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The map label for this gene is ftsA

Identifier: 255767352

GI number: 255767352

Start: 1596474

End: 1597796

Strand: Direct

Name: ftsA

Synonym: BSU15280

Alternate gene names: 255767352

Gene position: 1596474-1597796 (Clockwise)

Preceding gene: 16078591

Following gene: 255767353

Centisome position: 37.87

GC content: 43.46

Gene sequence:

>1323_bases
ATGAACAACAATGAACTTTACGTCAGTCTTGACATCGGTACGTCCAATACAAAAGTGATCGTCGGAGAAATGACAGATGA
TTCCCTTAATATTATCGGTGTGGGAAATGTACCGTCTGAAGGGTTGAAAAAAGGCTCAATCGTTGATATAGATGAGACCG
TTCATTCTATAAGAAAAGCGTTTGACCAAGCTGAAAGAATGGTAGGTTTTCCGCTTAGAAAAGCTATTGTCGGCGTTAAT
GGAAATTATATCAATATTCAAGATACAAACGGTGTTGTAGCAGTTTCCAGTGAAAATAAAGAAATTCAGGTTGAAGATGT
ACGCCGTGTCATGGAGGCGGCACAGGTTGTTTCCGTACCGCATGAACAGCTGATTGTTGACGTCATTCCTAAACAGTTTA
TCGTAGATGGAAGAGATGAAATCACCGACCCGAAAAAAATGCTGGGTGTGCGTTTAGAAGTAGAGGGCACCTTGATCACC
GGTTCAAAAACAATCTTACATAACTTACTCCGCTGCGTTGAAAGAGCTGGTATTGAAATAACTGATATTTGCCTTCAGCC
GCTGGCAGCCGGTTCTGCTGCATTATCAAAGGACGAGAAAAACCTTGGTGTGGCTCTCATTGATATAGGGGGAGGGTCAA
CAACCATTGCCGTATTCCAGAACGGACATCTCACTTCTACCCGTGTCATTCCTCTCGGAGGCGAAAATATCACCAAAGAT
ATCTCCATCGGATTGAGAACGTCAACAGAAGAAGCAGAACGCGTGAAAAAGCAACTTGGACATGCCTACTATGACGAAGC
CTCGGAAGATGAAATATTTGAGGTAACCGTTATAGGCACCAATCAAAAACAAACATTTACACAGCAAGAAGCAGCGAATA
TCATTGAAGCGAGAGTAGAGGAAATTCTTGAAATTGTTTCAGAAGAGCTTCGCAGTATGGGAATTACCGATCTGCCGGGA
GGCTTCGTGCTGACAGGAGGACAAGCAGCTATGCCGGGTGTCATGTCTTTGGCACAGGATGTGCTGCAAAACAATGTCAG
AGTGGCAAGCCCGAATTATATCGGTGTAAGAGATCCTCAATATATGACGGGAGTGGGCCTGATCCAATTCGCCTGCCGGA
ATGCAAGAATCCAAGGCAGAAAAATAGGCTTTAAGATGCCTGAAGAAGCGATACAGGAAATCGCAGTCTCATCATCTGAG
GAACAAGAGCAGCATCATCACCAAAATGAGGTGCAGCAGCGGCCAAAAGGAAAACAAAAAACACAAGCCGAACATAATAA
ACAGAGCAAAATGAAAAAACTATTAAGCATGTTTTGGGAATAG

Upstream 100 bases:

>100_bases
TTGTTATTTTTTGTTACACACTTGTAAAGCCACATTCATTGTATTGTTGTTCCGCAAATAATAGAATAGAAATGATCGAA
ATGTGAGGAGGTGCCATAGA

Downstream 100 bases:

