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The map label for this gene is ganR

Identifier: 16080470

GI number: 16080470

Start: 3508659

End: 3509651

Strand: Reverse

Name: ganR

Synonym: BSU34170

Alternate gene names: 16080470

Gene position: 3509651-3508659 (Counterclockwise)

Preceding gene: 255767768

Following gene: 16080469

Centisome position: 83.25

GC content: 43.4

Gene sequence:

>993_bases
ATGGCGACAATTAAAGATATCGCGCAGGAAGCGGGATTTTCAATCTCAACCGTTTCCCGCGTTTTAAATAACGATGAAAG
CCTTTCTGTTCCTGATGAGACACGGGAGAAAATCTATGAAGCGGCGGAAAAGCTCAATTACCGCAAAAAAACAGTAAGGC
CGCTGGTGAAACATATTGCGTTTTTATATTGGCTGACAGATAAAGAAGAATTAGAAGATGTCTATTTTAAAACGATGAGA
TTAGAAGTAGAGAAACTGGCGAAAGCATTCAATGTCGATATGACCACTTATAAAATAGCGGATGGAATCGAGAGCATTCC
TGAACATACGGAAGGGTTTATTGCCGTCGGCACATTTTCAGATGAAGAGCTGGCTTTCCTCAGAAATCTCACTGAAAACG
GCGTGTTCATCGATTCAACTCCTGATCCCGATCATTTTGACTCGGTAAGGCCCGATTTGGCACAAATGACAAGGAAGACG
GTAAACATCCTGACTGAGAAGGGGCATAAGAGCATCGGTTTTATCGGCGGCACATACAAAAATCCGAATACCAATCAGGA
TGAAATGGACATCCGTGAACAAACCTTCAGATCCTATATGAGGGAAAAAGCCATGCTGGACGAGCGCTATATTTTCTGTC
ATCGCGGATTCTCTGTAGAAAACGGCTACCGCCTGATGTCAGCAGCGATCGACACATTAGGCGATCAGCTTCCGACTGCT
TTTATGATTGCAGCGGACCCGATTGCAGTGGGCTGTCTGCAAGCCCTGAACGAAAAAGGAATTGCCATACCAAACAGGGT
AAGCATTGTGAGTATCAACAACATCAGCTTCGCGAAGTATGTCTCGCCTCCTCTGACGACGTTTCATATTGATATACATG
AATTATGTAAAAACGCTGTTCAATTACTGCTTGAACAAGTGCAGGACAAGAGAAGAACGGTAAAAACATTATATGTGGGC
GCAGAATTAATCGTCAGGAAGAGTATGAATTAA

Upstream 100 bases:

>100_bases
TTACATGGCAGCCAGAGGGCTTTGTGCACTTGACATTTGTGAAAAAGAAAGTAAAATATTTTACTAAAACAATGCGAGCT
GAATAATGGAGGCAGATACA

Downstream 100 bases:

>100_bases
GGATGACTTAGGACACTAAGTCATTTTTTATTTAGGTAAAAAAATTTACTCTATGAAGTAAATAGTTTGTTTACACATTT
TCTCAGGCATGCTATATTAT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MATIKDIAQEAGFSISTVSRVLNNDESLSVPDETREKIYEAAEKLNYRKKTVRPLVKHIAFLYWLTDKEELEDVYFKTMR
LEVEKLAKAFNVDMTTYKIADGIESIPEHTEGFIAVGTFSDEELAFLRNLTENGVFIDSTPDPDHFDSVRPDLAQMTRKT
VNILTEKGHKSIGFIGGTYKNPNTNQDEMDIREQTFRSYMREKAMLDERYIFCHRGFSVENGYRLMSAAIDTLGDQLPTA
FMIAADPIAVGCLQALNEKGIAIPNRVSIVSINNISFAKYVSPPLTTFHIDIHELCKNAVQLLLEQVQDKRRTVKTLYVG
AELIVRKSMN

Sequences:

>Translated_330_residues
MATIKDIAQEAGFSISTVSRVLNNDESLSVPDETREKIYEAAEKLNYRKKTVRPLVKHIAFLYWLTDKEELEDVYFKTMR
LEVEKLAKAFNVDMTTYKIADGIESIPEHTEGFIAVGTFSDEELAFLRNLTENGVFIDSTPDPDHFDSVRPDLAQMTRKT
VNILTEKGHKSIGFIGGTYKNPNTNQDEMDIREQTFRSYMREKAMLDERYIFCHRGFSVENGYRLMSAAIDTLGDQLPTA
FMIAADPIAVGCLQALNEKGIAIPNRVSIVSINNISFAKYVSPPLTTFHIDIHELCKNAVQLLLEQVQDKRRTVKTLYVG
AELIVRKSMN
>Mature_329_residues
ATIKDIAQEAGFSISTVSRVLNNDESLSVPDETREKIYEAAEKLNYRKKTVRPLVKHIAFLYWLTDKEELEDVYFKTMRL
EVEKLAKAFNVDMTTYKIADGIESIPEHTEGFIAVGTFSDEELAFLRNLTENGVFIDSTPDPDHFDSVRPDLAQMTRKTV
NILTEKGHKSIGFIGGTYKNPNTNQDEMDIREQTFRSYMREKAMLDERYIFCHRGFSVENGYRLMSAAIDTLGDQLPTAF
MIAADPIAVGCLQALNEKGIAIPNRVSIVSINNISFAKYVSPPLTTFHIDIHELCKNAVQLLLEQVQDKRRTVKTLYVGA
ELIVRKSMN

Specific function: Negatively regulates expression of ganA

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789456, Length=334, Percent_Identity=33.5329341317365, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787948, Length=351, Percent_Identity=28.4900284900285, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790369, Length=339, Percent_Identity=27.7286135693215, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788474, Length=330, Percent_Identity=28.1818181818182, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789068, Length=319, Percent_Identity=22.5705329153605, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GANR_BACSU (O07008)

Other databases:

- EMBL:   Z94043
- EMBL:   AL009126
- PIR:   C69649
- RefSeq:   NP_391297.1
- HSSP:   P03023
- ProteinModelPortal:   O07008
- SMR:   O07008
- EnsemblBacteria:   EBBACT00000003682
- GeneID:   936331
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU34170
- NMPDR:   fig|224308.1.peg.3423
- GenoList:   BSU34170
- GeneTree:   EBGT00070000032245
- HOGENOM:   HBG753640
- OMA:   ELEDVYF
- PhylomeDB:   O07008
- ProtClustDB:   CLSK873198
- BioCyc:   BSUB:BSU34170-MONOMER
- GO:   GO:0005622
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- SMART:   SM00354

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1; SSF47413 Lambda_like_DNA

EC number: NA

Molecular weight: Translated: 37462; Mature: 37331

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00356 HTH_LACI_1; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIKDIAQEAGFSISTVSRVLNNDESLSVPDETREKIYEAAEKLNYRKKTVRPLVKHIA
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLYWLTDKEELEDVYFKTMRLEVEKLAKAFNVDMTTYKIADGIESIPEHTEGFIAVGTFS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
DEELAFLRNLTENGVFIDSTPDPDHFDSVRPDLAQMTRKTVNILTEKGHKSIGFIGGTYK
CHHHHHHHHHCCCCEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
NPNTNQDEMDIREQTFRSYMREKAMLDERYIFCHRGFSVENGYRLMSAAIDTLGDQLPTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHCCCE
FMIAADPIAVGCLQALNEKGIAIPNRVSIVSINNISFAKYVSPPLTTFHIDIHELCKNAV
EEEECCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHCCCCCEEEEEEHHHHHHHHH
QLLLEQVQDKRRTVKTLYVGAELIVRKSMN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATIKDIAQEAGFSISTVSRVLNNDESLSVPDETREKIYEAAEKLNYRKKTVRPLVKHIA
CCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLYWLTDKEELEDVYFKTMRLEVEKLAKAFNVDMTTYKIADGIESIPEHTEGFIAVGTFS
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCC
DEELAFLRNLTENGVFIDSTPDPDHFDSVRPDLAQMTRKTVNILTEKGHKSIGFIGGTYK
CHHHHHHHHHCCCCEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
NPNTNQDEMDIREQTFRSYMREKAMLDERYIFCHRGFSVENGYRLMSAAIDTLGDQLPTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHCCCE
FMIAADPIAVGCLQALNEKGIAIPNRVSIVSINNISFAKYVSPPLTTFHIDIHELCKNAV
EEEECCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHCCCCCEEEEEEHHHHHHHHH
QLLLEQVQDKRRTVKTLYVGAELIVRKSMN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377