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The map label for this gene is yvcN

Identifier: 16080526

GI number: 16080526

Start: 3568527

End: 3569291

Strand: Reverse

Name: yvcN

Synonym: BSU34730

Alternate gene names: 16080526

Gene position: 3569291-3568527 (Counterclockwise)

Preceding gene: 16080527

Following gene: 16080525

Centisome position: 84.67

GC content: 46.01

Gene sequence:

>765_bases
GTGATAAAAATGAGTGACTTTCTAAAAGACTGCTTTCAGAAAATCGGCTGGGAGAAAGACCATGTCAGCTTCGGCGATCT
TCCCCTTTTTCTTAAAGCAATGGCATACCGTTTTCCATTCGAAAACCGTGCCGTACTTGCAAAAGAGAATTATAAGATCA
CAAAAGAAGAGCTATGGCGACGTCTGCTCAAAGATCAGCACGGCGGCCTATGCTACGATCTAAATGGTTTCCTTTATTTT
GTCTTGCGTGAGGCCGGGTTTCATGTGAAGCTCATTCGAGGAACGGTTTATGCAGGCGATCAAGAGGGATGGGCACTAGA
AGGGACGCATGCTGCTGTATGGCTGTCTGCGGAAAACGGCGATTACCTCGTTGATATCGGCTTCGGCATCAACCTGGCGC
TCCAGCCGATACCGCTTTCCGGAGAAACGGTACAGTCACCAGTCGGGTCATTCCGAATCAAAAAGGAAGAGACAGAAAAG
GGCAGCTATGTTCTGCTGATGGACAAAGGAGAAGGCTGGCAAATTGGGTACGCCTTTACCCTTGAAGAGAGTGATCTCGG
TGATTTAGATAACATGAAGGACATCATTCACTCTCATGAAAAATCTCCTTTTAACAAATCCCTGCTTGCCTCAAAGCTGA
CGCCGAGCGGAAGGATGGTCATGTCAGAGCGCCATTTTACGATTTATGAAAACGGCGGTAACATTCAAAAAAGCGACATC
GGCCCTTCAGGATTTGAAGAGAAATTAAATACTCATTTTTTGTAA

Upstream 100 bases:

>100_bases
TGCGGTAAGCACAGGCACTGAGGTTACCTTGATTGCCCAGGGAGAAGATGAACAAGAGGCGCTGGAGAAGCTGGCTGCTT
ACGTTCAAGAAGAAGTTTAG

Downstream 100 bases:

>100_bases
CGTGAAAAGCTTGCAGGTTATCTGCAAGCTTTTTCTTATGAACAAGTGTAGATTGCTGTATCAAATGCGTCTTCTGGGAT
ATACAGTTTTCCCTTTTCGT

Product: acetyltransferase

Products: CoA; an n-acetoxyarylamine [C]

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MIKMSDFLKDCFQKIGWEKDHVSFGDLPLFLKAMAYRFPFENRAVLAKENYKITKEELWRRLLKDQHGGLCYDLNGFLYF
VLREAGFHVKLIRGTVYAGDQEGWALEGTHAAVWLSAENGDYLVDIGFGINLALQPIPLSGETVQSPVGSFRIKKEETEK
GSYVLLMDKGEGWQIGYAFTLEESDLGDLDNMKDIIHSHEKSPFNKSLLASKLTPSGRMVMSERHFTIYENGGNIQKSDI
GPSGFEEKLNTHFL

Sequences:

>Translated_254_residues
MIKMSDFLKDCFQKIGWEKDHVSFGDLPLFLKAMAYRFPFENRAVLAKENYKITKEELWRRLLKDQHGGLCYDLNGFLYF
VLREAGFHVKLIRGTVYAGDQEGWALEGTHAAVWLSAENGDYLVDIGFGINLALQPIPLSGETVQSPVGSFRIKKEETEK
GSYVLLMDKGEGWQIGYAFTLEESDLGDLDNMKDIIHSHEKSPFNKSLLASKLTPSGRMVMSERHFTIYENGGNIQKSDI
GPSGFEEKLNTHFL
>Mature_254_residues
MIKMSDFLKDCFQKIGWEKDHVSFGDLPLFLKAMAYRFPFENRAVLAKENYKITKEELWRRLLKDQHGGLCYDLNGFLYF
VLREAGFHVKLIRGTVYAGDQEGWALEGTHAAVWLSAENGDYLVDIGFGINLALQPIPLSGETVQSPVGSFRIKKEETEK
GSYVLLMDKGEGWQIGYAFTLEESDLGDLDNMKDIIHSHEKSPFNKSLLASKLTPSGRMVMSERHFTIYENGGNIQKSDI
GPSGFEEKLNTHFL

