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The map label for this gene is gntK

Identifier: 16081058

GI number: 16081058

Start: 4114141

End: 4115682

Strand: Direct

Name: gntK

Synonym: BSU40060

Alternate gene names: 16081058

Gene position: 4114141-4115682 (Clockwise)

Preceding gene: 16081057

Following gene: 16081059

Centisome position: 97.59

GC content: 48.64

Gene sequence:

>1542_bases
ATGACTAGTTATATGTTAGGAATCGATATCGGCACGACAAGCACAAAAGCTGTGCTGTTCAGTGAAAACGGAGATGTGGT
ACAGAAAGAAAGCATCGGCTACCCGCTCTATACACCGGACATCTCAACAGCTGAACAAAATCCGGAAGAGATTTTTCAGG
CAGTCATCCATACAACAGCGAGAATTACAAAACAGCATCCCGAAAAACGGATCTCTTTCATTTCGTTCAGCAGCGCCATG
CACAGCGTCATTGCAATCGACGAAAATGACAAGCCGCTGACGCCATGCATTACATGGGCCGACAACAGAAGTGAAGGCTG
GGCGCATAAGATCAAAGAGGAATTGAACGGACATGAGGTGTACAAACGGACGGGAACACCGATTCATCCGATGGCACCGT
TAAGTAAAATTGCCTGGATCACGAATGAAAGAAAAGAAATCGCTTCCAAGGCAAAAAAATATATCGGCATCAAAGAATAC
ATTTTTAAACAGCTGTTCAATGAGTATGTCATCGATTACTCATTGGCATCAGCGACAGGCATGATGAACCTGAAGGGCTT
GGATTGGGACGAAGAGGCACTGCGCATCGCAGGCATCACGCCGGATCACTTATCCAAACTCGTGCCGACAACCGAGATCT
TTCAGCACTGCAGCCCGGAAATAGCGATCCAAATGGGAATCGATCCGGAAACGCCTTTTGTCATCGGCGCCAGCGACGGC
GTGCTGTCCAACCTCGGCGTCAACGCCATTAAAAAGGGTGAAATCGCCGTCACCATCGGTACAAGCGGTGCCATTCGGAC
GATTATTGACAAGCCGCAAACCGATGAAAAAGGGAGAATTTTTTGCTATGCCTTGACGGACAAGCATTGGGTTATTGGGG
GACCTGTGAACAATGGGGGCATCGTCCTTCGCTGGATCAGAGACGAGTTTGCCTCCTCCGAAATCGAAACAGCGACACGG
CTGGGCATTGATCCATATGACGTGCTGACGAAAATTGCCCAACGCGTCAGACCCGGTTCTGACGGTCTGCTGTTCCACCC
ATATCTCGCCGGAGAACGCGCTCCGTTGTGGAATCCGGATGTACGCGGCTCATTTTTCGGCTTGACCATGTCGCATAAGA
AAGAGCATATGATACGCGCGGCATTGGAAGGCGTCATTTACAACCTGTACACGGTGTTCTTGGCGTTAACTGAATGCATG
GATGGCCCGGTAACCCGCATCCAAGCGACAGGGGGTTTTGCAAGGTCGGAGGTTTGGCGCCAAATGATGTCGGATATCTT
CGAATCAGAGGTTGTCGTTCCGGAAAGCTACGAAAGCTCATGTCTCGGCGCCTGCATTTTAGGCCTGTATGCAACAGGAA
AAATCGATTCTTTCGACGCCGTGTCCGATATGATCGGCAGCACATACAGACATACGCCGATCGAAGACTCAGCCAAGGAA
TACAGAACATTAATGCCGATTTTCATCAATCTATCAAGATTATTAGAAAATCAATATACACAAATTGCAGATTATCAGAG
GGGCTTAATCACACACAAATAG

Upstream 100 bases:

>100_bases
ATGATTCAGTCTCTTCACCAAAACTTTGATGATGTGCAGGATAAGGTAGAAGACCTATGGCTCTCACAACAAATGCTGGC
AAAAGGAGCTGAATACAACA

Downstream 100 bases:

>100_bases
TACATGACATGAAGGGGAGGGCATTACCATGCCGTTAATCATCGTTGCACTTGGGATCTTAGCATTACTATTTCTGATTA
TGGGCTTAAAATTAAACACA

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MTSYMLGIDIGTTSTKAVLFSENGDVVQKESIGYPLYTPDISTAEQNPEEIFQAVIHTTARITKQHPEKRISFISFSSAM
HSVIAIDENDKPLTPCITWADNRSEGWAHKIKEELNGHEVYKRTGTPIHPMAPLSKIAWITNERKEIASKAKKYIGIKEY
IFKQLFNEYVIDYSLASATGMMNLKGLDWDEEALRIAGITPDHLSKLVPTTEIFQHCSPEIAIQMGIDPETPFVIGASDG
VLSNLGVNAIKKGEIAVTIGTSGAIRTIIDKPQTDEKGRIFCYALTDKHWVIGGPVNNGGIVLRWIRDEFASSEIETATR
LGIDPYDVLTKIAQRVRPGSDGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECM
DGPVTRIQATGGFARSEVWRQMMSDIFESEVVVPESYESSCLGACILGLYATGKIDSFDAVSDMIGSTYRHTPIEDSAKE
YRTLMPIFINLSRLLENQYTQIADYQRGLITHK

Sequences:

>Translated_513_residues
MTSYMLGIDIGTTSTKAVLFSENGDVVQKESIGYPLYTPDISTAEQNPEEIFQAVIHTTARITKQHPEKRISFISFSSAM
HSVIAIDENDKPLTPCITWADNRSEGWAHKIKEELNGHEVYKRTGTPIHPMAPLSKIAWITNERKEIASKAKKYIGIKEY
IFKQLFNEYVIDYSLASATGMMNLKGLDWDEEALRIAGITPDHLSKLVPTTEIFQHCSPEIAIQMGIDPETPFVIGASDG
VLSNLGVNAIKKGEIAVTIGTSGAIRTIIDKPQTDEKGRIFCYALTDKHWVIGGPVNNGGIVLRWIRDEFASSEIETATR
LGIDPYDVLTKIAQRVRPGSDGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECM
DGPVTRIQATGGFARSEVWRQMMSDIFESEVVVPESYESSCLGACILGLYATGKIDSFDAVSDMIGSTYRHTPIEDSAKE
YRTLMPIFINLSRLLENQYTQIADYQRGLITHK
>Mature_512_residues
TSYMLGIDIGTTSTKAVLFSENGDVVQKESIGYPLYTPDISTAEQNPEEIFQAVIHTTARITKQHPEKRISFISFSSAMH
SVIAIDENDKPLTPCITWADNRSEGWAHKIKEELNGHEVYKRTGTPIHPMAPLSKIAWITNERKEIASKAKKYIGIKEYI
FKQLFNEYVIDYSLASATGMMNLKGLDWDEEALRIAGITPDHLSKLVPTTEIFQHCSPEIAIQMGIDPETPFVIGASDGV
LSNLGVNAIKKGEIAVTIGTSGAIRTIIDKPQTDEKGRIFCYALTDKHWVIGGPVNNGGIVLRWIRDEFASSEIETATRL
GIDPYDVLTKIAQRVRPGSDGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMD
GPVTRIQATGGFARSEVWRQMMSDIFESEVVVPESYESSCLGACILGLYATGKIDSFDAVSDMIGSTYRHTPIEDSAKEY
RTLMPIFINLSRLLENQYTQIADYQRGLITHK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family

Homologues:

Organism=Homo sapiens, GI41393575, Length=448, Percent_Identity=24.1071428571429, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI42794763, Length=462, Percent_Identity=23.3766233766234, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI189409120, Length=462, Percent_Identity=23.3766233766234, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI4504007, Length=462, Percent_Identity=23.3766233766234, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI18860918, Length=423, Percent_Identity=21.9858156028369, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI88196792, Length=285, Percent_Identity=25.9649122807018, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789987, Length=425, Percent_Identity=28, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1787789, Length=543, Percent_Identity=24.8618784530387, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1790361, Length=495, Percent_Identity=25.8585858585859, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1790005, Length=496, Percent_Identity=23.7903225806452, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789168, Length=481, Percent_Identity=20.7900207900208, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789138, Length=505, Percent_Identity=24.3564356435644, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=498, Percent_Identity=23.0923694779116, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321755, Length=417, Percent_Identity=25.4196642685851, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864214, Length=475, Percent_Identity=23.5789473684211, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24655555, Length=441, Percent_Identity=24.4897959183673, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24655560, Length=441, Percent_Identity=24.4897959183673, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24655570, Length=441, Percent_Identity=24.4897959183673, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24655574, Length=441, Percent_Identity=24.4897959183673, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24655565, Length=441, Percent_Identity=24.4897959183673, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24654573, Length=399, Percent_Identity=23.8095238095238, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656367, Length=485, Percent_Identity=21.4432989690722, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357867, Length=496, Percent_Identity=21.3709677419355, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24656372, Length=301, Percent_Identity=24.5847176079734, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GNTK_BACSU (P12011)

