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The map label for this gene is yoeA

Identifier: 255767430

GI number: 255767430

Start: 2000960

End: 2002351

Strand: Reverse

Name: yoeA

Synonym: BSU18370

Alternate gene names: 255767430

Gene position: 2002351-2000960 (Counterclockwise)

Preceding gene: 255767432

Following gene: 16078897

Centisome position: 47.5

GC content: 44.04

Gene sequence:

>1392_bases
ATGGAAACATCACAAGAACCTCTTGTAACTCAAAAGAAAAGCAAACCATCAGTTTGGCGGTCGATGTCACTCTTTTTAGT
GCCGCTTCTGCTGAGCAATGTGCTGCAATCAGTCGGCCAGCTAGTCGGGATGATGGCTGTAGGCAGATGGCTCGGTGTTG
ATGCAGTGGCAGCTGTATCATCCTTTTTCCCGTTATTTTTTCTTTTAATCTCATTTACGATTGGGATCGGTTCAGGAAGT
TCGATTCTGATAGGACAAGCTTACGGAGCGAAAAATGAGGAACGGCTAAAGGCTGTTGTCGGGACGACACTCACGTTTAC
ATTTTTATTAGGCGTTGTGTTAGCCGTTATCGGCAGTATTTTCACCCTGGATATCCTTCGTTTAATGGGAACACCTGAAA
ATGTCATTCATGTCAGCGCTAACTATGCACGTATTTTATTTTATGCTATGCCGTTTATGTTTTTATATTTTGCATATACT
ACCTTTTTGCGCGGAACAGGAGATTCCAAGACACCGTTTTATACGCTGATTGTGAGCACGGTCATCAACATCGCGCTTTT
GCCTGTTTTAATCCTTGGCATGTTTGGTTTTCCGAAACTGGGCATATACGGCTCGGCATATGCAACTGTCATTTCCACGA
TTGCGACTTTTCTCGTGTTAATGGTGTATTTACGAAAGCGAAAACACCCGCTGCAATTTGATAAAACAGTGCGTCGTTAT
TTGAAAATGGATAAGGAACTGCTGGTTCTCCTGCTGCGTCTTGGGGTCCCAGCAAGCATCAATATGATTCTTGTCTCATT
ATCAGAGATAGCGGTTATTTCATTCGTCAATCATTACGGCTCTAATGCAACAGCTGCATACGGAGTGGTCAACCAGGTGG
CCAGCTATGTACAGATGCCGGCCGTCAGCCTTGGTATTGCGGTTTCTATTTTCGCTGCGCAATCGATCGGAGCAAACGAG
TTTGACCGCTTAAAGCAGGTCATTCGCGTTGGGATTTGGCTGAATTATATCATTGGCGGCGTACTGATCATTCTGATCTA
TGTTTTTTCACATCAGATTTTATCGTTATTTTTAACCGAGCAAGAGACGCTTTACATTGCGCACCGTCTTTTGATGATTA
CACTGTGGAGCTATTTGCTGTTTGGAAATGCCCAAATTATTTCTGCAACGATGCGGGCAAGCGGAACAGTTTTATGGCCG
ACCGTCATCAGTATTTTTGCAATCTGGGGAGTAGAGGTGCCTGTCGCTTTCGTCCTTTCTCACTATACAAAGCTTGAAAT
ACTCGGCGTCTGGGTTGGTTATCCAGCTGCGTTTGCCGTCAGCTTGCTGTTGATTTATGGGTATTATCAATTCGTCTGGA
AAAAGAAACAAATCACACGTCTCATCCAATAG

Upstream 100 bases:

>100_bases
TCATAAGTGCAGTGATGAATAATAACATGTTACATATCCTGTTTTTGTCAAAAAATGAGGGCATGTTTAAAAACGATTTC
AAATAAAGGAGTCCTTTAAT

Downstream 100 bases:

>100_bases
CCTCCGAATCACACCGTTCATAAGTTTGAACGGTGTTTTTTTATTTGATAGGGGAAAATATAAAATGGAGGAAATATGGT
ACAGTACATTGAATTCTTAT

Product: efflux transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMMAVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGS
SILIGQAYGAKNEERLKAVVGTTLTFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYT
TFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMVYLRKRKHPLQFDKTVRRY
LKMDKELLVLLLRLGVPASINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANE
FDRLKQVIRVGIWLNYIIGGVLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLWP
TVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQITRLIQ

Sequences:

>Translated_463_residues
METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMMAVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGS
SILIGQAYGAKNEERLKAVVGTTLTFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYT
TFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMVYLRKRKHPLQFDKTVRRY
LKMDKELLVLLLRLGVPASINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANE
FDRLKQVIRVGIWLNYIIGGVLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLWP
TVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQITRLIQ
>Mature_463_residues
METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMMAVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGS
SILIGQAYGAKNEERLKAVVGTTLTFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYT
TFLRGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMVYLRKRKHPLQFDKTVRRY
LKMDKELLVLLLRLGVPASINMILVSLSEIAVISFVNHYGSNATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANE
FDRLKQVIRVGIWLNYIIGGVLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLWP
TVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQITRLIQ

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family

Homologues:

Organism=Escherichia coli, GI226510954, Length=443, Percent_Identity=21.4446952595937, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321821, Length=299, Percent_Identity=25.4180602006689, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YOEA_BACSU (O34474)

Other databases:

- EMBL:   AL009126
- PIR:   A69905
- RefSeq:   NP_389719.2
- EnsemblBacteria:   EBBACT00000000981
- GeneID:   939596
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU18370
- NMPDR:   fig|224308.1.peg.1841
- GenoList:   BSU18370
- GeneTree:   EBGT00050000000379
- HOGENOM:   HBG458967
- ProtClustDB:   CLSK887369
- BioCyc:   BSUB:BSU18370-MONOMER
- InterPro:   IPR002528
- InterPro:   IPR015522
- PANTHER:   PTHR11206
- PANTHER:   PTHR11206:SF6
- TIGRFAMs:   TIGR00797

Pfam domain/function: PF01554 MatE

EC number: NA

Molecular weight: Translated: 51306; Mature: 51306

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf52f658)-; HASH(0xfaeed00)-; HASH(0xf66e3f0)-; HASH(0xf6432ec)-; HASH(0xf8403d0)-; HASH(0xf1d8dc8)-; HASH(0xf883390)-; HASH(0xfb426cc)-; HASH(0xe4ad28c)-; HASH(0xfdf5808)-; HASH(0xfdfdfb4)-; HASH(0xfaf1118)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure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HHHHHHHEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377