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The map label for this gene is yycR

Identifier: 16081077

GI number: 16081077

Start: 4135798

End: 4137024

Strand: Reverse

Name: yycR

Synonym: BSU40250

Alternate gene names: 16081077

Gene position: 4137024-4135798 (Counterclockwise)

Preceding gene: 255767869

Following gene: 255767868

Centisome position: 98.14

GC content: 53.46

Gene sequence:

>1227_bases
ATGGGAGGAATGGCGTTGACAGGAAACAAAGCGGTTGTGTACAAAGGCAAAGGGACTGTAGCGGTGGAGGATATCGGTTA
TCCGGAGTTAATCTTGAGGGACGGGCCCGGCGTCCCGAAGGCGAATGTGAATCGAAAATGTGAGCATGGGGTTATTCTCA
AAGTCATTACAACCAACATTTGCGGAAGCGACCAGCATATGGTCAGAGGCCGCACAACGGCGCCAGAAGGCTTGGTGCTC
GGGCATGAAATTACGGGAGAAGTCATTGAAACGGGGCGTGATGTTGAATTTATCAAAAAAGGAGATATCGTATCCGTTCC
TTTCAATATTGCCTGCGGACGCTGTGTGATGTGCAAAACGCAGAAAACGCATGTGTGCCTGAATGTCAATCCGGACCGGC
CGGGATCGGCTTACGGCTACGTCGATATGGGCGGCTGGGTCGGCGGCCAGTCTGAATATGTCATGGTGCCATACGCTGAT
TTTCAGCTTTTGGTATTCCCTGATAAAGAACAGGCGCTAGAAAAGATTCTCGATTTGACCATGCTGTCCGACATTTTTCC
GACCGGCTTCCATGGAGCTTATACAGCGGGCGTGCAAACAGGTTCAACCGTTTATATCGCTGGAGCGGGTCCTGTCGGCT
TGGCAGCTGCACACTCCGCTCAGCTCCTAGGCGCCTCTACCGTGATTGTCGGCGATCTGAACGAAGACAGGCTGGCACAG
GCCAGAAGCTTCGGCTGTGAAACGGTCAACGTGCAAAAACACGACCGCCTCGGCGAGCAAATTGAACAAATACTAGGTGA
ACCAACCGTTGATGCTGCAGTGGACTGTGTCGGCTTTGAAGCATCTGGGCACGGCAATCAAGGAGAAGCGCCAGCCGCCG
TGCTGAACTCAATCATGGACGTCACCCAGGTCGGAGGCAGCCTTGGCATTCCAGGCTTATACGTGACCGAAGATCCCGGT
GCAAAGGATGCGGACGCCAAAACAGGCTCATTAAAAATCCGCTTCGGACTCGGCTGGGCCAAAGCCCACACCTTCGTCAC
CGGACAAACGCCCGCCATGACATACAACCGCAATTTGATGAAAGCGATCCTGAGCGGCAGAGCGCAGATCGCAAAAGCCG
TCAATGCCACCGTTATTTCTCTGGACGACGCGCCAAAAGGCTACAGCGACTTCGACAAAGGCGCAGCCAAAAAATTCGTC
ATCGACCCGCATGGGACATTGAAGTAA

Upstream 100 bases:

>100_bases
TATTTGTTGTTGTAAGAATACAGAAAAAACAGTCGTGAAAAAGGGAAAGAGTCATGCCGAACCGAAGTCATGTTCAAGGA
CGGAGAGTCCAAACACATGA

Downstream 100 bases:

>100_bases
AAGAAAAAGCCGGACGTTCTCAGAACGCCGGCTTTATTGCTGGTAATCCGTTTCTTCAAAGCGATCTCCTGTTTCGTCTT
GAACAATTAAATCCCCTTCA

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MGGMALTGNKAVVYKGKGTVAVEDIGYPELILRDGPGVPKANVNRKCEHGVILKVITTNICGSDQHMVRGRTTAPEGLVL
GHEITGEVIETGRDVEFIKKGDIVSVPFNIACGRCVMCKTQKTHVCLNVNPDRPGSAYGYVDMGGWVGGQSEYVMVPYAD
FQLLVFPDKEQALEKILDLTMLSDIFPTGFHGAYTAGVQTGSTVYIAGAGPVGLAAAHSAQLLGASTVIVGDLNEDRLAQ
ARSFGCETVNVQKHDRLGEQIEQILGEPTVDAAVDCVGFEASGHGNQGEAPAAVLNSIMDVTQVGGSLGIPGLYVTEDPG
AKDADAKTGSLKIRFGLGWAKAHTFVTGQTPAMTYNRNLMKAILSGRAQIAKAVNATVISLDDAPKGYSDFDKGAAKKFV
IDPHGTLK

