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The map label for this gene is yybO

Identifier: 16081109

GI number: 16081109

Start: 4170045

End: 4171352

Strand: Direct

Name: yybO

Synonym: BSU40570

Alternate gene names: 16081109

Gene position: 4170045-4171352 (Clockwise)

Preceding gene: 16081107

Following gene: 16081110

Centisome position: 98.92

GC content: 46.25

Gene sequence:

>1308_bases
ATGACAGAGGAGGTTTTCATCATGAGTCAAGAGCGCGTGAAACGGCCTGGGCATACCAGATGGTACATATCTTCGTTACT
TAGCGGCATTATTATTCTTAATTATTTTGACCGAGTGGCCATCTCGGTAGCGGCCCCTGCGATACAAGATTCGTTTCACC
TTACTGCAACTGAACTCGGCATCGTGTTTTCCATTTACACCTATTCCTATACACTGATGCAGCTGCCTGTCGGAAGTTTG
CTGGACCGTTTTGGGGTCGCATGGGTCACGAGGGTTGGAATGACAATATGGAGCTTTTTAACGATCCTTCTTGCTTTTTT
GCAAGGAAAATTGCTGTTGTATCTGTTCCGGTTTCTCATTGGGCTGACGAGCGCCTCTGCGTTCCCTGCTGCCTCTAAAG
CAACCGCTCTCTGGTTTCCTCCAAGTGAGCGGGGATTGGCAAACTCACTGTTCGATTCGGCCGCCAAGTTTTCAAATGTA
ATCGGCGCGCCATTGGTCGCCTTTCTTGTCACAACATTTGACTGGCGTGTCGCTTTTTTGACGATTGGATGCATCAATGT
GCTGTTTACGATCTTTTTCTGGCAGTATTATGAACAGCCTGAACGGCACAAACGCATTTCTAAAAGTGAACTAAACTATA
TTCAAAAACACAATGCCATTACAACAGAGCAAATCCCTTACAAAACGGGCCCGCTTTTAAAAAAGCTTTTCACCAATCGA
AAAGTATGGGGCTTAATGATCGGATTTACAGGGTACGGGTATACATTCAACCTGCTGCTCACCTGGCTTCCGACTTTCTT
TAAACATACATACGGTATGGATCTCATGTCGTCCGGTTTATTTACGGCAGTGCCGTGGCTGATCTCAACCATTTCCGGAA
TTGCCGTCGGCGGCTGGCTCGTCGATTATTTTATTAAGAAAGGCTATCCTAATACCAAGGTGTACCGAACCGTAATCATA
GTCGGAATGAGCTTTGGCTTTTTCTTTTTAGGATCCATTCTGACGAACAATATTACCGTAGCCATTATTTGCATTTCCAT
CGGACTCGCCGGAATTTCCGCAACCGCTCCGGTCGGCTGGTCCATCTCCGCAGAACTCGCGCCGATCGGTTCCGTATCCA
TGCTGAGCTCCATGGTGAATCTCGCAAACAACCTGTTCGGAGGCATTATTGCTGCGTCACTGACAGGGTATTTGTTTGAT
GTGACAGGCTCCTTTACCCTCAGCTTTCTGGTAGCTGGTTTTGTGCTGTTGCTGGGATTGGTTTTTTATGTGTTTGTATT
AGGGGATGTAAAACGAATTAAACTATAG

Upstream 100 bases:

>100_bases
TCTAAAGCACCGATCTGTTCCAGTCAAATTCCTGCCGTTTATATAAAAGCGCGCTGTGGTATTTAAAATTTGAATGGTTT
TTCTATCAGGAGATCATGCT

Downstream 100 bases:

>100_bases
AACATGAAAAAGAGAGCTGCCAGTTGGCAGCTCTCCCTTTACATCAAAGAATCGGCCCGTCCCCATTTACCTTCTCCTCG
TCCTGTTCCTCTATATCAAG

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MTEEVFIMSQERVKRPGHTRWYISSLLSGIIILNYFDRVAISVAAPAIQDSFHLTATELGIVFSIYTYSYTLMQLPVGSL
LDRFGVAWVTRVGMTIWSFLTILLAFLQGKLLLYLFRFLIGLTSASAFPAASKATALWFPPSERGLANSLFDSAAKFSNV
IGAPLVAFLVTTFDWRVAFLTIGCINVLFTIFFWQYYEQPERHKRISKSELNYIQKHNAITTEQIPYKTGPLLKKLFTNR
KVWGLMIGFTGYGYTFNLLLTWLPTFFKHTYGMDLMSSGLFTAVPWLISTISGIAVGGWLVDYFIKKGYPNTKVYRTVII
VGMSFGFFFLGSILTNNITVAIICISIGLAGISATAPVGWSISAELAPIGSVSMLSSMVNLANNLFGGIIAASLTGYLFD
VTGSFTLSFLVAGFVLLLGLVFYVFVLGDVKRIKL

