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The map label for this gene is tlpC

Identifier: 255767103

GI number: 255767103

Start: 372771

End: 374492

Strand: Reverse

Name: tlpC

Synonym: BSU03440

Alternate gene names: 255767103

Gene position: 374492-372771 (Counterclockwise)

Preceding gene: 16077414

Following gene: 50812179

Centisome position: 8.88

GC content: 42.33

Gene sequence:

>1722_bases
ATGTTGATAAAACGATTTAAGATGAAGCTAGGAACTAAAATTCTTTGCCTCGTTTTCGTGGTGATTCTTTTGTTTTCGGC
ATCAGTTGGCACTGTGATGCTTAAGGAAATTACAGAAAGCATGAAACAAATGGCAACTGAAAAAGCGAAAGGTGATCTCG
CTTTAAGCAGCACTTATATTGATGATGTCATGTCAGGCGACTGGCAGGTGAAAAACAATAAGCTCTATAAAGGGCAAACA
CAAATCAATGGAAATGAAGATATTGTTGATCTGCTTGGTGAAAAGACAGGTGATACCATTACCATTTTCCAAGGCGATAC
TCGTGTTGCAACCAATGTCATGAAAAATGGCGAAAGAGCCGTCGGCACCCAGGCTTCTTCTGAAGTTATTGCCGCTGTTT
TAAAGAAAGGAAAGCGTTTTTACGGACAAGCAGATGTAGCAGGTTCTTCTTATCAGACTGCATACATGCCGTTAAAAGAT
CAAAATGGGAACATCATCGGCATGCTGTATACCGGAGCTAATCAAAGTATTTTAGCATCACTTACACAATCACTTTTCAC
TCAATTCGCTATCGTTCTTGTTATCGTCATTATGGTATCAGTCATCCTTGTCTTGGTTTTCACCAGAAAAATCAACAAGC
GGCTGAACGCTTTAAAAAGCGCCTTTGAAAGTGCCGGAAACGGAGATATGACAATAGAGGTGTCAGACAAAACCGGTGAC
GAGCTTTCAGAACTAAGCGTCTATTATAATAAGATGAGAATGAAGCTGAACGATACCATACAAACCGTACAACAATCAGC
CCTTCAGCTTGCGTCAGCCTCTCAGCAGCTCTCAGCCGGAGCAGAGGAAACAAATCAAGCTTCAGAAAAAATCACAGAAG
CTGTACAGCAGATTGCAAATGGAGCCCAAGATCAGATCACCCGAATTGAAAATAGTGAAAGCTCATTAAAACAAGCTTCA
GCAGACATCCGGGATATTTCTGCAAATACTGCCGCTATCGCTGACAAAGGGCAGCTCGCTCAATCAAAAGCAGACATTGG
ACAAAAGGAAATTGCAAATGTACAGGCGCAAATGGATGCGATTCACCAGTCAATTCAGAAAAGCGGAGAAATCATACACC
AGTTAGACGGCCGCTCTAAACAAATTGAGCAAATTTTATCGGTCATCACCCAAATTGCTGATCAGACAAACCTGCTTGCG
CTGAATGCAGCGATTGAAGCTGCCAGAGCCGGTGAACAAGGAAAAGGCTTTGCTGTTGTTGCTGATGAAGTACGGAAATT
AGCAGAAGAGTCTCAACAGTCTGCGGGGCAGATTTCAAAACTGATCATAGAAATACAAAAGGATATGAACCGGTCTGCAA
GATCTGTTGAGCATGTGAAAACAGAAGCTGCAGAAGGAGTCACCATGATCCAGCGCACCAGAGATGCATTTAAGGAAATT
GCAGCTGCAACAGGTGAAATCAGCGCCGAGATTAGTGATTTATCAGCATCTGTAACAAACATTTCAGCCAGTGCACATCA
AATAAATGATTCCTTTGCAGCCAATACGGCCGACATTAAAGAATCTACTAAAAATACCCGGCAAGCGGCTGCATTAACAG
AGGAGCAATTTGCTGCAATGGAGGAGATTACCGCAGCTTCTGAAACACTTTCTCAATTAGCTGAGGAGCTTACCGGTATC
ATAAGCCAATTTAAAATGATTAATCAAGCCGAAAACGGCTGA

Upstream 100 bases:

>100_bases
CCGGCCTGAAGATCAGGCCGGTTTTATTTTTTCTAAAATAAAACTTTAAACCCAAAAACCCGATAAGTAATATGACCTGC
AAATCGTAAAGGGAGGAATT

Downstream 100 bases:

>100_bases
TGACTTACTATCATTATTGTAAATTGGCAATCGTATTTTGCTGAAAACAAATATTTCGATCTGCTAAAATTACGATTTCT
GCAATAAACTGATCGTAAAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQMATEKAKGDLALSSTYIDDVMSGDWQVKNNKLYKGQT
QINGNEDIVDLLGEKTGDTITIFQGDTRVATNVMKNGERAVGTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKD
QNGNIIGMLYTGANQSILASLTQSLFTQFAIVLVIVIMVSVILVLVFTRKINKRLNALKSAFESAGNGDMTIEVSDKTGD
ELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGAEETNQASEKITEAVQQIANGAQDQITRIENSESSLKQAS
ADIRDISANTAAIADKGQLAQSKADIGQKEIANVQAQMDAIHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLLA
LNAAIEAARAGEQGKGFAVVADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEHVKTEAAEGVTMIQRTRDAFKEI
AAATGEISAEISDLSASVTNISASAHQINDSFAANTADIKESTKNTRQAAALTEEQFAAMEEITAASETLSQLAEELTGI
ISQFKMINQAENG

Sequences:

>Translated_573_residues
MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQMATEKAKGDLALSSTYIDDVMSGDWQVKNNKLYKGQT
QINGNEDIVDLLGEKTGDTITIFQGDTRVATNVMKNGERAVGTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKD
QNGNIIGMLYTGANQSILASLTQSLFTQFAIVLVIVIMVSVILVLVFTRKINKRLNALKSAFESAGNGDMTIEVSDKTGD
ELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGAEETNQASEKITEAVQQIANGAQDQITRIENSESSLKQAS
ADIRDISANTAAIADKGQLAQSKADIGQKEIANVQAQMDAIHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLLA
LNAAIEAARAGEQGKGFAVVADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEHVKTEAAEGVTMIQRTRDAFKEI
AAATGEISAEISDLSASVTNISASAHQINDSFAANTADIKESTKNTRQAAALTEEQFAAMEEITAASETLSQLAEELTGI
ISQFKMINQAENG
>Mature_573_residues
MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQMATEKAKGDLALSSTYIDDVMSGDWQVKNNKLYKGQT
QINGNEDIVDLLGEKTGDTITIFQGDTRVATNVMKNGERAVGTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKD
QNGNIIGMLYTGANQSILASLTQSLFTQFAIVLVIVIMVSVILVLVFTRKINKRLNALKSAFESAGNGDMTIEVSDKTGD
ELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGAEETNQASEKITEAVQQIANGAQDQITRIENSESSLKQAS
ADIRDISANTAAIADKGQLAQSKADIGQKEIANVQAQMDAIHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLLA
LNAAIEAARAGEQGKGFAVVADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEHVKTEAAEGVTMIQRTRDAFKEI
AAATGEISAEISDLSASVTNISASAHQINDSFAANTADIKESTKNTRQAAALTEEQFAAMEEITAASETLSQLAEELTGI
ISQFKMINQAENG

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain

Homologues:

Organism=Escherichia coli, GI1787690, Length=374, Percent_Identity=29.9465240641711, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI2367378, Length=350, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788194, Length=308, Percent_Identity=31.1688311688312, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788195, Length=282, Percent_Identity=32.2695035460993, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1789453, Length=343, Percent_Identity=30.6122448979592, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TLPC_BACSU (P39209)

Other databases:

- EMBL:   Z34005
- EMBL:   D30762
- EMBL:   D50453
- EMBL:   AL009126
- PIR:   I40496
- RefSeq:   NP_388226.2
- ProteinModelPortal:   P39209
- SMR:   P39209
- EnsemblBacteria:   EBBACT00000000480
- GeneID:   938316
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU03440
- NMPDR:   fig|224308.1.peg.345
- GenoList:   BSU03440
- GeneTree:   EBGT00070000032300
- HOGENOM:   HBG616052
- ProtClustDB:   CLSK886673
- BioCyc:   BSUB:BSU03440-MONOMER
- GO:   GO:0006935
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- PRINTS:   PR00260
- SMART:   SM00304
- SMART:   SM00283

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal

EC number: NA

Molecular weight: Translated: 61785; Mature: 61785

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00538 CHEMOTAXIS_TRANSDUC_1; PS50111 CHEMOTAXIS_TRANSDUC_2; PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc4e9060)-; HASH(0xcc19548)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQMATEKAKGDLALSSTYI
CCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
DDVMSGDWQVKNNKLYKGQTQINGNEDIVDLLGEKTGDTITIFQGDTRVATNVMKNGERA
HHHHCCCEEECCCEEECCCCCCCCCHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCHH
VGTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKDQNGNIIGMLYTGANQSILAS
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCHHHHHH
LTQSLFTQFAIVLVIVIMVSVILVLVFTRKINKRLNALKSAFESAGNGDMTIEVSDKTGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
ELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGAEETNQASEKITEAVQQIAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
GAQDQITRIENSESSLKQASADIRDISANTAAIADKGQLAQSKADIGQKEIANVQAQMDA
CHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHH
IHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLLALNAAIEAARAGEQGKGFAVV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEH
ADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEHVKTEAAEGVTMIQRTRDAFKEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAATGEISAEISDLSASVTNISASAHQINDSFAANTADIKESTKNTRQAAALTEEQFAAM
HHHCCHHHHHHHHHHHHHHHCCHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EEITAASETLSQLAEELTGIISQFKMINQAENG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MLIKRFKMKLGTKILCLVFVVILLFSASVGTVMLKEITESMKQMATEKAKGDLALSSTYI
CCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
DDVMSGDWQVKNNKLYKGQTQINGNEDIVDLLGEKTGDTITIFQGDTRVATNVMKNGERA
HHHHCCCEEECCCEEECCCCCCCCCHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCCHH
VGTQASSEVIAAVLKKGKRFYGQADVAGSSYQTAYMPLKDQNGNIIGMLYTGANQSILAS
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCHHHHHH
LTQSLFTQFAIVLVIVIMVSVILVLVFTRKINKRLNALKSAFESAGNGDMTIEVSDKTGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
ELSELSVYYNKMRMKLNDTIQTVQQSALQLASASQQLSAGAEETNQASEKITEAVQQIAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
GAQDQITRIENSESSLKQASADIRDISANTAAIADKGQLAQSKADIGQKEIANVQAQMDA
CHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCHHHHHHHHHHHHH
IHQSIQKSGEIIHQLDGRSKQIEQILSVITQIADQTNLLALNAAIEAARAGEQGKGFAVV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEH
ADEVRKLAEESQQSAGQISKLIIEIQKDMNRSARSVEHVKTEAAEGVTMIQRTRDAFKEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAATGEISAEISDLSASVTNISASAHQINDSFAANTADIKESTKNTRQAAALTEEQFAAM
HHHCCHHHHHHHHHHHHHHHCCHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EEITAASETLSQLAEELTGIISQFKMINQAENG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377