Other databases:

- EMBL:   J02584
- EMBL:   AB005554
- EMBL:   AL009126
- PIR:   B26190
- RefSeq:   NP_391886.1
- ProteinModelPortal:   P12011
- SMR:   P12011
- EnsemblBacteria:   EBBACT00000000301
- GeneID:   937713
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU40060
- NMPDR:   fig|224308.1.peg.4012
- GenoList:   BSU40060
- GeneTree:   EBGT00050000001374
- HOGENOM:   HBG511469
- OMA:   FINLSRA
- PhylomeDB:   P12011
- ProtClustDB:   CLSK561418
- BioCyc:   BSUB:BSU40060-MONOMER
- BRENDA:   2.7.1.12
- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002
- PANTHER:   PTHR10196
- TIGRFAMs:   TIGR01314

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N

EC number: =2.7.1.12

Molecular weight: Translated: 57170; Mature: 57039

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00933 FGGY_KINASES_1; PS00445 FGGY_KINASES_2

Important sites: BINDING 16-16 BINDING 261-261 BINDING 300-300

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYMLGIDIGTTSTKAVLFSENGDVVQKESIGYPLYTPDISTAEQNPEEIFQAVIHTTA
CCCEEEEEEECCCCCEEEEEECCCCEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
RITKQHPEKRISFISFSSAMHSVIAIDENDKPLTPCITWADNRSEGWAHKIKEELNGHEV
HHHHHCHHHHHHHHHHHHHHCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHCCCHHH
YKRTGTPIHPMAPLSKIAWITNERKEIASKAKKYIGIKEYIFKQLFNEYVIDYSLASATG
HHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
MMNLKGLDWDEEALRIAGITPDHLSKLVPTTEIFQHCSPEIAIQMGIDPETPFVIGASDG
CCEECCCCCCHHHEEEECCCHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCCEEEECCCC
VLSNLGVNAIKKGEIAVTIGTSGAIRTIIDKPQTDEKGRIFCYALTDKHWVIGGPVNNGG
HHHHCCCCCEECCCEEEEECCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCC
IVLRWIRDEFASSEIETATRLGIDPYDVLTKIAQRVRPGSDGLLFHPYLAGERAPLWNPD
EEEEEEHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCC
VRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSEVWR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
QMMSDIFESEVVVPESYESSCLGACILGLYATGKIDSFDAVSDMIGSTYRHTPIEDSAKE
HHHHHHHHCCEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHH
YRTLMPIFINLSRLLENQYTQIADYQRGLITHK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TSYMLGIDIGTTSTKAVLFSENGDVVQKESIGYPLYTPDISTAEQNPEEIFQAVIHTTA
CCEEEEEEECCCCCEEEEEECCCCEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHH
RITKQHPEKRISFISFSSAMHSVIAIDENDKPLTPCITWADNRSEGWAHKIKEELNGHEV
HHHHHCHHHHHHHHHHHHHHCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHCCCHHH
YKRTGTPIHPMAPLSKIAWITNERKEIASKAKKYIGIKEYIFKQLFNEYVIDYSLASATG
HHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
MMNLKGLDWDEEALRIAGITPDHLSKLVPTTEIFQHCSPEIAIQMGIDPETPFVIGASDG
CCEECCCCCCHHHEEEECCCHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCCEEEECCCC
VLSNLGVNAIKKGEIAVTIGTSGAIRTIIDKPQTDEKGRIFCYALTDKHWVIGGPVNNGG
HHHHCCCCCEECCCEEEEECCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCC
IVLRWIRDEFASSEIETATRLGIDPYDVLTKIAQRVRPGSDGLLFHPYLAGERAPLWNPD
EEEEEEHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCC
VRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSEVWR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
QMMSDIFESEVVVPESYESSCLGACILGLYATGKIDSFDAVSDMIGSTYRHTPIEDSAKE
HHHHHHHHCCEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHH
YRTLMPIFINLSRLLENQYTQIADYQRGLITHK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377