Sequences:

>Translated_435_residues
MTEEVFIMSQERVKRPGHTRWYISSLLSGIIILNYFDRVAISVAAPAIQDSFHLTATELGIVFSIYTYSYTLMQLPVGSL
LDRFGVAWVTRVGMTIWSFLTILLAFLQGKLLLYLFRFLIGLTSASAFPAASKATALWFPPSERGLANSLFDSAAKFSNV
IGAPLVAFLVTTFDWRVAFLTIGCINVLFTIFFWQYYEQPERHKRISKSELNYIQKHNAITTEQIPYKTGPLLKKLFTNR
KVWGLMIGFTGYGYTFNLLLTWLPTFFKHTYGMDLMSSGLFTAVPWLISTISGIAVGGWLVDYFIKKGYPNTKVYRTVII
VGMSFGFFFLGSILTNNITVAIICISIGLAGISATAPVGWSISAELAPIGSVSMLSSMVNLANNLFGGIIAASLTGYLFD
VTGSFTLSFLVAGFVLLLGLVFYVFVLGDVKRIKL
>Mature_434_residues
TEEVFIMSQERVKRPGHTRWYISSLLSGIIILNYFDRVAISVAAPAIQDSFHLTATELGIVFSIYTYSYTLMQLPVGSLL
DRFGVAWVTRVGMTIWSFLTILLAFLQGKLLLYLFRFLIGLTSASAFPAASKATALWFPPSERGLANSLFDSAAKFSNVI
GAPLVAFLVTTFDWRVAFLTIGCINVLFTIFFWQYYEQPERHKRISKSELNYIQKHNAITTEQIPYKTGPLLKKLFTNRK
VWGLMIGFTGYGYTFNLLLTWLPTFFKHTYGMDLMSSGLFTAVPWLISTISGIAVGGWLVDYFIKKGYPNTKVYRTVIIV
GMSFGFFFLGSILTNNITVAIICISIGLAGISATAPVGWSISAELAPIGSVSMLSSMVNLANNLFGGIIAASLTGYLFDV
TGSFTLSFLVAGFVLLLGLVFYVFVLGDVKRIKL

Specific function: Uptake Of D-Galactarate. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family

Homologues:

Organism=Homo sapiens, GI154350196, Length=410, Percent_Identity=26.3414634146341, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI6912666, Length=409, Percent_Identity=26.6503667481663, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI9966811, Length=427, Percent_Identity=23.6533957845433, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI21322234, Length=426, Percent_Identity=24.4131455399061, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI9945322, Length=406, Percent_Identity=24.1379310344828, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI148743791, Length=283, Percent_Identity=24.7349823321555, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI5031955, Length=282, Percent_Identity=25.531914893617, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4885441, Length=277, Percent_Identity=24.5487364620939, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI148728191, Length=311, Percent_Identity=23.4726688102894, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789515, Length=439, Percent_Identity=29.6127562642369, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789152, Length=447, Percent_Identity=28.8590604026846, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=28.9411764705882, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI2367379, Length=405, Percent_Identity=29.6296296296296, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI2367193, Length=424, Percent_Identity=26.4150943396226, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082071, Length=395, Percent_Identity=25.0632911392405, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997452, Length=392, Percent_Identity=27.8061224489796, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI115533556, Length=330, Percent_Identity=26.0606060606061, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115533554, Length=330, Percent_Identity=26.0606060606061, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17552542, Length=404, Percent_Identity=28.2178217821782, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554148, Length=367, Percent_Identity=26.7029972752044, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17554962, Length=314, Percent_Identity=25.796178343949, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17560030, Length=334, Percent_Identity=24.251497005988, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193208223, Length=300, Percent_Identity=25.3333333333333, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561498, Length=187, Percent_Identity=28.3422459893048, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534558, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17535049, Length=286, Percent_Identity=20.2797202797203, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=270, Percent_Identity=23.7037037037037, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17532009, Length=288, Percent_Identity=20.8333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569727, Length=414, Percent_Identity=22.9468599033816, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=297, Percent_Identity=24.9158249158249, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563054, Length=302, Percent_Identity=23.841059602649, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=321, Percent_Identity=23.6760124610592, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71991448, Length=321, Percent_Identity=23.6760124610592, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560966, Length=292, Percent_Identity=23.6301369863014, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25145142, Length=298, Percent_Identity=23.8255033557047, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533871, Length=318, Percent_Identity=22.9559748427673, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536545, Length=255, Percent_Identity=24.7058823529412, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32565916, Length=246, Percent_Identity=21.9512195121951, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540458, Length=233, Percent_Identity=23.175965665236, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=246, Percent_Identity=21.9512195121951, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17557432, Length=263, Percent_Identity=23.574144486692, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115534564, Length=263, Percent_Identity=23.574144486692, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI62484226, Length=388, Percent_Identity=26.8041237113402, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641682, Length=317, Percent_Identity=27.4447949526814, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24654215, Length=401, Percent_Identity=26.1845386533666, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24648416, Length=396, Percent_Identity=26.010101010101, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356189, Length=396, Percent_Identity=26.010101010101, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19922400, Length=401, Percent_Identity=26.1845386533666, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583789, Length=315, Percent_Identity=25.7142857142857, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24584153, Length=402, Percent_Identity=23.8805970149254, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28573708, Length=393, Percent_Identity=24.6819338422392, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573707, Length=393, Percent_Identity=24.6819338422392, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573299, Length=444, Percent_Identity=24.0990990990991, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639764, Length=461, Percent_Identity=24.5119305856833, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20130167, Length=406, Percent_Identity=24.1379310344828, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920686, Length=446, Percent_Identity=22.4215246636771, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45550460, Length=315, Percent_Identity=25.7142857142857, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24655255, Length=304, Percent_Identity=25.3289473684211, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129235, Length=307, Percent_Identity=25.4071661237785, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653727, Length=363, Percent_Identity=24.2424242424242, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24658658, Length=431, Percent_Identity=24.3619489559165, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24580790, Length=285, Percent_Identity=24.2105263157895, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130135, Length=276, Percent_Identity=24.2753623188406, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24655271, Length=276, Percent_Identity=24.2753623188406, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281361682, Length=229, Percent_Identity=24.8908296943231, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YYBO_BACSU (P37489)

