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The map label for this gene is ctaD

Identifier: 255767339

GI number: 255767339

Start: 1561569

End: 1563437

Strand: Direct

Name: ctaD

Synonym: BSU14900

Alternate gene names: 255767339

Gene position: 1561569-1563437 (Clockwise)

Preceding gene: 16078553

Following gene: 16078555

Centisome position: 37.04

GC content: 47.57

Gene sequence:

>1869_bases
ATGTTGAATGCGCTTACAGAAAAGCGGACGCGCGGATCTATGCTTTGGGATTATTTGACGACGGTGGACCATAAAAAAAT
CGCAATTCTTTATTTAGTGGCAGGGGGATTCTTCTTTCTTGTCGGGGGAATTGAAGCGATGTTTATCAGAATTCAGCTTG
CAAAGCCGGAAAATGCGTTTCTCAGTGCTCAAGCGTACAATGAAGTAATGACTATGCACGGAACGACGATGATCTTTCTG
GCTGCGATGCCGCTCTTATTTGCCTTGATGAATGCGGTTGTGCCTTTGCAGATCGGGGCTCGGGACGTTTCGTTTCCATT
TTTAAACGCGCTTGGTTTTTGGCTCTTCTTTTTCGGGGGCATTTTCTTAAATCTAAGCTGGTTTTTGGGCGGAGCGCCAG
ATGCGGGCTGGACATCATATGCCTCACTTTCGCTTCATTCTAAAGGGCACGGCATAGACTTTTTCGTCCTCGGACTCCAA
ATATCGGGGCTCGGGACGCTGATAGCCGGGATTAACTTTTTGGCCACGATTATCAACATGAGGGCTCCGGGCATGACGTA
TATGAGGCTGCCTTTGTTTACATGGACGACATTTGTGGCCTCGGCATTGATTTTGTTCGCGTTTCCGCCGCTTACGGTTG
GATTGGCTCTCATGATGCTGGATCGGCTGTTCGGAACCAATTTCTTTAATCCGGAGCTTGGCGGAAATACGGTCATTTGG
GAACATTTATTTTGGATCTTCGGCCACCCGGAGGTTTATATCCTAATTTTGCCTGCATTCGGTATTTTTTCTGAGGTCAT
CCCTGTGTTCGCCAGAAAGCGTTTGTTTGGCTATTCTTCAATGGTTTTTGCAATCGTGCTCATTGGCTTTCTGGGCTTTA
TGGTTTGGGTGCACCACATGTTCACGACTGGTCTCGGCCCGATTGCAAATGCGATTTTTGCGGTTGCAACAATGGCTATC
GCGATTCCGACCGGGATTAAGATTTTTAACTGGCTGTTGACGATTTGGGGAGGAAATGTGAAGTATACAACCGCTATGCT
GTATGCTGTCTCATTTATTCCATCCTTTGTGCTCGGCGGTGTGACGGGAGTCATGCTGGCAGCTGCTGCGGCTGATTATC
AGTTTCATGATACGTATTTTGTGGTTGCGCACTTCCACTACGTCATTATTGGCGGCGTTGTATTCGGCCTTTTAGCCGGT
GTTCATTTCTGGTGGCCGAAAATGTTCGGTAAAATTCTGCATGAAACGATGGGGAAAATTTCATTTGTATTGTTTTTTAT
CGGCTTTCACCTCACGTTTTTCATTCAGCATTTTGTCGGCTTAATGGGGATGCCGCGCCGGGTTTATACGTTTTTGCCAG
GACAGGGTCTGGAAACCGGCAACTTGATCAGTACAATCGGGGCGTTTTTTATGGCGGCAGCTGTTATTCTTCTGCTGGTC
AATGTCATATGGACATCGGTAAAAGGTGAATATGTAGGTGCTGATCCATGGCATGACGGACGTACGCTGGAATGGACCGT
TTCTTCACCGCCGCCGGAGTATAACTTTAAACAGCTTCCTTTTGTCAGAGGACTTGATCCGCTTTGGATCGAGAAGCAGG
CAGGGCACAAATCAATGACGCCGGCGGAACCGGTTGATGATATTCATATGCCAAACGGCTCAATCCTGCCGCTCATCATT
TCCTTCGGCCTTTTTGTCGCAGCGTTCGGGCTGCTGTACAGAAGTGATTACGCTTGGGGCCTGCCGGTGATCTTTATCGG
GCTCGGCATCACATTTATTACGATGCTGCTTCGTTCAGTAATTGATGATCACGGCTATCATATTCATAAAGAGGAACTGC
CGAACGATGATAAAGGGGTGAAGGCATAA

Upstream 100 bases:

>100_bases
AGCTCTCAGACAGCGAAACAAATGCGCTTTATGAATACTTAAAAGGCTTAAAAGCGGAAAGCAAGTAGGGAAGAAAGGGA
GATATTGGGGGAGGTCACAT

Downstream 100 bases:

>100_bases
TGCAAGTTCAAGAAAAATTCACCGCAGAAACCTTTCCAGCTTCTCCTGAAAAAGTAACCCTGGAAGGGAAAAATAAATTT
TTAGGCTTTTGGCTTTTTCT

Product: cytochrome caa3 oxidase subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MLNALTEKRTRGSMLWDYLTTVDHKKIAILYLVAGGFFFLVGGIEAMFIRIQLAKPENAFLSAQAYNEVMTMHGTTMIFL
AAMPLLFALMNAVVPLQIGARDVSFPFLNALGFWLFFFGGIFLNLSWFLGGAPDAGWTSYASLSLHSKGHGIDFFVLGLQ
ISGLGTLIAGINFLATIINMRAPGMTYMRLPLFTWTTFVASALILFAFPPLTVGLALMMLDRLFGTNFFNPELGGNTVIW
EHLFWIFGHPEVYILILPAFGIFSEVIPVFARKRLFGYSSMVFAIVLIGFLGFMVWVHHMFTTGLGPIANAIFAVATMAI
AIPTGIKIFNWLLTIWGGNVKYTTAMLYAVSFIPSFVLGGVTGVMLAAAAADYQFHDTYFVVAHFHYVIIGGVVFGLLAG
VHFWWPKMFGKILHETMGKISFVLFFIGFHLTFFIQHFVGLMGMPRRVYTFLPGQGLETGNLISTIGAFFMAAAVILLLV
NVIWTSVKGEYVGADPWHDGRTLEWTVSSPPPEYNFKQLPFVRGLDPLWIEKQAGHKSMTPAEPVDDIHMPNGSILPLII
SFGLFVAAFGLLYRSDYAWGLPVIFIGLGITFITMLLRSVIDDHGYHIHKEELPNDDKGVKA

Sequences:

>Translated_622_residues
MLNALTEKRTRGSMLWDYLTTVDHKKIAILYLVAGGFFFLVGGIEAMFIRIQLAKPENAFLSAQAYNEVMTMHGTTMIFL
AAMPLLFALMNAVVPLQIGARDVSFPFLNALGFWLFFFGGIFLNLSWFLGGAPDAGWTSYASLSLHSKGHGIDFFVLGLQ
ISGLGTLIAGINFLATIINMRAPGMTYMRLPLFTWTTFVASALILFAFPPLTVGLALMMLDRLFGTNFFNPELGGNTVIW
EHLFWIFGHPEVYILILPAFGIFSEVIPVFARKRLFGYSSMVFAIVLIGFLGFMVWVHHMFTTGLGPIANAIFAVATMAI
AIPTGIKIFNWLLTIWGGNVKYTTAMLYAVSFIPSFVLGGVTGVMLAAAAADYQFHDTYFVVAHFHYVIIGGVVFGLLAG
VHFWWPKMFGKILHETMGKISFVLFFIGFHLTFFIQHFVGLMGMPRRVYTFLPGQGLETGNLISTIGAFFMAAAVILLLV
NVIWTSVKGEYVGADPWHDGRTLEWTVSSPPPEYNFKQLPFVRGLDPLWIEKQAGHKSMTPAEPVDDIHMPNGSILPLII
SFGLFVAAFGLLYRSDYAWGLPVIFIGLGITFITMLLRSVIDDHGYHIHKEELPNDDKGVKA
>Mature_622_residues
MLNALTEKRTRGSMLWDYLTTVDHKKIAILYLVAGGFFFLVGGIEAMFIRIQLAKPENAFLSAQAYNEVMTMHGTTMIFL
AAMPLLFALMNAVVPLQIGARDVSFPFLNALGFWLFFFGGIFLNLSWFLGGAPDAGWTSYASLSLHSKGHGIDFFVLGLQ
ISGLGTLIAGINFLATIINMRAPGMTYMRLPLFTWTTFVASALILFAFPPLTVGLALMMLDRLFGTNFFNPELGGNTVIW
EHLFWIFGHPEVYILILPAFGIFSEVIPVFARKRLFGYSSMVFAIVLIGFLGFMVWVHHMFTTGLGPIANAIFAVATMAI
AIPTGIKIFNWLLTIWGGNVKYTTAMLYAVSFIPSFVLGGVTGVMLAAAAADYQFHDTYFVVAHFHYVIIGGVVFGLLAG
VHFWWPKMFGKILHETMGKISFVLFFIGFHLTFFIQHFVGLMGMPRRVYTFLPGQGLETGNLISTIGAFFMAAAVILLLV
NVIWTSVKGEYVGADPWHDGRTLEWTVSSPPPEYNFKQLPFVRGLDPLWIEKQAGHKSMTPAEPVDDIHMPNGSILPLII
SFGLFVAAFGLLYRSDYAWGLPVIFIGLGITFITMLLRSVIDDHGYHIHKEELPNDDKGVKA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=40.7843137254902, Blast_Score=371, Evalue=1e-102,
Organism=Escherichia coli, GI1786634, Length=627, Percent_Identity=44.0191387559809, Blast_Score=495, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=39.5480225988701, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6226524, Length=327, Percent_Identity=41.8960244648318, Blast_Score=249, Evalue=8e-67,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=34.5381526104418, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COX1_BACSU (P24010)

Other databases:

- EMBL:   X54140
- EMBL:   Z98682
- EMBL:   AL009126
- PIR:   E69609
- RefSeq:   NP_389373.2
- ProteinModelPortal:   P24010
- SMR:   P24010
- EnsemblBacteria:   EBBACT00000001088
- GeneID:   936898
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14900
- NMPDR:   fig|224308.1.peg.1492
- GenoList:   BSU14900
- GeneTree:   EBGT00050000001435
- HOGENOM:   HBG603668
- ProtClustDB:   CLSK873366
- BioCyc:   BSUB:BSU14900-MONOMER
- BRENDA:   1.9.3.1
- InterPro:   IPR000883
- InterPro:   IPR014241
- Gene3D:   G3DSA:1.20.210.10
- PANTHER:   PTHR10422
- PRINTS:   PR01165
- TIGRFAMs:   TIGR02891

Pfam domain/function: PF00115 COX1; SSF81442 COX1

EC number: =1.9.3.1

Molecular weight: Translated: 69029; Mature: 69029

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50855 COX1; PS00077 COX1_CUB; PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe7d56fc)-; HASH(0xecd70bc)-; HASH(0xecc14e4)-; HASH(0xe78d9b4)-; HASH(0xe548bfc)-; HASH(0xec86020)-; HASH(0xd876aa4)-; HASH(0xdabf778)-; HASH(0xedfacb4)-; HASH(0xeb4d6bc)-; HASH(0xebe345c)-; HASH(0xf14f7ac)-; HASH(0xe6673c4)-; HASH(0xe7c1d04)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNALTEKRTRGSMLWDYLTTVDHKKIAILYLVAGGFFFLVGGIEAMFIRIQLAKPENAF
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHEEEEEEEEEECCCCHH
LSAQAYNEVMTMHGTTMIFLAAMPLLFALMNAVVPLQIGARDVSFPFLNALGFWLFFFGG
EEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEHEECCCCCCHHHHHHHHHHHHHHHH
IFLNLSWFLGGAPDAGWTSYASLSLHSKGHGIDFFVLGLQISGLGTLIAGINFLATIINM
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHH
RAPGMTYMRLPLFTWTTFVASALILFAFPPLTVGLALMMLDRLFGTNFFNPELGGNTVIW
CCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHH
EHLFWIFGHPEVYILILPAFGIFSEVIPVFARKRLFGYSSMVFAIVLIGFLGFMVWVHHM
HHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
FTTGLGPIANAIFAVATMAIAIPTGIKIFNWLLTIWGGNVKYTTAMLYAVSFIPSFVLGG
HHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
VTGVMLAAAAADYQFHDTYFVVAHFHYVIIGGVVFGLLAGVHFWWPKMFGKILHETMGKI
HHHHHHHHHHCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFVLFFIGFHLTFFIQHFVGLMGMPRRVYTFLPGQGLETGNLISTIGAFFMAAAVILLLV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NVIWTSVKGEYVGADPWHDGRTLEWTVSSPPPEYNFKQLPFVRGLDPLWIEKQAGHKSMT
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCEEECCCCCCCCC
PAEPVDDIHMPNGSILPLIISFGLFVAAFGLLYRSDYAWGLPVIFIGLGITFITMLLRSV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IDDHGYHIHKEELPNDDKGVKA
HHCCCCEEEHHHCCCCCCCCCH
>Mature Secondary Structure
MLNALTEKRTRGSMLWDYLTTVDHKKIAILYLVAGGFFFLVGGIEAMFIRIQLAKPENAF
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHEEEEEEEEEECCCCHH
LSAQAYNEVMTMHGTTMIFLAAMPLLFALMNAVVPLQIGARDVSFPFLNALGFWLFFFGG
EEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEHEECCCCCCHHHHHHHHHHHHHHHH
IFLNLSWFLGGAPDAGWTSYASLSLHSKGHGIDFFVLGLQISGLGTLIAGINFLATIINM
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHH
RAPGMTYMRLPLFTWTTFVASALILFAFPPLTVGLALMMLDRLFGTNFFNPELGGNTVIW
CCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHH
EHLFWIFGHPEVYILILPAFGIFSEVIPVFARKRLFGYSSMVFAIVLIGFLGFMVWVHHM
HHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
FTTGLGPIANAIFAVATMAIAIPTGIKIFNWLLTIWGGNVKYTTAMLYAVSFIPSFVLGG
HHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
VTGVMLAAAAADYQFHDTYFVVAHFHYVIIGGVVFGLLAGVHFWWPKMFGKILHETMGKI
HHHHHHHHHHCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFVLFFIGFHLTFFIQHFVGLMGMPRRVYTFLPGQGLETGNLISTIGAFFMAAAVILLLV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NVIWTSVKGEYVGADPWHDGRTLEWTVSSPPPEYNFKQLPFVRGLDPLWIEKQAGHKSMT
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCEEECCCCCCCCC
PAEPVDDIHMPNGSILPLIISFGLFVAAFGLLYRSDYAWGLPVIFIGLGITFITMLLRSV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
IDDHGYHIHKEELPNDDKGVKA
HHCCCCEEEHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377