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The map label for this gene is fhuG

Identifier: 16080384

GI number: 16080384

Start: 3416212

End: 3417222

Strand: Reverse

Name: fhuG

Synonym: BSU33300

Alternate gene names: 16080384

Gene position: 3417222-3416212 (Counterclockwise)

Preceding gene: 16080385

Following gene: 16080383

Centisome position: 81.06

GC content: 48.07

Gene sequence:

>1011_bases
ATGAAAACAAAAACAAACAAACCGCTCATTGTAATGGCTGTGACCTTTTTGCTTATCGTGGTGGTCTTTTTTATCAGTCT
CAATTTGGGCGTTATCAAAATTGCACCGCTTAAAACGCTTCAGGTCTTTTTCGGCCAAGGAACGGCGCGTGATGAACTTG
TCTTATTTGAGTTCAGGCTGCCCCGGATCATCCTTTCTTTGCTTGTTGGAGCAGGGATCTCCGTAGCTGGAGCCATTTTG
CAAAGCGTGTCTCAAAATGAACTTGCCGAGCCTGGTATTCTCGGAATTAACGCCGGCGGTTCACTTGCTGTAGTGCTTTT
TATATACTTTTTTCAAGGGTCAGCTTCAGATCTTAGCTTTTTCGGAACATTTATGCTGCCGTTCAGTGCTTTGGCAGGAG
CAATCCTCGCTGCGTTTCTCATTTATATTCTGGCATGGAAAAAAGGCGTGACACCGATTCGGCTGATTTTAGTCGGCATA
GGGGTGAATGCCGGATTCAACGCCCTGTTGCTGATTTTTCAGCTCAAGATGGACCCTCATGATTTTATGCAAGCCGCGGT
TTGGATATCCGGCTCAATATGGGGGGCGAACTGGAATATGATCTGGGCGATTCTCCCTTGGATTGTGATCTTGCTTCTGT
TTACTTTATATAAGGCACGCTATTTGAACATTATGCAGCTCGGAGACCAATTGGCGACCGGGCTGGGCACCGCTGTTGAA
AAGGAAAGACGGATTCTTCTTCTGGCAGCGGTCACTCTTGCCGCTTCATGCGTGGCAGCTGCGGGGGGCATTGCGTTTCT
CGGATTGATCGCGCCGCATGTGGCTAGAAGGCTGACCGGTCCACGTCACCAGACGCTGATACCGGTCTCCGCCTTCATCG
GCTCATTCCTGTTTTTGCTTGCTGATACGCTGGCGAGAAATGTATTGGCACCATCAGAAATTCCGGTCGGACTTGTCATT
TCCGTGCTAGGTGCGCCTTACTTTATTTATTTATTGATGAAAGCGAATTAG

Upstream 100 bases:

>100_bases
TCGTAAATGCGCCCTTTGAAACGCCTGTCGGCGCGCTGACTTCTCTTATCGGCGTTCCCTTTTTCTTTTATTTGGCACGT
CGTGAAAGGAGAGGGCTGTA

Downstream 100 bases:

>100_bases
AGGAGGGGGCCGAATATGAATTCATTATCAACGGAACAGCTTGGAATCGGTTATGGCGACAGGGTGATTGTAGAGGATTT
AAATATATCGATTCCTAAAG

Product: ferrichrome ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKTKTNKPLIVMAVTFLLIVVVFFISLNLGVIKIAPLKTLQVFFGQGTARDELVLFEFRLPRIILSLLVGAGISVAGAIL
QSVSQNELAEPGILGINAGGSLAVVLFIYFFQGSASDLSFFGTFMLPFSALAGAILAAFLIYILAWKKGVTPIRLILVGI
GVNAGFNALLLIFQLKMDPHDFMQAAVWISGSIWGANWNMIWAILPWIVILLLFTLYKARYLNIMQLGDQLATGLGTAVE
KERRILLLAAVTLAASCVAAAGGIAFLGLIAPHVARRLTGPRHQTLIPVSAFIGSFLFLLADTLARNVLAPSEIPVGLVI
SVLGAPYFIYLLMKAN

Sequences:

>Translated_336_residues
MKTKTNKPLIVMAVTFLLIVVVFFISLNLGVIKIAPLKTLQVFFGQGTARDELVLFEFRLPRIILSLLVGAGISVAGAIL
QSVSQNELAEPGILGINAGGSLAVVLFIYFFQGSASDLSFFGTFMLPFSALAGAILAAFLIYILAWKKGVTPIRLILVGI
GVNAGFNALLLIFQLKMDPHDFMQAAVWISGSIWGANWNMIWAILPWIVILLLFTLYKARYLNIMQLGDQLATGLGTAVE
KERRILLLAAVTLAASCVAAAGGIAFLGLIAPHVARRLTGPRHQTLIPVSAFIGSFLFLLADTLARNVLAPSEIPVGLVI
SVLGAPYFIYLLMKAN
>Mature_336_residues
MKTKTNKPLIVMAVTFLLIVVVFFISLNLGVIKIAPLKTLQVFFGQGTARDELVLFEFRLPRIILSLLVGAGISVAGAIL
QSVSQNELAEPGILGINAGGSLAVVLFIYFFQGSASDLSFFGTFMLPFSALAGAILAAFLIYILAWKKGVTPIRLILVGI
GVNAGFNALLLIFQLKMDPHDFMQAAVWISGSIWGANWNMIWAILPWIVILLLFTLYKARYLNIMQLGDQLATGLGTAVE
KERRILLLAAVTLAASCVAAAGGIAFLGLIAPHVARRLTGPRHQTLIPVSAFIGSFLFLLADTLARNVLAPSEIPVGLVI
SVLGAPYFIYLLMKAN

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily

Homologues:

Organism=Escherichia coli, GI1790740, Length=311, Percent_Identity=37.9421221864952, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1786347, Length=282, Percent_Identity=38.2978723404255, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786804, Length=306, Percent_Identity=35.2941176470588, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=33.5640138408304, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1790741, Length=336, Percent_Identity=29.4642857142857, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786805, Length=311, Percent_Identity=33.4405144694534, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FHUG_BACSU (P49937)

Other databases:

- EMBL:   X93092
- EMBL:   AJ223978
- EMBL:   AL009126
- PIR:   D69622
- RefSeq:   NP_391211.1
- ProteinModelPortal:   P49937
- SMR:   P49937
- EnsemblBacteria:   EBBACT00000000210
- GeneID:   938619
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33300
- NMPDR:   fig|224308.1.peg.3337
- GenoList:   BSU33300
- GeneTree:   EBGT00070000031767
- HOGENOM:   HBG700016
- OMA:   VWISGSI
- PhylomeDB:   P49937
- ProtClustDB:   CLSK2391284
- BioCyc:   BSUB:BSU33300-MONOMER
- InterPro:   IPR000522

Pfam domain/function: PF01032 FecCD

EC number: NA

Molecular weight: Translated: 36155; Mature: 36155

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x109ae260)-; HASH(0x12254eb8)-; HASH(0x11067148)-; HASH(0x123978a8)-; HASH(0x126752e8)-; HASH(0x1235f4d4)-; HASH(0x11f103dc)-; HASH(0x1260b468)-; HASH(0x121fe44c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKTNKPLIVMAVTFLLIVVVFFISLNLGVIKIAPLKTLQVFFGQGTARDELVLFEFRL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCCCEEEEEHHH
PRIILSLLVGAGISVAGAILQSVSQNELAEPGILGINAGGSLAVVLFIYFFQGSASDLSF
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHH
FGTFMLPFSALAGAILAAFLIYILAWKKGVTPIRLILVGIGVNAGFNALLLIFQLKMDPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEEEECCCCCCHHHHHHHHHHCCCHH
DFMQAAVWISGSIWGANWNMIWAILPWIVILLLFTLYKARYLNIMQLGDQLATGLGTAVE
HHHHHHHHEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KERRILLLAAVTLAASCVAAAGGIAFLGLIAPHVARRLTGPRHQTLIPVSAFIGSFLFLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHH
ADTLARNVLAPSEIPVGLVISVLGAPYFIYLLMKAN
HHHHHHHCCCCCCCCHHHHHHHHCCHHEEEEEEECH
>Mature Secondary Structure
MKTKTNKPLIVMAVTFLLIVVVFFISLNLGVIKIAPLKTLQVFFGQGTARDELVLFEFRL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCCCEEEEEHHH
PRIILSLLVGAGISVAGAILQSVSQNELAEPGILGINAGGSLAVVLFIYFFQGSASDLSF
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHH
FGTFMLPFSALAGAILAAFLIYILAWKKGVTPIRLILVGIGVNAGFNALLLIFQLKMDPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEEEECCCCCCHHHHHHHHHHCCCHH
DFMQAAVWISGSIWGANWNMIWAILPWIVILLLFTLYKARYLNIMQLGDQLATGLGTAVE
HHHHHHHHEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KERRILLLAAVTLAASCVAAAGGIAFLGLIAPHVARRLTGPRHQTLIPVSAFIGSFLFLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHH
ADTLARNVLAPSEIPVGLVISVLGAPYFIYLLMKAN
HHHHHHHCCCCCCCCHHHHHHHHCCHHEEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377