Other databases:

- EMBL:   D26185
- EMBL:   AL009126
- PIR:   S65982
- RefSeq:   NP_391937.1
- ProteinModelPortal:   P37489
- EnsemblBacteria:   EBBACT00000002403
- GeneID:   937836
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU40570
- NMPDR:   fig|224308.1.peg.4063
- GenoList:   BSU40570
- GeneTree:   EBGT00050000000112
- HOGENOM:   HBG338043
- OMA:   RHKRISK
- PhylomeDB:   P37489
- ProtClustDB:   CLSK626763
- BioCyc:   BSUB:BSU40570-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 48248; Mature: 48117

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13907b6c)-; HASH(0x13933ee0)-; HASH(0x119371e0)-; HASH(0x1171834c)-; HASH(0x12f89724)-; HASH(0x139104e8)-; HASH(0x138d4fec)-; HASH(0x138d2564)-; HASH(0xb3561bc)-; HASH(0x1393d504)-; HASH(0x139cbf14)-; HASH(0x13607d94)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEVFIMSQERVKRPGHTRWYISSLLSGIIILNYFDRVAISVAAPAIQDSFHLTATELG
CCCCEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
IVFSIYTYSYTLMQLPVGSLLDRFGVAWVTRVGMTIWSFLTILLAFLQGKLLLYLFRFLI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLTSASAFPAASKATALWFPPSERGLANSLFDSAAKFSNVIGAPLVAFLVTTFDWRVAFL
HHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIGCINVLFTIFFWQYYEQPERHKRISKSELNYIQKHNAITTEQIPYKTGPLLKKLFTNR
HHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCC
KVWGLMIGFTGYGYTFNLLLTWLPTFFKHTYGMDLMSSGLFTAVPWLISTISGIAVGGWL
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VDYFIKKGYPNTKVYRTVIIVGMSFGFFFLGSILTNNITVAIICISIGLAGISATAPVGW
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCCCCCC
SISAELAPIGSVSMLSSMVNLANNLFGGIIAASLTGYLFDVTGSFTLSFLVAGFVLLLGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHH
VFYVFVLGDVKRIKL
HHHHHHHCCHHHCCH
>Mature Secondary Structure 
TEEVFIMSQERVKRPGHTRWYISSLLSGIIILNYFDRVAISVAAPAIQDSFHLTATELG
CCCEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
IVFSIYTYSYTLMQLPVGSLLDRFGVAWVTRVGMTIWSFLTILLAFLQGKLLLYLFRFLI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLTSASAFPAASKATALWFPPSERGLANSLFDSAAKFSNVIGAPLVAFLVTTFDWRVAFL
HHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIGCINVLFTIFFWQYYEQPERHKRISKSELNYIQKHNAITTEQIPYKTGPLLKKLFTNR
HHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCC
KVWGLMIGFTGYGYTFNLLLTWLPTFFKHTYGMDLMSSGLFTAVPWLISTISGIAVGGWL
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VDYFIKKGYPNTKVYRTVIIVGMSFGFFFLGSILTNNITVAIICISIGLAGISATAPVGW
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHCCCCCCCCCC
SISAELAPIGSVSMLSSMVNLANNLFGGIIAASLTGYLFDVTGSFTLSFLVAGFVLLLGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHH
VFYVFVLGDVKRIKL
HHHHHHHCCHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377