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The map label for this gene is yubD

Identifier: 16080165

GI number: 16080165

Start: 3191843

End: 3193378

Strand: Reverse

Name: yubD

Synonym: BSU31130

Alternate gene names: 16080165

Gene position: 3193378-3191843 (Counterclockwise)

Preceding gene: 16080167

Following gene: 16080164

Centisome position: 75.75

GC content: 46.42

Gene sequence:

>1536_bases
ATGAAGACAAAACACTATTGGGTGATTTCTTTGCTCGCCGTCTTAGCGGTCGGGCCGGGATTGATGTCTAACACGGCATT
GTCGTCAGTTCAAGGCCTTGTTCAGAAAACGGTTGGAACAAGTGTCTTTACATCAGTAAATCCGATATTGATCGGCAATA
TGGCCTTTGCCTTGTTAGTTCCGGCAGGACCGCTGCTGAGGAAAAAATTCGGTGCTCGTCCCGTCTATCTGGCTTCATTA
CCTGTCTTTATACTAGGCTCACTGCTCATCGCATGTTCAGGCGATATTGCATTGATGGCGGCAGGGCGCTTTTTACAAGG
GGCGGCAACAGGCGTCATGCTGATGATTATGATTCCAATGCTTGTACTGTCATTCCCGATTGAACGCAGGAACTATGCAC
TGCTTGTGCTGATCGGGGGATTCTATGGTTCTGTTATCATCGGTACAATCCTGGGAACCATTGCAACAAGCTGCGGGCAT
TGGAGATGGCTGTTTTTCATCTTTGGCACCTTGTCCCTGATCGGTGTCGCGGTGAGCTATTTCTTTCTTCATGATGAGCA
TCACGGAGCGGCGGATCAAGAACAGCCGCTTGATCGTGCGGGAATTCTTTTATCTGTCTTCCTTGCCGCAGCCTCAGCGG
TTTCATTCATTTTTCTGCAAAAATGGGGGCTGTCATCGGGTTATGTATGGATTGGTTTCGGGGTGACGTTATGTTTGCTC
ATTGGTCTATTGATTGTGGAATATAAAGTGAAAAACCCCTTCATATCTATTAAACTGATGCTGCTGCCAAAACCGGTGCT
CGGCTTATTGATCATAGCTGCAGGGACGATAACGGTAGCTGTCAGCCTTTCTGCTTTTCAAGGCTTGCTCCGTCAAATGT
ATGATATTTCTCAGGAGCATCTCATTCTTTTAAGCTTGACTCTTTTAATCGGAGTGGCGATCGCGGCCATTTTGAGCGCT
CTGTTATACGATAAAGTCGGACCAGGGATGCTCGGTATTATCGGCGGACTCATTCTCGTTTTTGTGAATTTTCAATGGCT
GCATATACAGGATCGATCATCTCTTTATATGTTCGCGGCACTGTTTATCATGCTTGCAGCGGGAACAGGCCTGACAGTCG
CCGCAGGGCTGATGGGAGCTGCCATGGGAGGCCCGCTGCCTGATTTGGTCAAGAGAATGACAGCTGTTCAGTTTTTAAGA
TTGTTTGTCTATATGGGAGTTCCCATTCTCATCGGCTTTTTCACGAAAAAAGATGCTGCCAGACAAAGCGGTTCGGTACA
GGATTCTATGATGACTGCTTATCATGATCTCTTCTTCATTTCTTTTATCCTTAGCGTGCTGCTCGTCTGCCTGTCATTTT
GTATGAATGCCACTGGAATGGGGCACAAGCTGGCACATAAACCACATGATAAAGCGAAAACAGCTCCGGAAAAACCGGCC
GTCTCAGCACAAGGTTTGTCGAAGGCAACTGTCAAATCATATAAAGTAATAAATGATACGGAATATCGGAATGCACTCAG
AAATTTACAAAAATAG

Upstream 100 bases:

>100_bases
ATATTAGAATGAAAGCTAATGGTATGCAAAATCTATTAGCTTCTTTTGTTTTCAAAAAATGATGTGTTTCGCATGTATTC
ATATAGGAAGGGATGACAAC

Downstream 100 bases:

>100_bases
AAACATGGTAAAAACCTTTTCATTGAGCGAAAAGGTTTTTATTTTGCAATCTTTTCCCAACTTTATCCCTAAAGAATTGA
AAAATATTAGAAGTGCAAGT

Product: efflux transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MKTKHYWVISLLAVLAVGPGLMSNTALSSVQGLVQKTVGTSVFTSVNPILIGNMAFALLVPAGPLLRKKFGARPVYLASL
PVFILGSLLIACSGDIALMAAGRFLQGAATGVMLMIMIPMLVLSFPIERRNYALLVLIGGFYGSVIIGTILGTIATSCGH
WRWLFFIFGTLSLIGVAVSYFFLHDEHHGAADQEQPLDRAGILLSVFLAAASAVSFIFLQKWGLSSGYVWIGFGVTLCLL
IGLLIVEYKVKNPFISIKLMLLPKPVLGLLIIAAGTITVAVSLSAFQGLLRQMYDISQEHLILLSLTLLIGVAIAAILSA
LLYDKVGPGMLGIIGGLILVFVNFQWLHIQDRSSLYMFAALFIMLAAGTGLTVAAGLMGAAMGGPLPDLVKRMTAVQFLR
LFVYMGVPILIGFFTKKDAARQSGSVQDSMMTAYHDLFFISFILSVLLVCLSFCMNATGMGHKLAHKPHDKAKTAPEKPA
VSAQGLSKATVKSYKVINDTEYRNALRNLQK

Sequences:

>Translated_511_residues
MKTKHYWVISLLAVLAVGPGLMSNTALSSVQGLVQKTVGTSVFTSVNPILIGNMAFALLVPAGPLLRKKFGARPVYLASL
PVFILGSLLIACSGDIALMAAGRFLQGAATGVMLMIMIPMLVLSFPIERRNYALLVLIGGFYGSVIIGTILGTIATSCGH
WRWLFFIFGTLSLIGVAVSYFFLHDEHHGAADQEQPLDRAGILLSVFLAAASAVSFIFLQKWGLSSGYVWIGFGVTLCLL
IGLLIVEYKVKNPFISIKLMLLPKPVLGLLIIAAGTITVAVSLSAFQGLLRQMYDISQEHLILLSLTLLIGVAIAAILSA
LLYDKVGPGMLGIIGGLILVFVNFQWLHIQDRSSLYMFAALFIMLAAGTGLTVAAGLMGAAMGGPLPDLVKRMTAVQFLR
LFVYMGVPILIGFFTKKDAARQSGSVQDSMMTAYHDLFFISFILSVLLVCLSFCMNATGMGHKLAHKPHDKAKTAPEKPA
VSAQGLSKATVKSYKVINDTEYRNALRNLQK
>Mature_511_residues
MKTKHYWVISLLAVLAVGPGLMSNTALSSVQGLVQKTVGTSVFTSVNPILIGNMAFALLVPAGPLLRKKFGARPVYLASL
PVFILGSLLIACSGDIALMAAGRFLQGAATGVMLMIMIPMLVLSFPIERRNYALLVLIGGFYGSVIIGTILGTIATSCGH
WRWLFFIFGTLSLIGVAVSYFFLHDEHHGAADQEQPLDRAGILLSVFLAAASAVSFIFLQKWGLSSGYVWIGFGVTLCLL
IGLLIVEYKVKNPFISIKLMLLPKPVLGLLIIAAGTITVAVSLSAFQGLLRQMYDISQEHLILLSLTLLIGVAIAAILSA
LLYDKVGPGMLGIIGGLILVFVNFQWLHIQDRSSLYMFAALFIMLAAGTGLTVAAGLMGAAMGGPLPDLVKRMTAVQFLR
LFVYMGVPILIGFFTKKDAARQSGSVQDSMMTAYHDLFFISFILSVLLVCLSFCMNATGMGHKLAHKPHDKAKTAPEKPA
VSAQGLSKATVKSYKVINDTEYRNALRNLQK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YUBD_BACSU (O32084)

