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The map label for this gene is tagO

Identifier: 16080606

GI number: 16080606

Start: 3648654

End: 3649730

Strand: Reverse

Name: tagO

Synonym: BSU35530

Alternate gene names: 16080606

Gene position: 3649730-3648654 (Counterclockwise)

Preceding gene: 16080607

Following gene: 16080603

Centisome position: 86.58

GC content: 39.55

Gene sequence:

>1077_bases
ATGCTTGACGAACGCATGATTCGCATTGTTGTTGCGTTTATTGTCTCGCTGCTGACAGTTTTAATCATAACCCCAATCGT
AAAAAGGATTGCGATTAAAATAGGTGCAGTTGACCAGCCCAGCAATCGAAAAGTACATGACAAAATCATGCCCCGCATGG
GCGGGCTGGCCATATTTATCGGGGTGGTTGCAGGCGTGCTTGCATCCGGTATTTACACAGAAACAAGGATGACGGCAATT
ACAGTCGGAGCATTCATCATTATTGTGTTAGGTATTCTTGACGATAAATATCAATTAAGTGCAAAAGTTAAGTTTTTGAT
TCAATTAGGTGTAGCCATTATGATTGTAAGCACTGGCTTAAAAATGGACTTTTTCTCAGTACCTTTTTTAACAGAACGAT
TTGAGTTAGGATGGATGGCTTATCCGCTGACGGTATTATGGATTGTCGGCATCACGAACGCAATTAACCTGATTGATGGA
TTGGATGGCCTTGCTGCCGGTCTTTCTGTTATCGGCCTGTCAACGATTGCTGTCATGGCGCTATCCGGCGGAAAAGTGCT
CATTCTGTCACTCTCATTAGTCGTTATTGCCAGCACGCTGGGGTTTTTGTTTTACAACTTCCATCCGGCAAAAATCTTTA
TGGGAGATACGGGATCACTGTTTTTAGGGTATAGTATCTCGATTCTTTCATTATTAGGCCTGTATAAAAGTGTCACATTG
TTCAGTATCGTTATCCCGATTATTATATTAGGCGTACCGATTTTTGATACAACATTTGCTATCATCAGAAGAATATTAAA
CAAACAGCCGATTTCAGCGCCTGATAAGTCGCATATTCACCATAGACTGATGGCCTTTGGCCTTTCACATCGGATGTCGG
TCTTAGTTATTTATTTAATTGGATTTATTTTCAGTATCAGTGCGATTGTACTTAAAAGTGCCACAATTTGGCTTTCTTTG
TTTATTATCTTCATTTTGATTATTTTTATGCAAATCATAGCAGAAGTGACAGGACTCGTGAATGAAAAATTTAAGCCGTT
TACAAAGTTTTATAAACGGCTGGTGAAAAGGAATTAA

Upstream 100 bases:

>100_bases
TTTGATGAAGCTTGTTATAATAACTAAGGAGAAGGTATAATGGAAGGAACGGTTCTCTATATAAATAAAGACTTCATTTA
ATTCCAAAGGAGACTTCTTT

Downstream 100 bases:

>100_bases
AAACTCCGGCTTATGTGCCGGAGTTTTTTTCTGCGCAAAAATGCCCGATCCTCTAAAAGGACCGGGCATTTTTTAATAGG
ATGAATCAGTTGTTGAATTC

Product: UDP-N-acetylglucosamine:undecaprenyl-P N-acetylglucosaminyl-1-P transferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLDERMIRIVVAFIVSLLTVLIITPIVKRIAIKIGAVDQPSNRKVHDKIMPRMGGLAIFIGVVAGVLASGIYTETRMTAI
TVGAFIIIVLGILDDKYQLSAKVKFLIQLGVAIMIVSTGLKMDFFSVPFLTERFELGWMAYPLTVLWIVGITNAINLIDG
LDGLAAGLSVIGLSTIAVMALSGGKVLILSLSLVVIASTLGFLFYNFHPAKIFMGDTGSLFLGYSISILSLLGLYKSVTL
FSIVIPIIILGVPIFDTTFAIIRRILNKQPISAPDKSHIHHRLMAFGLSHRMSVLVIYLIGFIFSISAIVLKSATIWLSL
FIIFILIIFMQIIAEVTGLVNEKFKPFTKFYKRLVKRN

Sequences:

>Translated_358_residues
MLDERMIRIVVAFIVSLLTVLIITPIVKRIAIKIGAVDQPSNRKVHDKIMPRMGGLAIFIGVVAGVLASGIYTETRMTAI
TVGAFIIIVLGILDDKYQLSAKVKFLIQLGVAIMIVSTGLKMDFFSVPFLTERFELGWMAYPLTVLWIVGITNAINLIDG
LDGLAAGLSVIGLSTIAVMALSGGKVLILSLSLVVIASTLGFLFYNFHPAKIFMGDTGSLFLGYSISILSLLGLYKSVTL
FSIVIPIIILGVPIFDTTFAIIRRILNKQPISAPDKSHIHHRLMAFGLSHRMSVLVIYLIGFIFSISAIVLKSATIWLSL
FIIFILIIFMQIIAEVTGLVNEKFKPFTKFYKRLVKRN
>Mature_358_residues
MLDERMIRIVVAFIVSLLTVLIITPIVKRIAIKIGAVDQPSNRKVHDKIMPRMGGLAIFIGVVAGVLASGIYTETRMTAI
TVGAFIIIVLGILDDKYQLSAKVKFLIQLGVAIMIVSTGLKMDFFSVPFLTERFELGWMAYPLTVLWIVGITNAINLIDG
LDGLAAGLSVIGLSTIAVMALSGGKVLILSLSLVVIASTLGFLFYNFHPAKIFMGDTGSLFLGYSISILSLLGLYKSVTL
FSIVIPIIILGVPIFDTTFAIIRRILNKQPISAPDKSHIHHRLMAFGLSHRMSVLVIYLIGFIFSISAIVLKSATIWLSL
FIIFILIIFMQIIAEVTGLVNEKFKPFTKFYKRLVKRN

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family

Homologues:

Organism=Escherichia coli, GI1790218, Length=278, Percent_Identity=28.4172661870504, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786275, Length=257, Percent_Identity=30.3501945525292, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAGO_BACSU (O34753)

Other databases:

- EMBL:   AJ004803
- EMBL:   AL009126
- PIR:   B69721
- RefSeq:   NP_391433.1
- ProteinModelPortal:   O34753
- EnsemblBacteria:   EBBACT00000003612
- GeneID:   936757
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU35530
- NMPDR:   fig|224308.1.peg.3559
- GenoList:   BSU35530
- GeneTree:   EBGT00050000001191
- HOGENOM:   HBG708263
- OMA:   TPGKDHI
- PhylomeDB:   O34753
- ProtClustDB:   CLSK887963
- BioCyc:   BSUB:BSU35530-MONOMER
- BioCyc:   MetaCyc:MONOMER-8806
- InterPro:   IPR000715
- InterPro:   IPR018480
- PANTHER:   PTHR22926

Pfam domain/function: PF00953 Glycos_transf_4

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39364; Mature: 39364

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11edea10)-; HASH(0x128805f4)-; HASH(0x128dfa5c)-; HASH(0x118711a4)-; HASH(0x127fab98)-; HASH(0x114d3800)-; HASH(0x108618cc)-; HASH(0x121436c4)-; HASH(0x1063e1dc)-; HASH(0x12886188)-; HASH(0x12515e84)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDERMIRIVVAFIVSLLTVLIITPIVKRIAIKIGAVDQPSNRKVHDKIMPRMGGLAIFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHH
GVVAGVLASGIYTETRMTAITVGAFIIIVLGILDDKYQLSAKVKFLIQLGVAIMIVSTGL
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
KMDFFSVPFLTERFELGWMAYPLTVLWIVGITNAINLIDGLDGLAAGLSVIGLSTIAVMA
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LSGGKVLILSLSLVVIASTLGFLFYNFHPAKIFMGDTGSLFLGYSISILSLLGLYKSVTL
HCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FSIVIPIIILGVPIFDTTFAIIRRILNKQPISAPDKSHIHHRLMAFGLSHRMSVLVIYLI
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GFIFSISAIVLKSATIWLSLFIIFILIIFMQIIAEVTGLVNEKFKPFTKFYKRLVKRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCH
>Mature Secondary Structure
MLDERMIRIVVAFIVSLLTVLIITPIVKRIAIKIGAVDQPSNRKVHDKIMPRMGGLAIFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHH
GVVAGVLASGIYTETRMTAITVGAFIIIVLGILDDKYQLSAKVKFLIQLGVAIMIVSTGL
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
KMDFFSVPFLTERFELGWMAYPLTVLWIVGITNAINLIDGLDGLAAGLSVIGLSTIAVMA
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LSGGKVLILSLSLVVIASTLGFLFYNFHPAKIFMGDTGSLFLGYSISILSLLGLYKSVTL
HCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
FSIVIPIIILGVPIFDTTFAIIRRILNKQPISAPDKSHIHHRLMAFGLSHRMSVLVIYLI
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GFIFSISAIVLKSATIWLSLFIIFILIIFMQIIAEVTGLVNEKFKPFTKFYKRLVKRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377