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The map label for this gene is rsbRD

Identifier: 255767554

GI number: 255767554

Start: 2562966

End: 2563802

Strand: Reverse

Name: rsbRD

Synonym: BSU24760

Alternate gene names: 255767554

Gene position: 2563802-2562966 (Counterclockwise)

Preceding gene: 255767555

Following gene: 16079530

Centisome position: 60.82

GC content: 41.82

Gene sequence:

>837_bases
ATGATAGCTCTTGATCAGCACTTAACAGAGCACAAAAAAGATATTACGCAACAATGGCTGGAAGTTTGTACGTCAAACGG
CAGCTGGCTGTATTCAGCGAAAGATCAGCAAAAACTAGAACAAAAGTTAAAAGACCAGCATGAATTATTGGTGACCATCG
TAGCAAAATCCCTTAGAAAAGAAGACGTAGAGGATGAGCTCAACCGGTGGTCTCTTCAATGCGCCAGAGACCGTGCCGTT
CATGAAGTGACGGTTACACAAAGTGTCGGCCAGTTTAACACTTTCAGGCACATCATGTTTGAATGGATTCATAAATTCAG
CGAAGCTTCTTCTCAAGACATCAGCATTCAGGAATTTTATGAGTGGAGCCGGATCTTGAATCAAAACATTGATGAGATCA
TCGAAGTGTTTACGGAAGAATATCACCAGGTGACCATGATACAATTAAACGCGCAAAAAGAAATGATTAATGAATTGAGT
GCGCCGATTATGCCGATTACTGATGGAATTGGGATTCTTCCGCTTGTCGGTGAAATTGATACGCACAGAGCGAGGACGAT
TTTGGAGTCTGTGCTGGAGCAGTGCTCAGCGTTAAAGCTCTCGTATTTATTTTTAGATATTTCGGGCGTTCCTATCGTTG
ATACCATGGTAGCCTATCAAATTTTTAAAGTGATTGACAGCACCAAATTGCTCGGCATTGAGACTATTATTTCAGGAATC
AGGCCGGAAATTGCCCAAACTGTCGTGAAGCTGGGTCTGGATTTTTCGAATGTGAAAACAGAGCAAAGTCTTGCTAAAGC
CCTGGCCAATAAAGGGTTTAAAATAAAAGAGTGTTGA

Upstream 100 bases:

>100_bases
TTGGCTATAGCCCATTGAATCTAAACATAGTATGTGTAAAGGCAGACGCGTTATACATATATAGCGTACATTTTTCAAAA
ACAGGAGGTAACTCATTAAG

Downstream 100 bases:

>100_bases
TGCCTTTGCCATGTTTATCTTGAAAGATAGCAGCTGAACAGCCTTTCACGGGCTATTCAGCTTTTTTAACTTCTATAAAT
AAAATGTGATGGCTGTTGAT

Product: piezosome protein

Products: NA

Alternate protein names: Stressosome protein rsbRD

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MIALDQHLTEHKKDITQQWLEVCTSNGSWLYSAKDQQKLEQKLKDQHELLVTIVAKSLRKEDVEDELNRWSLQCARDRAV
HEVTVTQSVGQFNTFRHIMFEWIHKFSEASSQDISIQEFYEWSRILNQNIDEIIEVFTEEYHQVTMIQLNAQKEMINELS
APIMPITDGIGILPLVGEIDTHRARTILESVLEQCSALKLSYLFLDISGVPIVDTMVAYQIFKVIDSTKLLGIETIISGI
RPEIAQTVVKLGLDFSNVKTEQSLAKALANKGFKIKEC

Sequences:

>Translated_278_residues
MIALDQHLTEHKKDITQQWLEVCTSNGSWLYSAKDQQKLEQKLKDQHELLVTIVAKSLRKEDVEDELNRWSLQCARDRAV
HEVTVTQSVGQFNTFRHIMFEWIHKFSEASSQDISIQEFYEWSRILNQNIDEIIEVFTEEYHQVTMIQLNAQKEMINELS
APIMPITDGIGILPLVGEIDTHRARTILESVLEQCSALKLSYLFLDISGVPIVDTMVAYQIFKVIDSTKLLGIETIISGI
RPEIAQTVVKLGLDFSNVKTEQSLAKALANKGFKIKEC
>Mature_278_residues
MIALDQHLTEHKKDITQQWLEVCTSNGSWLYSAKDQQKLEQKLKDQHELLVTIVAKSLRKEDVEDELNRWSLQCARDRAV
HEVTVTQSVGQFNTFRHIMFEWIHKFSEASSQDISIQEFYEWSRILNQNIDEIIEVFTEEYHQVTMIQLNAQKEMINELS
APIMPITDGIGILPLVGEIDTHRARTILESVLEQCSALKLSYLFLDISGVPIVDTMVAYQIFKVIDSTKLLGIETIISGI
RPEIAQTVVKLGLDFSNVKTEQSLAKALANKGFKIKEC

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSBRD_BACSU (P54504)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   D69958
- RefSeq:   NP_390356.2
- ProteinModelPortal:   P54504
- SMR:   P54504
- PhosSite:   P54504
- EnsemblBacteria:   EBBACT00000003557
- GeneID:   938513
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU24760
- NMPDR:   fig|224308.1.peg.2480
- GenoList:   BSU24760
- GeneTree:   EBGT00050000000143
- HOGENOM:   HBG338610
- ProtClustDB:   CLSK887569
- BioCyc:   BSUB:BSU24760-MONOMER
- InterPro:   IPR002645
- Gene3D:   G3DSA:3.30.750.24

Pfam domain/function: PF01740 STAS; SSF52091 STAS

EC number: NA

Molecular weight: Translated: 31835; Mature: 31835

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALDQHLTEHKKDITQQWLEVCTSNGSWLYSAKDQQKLEQKLKDQHELLVTIVAKSLRK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDVEDELNRWSLQCARDRAVHEVTVTQSVGQFNTFRHIMFEWIHKFSEASSQDISIQEFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
EWSRILNQNIDEIIEVFTEEYHQVTMIQLNAQKEMINELSAPIMPITDGIGILPLVGEID
HHHHHHHCCHHHHHHHHHHHHHHEEEEEECHHHHHHHHHCCCCEECCCCCCHHHHHCCCH
THRARTILESVLEQCSALKLSYLFLDISGVPIVDTMVAYQIFKVIDSTKLLGIETIISGI
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPEIAQTVVKLGLDFSNVKTEQSLAKALANKGFKIKEC
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure
MIALDQHLTEHKKDITQQWLEVCTSNGSWLYSAKDQQKLEQKLKDQHELLVTIVAKSLRK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDVEDELNRWSLQCARDRAVHEVTVTQSVGQFNTFRHIMFEWIHKFSEASSQDISIQEFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
EWSRILNQNIDEIIEVFTEEYHQVTMIQLNAQKEMINELSAPIMPITDGIGILPLVGEID
HHHHHHHCCHHHHHHHHHHHHHHEEEEEECHHHHHHHHHCCCCEECCCCCCHHHHHCCCH
THRARTILESVLEQCSALKLSYLFLDISGVPIVDTMVAYQIFKVIDSTKLLGIETIISGI
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPEIAQTVVKLGLDFSNVKTEQSLAKALANKGFKIKEC
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 11157946