>100_bases
ATAGATAGTCATTCGGCAGATTAGGAGGATTTAGCATGTTGGAGTTCGAAACAAACATAGACGGCTTAGCATCAATTAAA
GTAATCGGAGTAGGAGGCGG

Product: cell-division protein essential fo Z-ring assembly

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNNNELYVSLDIGTSNTKVIVGEMTDDSLNIIGVGNVPSEGLKKGSIVDIDETVHSIRKAFDQAERMVGFPLRKAIVGVN
GNYINIQDTNGVVAVSSENKEIQVEDVRRVMEAAQVVSVPHEQLIVDVIPKQFIVDGRDEITDPKKMLGVRLEVEGTLIT
GSKTILHNLLRCVERAGIEITDICLQPLAAGSAALSKDEKNLGVALIDIGGGSTTIAVFQNGHLTSTRVIPLGGENITKD
ISIGLRTSTEEAERVKKQLGHAYYDEASEDEIFEVTVIGTNQKQTFTQQEAANIIEARVEEILEIVSEELRSMGITDLPG
GFVLTGGQAAMPGVMSLAQDVLQNNVRVASPNYIGVRDPQYMTGVGLIQFACRNARIQGRKIGFKMPEEAIQEIAVSSSE
EQEQHHHQNEVQQRPKGKQKTQAEHNKQSKMKKLLSMFWE

Sequences:

>Translated_440_residues
MNNNELYVSLDIGTSNTKVIVGEMTDDSLNIIGVGNVPSEGLKKGSIVDIDETVHSIRKAFDQAERMVGFPLRKAIVGVN
GNYINIQDTNGVVAVSSENKEIQVEDVRRVMEAAQVVSVPHEQLIVDVIPKQFIVDGRDEITDPKKMLGVRLEVEGTLIT
GSKTILHNLLRCVERAGIEITDICLQPLAAGSAALSKDEKNLGVALIDIGGGSTTIAVFQNGHLTSTRVIPLGGENITKD
ISIGLRTSTEEAERVKKQLGHAYYDEASEDEIFEVTVIGTNQKQTFTQQEAANIIEARVEEILEIVSEELRSMGITDLPG
GFVLTGGQAAMPGVMSLAQDVLQNNVRVASPNYIGVRDPQYMTGVGLIQFACRNARIQGRKIGFKMPEEAIQEIAVSSSE
EQEQHHHQNEVQQRPKGKQKTQAEHNKQSKMKKLLSMFWE
>Mature_440_residues
MNNNELYVSLDIGTSNTKVIVGEMTDDSLNIIGVGNVPSEGLKKGSIVDIDETVHSIRKAFDQAERMVGFPLRKAIVGVN
GNYINIQDTNGVVAVSSENKEIQVEDVRRVMEAAQVVSVPHEQLIVDVIPKQFIVDGRDEITDPKKMLGVRLEVEGTLIT
GSKTILHNLLRCVERAGIEITDICLQPLAAGSAALSKDEKNLGVALIDIGGGSTTIAVFQNGHLTSTRVIPLGGENITKD
ISIGLRTSTEEAERVKKQLGHAYYDEASEDEIFEVTVIGTNQKQTFTQQEAANIIEARVEEILEIVSEELRSMGITDLPG
GFVLTGGQAAMPGVMSLAQDVLQNNVRVASPNYIGVRDPQYMTGVGLIQFACRNARIQGRKIGFKMPEEAIQEIAVSSSE
EQEQHHHQNEVQQRPKGKQKTQAEHNKQSKMKKLLSMFWE

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family

Homologues:

Organism=Escherichia coli, GI1786282, Length=383, Percent_Identity=35.509138381201, Blast_Score=234, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSA_BACSU (P28264)

Other databases:

- EMBL:   M22630
- EMBL:   AL009126
- EMBL:   X66239
- EMBL:   S39431
- PIR:   I39847
- RefSeq:   NP_389411.2
- ProteinModelPortal:   P28264
- SMR:   P28264
- IntAct:   P28264
- EnsemblBacteria:   EBBACT00000003860
- GeneID:   936145
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU15280
- NMPDR:   fig|224308.1.peg.1530
- GenoList:   BSU15280
- GeneTree:   EBGT00050000001172
- HOGENOM:   HBG616668
- ProtClustDB:   CLSK2460919
- BioCyc:   BSUB:BSU15280-MONOMER
- InterPro:   IPR020823
- InterPro:   IPR003494
- SMART:   SM00842
- TIGRFAMs:   TIGR01174

