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The map label for this gene is glcR

Identifier: 16080683

GI number: 16080683

Start: 3739206

End: 3739982

Strand: Reverse

Name: glcR

Synonym: BSU36300

Alternate gene names: 16080683

Gene position: 3739982-3739206 (Counterclockwise)

Preceding gene: 255767782

Following gene: 16080682

Centisome position: 88.72

GC content: 46.59

Gene sequence:

>777_bases
GTGTACCAAGAAGAAAGATTAGTAGCGATTTTGGATTTTTTAAAACAGCATAACCGAATTACAACGGAGCAGATCTGTAC
GCTCCTGCAAGTGTCAAGGGATACAGCGCGACGAGATCTTGTGAAACTTGAGGAACAGAATGCCATCATCCGCACAAGAG
GCGGCGCCATTTTACCGACTGTGCATCAGAAAATTCAAAGCTATTCCGGCCGCCTGAAAACAGTGTCTGAGGAAAAAAAT
AAGATCGGCAGGCTTGCAGCATCGCTTATTCATGATGGAGACCGGGTGATTTTAGACGCCTCTACAACTGTTCAGGCATG
TGCAAAGCATTTGAATGCGGTTGATTGTACCGTAATCACCAATTCGATTAATCTTGCGGATGTGCTGTCCGATAAAGAGG
GAATTGAAATTTATCTGCTGGGAGGCAAGCTGGAAAAGGAGCACCGCTTTCTGTACGGGTCCTCTGTGATTGAAAAGCTC
TCAAGCTACCATGTTGATAAAGCGCTGATTGGTGTGGTCGGCATTTCCGAACATGGCATTACAATTGCGCATGAAGAGGA
TGGCATGGTGAAGCGGAAAATGATACAGCAGGCAAAGCAGGTAATTGCGCTTGCAGACCATTCTAAGCTGGGCAGCACCA
GTTTTTATCAGTATGCGGAGCTGAATGAAATCGACCTCTTGATTACAGACAGGCTGCCGAATCAGGCATTTTGTGACTTG
CTTGACCGAAACGGCGTTGAGCTTCTCGTGACAGAGCAGGATGAAGGAAAGGACTGA

Upstream 100 bases:

>100_bases
CTCGACGCATTTTTACTTAAAATCACTTATTAATGTTGAATAAAATCAAATAAAAACTTATAATTACTTATAAATGATTG
CTGAGAAAAGGAATGAGGGC

Downstream 100 bases:

>100_bases
CAAACGTGAAATTAATTGCGATTGACTTAGATGGAACCTTACTCAACAGCAAGCATCAGGTAAGCTTGGAAAATGAAAAC
GCACTGCGGCAGGCGCAGCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MYQEERLVAILDFLKQHNRITTEQICTLLQVSRDTARRDLVKLEEQNAIIRTRGGAILPTVHQKIQSYSGRLKTVSEEKN
KIGRLAASLIHDGDRVILDASTTVQACAKHLNAVDCTVITNSINLADVLSDKEGIEIYLLGGKLEKEHRFLYGSSVIEKL
SSYHVDKALIGVVGISEHGITIAHEEDGMVKRKMIQQAKQVIALADHSKLGSTSFYQYAELNEIDLLITDRLPNQAFCDL
LDRNGVELLVTEQDEGKD

Sequences:

>Translated_258_residues
MYQEERLVAILDFLKQHNRITTEQICTLLQVSRDTARRDLVKLEEQNAIIRTRGGAILPTVHQKIQSYSGRLKTVSEEKN
KIGRLAASLIHDGDRVILDASTTVQACAKHLNAVDCTVITNSINLADVLSDKEGIEIYLLGGKLEKEHRFLYGSSVIEKL
SSYHVDKALIGVVGISEHGITIAHEEDGMVKRKMIQQAKQVIALADHSKLGSTSFYQYAELNEIDLLITDRLPNQAFCDL
LDRNGVELLVTEQDEGKD
>Mature_258_residues
MYQEERLVAILDFLKQHNRITTEQICTLLQVSRDTARRDLVKLEEQNAIIRTRGGAILPTVHQKIQSYSGRLKTVSEEKN
KIGRLAASLIHDGDRVILDASTTVQACAKHLNAVDCTVITNSINLADVLSDKEGIEIYLLGGKLEKEHRFLYGSSVIEKL
SSYHVDKALIGVVGISEHGITIAHEEDGMVKRKMIQQAKQVIALADHSKLGSTSFYQYAELNEIDLLITDRLPNQAFCDL
LDRNGVELLVTEQDEGKD

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789829, Length=250, Percent_Identity=30.8, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=30.7086614173228, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788069, Length=253, Percent_Identity=32.0158102766798, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=32.03125, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789059, Length=260, Percent_Identity=30, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=30.8695652173913, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=26.1904761904762, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790753, Length=252, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790635, Length=251, Percent_Identity=25.8964143426295, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787063, Length=241, Percent_Identity=24.896265560166, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): GLCR_BACSU (P94591)

Other databases:

- EMBL:   Z83337
- EMBL:   AL009126
- PIR:   C69632
- RefSeq:   NP_391511.1
- ProteinModelPortal:   P94591
- SMR:   P94591
- EnsemblBacteria:   EBBACT00000002488
- GeneID:   936908
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU36300
- NMPDR:   fig|224308.1.peg.3637
- GenoList:   BSU36300
- GeneTree:   EBGT00050000001025
- HOGENOM:   HBG694151
- OMA:   SINLAHT
- PhylomeDB:   P94591
- ProtClustDB:   CLSK2517416
- BioCyc:   BSUB:BSU36300-MONOMER
- GO:   GO:0005622
- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00037
- SMART:   SM00420

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 28821; Mature: 28821

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQEERLVAILDFLKQHNRITTEQICTLLQVSRDTARRDLVKLEEQNAIIRTRGGAILPT
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECHH
VHQKIQSYSGRLKTVSEEKNKIGRLAASLIHDGDRVILDASTTVQACAKHLNAVDCTVIT
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCEEEEEEE
NSINLADVLSDKEGIEIYLLGGKLEKEHRFLYGSSVIEKLSSYHVDKALIGVVGISEHGI
CCCCHHHHHCCCCCCEEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCE
TIAHEEDGMVKRKMIQQAKQVIALADHSKLGSTSFYQYAELNEIDLLITDRLPNQAFCDL
EEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEECCCCCHHHHHH
LDRNGVELLVTEQDEGKD
HCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MYQEERLVAILDFLKQHNRITTEQICTLLQVSRDTARRDLVKLEEQNAIIRTRGGAILPT
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECHH
VHQKIQSYSGRLKTVSEEKNKIGRLAASLIHDGDRVILDASTTVQACAKHLNAVDCTVIT
HHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCEEEEEEE
NSINLADVLSDKEGIEIYLLGGKLEKEHRFLYGSSVIEKLSSYHVDKALIGVVGISEHGI
CCCCHHHHHCCCCCCEEEEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCE
TIAHEEDGMVKRKMIQQAKQVIALADHSKLGSTSFYQYAELNEIDLLITDRLPNQAFCDL
EEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEECCCCCHHHHHH
LDRNGVELLVTEQDEGKD
HCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377