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The map label for this gene is glpX

Identifier: 16080762

GI number: 16080762

Start: 3805090

End: 3806055

Strand: Reverse

Name: glpX

Synonym: BSU37090

Alternate gene names: 16080762

Gene position: 3806055-3805090 (Counterclockwise)

Preceding gene: 255767788

Following gene: 255767787

Centisome position: 90.28

GC content: 50.0

Gene sequence:

>966_bases
ATGGAAAGAAGTTTATCAATGGAATTGGTACGTGTGACAGAAGCTGCGGCATTGGCATCAGCAAGATGGATGGGCCGGGG
AAAAAAAGATGAGGCTGATGAAGCGGCAACAAGTGCAATGAGAGACGTTTTTGATACAGTGCCGATGAAAGGGACCGTTG
TAATCGGTGAAGGGGAAATGGACGAAGCGCCAATGCTGTATATCGGGGAAAAACTCGGAAACGGGTACGGCCCTCGCGTT
GATGTCGCAGTTGACCCTCTTGAAGGCACAAACATCTTAGCAAGCGGCGGCTGGAACGCGCTGACGGTTATCGCGGTCGC
AGACCATGGCACGCTTCTGAATGCTCCTGACATGTATATGCAAAAAATCGCAGTCGGTCCGGAAGCGGTGGGCTGCATTG
ACATCGAAGCACCTGTCATTGACAACCTTAAAGCGGTGGCAAAAGCGAAAAACAAGGACGTTGAGGACGTCGTTGCCACA
ATTTTAAACCGTGAAAGACACGCAAAAATCATTTCCGAGCTTCGTGAGGCCGGCGCCAGAATCAAATTGATCAATGACGG
CGATGTCGCAGGCGCCATCAACACGGCTTTCGACCACACGGGCGTTGATATCCTGTTCGGATCAGGCGGCGCTCCTGAGG
GTGTGCTTTCCGCTGTTGCGCTAAAAGCACTCGGCGGAGAAATCATTGGTAAACTTCTTCCGCAAAGCGAAGAAGAAATC
ACTCGCTGTCACAAAATGGGCCTTGATTTAAGCAAAGTGCTTCGCATGGAAGACCTTGTGAAGGGTGATGACGCGATTTT
TGCAGCTACAGGGGTTACTGACGGCGAGCTGTTAAAAGGAGTTCAATTCAAAGGCTCTGTCGGTACAACTGAAAGCTTAG
TTATCCGTGCAAAATCGGGCACTGTTCGTTTCGTTGACGGCAGACACAGCTTGAAAAAGAAACCAAATCTTGTAATCCGT
CCATAA

Upstream 100 bases:

>100_bases
GGGGCTTGGAGCGACAATTTGGCGTGAAAGAATGACTGACGAAGAAATAGAACAGCTTCAAAATTCATAATGGTTTCTTG
TGAGAGGAGATCGTGTTGAA

Downstream 100 bases:

>100_bases
CAAACAGAAAAAGCGGGTGTGAGCCCGCTTTAACTTTTGCAGAAAAGCGTCAACTCTATCAATTCCGTGTCAAAACCTTA
TTTCAGTTGAATAATTTTTT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MERSLSMELVRVTEAAALASARWMGRGKKDEADEAATSAMRDVFDTVPMKGTVVIGEGEMDEAPMLYIGEKLGNGYGPRV
DVAVDPLEGTNILASGGWNALTVIAVADHGTLLNAPDMYMQKIAVGPEAVGCIDIEAPVIDNLKAVAKAKNKDVEDVVAT
ILNRERHAKIISELREAGARIKLINDGDVAGAINTAFDHTGVDILFGSGGAPEGVLSAVALKALGGEIIGKLLPQSEEEI
TRCHKMGLDLSKVLRMEDLVKGDDAIFAATGVTDGELLKGVQFKGSVGTTESLVIRAKSGTVRFVDGRHSLKKKPNLVIR
P

Sequences:

>Translated_321_residues
MERSLSMELVRVTEAAALASARWMGRGKKDEADEAATSAMRDVFDTVPMKGTVVIGEGEMDEAPMLYIGEKLGNGYGPRV
DVAVDPLEGTNILASGGWNALTVIAVADHGTLLNAPDMYMQKIAVGPEAVGCIDIEAPVIDNLKAVAKAKNKDVEDVVAT
ILNRERHAKIISELREAGARIKLINDGDVAGAINTAFDHTGVDILFGSGGAPEGVLSAVALKALGGEIIGKLLPQSEEEI
TRCHKMGLDLSKVLRMEDLVKGDDAIFAATGVTDGELLKGVQFKGSVGTTESLVIRAKSGTVRFVDGRHSLKKKPNLVIR
P
>Mature_321_residues
MERSLSMELVRVTEAAALASARWMGRGKKDEADEAATSAMRDVFDTVPMKGTVVIGEGEMDEAPMLYIGEKLGNGYGPRV
DVAVDPLEGTNILASGGWNALTVIAVADHGTLLNAPDMYMQKIAVGPEAVGCIDIEAPVIDNLKAVAKAKNKDVEDVVAT
ILNRERHAKIISELREAGARIKLINDGDVAGAINTAFDHTGVDILFGSGGAPEGVLSAVALKALGGEIIGKLLPQSEEEI
TRCHKMGLDLSKVLRMEDLVKGDDAIFAATGVTDGELLKGVQFKGSVGTTESLVIRAKSGTVRFVDGRHSLKKKPNLVIR
P

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family

Homologues:

Organism=Escherichia coli, GI1790360, Length=327, Percent_Identity=49.8470948012232, Blast_Score=321, Evalue=4e-89,
Organism=Escherichia coli, GI1789298, Length=319, Percent_Identity=42.9467084639498, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPX_BACSU (Q03224)

Other databases:

- EMBL:   M97678
- EMBL:   Z49782
- EMBL:   AL009126
- PIR:   S55429
- RefSeq:   NP_391590.1
- ProteinModelPortal:   Q03224
- SMR:   Q03224
- EnsemblBacteria:   EBBACT00000003593
- GeneID:   937035
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU37090
- NMPDR:   fig|224308.1.peg.3716
- GenoList:   BSU37090
- GeneTree:   EBGT00050000000581
- HOGENOM:   HBG284837
- OMA:   GTVRFIE
- PhylomeDB:   Q03224
- ProtClustDB:   PRK09479
- BioCyc:   BSUB:BSU37090-MONOMER
- GO:   GO:0006094
- InterPro:   IPR004464
- PIRSF:   PIRSF004532
- TIGRFAMs:   TIGR00330

Pfam domain/function: PF03320 FBPase_glpX

EC number: =3.1.3.11

Molecular weight: Translated: 33952; Mature: 33952

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: BINDING 119-119 BINDING 210-210

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSLSMELVRVTEAAALASARWMGRGKKDEADEAATSAMRDVFDTVPMKGTVVIGEGEM
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCC
DEAPMLYIGEKLGNGYGPRVDVAVDPLEGTNILASGGWNALTVIAVADHGTLLNAPDMYM
CCCCEEEEEHHHCCCCCCEEEEEECCCCCCEEEECCCCCEEEEEEEECCCCEECCHHHHH
QKIAVGPEAVGCIDIEAPVIDNLKAVAKAKNKDVEDVVATILNRERHAKIISELREAGAR
HHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCE
IKLINDGDVAGAINTAFDHTGVDILFGSGGAPEGVLSAVALKALGGEIIGKLLPQSEEEI
EEEEECCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
TRCHKMGLDLSKVLRMEDLVKGDDAIFAATGVTDGELLKGVQFKGSVGTTESLVIRAKSG
HHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCEEECCCCCCCCEEEEEECCC
TVRFVDGRHSLKKKPNLVIRP
EEEEECCCHHHCCCCCEEECC
>Mature Secondary Structure
MERSLSMELVRVTEAAALASARWMGRGKKDEADEAATSAMRDVFDTVPMKGTVVIGEGEM
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCC
DEAPMLYIGEKLGNGYGPRVDVAVDPLEGTNILASGGWNALTVIAVADHGTLLNAPDMYM
CCCCEEEEEHHHCCCCCCEEEEEECCCCCCEEEECCCCCEEEEEEEECCCCEECCHHHHH
QKIAVGPEAVGCIDIEAPVIDNLKAVAKAKNKDVEDVVATILNRERHAKIISELREAGAR
HHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCE
IKLINDGDVAGAINTAFDHTGVDILFGSGGAPEGVLSAVALKALGGEIIGKLLPQSEEEI
EEEEECCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
TRCHKMGLDLSKVLRMEDLVKGDDAIFAATGVTDGELLKGVQFKGSVGTTESLVIRAKSG
HHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCEEECCCCCCCCEEEEEECCC
TVRFVDGRHSLKKKPNLVIRP
EEEEECCCHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377