Click here to switch to the map view.

The map label for this gene is copA

Identifier: 255767765

GI number: 255767765

Start: 3441121

End: 3443529

Strand: Reverse

Name: copA

Synonym: BSU33500

Alternate gene names: 255767765

Gene position: 3443529-3441121 (Counterclockwise)

Preceding gene: 16080404

Following gene: 255767764

Centisome position: 81.69

GC content: 47.7

Gene sequence:

>2409_bases
TTGAGTGAACAAAAGGAAATCGCGATGCAGGTCTCTGGTATGACCTGTGCGGCATGTGCTGCCAGAATTGAAAAAGGCCT
GAAGCGGATGCCCGGTGTCACGGATGCAAATGTTAATCTGGCAACGGAAACATCAAATGTAATCTACGATCCTGCTGAAA
CAGGGACTGCAGCGATTCAGGAAAAAATAGAGAAGCTGGGCTATCACGTCGTTACAGAAAAAGCTGAATTCGATATTGAG
GGCATGACCTGTGCGGCTTGCGCCAATCGGATTGAAAAACGGCTTAACAAAATAGAAGGCGTCGCAAATGCACCAGTAAA
CTTCGCTTTAGAAACAGTTACGGTCGAATACAATCCAAAAGAAGCGTCTGTCAGCGATTTGAAAGAAGCGGTAGATAAGC
TTGGATATAAGCTAAAGTTGAAGGGTGAACAGGACAGTGAGGCTGCTGCTAAAAAGAAAGAAGAACGGAAGCAAACGGCG
AGACTGATTTTTTCAGCTGTCCTGTCATTTCCATTGCTTTGGGCGATGGTGAGCCATTTTACATTTACATCATTCATTTG
GGTACCGGATATATTTCTCAATCCGTGGATGCAGTTTGCGCTGGCGACACCAGTCCAGTTTCTGATCGGCTGGCCGTTTT
ATGTGGGTGCGTATAAGGCGCTTAGAAATAAAAGCGCCAATATGGATGTATTGGTCGCCCTCGGTACGACGGCTGCTTAC
GCTTATAGTCTTTATCTAACTTTTCAAAGCATTGGCTCTCACGGGCATACAGACGGCCTTTATTATGAAACAAGCGCGAT
TTTGCTGACGCTGATTTTATTAGGCAAGTTGTTTGAAACAAAAGCAAAAGGCCGTTCCTCGGATGCGATTAAAAAGCTGA
TGAAGCTTCAAGCGAAAACAGCTACTGTTGTAAGAGACGGACAGGAGCAAATCATCCCGATCGACGAAGTGCTTGTTAAT
GACATTGTTTACGTCAAACCTGGCGAACGAATTCCTGTCGACGGAGAAGTGGTTGAAGGCCGTTCAGCGGTTGACGAATC
GATGATTACAGGAGAAAGTCTTCCTGTTGACAAAAATCCTGGTGACAGCGTGACAGGTTCAACCGTTAACGCAAACGGCT
TTCTGAAAATTAAAGCTGTCAACGTCGGAAAGGATACTGCGCTTTCTCATATCATCAAAATTGTTGAGGAAGCACAAGGG
TCAAAAGCGCCGATCCAGCGTCTCGCTGACCAGATTTCAGGCATTTTTGTACCCATTGTATTGGGGATTGCGGTTCTCAC
TTTTCTCATTTGGTATCTTTGGGCGGCTCCTGGCGATTTTGCCGAAGCGATCAGCAAGTTCATTGCGGTTCTTGTCATTG
CCTGTCCTTGCGCCCTCGGTCTTGCCACTCCGACGAGCATAATGGCTGGATCTGGACGCGCTGCTGAATTCGGGATTTTA
TTTAAAGGCGGCGAGCATTTAGAAAAAACACATCGTCTCGATACAATTGTTCTTGATAAAACCGGAACCGTGACAAACGG
GAAGCCGCGTCTGACGGATGCCATTCCATTCGGCCGTTTTGAAGAAAAAGATTTGCTTCAATTTGCAGCGGCAGCGGAAA
CGGGATCAGAGCATCCGCTTGGCGAAGCGATTATTGCTGGCGTGAAAGATAAAGGGCTTGAGATACCGAAACTTACCCGC
TTTGAAGCAAAAGTCGGCGCAGGCATTTTGGCTGAAGCCGGAGGAAAAAGCATTCTCGTCGGCACAAGAAAATTAATGGA
GAGCGAACAGGTTGAGCATGGGGCTCTTCTCGCCCAAATGGAAGAGCTAGAGGCCGAAGGGAAAACAGTTATGCTTGTAT
CCATTGATGGAGAAGCAGCGGGGCTAGTAGCAGTTGCAGATACGATTAAGGATACGTCGCGGAAGGCTGTTGCCCGTCTG
AAAGAGTTGGGTCTTGATGTCATCATGATGACAGGAGACAATCGCAGAACCGCAGAAGCCATCGCGAAGGAAGCGGGAAT
TGCGAATATCATTGCGGAAGTTCTTCCTGAACAAAAGGCGGCGGAAATCGCCCGCTTGCAAAAAGAAGGCCGCCAGACAG
CAATGGTAGGCGACGGAATTAACGATGCGCCGGCGCTTGCCACAGCTGACATCGGCATGGCGATTGGAACTGGCACGGAC
ATTGCCATGGAAACAGCAGACATTACACTTATTCGCGGCGATCTGAACAGCATTGCCGACGCAATCCGCATGAGCAGATT
GACAATGAAAAACATTAAACAAAACTTATTCTGGGCGCTTGGCTATAACAGCCTCGGCATCCCAATCGCAGCACTTGGAT
TTTTAGCACCGTGGATAGCAGGAGCAGCAATGGCATTCAGCTCCGTTTCCGTTGTTCTGAATGCTCTTCGTCTGCAAAAA
GTAAAATGA

