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The map label for this gene is yutK

Identifier: 16080271

GI number: 16080271

Start: 3307017

End: 3308231

Strand: Reverse

Name: yutK

Synonym: BSU32180

Alternate gene names: 16080271

Gene position: 3308231-3307017 (Counterclockwise)

Preceding gene: 16080272

Following gene: 16080270

Centisome position: 78.48

GC content: 47.0

Gene sequence:

>1215_bases
ATGAATGTTCTGTGGGGGCTGCTGGGCGCAGTTGCGATCATTGCTATCGCGTTTTTATTTTCAGAAAAGAAAAGCAATAT
TAAGATAAGAACCGTCATCGTTGGTTTATGCACACAGGTGGCGTTTGGATACATCGTGTTGAAATGGGAAGCGGGACGCG
CTGTTTTTTTATGGTTTTCAAGCCGTGTACAGCTTCTGATTGACTATGCGAATGAAGGCATCAGTTTTATTTTTGGACCG
CTTCTAAAGGTCGGAGACAGTCCGGCATTTGCATTAAGTGTACTGCCCGTTATCATTTTCTTCTCAGCACTGATTGCAGT
TTTATATCATTTGAAAATCATGCAGCTCGTTTTCCGTGTCATTGGCGGCGGATTGTCGAAGCTCCTTGGAACAAGCAAAA
CGGAATCTCTGGCGGCTGCTGCCAATATTTTTGTAGGACAATCAGAATCTCCGTTAGTGATCAAACCCCTGATTGCCGGG
CTGACGCGCTCTGAGTTGTTTACGATTATGACGAGCGGTCTATCGGCAGTTGCGGGATCTACCTTGTTTGGGTACGCGCT
TCTCGGTATTCCGATTGAGTACTTGCTGGCGGCCAGCTTTATGGCTGCTCCAGCTGGACTAGTCTTTGGTAAATTGATTA
TACCCGAAACGGAAAAAACGCAAACCGTAAAAAGCGATTTCAAAATGGATGAAGGCGAAGGCGCAGCCAATGTCATTGAC
GCAGCTGCAAAGGGAGCGTCAACAGGACTGCAAATTGCGTTAAATGTTGGGGCGATGCTGCTTGCGTTTGTTGCGTTAAT
CGCTGTAGTAAACGGTATTCTCGGCGGGGCTTTCGGCTTGTTCGGTTTAAAAGGCGTAACATTAGAATCCATTCTCGGCT
ATGTGTTTTCTCCTATCGCCTTTTTGATTGGCGTGCCTTGGCATGAAGCATTGCAGGCGGGAAGCTATATCGGCCAGAAA
TTGGTGCTGAATGAGTTTGTCGCTTATTCTAACTTCGGTTCGCACATCGGCGAGTTTTCTAAGAAAACTGCTACCATTAT
CAGTTTCGCGTTATGCGGATTCGCCAATTTTTCATCAATTGCGATTATGCTTGGTACGCTTGGCGGTTTAGCGCCCAGCC
GCCGTTCAGATATCGCACGTCTCGGCCTGAAGGCTGTTCTTGCAGGAACATTAGCCAATCTGCTCAGCGCAGCCATTGCC
GGCATGTTTATATAA

Upstream 100 bases:

>100_bases
GTACAAAAGAACTAAAAAAATGTGTAGACATCAAAAAATATTATTGTTATCGTATAAAAGATATTTTTTTAAATAAAATT
TAAGAGGTGTACGAGTATTC

Downstream 100 bases:

>100_bases
ACGATAAAAGCTCCTTGCGTCAGTGCAAGGAGCTTTTATGTATGAAAAACGGGGGATAATTGTATTGTGTCCGCTTATAA
TAGCTTTTATACTAAGAAAA

Product: Na+(H+)/nucleoside cotransporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNVLWGLLGAVAIIAIAFLFSEKKSNIKIRTVIVGLCTQVAFGYIVLKWEAGRAVFLWFSSRVQLLIDYANEGISFIFGP
LLKVGDSPAFALSVLPVIIFFSALIAVLYHLKIMQLVFRVIGGGLSKLLGTSKTESLAAAANIFVGQSESPLVIKPLIAG
LTRSELFTIMTSGLSAVAGSTLFGYALLGIPIEYLLAASFMAAPAGLVFGKLIIPETEKTQTVKSDFKMDEGEGAANVID
AAAKGASTGLQIALNVGAMLLAFVALIAVVNGILGGAFGLFGLKGVTLESILGYVFSPIAFLIGVPWHEALQAGSYIGQK
LVLNEFVAYSNFGSHIGEFSKKTATIISFALCGFANFSSIAIMLGTLGGLAPSRRSDIARLGLKAVLAGTLANLLSAAIA
GMFI

Sequences:

>Translated_404_residues
MNVLWGLLGAVAIIAIAFLFSEKKSNIKIRTVIVGLCTQVAFGYIVLKWEAGRAVFLWFSSRVQLLIDYANEGISFIFGP
LLKVGDSPAFALSVLPVIIFFSALIAVLYHLKIMQLVFRVIGGGLSKLLGTSKTESLAAAANIFVGQSESPLVIKPLIAG
LTRSELFTIMTSGLSAVAGSTLFGYALLGIPIEYLLAASFMAAPAGLVFGKLIIPETEKTQTVKSDFKMDEGEGAANVID
AAAKGASTGLQIALNVGAMLLAFVALIAVVNGILGGAFGLFGLKGVTLESILGYVFSPIAFLIGVPWHEALQAGSYIGQK
LVLNEFVAYSNFGSHIGEFSKKTATIISFALCGFANFSSIAIMLGTLGGLAPSRRSDIARLGLKAVLAGTLANLLSAAIA
GMFI
>Mature_404_residues
MNVLWGLLGAVAIIAIAFLFSEKKSNIKIRTVIVGLCTQVAFGYIVLKWEAGRAVFLWFSSRVQLLIDYANEGISFIFGP
LLKVGDSPAFALSVLPVIIFFSALIAVLYHLKIMQLVFRVIGGGLSKLLGTSKTESLAAAANIFVGQSESPLVIKPLIAG
LTRSELFTIMTSGLSAVAGSTLFGYALLGIPIEYLLAASFMAAPAGLVFGKLIIPETEKTQTVKSDFKMDEGEGAANVID
AAAKGASTGLQIALNVGAMLLAFVALIAVVNGILGGAFGLFGLKGVTLESILGYVFSPIAFLIGVPWHEALQAGSYIGQK
LVLNEFVAYSNFGSHIGEFSKKTATIISFALCGFANFSSIAIMLGTLGGLAPSRRSDIARLGLKAVLAGTLANLLSAAIA
GMFI

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family

Homologues:

Organism=Homo sapiens, GI11545853, Length=410, Percent_Identity=37.8048780487805, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI42542381, Length=414, Percent_Identity=37.43961352657, Blast_Score=271, Evalue=9e-73,
Organism=Homo sapiens, GI227116277, Length=414, Percent_Identity=36.231884057971, Blast_Score=258, Evalue=7e-69,
Organism=Escherichia coli, GI1788485, Length=414, Percent_Identity=47.1014492753623, Blast_Score=331, Evalue=5e-92,
Organism=Escherichia coli, GI1788488, Length=414, Percent_Identity=45.4106280193237, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI1788737, Length=394, Percent_Identity=34.7715736040609, Blast_Score=203, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17560276, Length=392, Percent_Identity=33.1632653061224, Blast_Score=220, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI71991794, Length=409, Percent_Identity=33.2518337408313, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI25146537, Length=213, Percent_Identity=34.7417840375587, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI45552519, Length=401, Percent_Identity=38.1546134663342, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI45552517, Length=401, Percent_Identity=38.1546134663342, Blast_Score=268, Evalue=7e-72,
Organism=Drosophila melanogaster, GI19921868, Length=401, Percent_Identity=38.1546134663342, Blast_Score=268, Evalue=7e-72,
Organism=Drosophila melanogaster, GI281360430, Length=401, Percent_Identity=39.1521197007481, Blast_Score=261, Evalue=6e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YUTK_BACSU (O32115)

Other databases:

- EMBL:   AL009126
- PIR:   E70024
- RefSeq:   NP_391098.1
- ProteinModelPortal:   O32115
- EnsemblBacteria:   EBBACT00000001439
- GeneID:   936517
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU32180
- NMPDR:   fig|224308.1.peg.3224
- GenoList:   BSU32180
- GeneTree:   EBGT00070000031902
- HOGENOM:   HBG713614
- OMA:   PRSFTIA
- PhylomeDB:   O32115
- ProtClustDB:   CLSK887826
- BioCyc:   BSUB:BSU32180-MONOMER
- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668
- PANTHER:   PTHR10590
- TIGRFAMs:   TIGR00804

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N

EC number: NA

Molecular weight: Translated: 42285; Mature: 42285

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11ccad28)-; HASH(0x11e14e40)-; HASH(0x123b4e0c)-; HASH(0x125a616c)-; HASH(0x1214c55c)-; HASH(0x10db92d4)-; HASH(0x11c91160)-; HASH(0xdd8f5e4)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLWGLLGAVAIIAIAFLFSEKKSNIKIRTVIVGLCTQVAFGYIVLKWEAGRAVFLWFS
CCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCEEEEEEECCCEEEEEEH
SRVQLLIDYANEGISFIFGPLLKVGDSPAFALSVLPVIIFFSALIAVLYHLKIMQLVFRV
HHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGGLSKLLGTSKTESLAAAANIFVGQSESPLVIKPLIAGLTRSELFTIMTSGLSAVAGS
HCCHHHHHHCCCCHHHHHHHHHHEECCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHH
TLFGYALLGIPIEYLLAASFMAAPAGLVFGKLIIPETEKTQTVKSDFKMDEGEGAANVID
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHH
AAAKGASTGLQIALNVGAMLLAFVALIAVVNGILGGAFGLFGLKGVTLESILGYVFSPIA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FLIGVPWHEALQAGSYIGQKLVLNEFVAYSNFGSHIGEFSKKTATIISFALCGFANFSSI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AIMLGTLGGLAPSRRSDIARLGLKAVLAGTLANLLSAAIAGMFI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNVLWGLLGAVAIIAIAFLFSEKKSNIKIRTVIVGLCTQVAFGYIVLKWEAGRAVFLWFS
CCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCEEEEEEECCCEEEEEEH
SRVQLLIDYANEGISFIFGPLLKVGDSPAFALSVLPVIIFFSALIAVLYHLKIMQLVFRV
HHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGGLSKLLGTSKTESLAAAANIFVGQSESPLVIKPLIAGLTRSELFTIMTSGLSAVAGS
HCCHHHHHHCCCCHHHHHHHHHHEECCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHH
TLFGYALLGIPIEYLLAASFMAAPAGLVFGKLIIPETEKTQTVKSDFKMDEGEGAANVID
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHH
AAAKGASTGLQIALNVGAMLLAFVALIAVVNGILGGAFGLFGLKGVTLESILGYVFSPIA
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FLIGVPWHEALQAGSYIGQKLVLNEFVAYSNFGSHIGEFSKKTATIISFALCGFANFSSI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AIMLGTLGGLAPSRRSDIARLGLKAVLAGTLANLLSAAIAGMFI
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377