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The map label for this gene is hisJ

Identifier: 16080014

GI number: 16080014

Start: 3031614

End: 3032420

Strand: Direct

Name: hisJ

Synonym: BSU29620

Alternate gene names: 16080014

Gene position: 3031614-3032420 (Clockwise)

Preceding gene: 16080012

Following gene: 255767680

Centisome position: 71.91

GC content: 44.61

Gene sequence:

>807_bases
ATGCAAAAGCGAGACGGACATATTCACACACCATTTTGCCCTCACGGCTCCAATGACACACTCAGACAATATGCAGAAGA
AGCCTTAAAAAAAGGGTTCGAATCGATTACTTTTACCGAACACGCCCCATTGCCGCCATCTTTTACCGATCCCACGCCGC
TGAAAGACAGCGCGATGGCGCAAGCTTCTTTGGAACGCTATATTCATGAAATTTCCGGATTAAAAAAAGAATATCGCGGA
CAGCTTAGCATACGGACAGGGCTTGAAGTCGATTATATCGCTGAATTTGAAGACGAAATTACATTATTCCTAGACACATA
CGGGCCATATTTAGATGACAGCATCTTATCCGTTCATTTTTTGCGCACAGACTCTTCCTATCTATGCCTTGATTATGACG
AGCATACCTTCAAAGAGCTGATTTCAGCCTGCGGAAGCATTGAAGCGGTATATGAACAATATTACCGGAGTATCTATTCT
TCCATTGTAGCATCTCTCGGCGTTTATAAGCCAAAAAGAGTCGGTCACATCACACTCGTCCAAAAATTCATCAAGCTGTT
TCCATACAGCATGTCAGAGCATATTCGCGGCCTCGTTTCTCTGTGCCTGAATGCCATTGAAGAAAACGGAATGGAGCTCG
ACTTCAATACTTCCGGCTTAAGAAAAACTTACGCTGGCGGTATTTATATCGAGGATTGGATGCTGAATGAAGCGAAGCAA
AAGAAGATCCCGCTTGTGTTTGGGTCTGATGCCCATCAAGCGGGAGATGTCGGATATGCGTATGAGGCGTTTTTGGAACG
GTGCTAG

Upstream 100 bases:

>100_bases
GTTATTATGATACCATGTAACAAACATTTTTTGACCAGAAATCAAAAACTTTTTGTGCAAAATCGGCAGGATTTGACTAT
TTTTTCATGGGGTGACATCA

Downstream 100 bases:

>100_bases
TTGGTGAGCGCCACGTCTCCTGTCCGGAAGACGCTTCTGATCCAAATCTTGATTTCTTCAAAATACATTTTATAAAAATA
CGGCTCGTGCGGCTGCATGT

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MQKRDGHIHTPFCPHGSNDTLRQYAEEALKKGFESITFTEHAPLPPSFTDPTPLKDSAMAQASLERYIHEISGLKKEYRG
QLSIRTGLEVDYIAEFEDEITLFLDTYGPYLDDSILSVHFLRTDSSYLCLDYDEHTFKELISACGSIEAVYEQYYRSIYS
SIVASLGVYKPKRVGHITLVQKFIKLFPYSMSEHIRGLVSLCLNAIEENGMELDFNTSGLRKTYAGGIYIEDWMLNEAKQ
KKIPLVFGSDAHQAGDVGYAYEAFLERC

Sequences:

>Translated_268_residues
MQKRDGHIHTPFCPHGSNDTLRQYAEEALKKGFESITFTEHAPLPPSFTDPTPLKDSAMAQASLERYIHEISGLKKEYRG
QLSIRTGLEVDYIAEFEDEITLFLDTYGPYLDDSILSVHFLRTDSSYLCLDYDEHTFKELISACGSIEAVYEQYYRSIYS
SIVASLGVYKPKRVGHITLVQKFIKLFPYSMSEHIRGLVSLCLNAIEENGMELDFNTSGLRKTYAGGIYIEDWMLNEAKQ
KKIPLVFGSDAHQAGDVGYAYEAFLERC
>Mature_268_residues
MQKRDGHIHTPFCPHGSNDTLRQYAEEALKKGFESITFTEHAPLPPSFTDPTPLKDSAMAQASLERYIHEISGLKKEYRG
QLSIRTGLEVDYIAEFEDEITLFLDTYGPYLDDSILSVHFLRTDSSYLCLDYDEHTFKELISACGSIEAVYEQYYRSIYS
SIVASLGVYKPKRVGHITLVQKFIKLFPYSMSEHIRGLVSLCLNAIEENGMELDFNTSGLRKTYAGGIYIEDWMLNEAKQ
KKIPLVFGSDAHQAGDVGYAYEAFLERC

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS9_BACSU (O34411)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   D70002
- RefSeq:   NP_390840.1
- ProteinModelPortal:   O34411
- SMR:   O34411
- EnsemblBacteria:   EBBACT00000003689
- GeneID:   937924
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU29620
- NMPDR:   fig|224308.1.peg.2965
- GenoList:   BSU29620
- GeneTree:   EBGT00050000002062
- HOGENOM:   HBG314019
- OMA:   FTEHAPL
- ProtClustDB:   PRK08123
- BioCyc:   BSUB:BSU29620-MONOMER
- BRENDA:   3.1.3.15
- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195
- PANTHER:   PTHR21039
- TIGRFAMs:   TIGR01856

Pfam domain/function: PF02811 PHP; SSF89550 PHP-like

EC number: =3.1.3.15

Molecular weight: Translated: 30477; Mature: 30477

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRDGHIHTPFCPHGSNDTLRQYAEEALKKGFESITFTEHAPLPPSFTDPTPLKDSAMA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHH
QASLERYIHEISGLKKEYRGQLSIRTGLEVDYIAEFEDEITLFLDTYGPYLDDSILSVHF
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCEEEEEECCCCCCCCHHHEEEE
LRTDSSYLCLDYDEHTFKELISACGSIEAVYEQYYRSIYSSIVASLGVYKPKRVGHITLV
EECCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
QKFIKLFPYSMSEHIRGLVSLCLNAIEENGMELDFNTSGLRKTYAGGIYIEDWMLNEAKQ
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCEEEEHHHHCHHHH
KKIPLVFGSDAHQAGDVGYAYEAFLERC
CCCCEEECCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQKRDGHIHTPFCPHGSNDTLRQYAEEALKKGFESITFTEHAPLPPSFTDPTPLKDSAMA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHH
QASLERYIHEISGLKKEYRGQLSIRTGLEVDYIAEFEDEITLFLDTYGPYLDDSILSVHF
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCEEEEEECCCCCCCCHHHEEEE
LRTDSSYLCLDYDEHTFKELISACGSIEAVYEQYYRSIYSSIVASLGVYKPKRVGHITLV
EECCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
QKFIKLFPYSMSEHIRGLVSLCLNAIEENGMELDFNTSGLRKTYAGGIYIEDWMLNEAKQ
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCEEEEHHHHCHHHH
KKIPLVFGSDAHQAGDVGYAYEAFLERC
CCCCEEECCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10322033