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The map label for this gene is ywhC

Identifier: 16080805

GI number: 16080805

Start: 3852718

End: 3853377

Strand: Reverse

Name: ywhC

Synonym: BSU37530

Alternate gene names: 16080805

Gene position: 3853377-3852718 (Counterclockwise)

Preceding gene: 16080807

Following gene: 16080804

Centisome position: 91.41

GC content: 47.42

Gene sequence:

>660_bases
TTGGACCGTTTTTTATATTATCCGTTATCTTTAATGCCATACCTCGTCATCACGCTAATTGTGTCGTTTACGATGCACGA
GCTTGCCCACGCTTATGTCGCATACAAATTCGGTGACGATACGGCGAAAAAACAAGGAAGACTGACGCTGAATCCCATTA
AACACCTTGATCCGTTCGGAACCATTTTGATTCTGGTGGCCGGATTCGGGTGGGCGCGCCCCATTCCCGTGAATCGCCGT
TTCTTTAAGAAACCCCGGCTTGCTGGTGTGCTCGTATCTATAGCCGGGCCCGTCAGTAACCTGATTCTTGCGTTTATTGG
TTTCTTTTTGTTAGTGTTGATGCATGCGTACGGAATGGAAATGCTTGCGGCGTTCAGCACGGGGCTGGATCAGTTTTTTT
CTATTTGGATACAGCTGAATCTTGTCTTGTTTTTATTTAATCTGCTGCCGCTTCCTCCGCTCGATGGCTATCGAATTATA
GAAGATCTCGTTCCGCCGGGCGTGCGTGCCAAAATGACGCAGGCGGAGAGCTACGGCTTTATCGTATTTTTGGTGCTGTT
TGTGACACCGCTAGGATCTTACGTGCTGTGGCCGATGCTCAATGCAGGAAGAGATTCGATTTTAAAGCTGTTTTCAGCGA
TATTTCAACCGCTTTTGTAG

Upstream 100 bases:

>100_bases
AATCCTCCTTTATCTCGTTTCCTCTCTTTAGAAAAAGAGGCTTCTTATAGTATACTGAATAAAGTAAATTCTTGCATTTT
GAGAAAGAGGGATATCTCAC

Downstream 100 bases:

>100_bases
GAGGTAGAACTTCATGGAAGAAAAAAAGAAAAAATCAATCGGGTTTAATATTATCAAAAGTGATCCGACAGACGGACACG
GCGGTTTTGGCGTAGGGGCA

Product: metal-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MDRFLYYPLSLMPYLVITLIVSFTMHELAHAYVAYKFGDDTAKKQGRLTLNPIKHLDPFGTILILVAGFGWARPIPVNRR
FFKKPRLAGVLVSIAGPVSNLILAFIGFFLLVLMHAYGMEMLAAFSTGLDQFFSIWIQLNLVLFLFNLLPLPPLDGYRII
EDLVPPGVRAKMTQAESYGFIVFLVLFVTPLGSYVLWPMLNAGRDSILKLFSAIFQPLL

Sequences:

>Translated_219_residues
MDRFLYYPLSLMPYLVITLIVSFTMHELAHAYVAYKFGDDTAKKQGRLTLNPIKHLDPFGTILILVAGFGWARPIPVNRR
FFKKPRLAGVLVSIAGPVSNLILAFIGFFLLVLMHAYGMEMLAAFSTGLDQFFSIWIQLNLVLFLFNLLPLPPLDGYRII
EDLVPPGVRAKMTQAESYGFIVFLVLFVTPLGSYVLWPMLNAGRDSILKLFSAIFQPLL
>Mature_219_residues
MDRFLYYPLSLMPYLVITLIVSFTMHELAHAYVAYKFGDDTAKKQGRLTLNPIKHLDPFGTILILVAGFGWARPIPVNRR
FFKKPRLAGVLVSIAGPVSNLILAFIGFFLLVLMHAYGMEMLAAFSTGLDQFFSIWIQLNLVLFLFNLLPLPPLDGYRII
EDLVPPGVRAKMTQAESYGFIVFLVLFVTPLGSYVLWPMLNAGRDSILKLFSAIFQPLL

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M50B family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWHC_BACSU (P70995)

Other databases:

- EMBL:   Z80360
- EMBL:   AL009126
- PIR:   D70057
- RefSeq:   NP_391633.1
- ProteinModelPortal:   P70995
- SMR:   P70995
- EnsemblBacteria:   EBBACT00000003130
- GeneID:   937099
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU37530
- NMPDR:   fig|224308.1.peg.3759
- GenoList:   BSU37530
- GeneTree:   EBGT00050000000843
- HOGENOM:   HBG581577
- OMA:   PLAGSQF
- ProtClustDB:   CLSK888063
- BioCyc:   BSUB:BSU37530-MONOMER
- GO:   GO:0006508
- InterPro:   IPR008915

Pfam domain/function: PF02163 Peptidase_M50

EC number: NA

Molecular weight: Translated: 24704; Mature: 24704

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 27-27

Signals:

None

Transmembrane regions:

HASH(0x13195674)-; HASH(0x1305b934)-; HASH(0x12bb7c0c)-; HASH(0x12a3828c)-; HASH(0x130a1850)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFLYYPLSLMPYLVITLIVSFTMHELAHAYVAYKFGDDTAKKQGRLTLNPIKHLDPFG
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHCCCEEECHHHHCCHHH
TILILVAGFGWARPIPVNRRFFKKPRLAGVLVSIAGPVSNLILAFIGFFLLVLMHAYGME
HHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAAFSTGLDQFFSIWIQLNLVLFLFNLLPLPPLDGYRIIEDLVPPGVRAKMTQAESYGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCHH
IVFLVLFVTPLGSYVLWPMLNAGRDSILKLFSAIFQPLL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDRFLYYPLSLMPYLVITLIVSFTMHELAHAYVAYKFGDDTAKKQGRLTLNPIKHLDPFG
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHCCCEEECHHHHCCHHH
TILILVAGFGWARPIPVNRRFFKKPRLAGVLVSIAGPVSNLILAFIGFFLLVLMHAYGME
HHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAAFSTGLDQFFSIWIQLNLVLFLFNLLPLPPLDGYRIIEDLVPPGVRAKMTQAESYGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCHH
IVFLVLFVTPLGSYVLWPMLNAGRDSILKLFSAIFQPLL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377