Sequences:

>Translated_408_residues
MGGMALTGNKAVVYKGKGTVAVEDIGYPELILRDGPGVPKANVNRKCEHGVILKVITTNICGSDQHMVRGRTTAPEGLVL
GHEITGEVIETGRDVEFIKKGDIVSVPFNIACGRCVMCKTQKTHVCLNVNPDRPGSAYGYVDMGGWVGGQSEYVMVPYAD
FQLLVFPDKEQALEKILDLTMLSDIFPTGFHGAYTAGVQTGSTVYIAGAGPVGLAAAHSAQLLGASTVIVGDLNEDRLAQ
ARSFGCETVNVQKHDRLGEQIEQILGEPTVDAAVDCVGFEASGHGNQGEAPAAVLNSIMDVTQVGGSLGIPGLYVTEDPG
AKDADAKTGSLKIRFGLGWAKAHTFVTGQTPAMTYNRNLMKAILSGRAQIAKAVNATVISLDDAPKGYSDFDKGAAKKFV
IDPHGTLK
>Mature_407_residues
GGMALTGNKAVVYKGKGTVAVEDIGYPELILRDGPGVPKANVNRKCEHGVILKVITTNICGSDQHMVRGRTTAPEGLVLG
HEITGEVIETGRDVEFIKKGDIVSVPFNIACGRCVMCKTQKTHVCLNVNPDRPGSAYGYVDMGGWVGGQSEYVMVPYADF
QLLVFPDKEQALEKILDLTMLSDIFPTGFHGAYTAGVQTGSTVYIAGAGPVGLAAAHSAQLLGASTVIVGDLNEDRLAQA
RSFGCETVNVQKHDRLGEQIEQILGEPTVDAAVDCVGFEASGHGNQGEAPAAVLNSIMDVTQVGGSLGIPGLYVTEDPGA
KDADAKTGSLKIRFGLGWAKAHTFVTGQTPAMTYNRNLMKAILSGRAQIAKAVNATVISLDDAPKGYSDFDKGAAKKFVI
DPHGTLK

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family

Homologues:

Organism=Homo sapiens, GI4501933, Length=244, Percent_Identity=31.5573770491803, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4501929, Length=254, Percent_Identity=31.496062992126, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI34577061, Length=292, Percent_Identity=28.7671232876712, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI71565154, Length=286, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI71743840, Length=228, Percent_Identity=27.1929824561404, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI262073058, Length=228, Percent_Identity=27.1929824561404, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786825, Length=411, Percent_Identity=34.0632603406326, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1790045, Length=365, Percent_Identity=29.3150684931507, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790718, Length=265, Percent_Identity=26.7924528301887, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082125, Length=255, Percent_Identity=30.5882352941176, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788073, Length=280, Percent_Identity=29.6428571428571, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787863, Length=232, Percent_Identity=31.0344827586207, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI226510992, Length=348, Percent_Identity=27.0114942528736, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562878, Length=248, Percent_Identity=29.8387096774194, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17562876, Length=264, Percent_Identity=30.6818181818182, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320033, Length=289, Percent_Identity=33.2179930795848, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322619, Length=319, Percent_Identity=26.9592476489028, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319258, Length=303, Percent_Identity=25.7425742574257, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17137530, Length=244, Percent_Identity=32.3770491803279, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17737897, Length=247, Percent_Identity=31.1740890688259, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737895, Length=258, Percent_Identity=30.2325581395349, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YYCR_BACSU (Q45604)

Other databases:

- EMBL:   D78193
- EMBL:   AL009126
- PIR:   F70090
- RefSeq:   NP_391905.1
- HSSP:   P46154
- ProteinModelPortal:   Q45604
- SMR:   Q45604
- EnsemblBacteria:   EBBACT00000003855
- GeneID:   937754
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU40250
- NMPDR:   fig|224308.1.peg.4031
- GenoList:   BSU40250
- GeneTree:   EBGT00050000000383
- HOGENOM:   HBG753318
- OMA:   WDRINIA
- ProtClustDB:   CLSK869339
- BioCyc:   BSUB:BSU40250-MONOMER
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR014184
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR11695
- TIGRFAMs:   TIGR02819

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 42948; Mature: 42816

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGMALTGNKAVVYKGKGTVAVEDIGYPELILRDGPGVPKANVNRKCEHGVILKVITTNI
CCCEEEECCEEEEEECCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEECC
CGSDQHMVRGRTTAPEGLVLGHEITGEVIETGRDVEFIKKGDIVSVPFNIACGRCVMCKT
CCCCCCEEECCCCCCCCEEECCCCCHHHHHCCCCEEEEECCCEEEECCCCCCCCEEEEEC
QKTHVCLNVNPDRPGSAYGYVDMGGWVGGQSEYVMVPYADFQLLVFPDKEQALEKILDLT
CCCEEEEEECCCCCCCEEEEEECCCEECCCCCEEEEEECCEEEEEECCHHHHHHHHHHHH
MLSDIFPTGFHGAYTAGVQTGSTVYIAGAGPVGLAAAHSAQLLGASTVIVGDLNEDRLAQ
HHHHHCCCCCCCEEEECCCCCCEEEEEECCCCCHHHHCHHHHCCCEEEEEECCCHHHHHH
ARSFGCETVNVQKHDRLGEQIEQILGEPTVDAAVDCVGFEASGHGNQGEAPAAVLNSIMD
HHHCCCCEECCHHHHHHHHHHHHHHCCCCHHHHEEEEEEECCCCCCCCCCHHHHHHHHHH
VTQVGGSLGIPGLYVTEDPGAKDADAKTGSLKIRFGLGWAKAHTFVTGQTPAMTYNRNLM
HHHCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEHHEEEEECCCCCEEECHHHH
KAILSGRAQIAKAVNATVISLDDAPKGYSDFDKGAAKKFVIDPHGTLK
HHHHHCHHHHHHHCCEEEEEECCCCCCCCHHCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
GGMALTGNKAVVYKGKGTVAVEDIGYPELILRDGPGVPKANVNRKCEHGVILKVITTNI
CCEEEECCEEEEEECCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEECC
CGSDQHMVRGRTTAPEGLVLGHEITGEVIETGRDVEFIKKGDIVSVPFNIACGRCVMCKT
CCCCCCEEECCCCCCCCEEECCCCCHHHHHCCCCEEEEECCCEEEECCCCCCCCEEEEEC
QKTHVCLNVNPDRPGSAYGYVDMGGWVGGQSEYVMVPYADFQLLVFPDKEQALEKILDLT
CCCEEEEEECCCCCCCEEEEEECCCEECCCCCEEEEEECCEEEEEECCHHHHHHHHHHHH
MLSDIFPTGFHGAYTAGVQTGSTVYIAGAGPVGLAAAHSAQLLGASTVIVGDLNEDRLAQ
HHHHHCCCCCCCEEEECCCCCCEEEEEECCCCCHHHHCHHHHCCCEEEEEECCCHHHHHH
ARSFGCETVNVQKHDRLGEQIEQILGEPTVDAAVDCVGFEASGHGNQGEAPAAVLNSIMD
HHHCCCCEECCHHHHHHHHHHHHHHCCCCHHHHEEEEEEECCCCCCCCCCHHHHHHHHHH
VTQVGGSLGIPGLYVTEDPGAKDADAKTGSLKIRFGLGWAKAHTFVTGQTPAMTYNRNLM
HHHCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEHHEEEEECCCCCEEECHHHH
KAILSGRAQIAKAVNATVISLDDAPKGYSDFDKGAAKKFVIDPHGTLK
HHHHHCHHHHHHHCCEEEEEECCCCCCCCHHCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377