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The map label for this gene is ftsX

Identifier: 16080578

GI number: 16080578

Start: 3623938

End: 3624828

Strand: Reverse

Name: ftsX

Synonym: BSU35250

Alternate gene names: 16080578

Gene position: 3624828-3623938 (Counterclockwise)

Preceding gene: 16080579

Following gene: 16080577

Centisome position: 85.99

GC content: 42.87

Gene sequence:

>891_bases
ATGATTAAAATTCTCGGGCGCCACTTGCGTGAGAGTTTTAAATCTCTCGGGAGAAACACATGGATGACATTTGCATCCAT
TAGTGCTGTAACCGTTACGCTGATTTTAGTCGGCGTGTTTTTAGTGATTATGCTGAATTTGAATAACATGGCCACGAATG
CAGAAAAACAAGTCGAAATCAAAGTGCTGATTGATCTGACTGCAGATCAGAAGGCACAGGACAAGCTTCAGAACGATATT
AAGGAACTGAAGGGCATTCAGAGTGTCACTTTTTCATCTAAAGAAAAAGAGCTTGACCAGCTGGTTGACAGTTTTGGTGA
CAGCGGAAAATCCCTGACAATGAAGGATCAGGAAAACCCGCTTAATGATGCGTTTGTCGTCAAAACGACAGATCCGCATG
ATACGCCGAACGTGGCGAAAAAGATCGAAAAAATGGATCATGTTTATAAAGTCACTTATGGAAAAGAAGAGGTCAGCCGT
TTGTTTAAAGTGGTCGGCGTTTCCCGCAACATCGGAATCGCGTTAATTATCGGCCTGGTATTTACGGCGATGTTCTTAAT
TTCCAACACCATTAAAATTACAATTTTCGCAAGAAGAAAAGAAATTGAAATCATGAAGCTTGTCGGCGCGACAAACTGGT
TTATCCGCTGGCCGTTTTTCCTTGAAGGATTGCTGCTAGGCGTATTCGGTTCTGTGATTCCGATTGCACTGGTGCTGAGC
ACTTACCAATACGTCATCGGATGGGTCGTTCCAAAGGTTCAAGGATCATTTGTCTCTCTTCTTCCTTATAATCCATTTGT
ATTCCAAGTTTCGCTAGTGCTGATTGCAATCGGCGCAGTAATTGGAGTATGGGGAAGTCTGACTTCCATCCGCAAGTTTC
TGCGAGTATAA

Upstream 100 bases:

>100_bases
ACACATAATAAAGAAATCGTAAACACCATGAAGAAACGTGTCATTGCAATCGAAGATGGTATCATTGTGCGTGATGAGTC
AAGAGGGGAGTATGGTTCAT

Downstream 100 bases:

>100_bases
AGTGAAAAAGCCGTTCCGTTTTCGGGACGGCTTTTCATTTGCCTTCTTTTTCTTCTATGATTACATGAAATCTCCATCCT
TTACATATACTATCTCTAGG

Product: cell-division ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIMLNLNNMATNAEKQVEIKVLIDLTADQKAQDKLQNDI
KELKGIQSVTFSSKEKELDQLVDSFGDSGKSLTMKDQENPLNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSR
LFKVVGVSRNIGIALIIGLVFTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWPFFLEGLLLGVFGSVIPIALVLS
TYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIAIGAVIGVWGSLTSIRKFLRV

Sequences:

>Translated_296_residues
MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIMLNLNNMATNAEKQVEIKVLIDLTADQKAQDKLQNDI
KELKGIQSVTFSSKEKELDQLVDSFGDSGKSLTMKDQENPLNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSR
LFKVVGVSRNIGIALIIGLVFTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWPFFLEGLLLGVFGSVIPIALVLS
TYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIAIGAVIGVWGSLTSIRKFLRV
>Mature_296_residues
MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIMLNLNNMATNAEKQVEIKVLIDLTADQKAQDKLQNDI
KELKGIQSVTFSSKEKELDQLVDSFGDSGKSLTMKDQENPLNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSR
LFKVVGVSRNIGIALIIGLVFTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWPFFLEGLLLGVFGSVIPIALVLS
TYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIAIGAVIGVWGSLTSIRKFLRV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily

Homologues:

Organism=Escherichia coli, GI1789872, Length=225, Percent_Identity=28.8888888888889, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSX_BACSU (O34876)

Other databases:

- EMBL:   AF017113
- EMBL:   AL009126
- PIR:   G69627
- RefSeq:   NP_391405.1
- EnsemblBacteria:   EBBACT00000002729
- GeneID:   936708
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU35250
- NMPDR:   fig|224308.1.peg.3531
- GenoList:   BSU35250
- GeneTree:   EBGT00050000000665
- HOGENOM:   HBG477103
- OMA:   IGSFFTC
- PhylomeDB:   O34876
- ProtClustDB:   CLSK887950
- BioCyc:   BSUB:BSU35250-MONOMER
- InterPro:   IPR003838

Pfam domain/function: PF02687 FtsX

EC number: NA

Molecular weight: Translated: 33100; Mature: 33100

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12b6688c)-; HASH(0x12b00af0)-; HASH(0xfee19cc)-; HASH(0x12068938)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIMLNLNNMATNAEKQVEI
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEE
KVLIDLTADQKAQDKLQNDIKELKGIQSVTFSSKEKELDQLVDSFGDSGKSLTMKDQENP
EEEEEECCCCHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
LNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSRLFKVVGVSRNIGIALIIGLV
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCHHHHHHHHH
FTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWPFFLEGLLLGVFGSVIPIALVLS
HHHHHHHCCCEEEEEEEECCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
TYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIAIGAVIGVWGSLTSIRKFLRV
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIMLNLNNMATNAEKQVEI
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEE
KVLIDLTADQKAQDKLQNDIKELKGIQSVTFSSKEKELDQLVDSFGDSGKSLTMKDQENP
EEEEEECCCCHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCCCC
LNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSRLFKVVGVSRNIGIALIIGLV
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCCCCCCHHHHHHHHH
FTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWPFFLEGLLLGVFGSVIPIALVLS
HHHHHHHCCCEEEEEEEECCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
TYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIAIGAVIGVWGSLTSIRKFLRV
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377