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The map label for this gene is yvrB

Identifier: 16080370

GI number: 16080370

Start: 3402469

End: 3403530

Strand: Reverse

Name: yvrB

Synonym: BSU33170

Alternate gene names: 16080370

Gene position: 3403530-3402469 (Counterclockwise)

Preceding gene: 16080371

Following gene: 16080369

Centisome position: 80.74

GC content: 48.68

Gene sequence:

>1062_bases
TTGCGGAAAGCATTTACCCGGATACGTTTAAGGAATAATCGTTATGCCGCATATATCATTGGTTTCTCATTTTTAGCCGT
GAGCATCATCTTAGGAATTTCTTGCGGCAGCCTGCATATTCCTATTCCCGCTGTTTTTCGTGTCTTTTGGCATCAAGGTT
TCGGCGGCTCTATCGGTTCTGATGATCCGATGTACACTAATATTATGATGAATATCAGACTGCCGAGAGTTGTGCTGGCC
GCCCTTGTGGGGGCGGCTCTTTCTATTGCAGGGGCCGCTTTTCAAGGATTGTTGAAAAATCCGCTTGCTGATCCCTATAC
GCTAGGTGTGTCATCCGGTGCTTCAGTCGGAGCTGTTGTGACTCTGTTCTTAGGTTTGCACCTTCCTGTCATCGGAGGGT
TTACACTCCCGGTTTTGAGTGTAGCCGCGGCACTGGCCACGATGGCGGCGGTCCTTTTCTTCAGCCGCCTCGTTCATGCT
TCGATGTCTGTTTCCACCCTCATTTTGACCGGTGTCATCACCAACTCTTTTTTAGGCGCATTTATTTCTCTTATCATCGC
CTTGACAGGAGACAACCTGCTTCCGATTGTGCATTGGCTGCTTGGCAGCGTCTCAATGAGGGGCTGGAGCTATGTTATTT
TGTTTCTCCCGTTTTTTCTTTTGGGAACCATTTTATTGATTATAAACGGAAGGGAACTGAACGTGATGACATATGGAGAA
GATAAAGCAAAGCTTCTTGGAGTCAGCGTTCAGCAGAGGAAGATGATGATTTTAATAGCCGGATCTCTTTTGACGGGAAG
CGCTGTGGCAGTATCGGGTACGATTGGCTTTGTCGGCCTTGTGATTCCGCATATCACAAGGCTTTTGTGGGGAACGGACC
ATCGGCATTTACTGCCGTTGTCCGCCTTGCTTGGGGCAGGGTTTCTTGTTTTAGCCGATCTGCTTTCCAGAACCATCATT
GAGCCGATTGAACTGCCGATCGGGATCATTACGTCCTTGGCGGGAGCGCCTGTGTTCGCTCTTATTTTAATTCGGCAGCA
TCGCGGGGGGAGAAGCTTATGA

Upstream 100 bases:

>100_bases
TGGAGCGAAATCAATGCTGTGAAACATCATCGTGTATATGATGTGGACCCTGATCTTGTGACACGTTCCGGTCCCCGTCT
GATCGAAGGGGTCGAAGAAC

Downstream 100 bases:

>100_bases
TGAAGGCAGAAGGGCTGTCGGGAGGATACGGCGACAGCCGCCTAATCAACAATGTCAGCTTAACAGTGGAGAAGGGAGAA
TTTCTTGGAATTCTCGGCCC

Product: vitamin B12 permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MRKAFTRIRLRNNRYAAYIIGFSFLAVSIILGISCGSLHIPIPAVFRVFWHQGFGGSIGSDDPMYTNIMMNIRLPRVVLA
ALVGAALSIAGAAFQGLLKNPLADPYTLGVSSGASVGAVVTLFLGLHLPVIGGFTLPVLSVAAALATMAAVLFFSRLVHA
SMSVSTLILTGVITNSFLGAFISLIIALTGDNLLPIVHWLLGSVSMRGWSYVILFLPFFLLGTILLIINGRELNVMTYGE
DKAKLLGVSVQQRKMMILIAGSLLTGSAVAVSGTIGFVGLVIPHITRLLWGTDHRHLLPLSALLGAGFLVLADLLSRTII
EPIELPIGIITSLAGAPVFALILIRQHRGGRSL

Sequences:

