMRLRGLPMDDEG
VKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEIISLSKKEQMPIIEDDAYGDLWFEEKPPQPLKAMDHEGNIL
YLGAFSKTVSPGLRIGWLAGPEPVIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLER
YAGDIATWRIPAGGFYIWVTFHKNLPVSRFFYELLKRQVLVNPGYIYDGEDRNSIRLSYSYASLGDLETGIKAAAETARR
LMMS

Sequences:

>Translated_484_residues
MTLSQWQPSRKSDVPLHRQIEQYMKDKILHGEWAVGTKIPSQRTLADMFQVNRSTVTAAIDELTSQGLLEGRKGGGTKVV
NSTWSVLTAEPPLDWSDYVRSGIHRANSSIIQAINQNEPRADIIRLGTGELSPDLVPADTIGRMFQQINPGVLSLGYEQP
KGNRQLREAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLHVFQSAGMRLRGLPMDDEG
VKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEIISLSKKEQMPIIEDDAYGDLWFEEKPPQPLKAMDHEGNIL
YLGAFSKTVSPGLRIGWLAGPEPVIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLER
YAGDIATWRIPAGGFYIWVTFHKNLPVSRFFYELLKRQVLVNPGYIYDGEDRNSIRLSYSYASLGDLETGIKAAAETARR
LMMS
>Mature_483_residues
TLSQWQPSRKSDVPLHRQIEQYMKDKILHGEWAVGTKIPSQRTLADMFQVNRSTVTAAIDELTSQGLLEGRKGGGTKVVN
STWSVLTAEPPLDWSDYVRSGIHRANSSIIQAINQNEPRADIIRLGTGELSPDLVPADTIGRMFQQINPGVLSLGYEQPK
GNRQLREAVADHLKGKKIHVSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLHVFQSAGMRLRGLPMDDEGV
KAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEIISLSKKEQMPIIEDDAYGDLWFEEKPPQPLKAMDHEGNILY
LGAFSKTVSPGLRIGWLAGPEPVIERLADIKMQTDYGSSGLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLERY
AGDIATWRIPAGGFYIWVTFHKNLPVSRFFYELLKRQVLVNPGYIYDGEDRNSIRLSYSYASLGDLETGIKAAAETARRL
MMS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain

Homologues:

Organism=Homo sapiens, GI7705897, Length=326, Percent_Identity=26.9938650306748, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI33469970, Length=326, Percent_Identity=26.9938650306748, Blast_Score=122, Evalue=7e-28,
Organism=Escherichia coli, GI1790797, Length=491, Percent_Identity=25.050916496945, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI1787710, Length=439, Percent_Identity=24.1457858769932, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1788722, Length=303, Percent_Identity=24.4224422442244, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321236, Length=346, Percent_Identity=23.9884393063584, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321000, Length=243, Percent_Identity=26.7489711934156, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321929, Length=273, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356535, Length=401, Percent_Identity=23.6907730673317, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YISV_BACSU (Q796Q6)

Other databases:

- EMBL:   AL009126
- RefSeq:   NP_388968.2
- ProteinModelPortal:   Q796Q6
- EnsemblBacteria:   EBBACT00000002756
- GeneID:   936360
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU10880
- GenoList:   BSU10880
- GeneTree:   EBGT00070000031923
- HOGENOM:   HBG752297
- OMA:   NDHIRIS
- PhylomeDB:   Q796Q6
- ProtClustDB:   CLSK2762998
- BioCyc:   BSUB:BSU10880-MONOMER
- GO:   GO:0005622
- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00035
- SMART:   SM00345

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR; SSF53383 PyrdxlP-dep_Trfase_major

EC number: NA

Molecular weight: Translated: 54275; Mature: 54144

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSQWQPSRKSDVPLHRQIEQYMKDKILHGEWAVGTKIPSQRTLADMFQVNRSTVTAAI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCHHHHHHHH
DELTSQGLLEGRKGGGTKVVNSTWSVLTAEPPLDWSDYVRSGIHRANSSIIQAINQNEPR
HHHHHHHHHCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
ADIIRLGTGELSPDLVPADTIGRMFQQINPGVLSLGYEQPKGNRQLREAVADHLKGKKIH
CCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCEEE
VSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLHVFQSAGMRLRGLPMDDEG
ECCCEEEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCEEECCCCCCCC
VKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEIISLSKKEQMPIIEDDAYGDL
CEECCCCCCHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
WFEEKPPQPLKAMDHEGNILYLGAFSKTVSPGLRIGWLAGPEPVIERLADIKMQTDYGSS
CCCCCCCCHHHHCCCCCCEEEEECCCHHCCCCCEEEECCCCHHHHHHHHHCEEECCCCCC
GLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLERYAGDIATWRIPAGGFYIWVT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEE
FHKNLPVSRFFYELLKRQVLVNPGYIYDGEDRNSIRLSYSYASLGDLETGIKAAAETARR
EECCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
LMMS
HHCC
>Mature Secondary Structure 
TLSQWQPSRKSDVPLHRQIEQYMKDKILHGEWAVGTKIPSQRTLADMFQVNRSTVTAAI
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCHHHHHHHH
DELTSQGLLEGRKGGGTKVVNSTWSVLTAEPPLDWSDYVRSGIHRANSSIIQAINQNEPR
HHHHHHHHHCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
ADIIRLGTGELSPDLVPADTIGRMFQQINPGVLSLGYEQPKGNRQLREAVADHLKGKKIH
CCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCEEE
VSPSAILIVSGALQALQLISIGLLKRDSVILTEKPSYLQSLHVFQSAGMRLRGLPMDDEG
ECCCEEEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCEEECCCCCCCC
VKAGLVSSNRKQYGGQLLYTIPSFHNPTGTVMSEQRRKEIISLSKKEQMPIIEDDAYGDL
CEECCCCCCHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
WFEEKPPQPLKAMDHEGNILYLGAFSKTVSPGLRIGWLAGPEPVIERLADIKMQTDYGSS
CCCCCCCCHHHHCCCCCCEEEEECCCHHCCCCCEEEECCCCHHHHHHHHHCEEECCCCCC
GLSQWAAAEWLSQGYYEEHLTWVRRKLKERRDAAVHFLERYAGDIATWRIPAGGFYIWVT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEE
FHKNLPVSRFFYELLKRQVLVNPGYIYDGEDRNSIRLSYSYASLGDLETGIKAAAETARR
EECCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHH
LMMS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377