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The map label for this gene is trxB

Identifier: 16080532

GI number: 16080532

Start: 3573207

End: 3574157

Strand: Reverse

Name: trxB

Synonym: BSU34790

Alternate gene names: 16080532

Gene position: 3574157-3573207 (Counterclockwise)

Preceding gene: 16080533

Following gene: 16080531

Centisome position: 84.78

GC content: 44.16

Gene sequence:

>951_bases
GTGTCAGAAGAAAAAATTTATGACGTGATTATAATCGGCGCGGGCCCTGCTGGGATGACGGCCGCTGTATACACATCAAG
AGCGAATTTATCGACATTAATGATTGAAAGAGGAATTCCTGGCGGACAAATGGCCAATACGGAAGATGTAGAAAACTATC
CTGGATTCGAAAGTATCCTTGGGCCTGAGCTTTCTAACAAAATGTTTGAACACGCGAAAAAATTCGGCGCTGAATACGCT
TATGGCGATATTAAAGAGGTCATTGACGGCAAAGAGTACAAAGTAGTCAAAGCTGGTTCAAAGGAATATAAAGCCCGTGC
TGTCATCATTGCTGCAGGTGCGGAATATAAAAAAATCGGCGTGCCTGGCGAAAAAGAATTGGGCGGACGCGGTGTATCTT
ATTGTGCAGTATGTGACGGCGCTTTCTTTAAAGGCAAAGAACTTGTCGTTGTTGGCGGCGGAGATTCCGCGGTTGAAGAA
GGCGTATATCTGACTCGTTTCGCTTCAAAAGTAACGATTGTTCACAGACGTGATAAACTCCGTGCTCAAAGTATTCTTCA
AGCGAGAGCATTTGATAATGAAAAAGTTGACTTCCTATGGAACAAAACTGTGAAGGAAATTCATGAGGAAAACGGCAAAG
TCGGTAACGTAACGCTTGTCGATACGGTAACCGGTGAAGAAAGTGAATTCAAAACAGACGGCGTATTCATTTACATCGGC
ATGCTTCCTCTGTCTAAACCGTTTGAAAACCTGGGCATTACGAATGAAGAAGGCTATATCGAAACAAACGACCGCATGGA
AACTAAGGTTGAAGGGATTTTCGCTGCCGGAGACATCCGCGAAAAATCACTGCGCCAAATCGTAACGGCTACAGGAGACG
GAAGCATTGCGGCACAAAGCGTACAACATTATGTCGAAGAGCTCCAAGAAACGCTGAAAACCTTAAAATAA

Upstream 100 bases:

>100_bases
TGAGATTTTATAGGATATGGGTAAGGAATACGTTTGATGGGGATTCTTATCTTATAAGAAAGAGCCCAAACTTGAAAAGA
TGGTTTAAGGAGTGAATAGT

Downstream 100 bases:

>100_bases
AAAGGGCTGTCATACGAGTTTCACATTACGTTACTGGGTTTTAATTCCGCTGTAACACATGTGTAATGCTTTTCGGTTAT
GATTAATAAAGTAATTGACC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR; General stress protein 35; GSP35

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMIERGIPGGQMANTEDVENYPGFESILGPELSNKMFEHAKKFGAEYA
YGDIKEVIDGKEYKVVKAGSKEYKARAVIIAAGAEYKKIGVPGEKELGGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEE
GVYLTRFASKVTIVHRRDKLRAQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVTLVDTVTGEESEFKTDGVFIYIG
MLPLSKPFENLGITNEEGYIETNDRMETKVEGIFAAGDIREKSLRQIVTATGDGSIAAQSVQHYVEELQETLKTLK

Sequences:

>Translated_316_residues
MSEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMIERGIPGGQMANTEDVENYPGFESILGPELSNKMFEHAKKFGAEYA
YGDIKEVIDGKEYKVVKAGSKEYKARAVIIAAGAEYKKIGVPGEKELGGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEE
GVYLTRFASKVTIVHRRDKLRAQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVTLVDTVTGEESEFKTDGVFIYIG
MLPLSKPFENLGITNEEGYIETNDRMETKVEGIFAAGDIREKSLRQIVTATGDGSIAAQSVQHYVEELQETLKTLK
>Mature_315_residues
SEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMIERGIPGGQMANTEDVENYPGFESILGPELSNKMFEHAKKFGAEYAY
GDIKEVIDGKEYKVVKAGSKEYKARAVIIAAGAEYKKIGVPGEKELGGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEEG
VYLTRFASKVTIVHRRDKLRAQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVTLVDTVTGEESEFKTDGVFIYIGM
LPLSKPFENLGITNEEGYIETNDRMETKVEGIFAAGDIREKSLRQIVTATGDGSIAAQSVQHYVEELQETLKTLK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Homo sapiens, GI65787454, Length=327, Percent_Identity=23.8532110091743, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI226437568, Length=327, Percent_Identity=23.8532110091743, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI21389617, Length=327, Percent_Identity=23.8532110091743, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=38.006230529595, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI87081763, Length=311, Percent_Identity=33.7620578778135, Blast_Score=165, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=37.8980891719745, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6321898, Length=312, Percent_Identity=37.5, Blast_Score=189, Evalue=5e-49,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRXB_BACSU (P80880)

Other databases:

- EMBL:   Z94043
- EMBL:   AL009126
- PIR:   A69727
- RefSeq:   NP_391359.1
- ProteinModelPortal:   P80880
- SMR:   P80880
- EnsemblBacteria:   EBBACT00000000789
- GeneID:   936549
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU34790
- NMPDR:   fig|224308.1.peg.3485
- GenoList:   BSU34790
- GeneTree:   EBGT00050000000432
- HOGENOM:   HBG669726
- OMA:   RMETKIP
- PhylomeDB:   P80880
- ProtClustDB:   CLSK2752520
- BioCyc:   BSUB:BSU34790-MONOMER
- BRENDA:   1.8.1.9
- GO:   GO:0005737
- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR01292

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.8.1.9

Molecular weight: Translated: 34520; Mature: 34388

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMIERGIPGGQMANTEDVENYPGFESIL
CCCCEEEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHH
GPELSNKMFEHAKKFGAEYAYGDIKEVIDGKEYKVVKAGSKEYKARAVIIAAGAEYKKIG
CCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCEEECC
VPGEKELGGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEEGVYLTRFASKVTIVHRRDKL
CCCCHHCCCCCCEEEEEECCCEECCCEEEEECCCCHHHHCCEEEEEHHHHEEEEEHHHHH
RAQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVTLVDTVTGEESEFKTDGVFIYIG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCEEEEEE
MLPLSKPFENLGITNEEGYIETNDRMETKVEGIFAAGDIREKSLRQIVTATGDGSIAAQS
ECCCCCCHHHCCCCCCCCEEECCCCHHHHHHEEEEECCCCHHHHHHHHHCCCCCCHHHHH
VQHYVEELQETLKTLK
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEEKIYDVIIIGAGPAGMTAAVYTSRANLSTLMIERGIPGGQMANTEDVENYPGFESIL
CCCEEEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHH
GPELSNKMFEHAKKFGAEYAYGDIKEVIDGKEYKVVKAGSKEYKARAVIIAAGAEYKKIG
CCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCEEECC
VPGEKELGGRGVSYCAVCDGAFFKGKELVVVGGGDSAVEEGVYLTRFASKVTIVHRRDKL
CCCCHHCCCCCCEEEEEECCCEECCCEEEEECCCCHHHHCCEEEEEHHHHEEEEEHHHHH
RAQSILQARAFDNEKVDFLWNKTVKEIHEENGKVGNVTLVDTVTGEESEFKTDGVFIYIG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCEEEEEE
MLPLSKPFENLGITNEEGYIETNDRMETKVEGIFAAGDIREKSLRQIVTATGDGSIAAQS
ECCCCCCHHHCCCCCCCCEEECCCCHHHHHHEEEEECCCCHHHHHHHHHCCCCCCHHHHH
VQHYVEELQETLKTLK
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659