>Translated_353_residues
MRKAFTRIRLRNNRYAAYIIGFSFLAVSIILGISCGSLHIPIPAVFRVFWHQGFGGSIGSDDPMYTNIMMNIRLPRVVLA
ALVGAALSIAGAAFQGLLKNPLADPYTLGVSSGASVGAVVTLFLGLHLPVIGGFTLPVLSVAAALATMAAVLFFSRLVHA
SMSVSTLILTGVITNSFLGAFISLIIALTGDNLLPIVHWLLGSVSMRGWSYVILFLPFFLLGTILLIINGRELNVMTYGE
DKAKLLGVSVQQRKMMILIAGSLLTGSAVAVSGTIGFVGLVIPHITRLLWGTDHRHLLPLSALLGAGFLVLADLLSRTII
EPIELPIGIITSLAGAPVFALILIRQHRGGRSL
>Mature_353_residues
MRKAFTRIRLRNNRYAAYIIGFSFLAVSIILGISCGSLHIPIPAVFRVFWHQGFGGSIGSDDPMYTNIMMNIRLPRVVLA
ALVGAALSIAGAAFQGLLKNPLADPYTLGVSSGASVGAVVTLFLGLHLPVIGGFTLPVLSVAAALATMAAVLFFSRLVHA
SMSVSTLILTGVITNSFLGAFISLIIALTGDNLLPIVHWLLGSVSMRGWSYVILFLPFFLLGTILLIINGRELNVMTYGE
DKAKLLGVSVQQRKMMILIAGSLLTGSAVAVSGTIGFVGLVIPHITRLLWGTDHRHLLPLSALLGAGFLVLADLLSRTII
EPIELPIGIITSLAGAPVFALILIRQHRGGRSL

Specific function: Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily

Homologues:

Organism=Escherichia coli, GI1790740, Length=322, Percent_Identity=36.3354037267081, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1788004, Length=282, Percent_Identity=39.3617021276596, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790741, Length=322, Percent_Identity=31.055900621118, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1786805, Length=306, Percent_Identity=33.9869281045752, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786347, Length=292, Percent_Identity=29.1095890410959, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786804, Length=300, Percent_Identity=31, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YVRB_BACSU (O34451)

Other databases:

- EMBL:   AJ223978
- EMBL:   AL009126
- PIR:   F70046
- RefSeq:   NP_391197.1
- HSSP:   P06609
- ProteinModelPortal:   O34451
- SMR:   O34451
- EnsemblBacteria:   EBBACT00000002963
- GeneID:   938583
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33170
- NMPDR:   fig|224308.1.peg.3323
- GenoList:   BSU33170
- GeneTree:   EBGT00070000031853
- HOGENOM:   HBG700016
- OMA:   PRIIMAI
- PhylomeDB:   O34451
- ProtClustDB:   CLSK873072
- BioCyc:   BSUB:BSU33170-MONOMER
- InterPro:   IPR000522

Pfam domain/function: PF01032 FecCD

EC number: NA

Molecular weight: Translated: 37498; Mature: 37498

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x117c1424)-; HASH(0x124e9c2c)-; HASH(0x123f4bb8)-; HASH(0x1208b2f0)-; HASH(0x123ec0b4)-; HASH(0x1231dc60)-; HASH(0x12602328)-; HASH(0x112ed160)-; HASH(0x123f4eb4)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAFTRIRLRNNRYAAYIIGFSFLAVSIILGISCGSLHIPIPAVFRVFWHQGFGGSIGS
CCCHHHHHEEECCCEEEEHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCCCC
DDPMYTNIMMNIRLPRVVLAALVGAALSIAGAAFQGLLKNPLADPYTLGVSSGASVGAVV
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
TLFLGLHLPVIGGFTLPVLSVAAALATMAAVLFFSRLVHASMSVSTLILTGVITNSFLGA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FISLIIALTGDNLLPIVHWLLGSVSMRGWSYVILFLPFFLLGTILLIINGRELNVMTYGE
HHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECC
DKAKLLGVSVQQRKMMILIAGSLLTGSAVAVSGTIGFVGLVIPHITRLLWGTDHRHLLPL
CCHHHCCCCHHHCEEEEEEECCHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHH
SALLGAGFLVLADLLSRTIIEPIELPIGIITSLAGAPVFALILIRQHRGGRSL
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MRKAFTRIRLRNNRYAAYIIGFSFLAVSIILGISCGSLHIPIPAVFRVFWHQGFGGSIGS
CCCHHHHHEEECCCEEEEHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCCCC
DDPMYTNIMMNIRLPRVVLAALVGAALSIAGAAFQGLLKNPLADPYTLGVSSGASVGAVV
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
TLFLGLHLPVIGGFTLPVLSVAAALATMAAVLFFSRLVHASMSVSTLILTGVITNSFLGA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FISLIIALTGDNLLPIVHWLLGSVSMRGWSYVILFLPFFLLGTILLIINGRELNVMTYGE
HHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECC
DKAKLLGVSVQQRKMMILIAGSLLTGSAVAVSGTIGFVGLVIPHITRLLWGTDHRHLLPL
CCHHHCCCCHHHCEEEEEEECCHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHH
SALLGAGFLVLADLLSRTIIEPIELPIGIITSLAGAPVFALILIRQHRGGRSL
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377