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The map label for this gene is yvcI

Identifier: 16080531

GI number: 16080531

Start: 3572413

End: 3572889

Strand: Reverse

Name: yvcI

Synonym: BSU34780

Alternate gene names: 16080531

Gene position: 3572889-3572413 (Counterclockwise)

Preceding gene: 16080532

Following gene: 16080530

Centisome position: 84.75

GC content: 46.12

Gene sequence:

>477_bases
GTGACGTACTTGCAAAGAGTGACAAATTGTGTGCTTCAGACGGATGACAAAGTTCTTCTGCTTCAAAAGCCGAGACGCGG
ATGGTGGGTCGCGCCGGGAGGCAAGATGGAGAGCGGAGAATCAGTCAGAGACTCCGTCATCAGAGAGTACAGAGAAGAGA
CTGGTATCTATATCATAAATCCTCAATTAAAAGGCGTTTTTACCTTTATTATTAAAGACGGTGACCACATTGTCTCCGAG
TGGATGATGTTTACGTTTGTCGCTGATTCATATACAGGACAAAATGTATCAGAATCAGAGGAAGGCAAACTGCAGTGGCA
CGATGTCAATGACATTCAGAACCTGCCTATGGCCCCTGGAGACGGCCATATCCTTGATTTTATGATGAAGGGACAAGGGC
TGCTGCACGGCACATTTACGTATACACCGGAATTTGAGCTGCTCAGTTATCGTTTAGACCCGCAGCACATCAAATAG

Upstream 100 bases:

>100_bases
AATATGCTGTAAAATAGAAGAAAAGATTGTCAATGTCTCTTCATTGTGGGAGGCATCTTGAAGCGGTATAATAAAGAGAC
GATGACAGGACGAAGGTTAG

Downstream 100 bases:

>100_bases
AAAGACAAGTCAGGGGGGAGAAAGATGAGTGTTAGTGAATCACATGATATTCAGCTTGTCATTATAACTGGAATGTCGGG
AGCGGGGAAAACTGTCGCGA

Product: triphosphate pyrophosphate hydrolase

Products: CMP; diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTYLQRVTNCVLQTDDKVLLLQKPRRGWWVAPGGKMESGESVRDSVIREYREETGIYIINPQLKGVFTFIIKDGDHIVSE
WMMFTFVADSYTGQNVSESEEGKLQWHDVNDIQNLPMAPGDGHILDFMMKGQGLLHGTFTYTPEFELLSYRLDPQHIK

Sequences:

>Translated_158_residues
MTYLQRVTNCVLQTDDKVLLLQKPRRGWWVAPGGKMESGESVRDSVIREYREETGIYIINPQLKGVFTFIIKDGDHIVSE
WMMFTFVADSYTGQNVSESEEGKLQWHDVNDIQNLPMAPGDGHILDFMMKGQGLLHGTFTYTPEFELLSYRLDPQHIK
>Mature_157_residues
TYLQRVTNCVLQTDDKVLLLQKPRRGWWVAPGGKMESGESVRDSVIREYREETGIYIINPQLKGVFTFIIKDGDHIVSEW
MMFTFVADSYTGQNVSESEEGKLQWHDVNDIQNLPMAPGDGHILDFMMKGQGLLHGTFTYTPEFELLSYRLDPQHIK

Specific function: Specific For Pyrimidine Substrates. Acts On 5-Methyl- Dctp, Ctp And Dctp In Decreasing Order. [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YVCI_BACSU (O06972)

Other databases:

- EMBL:   Z94043
- EMBL:   AL009126
- PIR:   G70031
- RefSeq:   NP_391358.1
- HSSP:   Q82XR9
- ProteinModelPortal:   O06972
- SMR:   O06972
- EnsemblBacteria:   EBBACT00000002215
- GeneID:   936528
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU34780
- NMPDR:   fig|224308.1.peg.3484
- GenoList:   BSU34780
- GeneTree:   EBGT00050000000485
- HOGENOM:   HBG404367
- OMA:   GWWVAPG
- ProtClustDB:   CLSK873648
- BioCyc:   BSUB:BSU34780-MONOMER
- InterPro:   IPR020476
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 18214; Mature: 18083

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLQRVTNCVLQTDDKVLLLQKPRRGWWVAPGGKMESGESVRDSVIREYREETGIYIIN
CCHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
PQLKGVFTFIIKDGDHIVSEWMMFTFVADSYTGQNVSESEEGKLQWHDVNDIQNLPMAPG
CCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
DGHILDFMMKGQGLLHGTFTYTPEFELLSYRLDPQHIK
CCCEEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TYLQRVTNCVLQTDDKVLLLQKPRRGWWVAPGGKMESGESVRDSVIREYREETGIYIIN
CHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
PQLKGVFTFIIKDGDHIVSEWMMFTFVADSYTGQNVSESEEGKLQWHDVNDIQNLPMAPG
CCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
DGHILDFMMKGQGLLHGTFTYTPEFELLSYRLDPQHIK
CCCEEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; H2O [C]

Specific reaction: CTP + H2O = CMP + diphosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377