Upstream 100 bases:

>100_bases
ATGACGTAGCCAAGTGATTCAAGGTATCGCGCCTTTAGGGAGGCGCGATATTTCTTTCATTTTTATATACCCCCCAGGTG
TATATAAAGGAGTGAGTATG

Downstream 100 bases:

>100_bases
AAAACCGGCTATATGCCGGTTTTTGTTTTTCATTGACACTTTCTTGGAAAACAACATATAATAGGTGTAACTTATATATG
AGTATATGCTCATATATATA

Product: copper transporter ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: Protein CopA

Number of amino acids: Translated: 802; Mature: 801

Protein sequence:

>802_residues
MSEQKEIAMQVSGMTCAACAARIEKGLKRMPGVTDANVNLATETSNVIYDPAETGTAAIQEKIEKLGYHVVTEKAEFDIE
GMTCAACANRIEKRLNKIEGVANAPVNFALETVTVEYNPKEASVSDLKEAVDKLGYKLKLKGEQDSEAAAKKKEERKQTA
RLIFSAVLSFPLLWAMVSHFTFTSFIWVPDIFLNPWMQFALATPVQFLIGWPFYVGAYKALRNKSANMDVLVALGTTAAY
AYSLYLTFQSIGSHGHTDGLYYETSAILLTLILLGKLFETKAKGRSSDAIKKLMKLQAKTATVVRDGQEQIIPIDEVLVN
DIVYVKPGERIPVDGEVVEGRSAVDESMITGESLPVDKNPGDSVTGSTVNANGFLKIKAVNVGKDTALSHIIKIVEEAQG
SKAPIQRLADQISGIFVPIVLGIAVLTFLIWYLWAAPGDFAEAISKFIAVLVIACPCALGLATPTSIMAGSGRAAEFGIL
FKGGEHLEKTHRLDTIVLDKTGTVTNGKPRLTDAIPFGRFEEKDLLQFAAAAETGSEHPLGEAIIAGVKDKGLEIPKLTR
FEAKVGAGILAEAGGKSILVGTRKLMESEQVEHGALLAQMEELEAEGKTVMLVSIDGEAAGLVAVADTIKDTSRKAVARL
KELGLDVIMMTGDNRRTAEAIAKEAGIANIIAEVLPEQKAAEIARLQKEGRQTAMVGDGINDAPALATADIGMAIGTGTD
IAMETADITLIRGDLNSIADAIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIAGAAMAFSSVSVVLNALRLQK
VK

Sequences:

>Translated_802_residues
MSEQKEIAMQVSGMTCAACAARIEKGLKRMPGVTDANVNLATETSNVIYDPAETGTAAIQEKIEKLGYHVVTEKAEFDIE
GMTCAACANRIEKRLNKIEGVANAPVNFALETVTVEYNPKEASVSDLKEAVDKLGYKLKLKGEQDSEAAAKKKEERKQTA
RLIFSAVLSFPLLWAMVSHFTFTSFIWVPDIFLNPWMQFALATPVQFLIGWPFYVGAYKALRNKSANMDVLVALGTTAAY
AYSLYLTFQSIGSHGHTDGLYYETSAILLTLILLGKLFETKAKGRSSDAIKKLMKLQAKTATVVRDGQEQIIPIDEVLVN
DIVYVKPGERIPVDGEVVEGRSAVDESMITGESLPVDKNPGDSVTGSTVNANGFLKIKAVNVGKDTALSHIIKIVEEAQG
SKAPIQRLADQISGIFVPIVLGIAVLTFLIWYLWAAPGDFAEAISKFIAVLVIACPCALGLATPTSIMAGSGRAAEFGIL
FKGGEHLEKTHRLDTIVLDKTGTVTNGKPRLTDAIPFGRFEEKDLLQFAAAAETGSEHPLGEAIIAGVKDKGLEIPKLTR
FEAKVGAGILAEAGGKSILVGTRKLMESEQVEHGALLAQMEELEAEGKTVMLVSIDGEAAGLVAVADTIKDTSRKAVARL
KELGLDVIMMTGDNRRTAEAIAKEAGIANIIAEVLPEQKAAEIARLQKEGRQTAMVGDGINDAPALATADIGMAIGTGTD
IAMETADITLIRGDLNSIADAIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIAGAAMAFSSVSVVLNALRLQK
VK
>Mature_801_residues
SEQKEIAMQVSGMTCAACAARIEKGLKRMPGVTDANVNLATETSNVIYDPAETGTAAIQEKIEKLGYHVVTEKAEFDIEG
MTCAACANRIEKRLNKIEGVANAPVNFALETVTVEYNPKEASVSDLKEAVDKLGYKLKLKGEQDSEAAAKKKEERKQTAR
LIFSAVLSFPLLWAMVSHFTFTSFIWVPDIFLNPWMQFALATPVQFLIGWPFYVGAYKALRNKSANMDVLVALGTTAAYA
YSLYLTFQSIGSHGHTDGLYYETSAILLTLILLGKLFETKAKGRSSDAIKKLMKLQAKTATVVRDGQEQIIPIDEVLVND
IVYVKPGERIPVDGEVVEGRSAVDESMITGESLPVDKNPGDSVTGSTVNANGFLKIKAVNVGKDTALSHIIKIVEEAQGS
KAPIQRLADQISGIFVPIVLGIAVLTFLIWYLWAAPGDFAEAISKFIAVLVIACPCALGLATPTSIMAGSGRAAEFGILF
KGGEHLEKTHRLDTIVLDKTGTVTNGKPRLTDAIPFGRFEEKDLLQFAAAAETGSEHPLGEAIIAGVKDKGLEIPKLTRF
EAKVGAGILAEAGGKSILVGTRKLMESEQVEHGALLAQMEELEAEGKTVMLVSIDGEAAGLVAVADTIKDTSRKAVARLK
ELGLDVIMMTGDNRRTAEAIAKEAGIANIIAEVLPEQKAAEIARLQKEGRQTAMVGDGINDAPALATADIGMAIGTGTDI
AMETADITLIRGDLNSIADAIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIAGAAMAFSSVSVVLNALRLQKV
K

Specific function: Involved in copper export

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains

Homologues:

Organism=Homo sapiens, GI55743071, Length=863, Percent_Identity=38.5863267670915, Blast_Score=563, Evalue=1e-160,
Organism=Homo sapiens, GI115529486, Length=898, Percent_Identity=37.3051224944321, Blast_Score=536, Evalue=1e-152,
Organism=Homo sapiens, GI55743073, Length=839, Percent_Identity=33.611442193087, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI48762685, Length=183, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI48762689, Length=183, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI48762691, Length=183, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI48762687, Length=183, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI28373107, Length=174, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI28373115, Length=174, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI28373111, Length=174, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI28373109, Length=174, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI28373105, Length=174, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI28373113, Length=174, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI28373103, Length=174, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI83700225, Length=256, Percent_Identity=27.734375, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI237681109, Length=306, Percent_Identity=24.8366013071895, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI21361181, Length=306, Percent_Identity=24.8366013071895, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI237681111, Length=306, Percent_Identity=24.8366013071895, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI118498343, Length=168, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI10835220, Length=201, Percent_Identity=28.3582089552239, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI27886529, Length=201, Percent_Identity=28.3582089552239, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI209413709, Length=201, Percent_Identity=28.8557213930348, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI24638454, Length=201, Percent_Identity=28.8557213930348, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4502285, Length=201, Percent_Identity=28.8557213930348, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI51944966, Length=266, Percent_Identity=29.3233082706767, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI4502271, Length=353, Percent_Identity=23.2294617563739, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI22748667, Length=266, Percent_Identity=24.812030075188, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI297374799, Length=228, Percent_Identity=28.0701754385965, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310128958, Length=195, Percent_Identity=29.2307692307692, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI153946397, Length=226, Percent_Identity=26.5486725663717, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1786691, Length=853, Percent_Identity=39.6248534583822, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI1789879, Length=762, Percent_Identity=33.2020997375328, Blast_Score=349, Evalue=4e-97,
Organism=Escherichia coli, GI1786914, Length=501, Percent_Identity=32.5349301397206, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI2367363, Length=634, Percent_Identity=24.2902208201893, Blast_Score=126, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17556548, Length=876, Percent_Identity=36.4155251141553, Blast_Score=485, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17559224, Length=307, Percent_Identity=26.7100977198697, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17554158, Length=201, Percent_Identity=29.3532338308458, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71988506, Length=201, Percent_Identity=29.3532338308458, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193210130, Length=201, Percent_Identity=29.3532338308458, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32566766, Length=190, Percent_Identity=27.8947368421053, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17557486, Length=195, Percent_Identity=27.6923076923077, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17557770, Length=190, Percent_Identity=27.8947368421053, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17531459, Length=160, Percent_Identity=30.625, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71997269, Length=278, Percent_Identity=25.8992805755396, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997275, Length=184, Percent_Identity=29.8913043478261, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997262, Length=278, Percent_Identity=25.8992805755396, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=867, Percent_Identity=35.4094579008074, Blast_Score=457, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6319772, Length=643, Percent_Identity=31.5707620528771, Blast_Score=287, Evalue=4e-78,
Organism=Saccharomyces cerevisiae, GI6321430, Length=553, Percent_Identity=27.4864376130199, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6325221, Length=576, Percent_Identity=25.8680555555556, Blast_Score=137, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6321271, Length=184, Percent_Identity=32.0652173913043, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321432, Length=211, Percent_Identity=29.8578199052133, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6320243, Length=287, Percent_Identity=27.1777003484321, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320244, Length=287, Percent_Identity=27.1777003484321, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320245, Length=287, Percent_Identity=27.1777003484321, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221329854, Length=616, Percent_Identity=35.5519480519481, Blast_Score=343, Evalue=2e-94,
Organism=Drosophila melanogaster, GI17136664, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762455, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762453, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762447, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762457, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762449, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762445, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762451, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45553435, Length=306, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45553437, Length=306, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45553439, Length=306, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45553441, Length=306, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648580, Length=306, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648578, Length=306, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281362164, Length=306, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648576, Length=306, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281366676, Length=195, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24648582, Length=306, Percent_Identity=24.5098039215686, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24668708, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281366617, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668704, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24668696, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161085803, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COPA_BACSU (O32220)

Other databases:

- EMBL:   AL009126
- PIR:   E70041
- RefSeq:   NP_391230.2
- PDB:   1JWW
- PDB:   1KQK
- PDB:   1OPZ
- PDB:   1OQ3
- PDB:   1OQ6
- PDB:   1P6T
- PDB:   2RML
- PDBsum:   1JWW
- PDBsum:   1KQK
- PDBsum:   1OPZ
- PDBsum:   1OQ3
- PDBsum:   1OQ6
- PDBsum:   1P6T
- PDBsum:   2RML
- ProteinModelPortal:   O32220
- IntAct:   O32220
- EnsemblBacteria:   EBBACT00000003365
- GeneID:   937985
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33500
- NMPDR:   fig|224308.1.peg.3356
- GenoList:   BSU33500
- GeneTree:   EBGT00070000031791
- HOGENOM:   HBG507745
- ProtClustDB:   CLSK2539634
- BioCyc:   BSUB:BSU33500-MONOMER
- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR006122
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- Gene3D:   G3DSA:3.40.50.1000
- PANTHER:   PTHR11939
- PRINTS:   PR00119
- PRINTS:   PR00943
- PRINTS:   PR00942
- TIGRFAMs:   TIGR01511
- TIGRFAMs:   TIGR01525
- TIGRFAMs:   TIGR01494
- TIGRFAMs:   TIGR00003

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase; SSF55008 HeavyMe_transpt; SSF56784 SSF56784

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 85912; Mature: 85781

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00154 ATPASE_E1_E2; PS01047 HMA_1; PS50846 HMA_2

Important sites: ACT_SITE 499-499

Signals:

None

Transmembrane regions:

HASH(0x10cf35cc)-; HASH(0x1264d008)-; HASH(0x124b95ec)-; HASH(0x1244d940)-; HASH(0x123cafd0)-; HASH(0x11a62d38)-; HASH(0x11db32a0)-; HASH(0x1226d0e4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQKEIAMQVSGMTCAACAARIEKGLKRMPGVTDANVNLATETSNVIYDPAETGTAAIQ
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEECCCCCCHHHHH
EKIEKLGYHVVTEKAEFDIEGMTCAACANRIEKRLNKIEGVANAPVNFALETVTVEYNPK
HHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCC
EASVSDLKEAVDKLGYKLKLKGEQDSEAAAKKKEERKQTARLIFSAVLSFPLLWAMVSHF
CCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFTSFIWVPDIFLNPWMQFALATPVQFLIGWPFYVGAYKALRNKSANMDVLVALGTTAAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCHHHH
AYSLYLTFQSIGSHGHTDGLYYETSAILLTLILLGKLFETKAKGRSSDAIKKLMKLQAKT
HHHHEEEHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ATVVRDGQEQIIPIDEVLVNDIVYVKPGERIPVDGEVVEGRSAVDESMITGESLPVDKNP
HHHHCCCCHHCCCHHHHHHCCEEEECCCCCCCCCCCEECCHHHHHHHHHCCCCCCCCCCC
GDSVTGSTVNANGFLKIKAVNVGKDTALSHIIKIVEEAQGSKAPIQRLADQISGIFVPIV
CCCCCCCEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
LGIAVLTFLIWYLWAAPGDFAEAISKFIAVLVIACPCALGLATPTSIMAGSGRAAEFGIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEEE
FKGGEHLEKTHRLDTIVLDKTGTVTNGKPRLTDAIPFGRFEEKDLLQFAAAAETGSEHPL
ECCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
GEAIIAGVKDKGLEIPKLTRFEAKVGAGILAEAGGKSILVGTRKLMESEQVEHGALLAQM
CHHHHHCCCCCCCCCCCCHHHHHHHCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHH
EELEAEGKTVMLVSIDGEAAGLVAVADTIKDTSRKAVARLKELGLDVIMMTGDNRRTAEA
HHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHH
IAKEAGIANIIAEVLPEQKAAEIARLQKEGRQTAMVGDGINDAPALATADIGMAIGTGTD
HHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECCCCEEECCCCC
IAMETADITLIRGDLNSIADAIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIA
CEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
GAAMAFSSVSVVLNALRLQKVK
HHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SEQKEIAMQVSGMTCAACAARIEKGLKRMPGVTDANVNLATETSNVIYDPAETGTAAIQ
CCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEECCCCCCHHHHH
EKIEKLGYHVVTEKAEFDIEGMTCAACANRIEKRLNKIEGVANAPVNFALETVTVEYNPK
HHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCC
EASVSDLKEAVDKLGYKLKLKGEQDSEAAAKKKEERKQTARLIFSAVLSFPLLWAMVSHF
CCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFTSFIWVPDIFLNPWMQFALATPVQFLIGWPFYVGAYKALRNKSANMDVLVALGTTAAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCHHHH
AYSLYLTFQSIGSHGHTDGLYYETSAILLTLILLGKLFETKAKGRSSDAIKKLMKLQAKT
HHHHEEEHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ATVVRDGQEQIIPIDEVLVNDIVYVKPGERIPVDGEVVEGRSAVDESMITGESLPVDKNP
HHHHCCCCHHCCCHHHHHHCCEEEECCCCCCCCCCCEECCHHHHHHHHHCCCCCCCCCCC
GDSVTGSTVNANGFLKIKAVNVGKDTALSHIIKIVEEAQGSKAPIQRLADQISGIFVPIV
CCCCCCCEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
LGIAVLTFLIWYLWAAPGDFAEAISKFIAVLVIACPCALGLATPTSIMAGSGRAAEFGIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEEE
FKGGEHLEKTHRLDTIVLDKTGTVTNGKPRLTDAIPFGRFEEKDLLQFAAAAETGSEHPL
ECCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
GEAIIAGVKDKGLEIPKLTRFEAKVGAGILAEAGGKSILVGTRKLMESEQVEHGALLAQM
CHHHHHCCCCCCCCCCCCHHHHHHHCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHH
EELEAEGKTVMLVSIDGEAAGLVAVADTIKDTSRKAVARLKELGLDVIMMTGDNRRTAEA
HHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHH
IAKEAGIANIIAEVLPEQKAAEIARLQKEGRQTAMVGDGINDAPALATADIGMAIGTGTD
HHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCEECCCCEEECCCCC
IAMETADITLIRGDLNSIADAIRMSRLTMKNIKQNLFWALGYNSLGIPIAALGFLAPWIA
CEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
GAAMAFSSVSVVLNALRLQKVK
HHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12644235; 11922674; 12590580