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family

Homologues:

Organism=Homo sapiens, GI237649132, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI237649130, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI237649128, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI237649126, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI237649124, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI237649122, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI237649119, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI42741671, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI237649009, Length=267, Percent_Identity=22.4719101123595, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787736, Length=241, Percent_Identity=28.2157676348548, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YVCN_BACSU (O06977)

Other databases:

- EMBL:   Z94043
- EMBL:   AL009126
- PIR:   C70032
- RefSeq:   NP_391353.1
- ProteinModelPortal:   O06977
- SMR:   O06977
- EnsemblBacteria:   EBBACT00000002039
- GeneID:   936525
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU34730
- NMPDR:   fig|224308.1.peg.3479
- GenoList:   BSU34730
- GeneTree:   EBGT00050000003040
- HOGENOM:   HBG339291
- OMA:   YLIEVGF
- PhylomeDB:   O06977
- ProtClustDB:   CLSK2752519
- BioCyc:   BSUB:BSU34730-MONOMER
- InterPro:   IPR001447
- PANTHER:   PTHR11786
- PRINTS:   PR01543

Pfam domain/function: PF00797 Acetyltransf_2

EC number: 2.3.1.118 [C]

Molecular weight: Translated: 28826; Mature: 28826

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: ACT_SITE 71-71 ACT_SITE 110-110 ACT_SITE 125-125

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKMSDFLKDCFQKIGWEKDHVSFGDLPLFLKAMAYRFPFENRAVLAKENYKITKEELWR
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCEECHHHHHH
RLLKDQHGGLCYDLNGFLYFVLREAGFHVKLIRGTVYAGDQEGWALEGTHAAVWLSAENG
HHHHCCCCCEEEECCHHEEEEEHHCCCEEEEEEEEEEECCCCCCEEECCEEEEEEEECCC
DYLVDIGFGINLALQPIPLSGETVQSPVGSFRIKKEETEKGSYVLLMDKGEGWQIGYAFT
CEEEEECCCCEEEEEECCCCCCHHHCCCCCEEEECCCCCCCCEEEEEECCCCEEEEEEEE
LEESDLGDLDNMKDIIHSHEKSPFNKSLLASKLTPSGRMVMSERHFTIYENGGNIQKSDI
ECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEECCCEEEEECCCCEEECCC
GPSGFEEKLNTHFL
CCCCHHHHHHHCCC
>Mature Secondary Structure
MIKMSDFLKDCFQKIGWEKDHVSFGDLPLFLKAMAYRFPFENRAVLAKENYKITKEELWR
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCEECHHHHHH
RLLKDQHGGLCYDLNGFLYFVLREAGFHVKLIRGTVYAGDQEGWALEGTHAAVWLSAENG
HHHHCCCCCEEEECCHHEEEEEHHCCCEEEEEEEEEEECCCCCCEEECCEEEEEEEECCC
DYLVDIGFGINLALQPIPLSGETVQSPVGSFRIKKEETEKGSYVLLMDKGEGWQIGYAFT
CEEEEECCCCEEEEEECCCCCCHHHCCCCCEEEECCCCCCCCEEEEEECCCCEEEEEEEE
LEESDLGDLDNMKDIIHSHEKSPFNKSLLASKLTPSGRMVMSERHFTIYENGGNIQKSDI
ECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEECCCEEEEECCCCEEECCC
GPSGFEEKLNTHFL
CCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; an n-hydroxyarylamine [C]

Specific reaction: Acetyl-CoA + an n-hydroxyarylamine = CoA + an n-acetoxyarylamine [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377