Other databases:

- EMBL:   AL009126
- EMBL:   U87792
- PIR:   G70006
- RefSeq:   NP_390991.1
- ProteinModelPortal:   O32084
- EnsemblBacteria:   EBBACT00000000390
- GeneID:   938834
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31130
- NMPDR:   fig|224308.1.peg.3116
- GenoList:   BSU31130
- GeneTree:   EBGT00050000000119
- HOGENOM:   HBG337939
- OMA:   GKGRRIT
- ProtClustDB:   CLSK887782
- BioCyc:   BSUB:BSU31130-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 54951; Mature: 54951

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x119d9fe0)-; HASH(0x11daaa24)-; HASH(0x1182535c)-; HASH(0x1195b978)-; HASH(0x100c6db8)-; HASH(0x11de8ed8)-; HASH(0x10876f28)-; HASH(0x11172b18)-; HASH(0x115ed968)-; HASH(0x116b07bc)-; HASH(0x11d17758)-; HASH(0x11e35e7c)-; HASH(0x11ea46a4)-; HASH(0x117c3870)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKHYWVISLLAVLAVGPGLMSNTALSSVQGLVQKTVGTSVFTSVNPILIGNMAFALLV
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEHHHHHHHHH
PAGPLLRKKFGARPVYLASLPVFILGSLLIACSGDIALMAAGRFLQGAATGVMLMIMIPM
CCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVLSFPIERRNYALLVLIGGFYGSVIIGTILGTIATSCGHWRWLFFIFGTLSLIGVAVSY
HHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FFLHDEHHGAADQEQPLDRAGILLSVFLAAASAVSFIFLQKWGLSSGYVWIGFGVTLCLL
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
IGLLIVEYKVKNPFISIKLMLLPKPVLGLLIIAAGTITVAVSLSAFQGLLRQMYDISQEH
HHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LILLSLTLLIGVAIAAILSALLYDKVGPGMLGIIGGLILVFVNFQWLHIQDRSSLYMFAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHH
LFIMLAAGTGLTVAAGLMGAAMGGPLPDLVKRMTAVQFLRLFVYMGVPILIGFFTKKDAA
HHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQSGSVQDSMMTAYHDLFFISFILSVLLVCLSFCMNATGMGHKLAHKPHDKAKTAPEKPA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCC
VSAQGLSKATVKSYKVINDTEYRNALRNLQK
CCCCCCHHHHHHHHHCCCCHHHHHHHHHCCH
>Mature Secondary Structure
MKTKHYWVISLLAVLAVGPGLMSNTALSSVQGLVQKTVGTSVFTSVNPILIGNMAFALLV
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEHHHHHHHHH
PAGPLLRKKFGARPVYLASLPVFILGSLLIACSGDIALMAAGRFLQGAATGVMLMIMIPM
CCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVLSFPIERRNYALLVLIGGFYGSVIIGTILGTIATSCGHWRWLFFIFGTLSLIGVAVSY
HHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FFLHDEHHGAADQEQPLDRAGILLSVFLAAASAVSFIFLQKWGLSSGYVWIGFGVTLCLL
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
IGLLIVEYKVKNPFISIKLMLLPKPVLGLLIIAAGTITVAVSLSAFQGLLRQMYDISQEH
HHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LILLSLTLLIGVAIAAILSALLYDKVGPGMLGIIGGLILVFVNFQWLHIQDRSSLYMFAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHH
LFIMLAAGTGLTVAAGLMGAAMGGPLPDLVKRMTAVQFLRLFVYMGVPILIGFFTKKDAA
HHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQSGSVQDSMMTAYHDLFFISFILSVLLVCLSFCMNATGMGHKLAHKPHDKAKTAPEKPA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCC
VSAQGLSKATVKSYKVINDTEYRNALRNLQK
CCCCCCHHHHHHHHHCCCCHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377