Pfam domain/function: PF02491 FtsA

EC number: NA

Molecular weight: Translated: 48193; Mature: 48193

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNELYVSLDIGTSNTKVIVGEMTDDSLNIIGVGNVPSEGLKKGSIVDIDETVHSIRKA
CCCCEEEEEEEECCCCCEEEEEEECCCCEEEEEECCCCHHHCCCCCEEEHHHHHHHHHHH
FDQAERMVGFPLRKAIVGVNGNYINIQDTNGVVAVSSENKEIQVEDVRRVMEAAQVVSVP
HHHHHHHHCCCHHHHEEECCCCEEEEECCCCEEEEECCCCEEEHHHHHHHHHHHHHHHCC
HEQLIVDVIPKQFIVDGRDEITDPKKMLGVRLEVEGTLITGSKTILHNLLRCVERAGIEI
HHHHHHHHCCHHHEECCCHHCCCHHHHHEEEEEEEEEEEECCHHHHHHHHHHHHHCCCEE
TDICLQPLAAGSAALSKDEKNLGVALIDIGGGSTTIAVFQNGHLTSTRVIPLGGENITKD
EHHHHHHHHCCCHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCCE
ISIGLRTSTEEAERVKKQLGHAYYDEASEDEIFEVTVIGTNQKQTFTQQEAANIIEARVE
EEEEECCCHHHHHHHHHHHCHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHH
EILEIVSEELRSMGITDLPGGFVLTGGQAAMPGVMSLAQDVLQNNVRVASPNYIGVRDPQ
HHHHHHHHHHHHCCCCCCCCCEEEECCCHHCHHHHHHHHHHHHCCCEEECCCEECCCCCC
YMTGVGLIQFACRNARIQGRKIGFKMPEEAIQEIAVSSSEEQEQHHHQNEVQQRPKGKQK
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHH
TQAEHNKQSKMKKLLSMFWE
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNNELYVSLDIGTSNTKVIVGEMTDDSLNIIGVGNVPSEGLKKGSIVDIDETVHSIRKA
CCCCEEEEEEEECCCCCEEEEEEECCCCEEEEEECCCCHHHCCCCCEEEHHHHHHHHHHH
FDQAERMVGFPLRKAIVGVNGNYINIQDTNGVVAVSSENKEIQVEDVRRVMEAAQVVSVP
HHHHHHHHCCCHHHHEEECCCCEEEEECCCCEEEEECCCCEEEHHHHHHHHHHHHHHHCC
HEQLIVDVIPKQFIVDGRDEITDPKKMLGVRLEVEGTLITGSKTILHNLLRCVERAGIEI
HHHHHHHHCCHHHEECCCHHCCCHHHHHEEEEEEEEEEEECCHHHHHHHHHHHHHCCCEE
TDICLQPLAAGSAALSKDEKNLGVALIDIGGGSTTIAVFQNGHLTSTRVIPLGGENITKD
EHHHHHHHHCCCHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCCE
ISIGLRTSTEEAERVKKQLGHAYYDEASEDEIFEVTVIGTNQKQTFTQQEAANIIEARVE
EEEEECCCHHHHHHHHHHHCHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHH
EILEIVSEELRSMGITDLPGGFVLTGGQAAMPGVMSLAQDVLQNNVRVASPNYIGVRDPQ
HHHHHHHHHHHHCCCCCCCCCEEEECCCHHCHHHHHHHHHHHHCCCEEECCCEECCCCCC
YMTGVGLIQFACRNARIQGRKIGFKMPEEAIQEIAVSSSEEQEQHHHQNEVQQRPKGKQK
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHH
TQAEHNKQSKMKKLLSMFWE
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3139638; 9384377; 1569582; 1624452