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The map label for this gene is yyaJ

Identifier: 255767876

GI number: 255767876

Start: 4194389

End: 4195744

Strand: Direct

Name: yyaJ

Synonym: BSU40840

Alternate gene names: 255767876

Gene position: 4194389-4195744 (Clockwise)

Preceding gene: 16081134

Following gene: 16081147

Centisome position: 99.5

GC content: 45.35

Gene sequence:

>1356_bases
ATGAATACGATCTTCAAACAAAAGAATACACATCCTTTCTCAAACGCAGCGAATCGTTTAGACCGCCTTCCGATTTCACG
CGTTCATTTCCAAGTGTTAACCGCTCTCGGCATTGTTTATTTCTTTGATCTCGCAGATTTATTTACCCTCAGCAACGTAG
CGCCGGCACTGATCGAGCATTGGGGCATCCCGCTTTCAACTATTGCTAACGTAACGGCCGCTTCGTTTTTAGGCATGTTT
TTAGGCGCTTCACTGGGCGGACGGCTGTCCGATCGAATCGGCCGCAAAAAAGCCTTAAATCTATTTGTCTTTGTTTTCTC
AATCGCATCGCTATGCAATGCTGCGGCATGGGACATTCCATCTTTAATGACATTCCGTTTCCTCACCGGATTTGGCGTTG
CAGCCGCCATGGTCATTACGAATAGCTATTTGGCGGAATTTTTCCCTTCAAGTGTACGTGGAAAATATATTTCTTTTTGT
GCCATGATTGGATTGATTGGGGTTCCGATCACCAACATTGTGTCTGCCTTTGTCATTCCTCTTGGTTCATGGGGATGGAG
GCTAGTATTTGTATGGGGTGCCGTCGGCCTTATTTATTTTTTCTTCATCCACCGTCTGGAAGAGTCACCTCGCTGGCACG
AAAATCGCGGGGAATATGCGAAAGCCGATGCGATCCTCACCCGAATTGAAGAACAGGTTGAAAAGGAGAAAGGCCCGCTT
CCGGCAGCATCCCAGCCTAAAGTAAGCGAAACTGTTAAGCAGAATGCAGGTTACGCAGGCTTATTGAAAGGCAGAAACCT
CAAAATTACCATCGTATTATCTGCTGTATGGATTTTTGAAACGTTTGGGTTTTACGGATTTGCTTCATGGGTTCCAAGCC
TGCTAAAAAGCAATGGCGTAACCATGGAAAATACATTATGGTATAACGTATTGCATTCCGTCGGCGCTCCACTTGGCGCA
CTGCTCGGCTCCATGATTTCCGAAAGATTTCAAAGAAAATGGATTTTAGCTGCGAGTGCGTTTCTGACGGCCATCGCCGG
GCTCTTATATGGTATGACTTTTATTCCCATCATGATCATTGTATTTGGTTTTATCGTGAATATCACAGAACGGGTCTTTA
CCTCGAACTTATACGCCTATACATCTGAACCTTATCCGACTGAATACCGCTCGTCTGGCAGCGGTTTAGCCTATGGTCTT
GGCCGTTTTTCAAACATTTTTGGCTCATTGCTTGTCGGATTTATTGCCGTTCAGCTCGGCTATATCAGCGTCTTCTTATT
TATTGGGGGCTGTTGGCTCGCATGCTCCTTGCTGTTAATCTTCTTCGGTCCTAATACGAATGCAAAACAGATTTAA

Upstream 100 bases:

>100_bases
ATCTAGTGATTTGAACTCTGTTGCCAATGAACCAAGATACTTATAATAGTCCCAAGAGGGGAATTTTCAGTCTTTTCTAC
TACTCAAAAGGGGGTTTTTT

Downstream 100 bases:

>100_bases
AAAAGTCAGTGCGGATCTGCCGCACTGATCTCATTACAATTGCTTCAAAATCCTTGCGGGGTTTCCGCCTACAACAGTAT
TAGCGGGTACATCCTTAGTG

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MNTIFKQKNTHPFSNAANRLDRLPISRVHFQVLTALGIVYFFDLADLFTLSNVAPALIEHWGIPLSTIANVTAASFLGMF
LGASLGGRLSDRIGRKKALNLFVFVFSIASLCNAAAWDIPSLMTFRFLTGFGVAAAMVITNSYLAEFFPSSVRGKYISFC
AMIGLIGVPITNIVSAFVIPLGSWGWRLVFVWGAVGLIYFFFIHRLEESPRWHENRGEYAKADAILTRIEEQVEKEKGPL
PAASQPKVSETVKQNAGYAGLLKGRNLKITIVLSAVWIFETFGFYGFASWVPSLLKSNGVTMENTLWYNVLHSVGAPLGA
LLGSMISERFQRKWILAASAFLTAIAGLLYGMTFIPIMIIVFGFIVNITERVFTSNLYAYTSEPYPTEYRSSGSGLAYGL
GRFSNIFGSLLVGFIAVQLGYISVFLFIGGCWLACSLLLIFFGPNTNAKQI

Sequences:

>Translated_451_residues
MNTIFKQKNTHPFSNAANRLDRLPISRVHFQVLTALGIVYFFDLADLFTLSNVAPALIEHWGIPLSTIANVTAASFLGMF
LGASLGGRLSDRIGRKKALNLFVFVFSIASLCNAAAWDIPSLMTFRFLTGFGVAAAMVITNSYLAEFFPSSVRGKYISFC
AMIGLIGVPITNIVSAFVIPLGSWGWRLVFVWGAVGLIYFFFIHRLEESPRWHENRGEYAKADAILTRIEEQVEKEKGPL
PAASQPKVSETVKQNAGYAGLLKGRNLKITIVLSAVWIFETFGFYGFASWVPSLLKSNGVTMENTLWYNVLHSVGAPLGA
LLGSMISERFQRKWILAASAFLTAIAGLLYGMTFIPIMIIVFGFIVNITERVFTSNLYAYTSEPYPTEYRSSGSGLAYGL
GRFSNIFGSLLVGFIAVQLGYISVFLFIGGCWLACSLLLIFFGPNTNAKQI
>Mature_451_residues
MNTIFKQKNTHPFSNAANRLDRLPISRVHFQVLTALGIVYFFDLADLFTLSNVAPALIEHWGIPLSTIANVTAASFLGMF
LGASLGGRLSDRIGRKKALNLFVFVFSIASLCNAAAWDIPSLMTFRFLTGFGVAAAMVITNSYLAEFFPSSVRGKYISFC
AMIGLIGVPITNIVSAFVIPLGSWGWRLVFVWGAVGLIYFFFIHRLEESPRWHENRGEYAKADAILTRIEEQVEKEKGPL
PAASQPKVSETVKQNAGYAGLLKGRNLKITIVLSAVWIFETFGFYGFASWVPSLLKSNGVTMENTLWYNVLHSVGAPLGA
LLGSMISERFQRKWILAASAFLTAIAGLLYGMTFIPIMIIVFGFIVNITERVFTSNLYAYTSEPYPTEYRSSGSGLAYGL
GRFSNIFGSLLVGFIAVQLGYISVFLFIGGCWLACSLLLIFFGPNTNAKQI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family

Homologues:

Organism=Homo sapiens, GI24308167, Length=442, Percent_Identity=26.6968325791855, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI166064021, Length=355, Percent_Identity=25.0704225352113, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI24497476, Length=373, Percent_Identity=26.2734584450402, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI20070188, Length=373, Percent_Identity=26.2734584450402, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI7662270, Length=320, Percent_Identity=21.25, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI216548223, Length=262, Percent_Identity=22.9007633587786, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4507005, Length=373, Percent_Identity=23.3243967828418, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI213021148, Length=451, Percent_Identity=23.059866962306, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1788068, Length=449, Percent_Identity=28.5077951002227, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1788074, Length=439, Percent_Identity=30.2961275626424, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1790463, Length=317, Percent_Identity=23.6593059936909, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082159, Length=425, Percent_Identity=24.7058823529412, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786229, Length=446, Percent_Identity=22.4215246636771, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081723, Length=361, Percent_Identity=27.7008310249307, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789312, Length=309, Percent_Identity=24.9190938511327, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082231, Length=428, Percent_Identity=21.0280373831776, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789207, Length=230, Percent_Identity=26.9565217391304, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32564663, Length=433, Percent_Identity=26.7898383371824, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565976, Length=291, Percent_Identity=27.4914089347079, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71988651, Length=322, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17565978, Length=299, Percent_Identity=25.752508361204, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71986689, Length=389, Percent_Identity=23.9074550128535, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193202825, Length=389, Percent_Identity=23.9074550128535, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320595, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922874, Length=400, Percent_Identity=26, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24640198, Length=495, Percent_Identity=22.020202020202, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640196, Length=495, Percent_Identity=22.020202020202, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640200, Length=495, Percent_Identity=22.020202020202, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24652793, Length=348, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24652795, Length=267, Percent_Identity=26.5917602996255, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922616, Length=361, Percent_Identity=25.4847645429363, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YYAJ_BACSU (P37514)

Other databases:

- EMBL:   D26185
- EMBL:   L16865
- EMBL:   AL009126
- PIR:   S66008
- RefSeq:   NP_391964.2
- ProteinModelPortal:   P37514
- EnsemblBacteria:   EBBACT00000002987
- GeneID:   937884
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU40840
- NMPDR:   fig|224308.1.peg.4090
- GenoList:   BSU40840
- GeneTree:   EBGT00070000031889
- HOGENOM:   HBG715489
- PhylomeDB:   P37514
- ProtClustDB:   CLSK888210
- BioCyc:   BSUB:BSU40840-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828

Pfam domain/function: PF00083 Sugar_tr; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 49672; Mature: 49672

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50850 MFS; PS00216 SUGAR_TRANSPORT_1; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13a96d90)-; HASH(0x139e732c)-; HASH(0x1378e808)-; HASH(0x13391d3c)-; HASH(0x13168b38)-; HASH(0x12d5d3fc)-; HASH(0x1345f1d4)-; HASH(0x13084268)-; HASH(0x13a706e0)-; HASH(0x137cb834)-; HASH(0x1356af9c)-; HASH(0x13453494)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure
MNTIFKQKNTHPFSNAANRLDRLPISRVHFQVLTALGIVYFFDLADLFTLSNVAPALIEH
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIPLSTIANVTAASFLGMFLGASLGGRLSDRIGRKKALNLFVFVFSIASLCNAAAWDIP
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SLMTFRFLTGFGVAAAMVITNSYLAEFFPSSVRGKYISFCAMIGLIGVPITNIVSAFVIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LGSWGWRLVFVWGAVGLIYFFFIHRLEESPRWHENRGEYAKADAILTRIEEQVEKEKGPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
PAASQPKVSETVKQNAGYAGLLKGRNLKITIVLSAVWIFETFGFYGFASWVPSLLKSNGV
CCCCCCHHHHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TMENTLWYNVLHSVGAPLGALLGSMISERFQRKWILAASAFLTAIAGLLYGMTFIPIMII
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFGFIVNITERVFTSNLYAYTSEPYPTEYRSSGSGLAYGLGRFSNIFGSLLVGFIAVQLG
HHHHHHHHHHHHHHHCHHEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YISVFLFIGGCWLACSLLLIFFGPNTNAKQI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377