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The map label for this gene is iolR

Identifier: 16081028

GI number: 16081028

Start: 4084799

End: 4085554

Strand: Direct

Name: iolR

Synonym: BSU39770

Alternate gene names: 16081028

Gene position: 4084799-4085554 (Clockwise)

Preceding gene: 255767847

Following gene: 16081029

Centisome position: 96.9

GC content: 41.93

Gene sequence:

>756_bases
ATGAAACTGATGCGGATTCAGGAAATGGAGGAGTACATTTTATCGCATGGCACTGTTTCCTTAGATGAGCTGTGCCAGGT
GTTCAATGTCTCCAAAAACACAGTCAGACGTGATATCAACAAGCTAACAGAAAAGGGTGCGATTGAAAAAGTATACGGCG
GCGTAACATCTATTGAAAAAACCGCATTAGTTCCTTTTGAAAATCGCACCATTCAGCACCAGGATGAAAAAACAAAAATC
GCCCATTATGCTTCCCGATTTATTGAAGATCACGATTTGGTCTTCATTGATTCAGGAACGACGACAAAGTCTATTCTTGA
TACGCTTGATCCAGCCAAAAATGTCACCATCTTAACCAACAGTTTAGACATTATCAATGCGGCGTCAGCTTTGAAGAATA
TCAACTTAATCATTATCGGAAACAACTATAAGAGAAAAACCCGCTCCTTTGTCGGCATGGACGACCCGGCTATGCTTGAT
AAGTACAATATCAACAAAGCCTTTATGTCCGCTACCGGAACGACGCTGACTCACGGATTGACCAATTCGGATCTGCTGGA
GTATGAAATTAAAAAGAGGATTTCAGAAAAAGCAAAAGAAGTGTATCTATTGGCTGACCATTCTAAATTCGGAAAATCAA
CGCTTCTGACGTATGCACCGTTTGACAGGCTGCATTGCATTGTGACCTCTCAGCCATTAGACGACGAGTACACGCAGTAC
TGCAATGAGCATCAAATCGGCATTCATCTGGCCTAA

Upstream 100 bases:

>100_bases
AGATATACACCGATGTTATCATTTTTAAGCAACTATTGATTAACTTTTGGTTTTTATTATATATTTATGTTACGTAAAGA
TTCAAGAAGGAGTTTTTTAT

Downstream 100 bases:

>100_bases
CGTTTACAATAGTGTTGAGAGTCTATCATCCATTTTATTCTAGGAGGCAGATCATGAAAAAAGCGAAGCTCGGAAAATCA
GACTTGCAGGTATTCCCTAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKLMRIQEMEEYILSHGTVSLDELCQVFNVSKNTVRRDINKLTEKGAIEKVYGGVTSIEKTALVPFENRTIQHQDEKTKI
AHYASRFIEDHDLVFIDSGTTTKSILDTLDPAKNVTILTNSLDIINAASALKNINLIIIGNNYKRKTRSFVGMDDPAMLD
KYNINKAFMSATGTTLTHGLTNSDLLEYEIKKRISEKAKEVYLLADHSKFGKSTLLTYAPFDRLHCIVTSQPLDDEYTQY
CNEHQIGIHLA

Sequences:

>Translated_251_residues
MKLMRIQEMEEYILSHGTVSLDELCQVFNVSKNTVRRDINKLTEKGAIEKVYGGVTSIEKTALVPFENRTIQHQDEKTKI
AHYASRFIEDHDLVFIDSGTTTKSILDTLDPAKNVTILTNSLDIINAASALKNINLIIIGNNYKRKTRSFVGMDDPAMLD
KYNINKAFMSATGTTLTHGLTNSDLLEYEIKKRISEKAKEVYLLADHSKFGKSTLLTYAPFDRLHCIVTSQPLDDEYTQY
CNEHQIGIHLA
>Mature_251_residues
MKLMRIQEMEEYILSHGTVSLDELCQVFNVSKNTVRRDINKLTEKGAIEKVYGGVTSIEKTALVPFENRTIQHQDEKTKI
AHYASRFIEDHDLVFIDSGTTTKSILDTLDPAKNVTILTNSLDIINAASALKNINLIIIGNNYKRKTRSFVGMDDPAMLD
KYNINKAFMSATGTTLTHGLTNSDLLEYEIKKRISEKAKEVYLLADHSKFGKSTLLTYAPFDRLHCIVTSQPLDDEYTQY
CNEHQIGIHLA

Specific function: Iol operon repressor

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789059, Length=239, Percent_Identity=30.5439330543933, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788069, Length=246, Percent_Identity=29.6747967479675, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789829, Length=240, Percent_Identity=26.25, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI226510968, Length=238, Percent_Identity=29.8319327731092, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787540, Length=249, Percent_Identity=25.7028112449799, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789519, Length=233, Percent_Identity=25.3218884120172, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790753, Length=218, Percent_Identity=28.4403669724771, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082344, Length=201, Percent_Identity=26.865671641791, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1790635, Length=246, Percent_Identity=26.8292682926829, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=26.9230769230769, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787063, Length=246, Percent_Identity=24.7967479674797, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLR_BACSU (P46337)

Other databases:

- EMBL:   AB005554
- EMBL:   AL009126
- PIR:   C69646
- RefSeq:   NP_391856.1
- ProteinModelPortal:   P46337
- SMR:   P46337
- EnsemblBacteria:   EBBACT00000003139
- GeneID:   937635
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU39770
- NMPDR:   fig|224308.1.peg.3982
- GenoList:   BSU39770
- GeneTree:   EBGT00050000001025
- HOGENOM:   HBG694151
- OMA:   LLTYAPF
- PhylomeDB:   P46337
- ProtClustDB:   CLSK2752573
- BioCyc:   BSUB:BSU39770-MONOMER
- GO:   GO:0005622
- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00037
- SMART:   SM00420

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 28406; Mature: 28406

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMRIQEMEEYILSHGTVSLDELCQVFNVSKNTVRRDINKLTEKGAIEKVYGGVTSIEK
CCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCHHHCCC
TALVPFENRTIQHQDEKTKIAHYASRFIEDHDLVFIDSGTTTKSILDTLDPAKNVTILTN
EEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCEEEEEC
SLDIINAASALKNINLIIIGNNYKRKTRSFVGMDDPAMLDKYNINKAFMSATGTTLTHGL
CCHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHCCCCCCCCCC
TNSDLLEYEIKKRISEKAKEVYLLADHSKFGKSTLLTYAPFDRLHCIVTSQPLDDEYTQY
CCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHH
CNEHQIGIHLA
CCCCCEEEEEC
>Mature Secondary Structure
MKLMRIQEMEEYILSHGTVSLDELCQVFNVSKNTVRRDINKLTEKGAIEKVYGGVTSIEK
CCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHCCHHHCCC
TALVPFENRTIQHQDEKTKIAHYASRFIEDHDLVFIDSGTTTKSILDTLDPAKNVTILTN
EEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHCCCCCCEEEEEC
SLDIINAASALKNINLIIIGNNYKRKTRSFVGMDDPAMLDKYNINKAFMSATGTTLTHGL
CCHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHCCCCCCCCCC
TNSDLLEYEIKKRISEKAKEVYLLADHSKFGKSTLLTYAPFDRLHCIVTSQPLDDEYTQY
CCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHH
CNEHQIGIHLA
CCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377