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The map label for this gene is moaB

Identifier: 16079998

GI number: 16079998

Start: 3014514

End: 3015026

Strand: Reverse

Name: moaB

Synonym: BSU29460

Alternate gene names: 16079998

Gene position: 3015026-3014514 (Counterclockwise)

Preceding gene: 16079999

Following gene: 16079997

Centisome position: 71.52

GC content: 47.37

Gene sequence:

>513_bases
ATGAGCGTTCAAGAGCATAAACAAGAAGCTCCCGATATCGTTCGGTGCAAAGTGATTACTGTCAGTGACACGAGGACAGA
TGAAACCGATAAAAGCGGCAAGCTGATGATCTCATTTTTAGAAGAAGCCGGTCATCATATTGCCGCATATGAAATTGTAA
AAGACGAAAAGGATGCTTTGCAACGGTCAGTGCTTGCGGGCTGCATGGATGAACAGACAGACGCGGTACTCTTAAACGGA
GGGACAGGCATAGCAGATCGGGATGTCACAATTGAAGCCATAACGCCGCTGTTTTCGAAAGAACTGCCCGGCTTTGGAGA
AATATTCAGGATGCTGAGTTATACAGAGGATATCGGCTCTGCCGCAATCATGTCGAGAGCAACTGCCGGCGTCATTCAGC
ATACCGCTGTTTTCTCAACGCCAGGCTCAAGCGGCGCAGTAAAGCTGGCAATGAATAAGCTGATTATTCCCGAACTTGCG
CATGTGGTCAGAGAAATCAGAAAAGACAAGTAA

Upstream 100 bases:

>100_bases
TCGTTTAGCAAAATAAATCGCATGAAAGCACATTCTCTTGAATGTGCTTTTTTGTTGATGCATGATAGTGACAGACAGAA
AACATAAAAGAGGTGGGCCA

Downstream 100 bases:

>100_bases
ATGAATAAATACTATGAAACTTCACCTGAAATTTAGGTGAAGTTTTTTTTATAAAAGGCTTGAAAAAACGAAACGTACTT
GTTAAAGTGTATACATACAA

Product: molybdopterin GTP-binding precursor Z biosynthesis component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSVQEHKQEAPDIVRCKVITVSDTRTDETDKSGKLMISFLEEAGHHIAAYEIVKDEKDALQRSVLAGCMDEQTDAVLLNG
GTGIADRDVTIEAITPLFSKELPGFGEIFRMLSYTEDIGSAAIMSRATAGVIQHTAVFSTPGSSGAVKLAMNKLIIPELA
HVVREIRKDK

Sequences:

>Translated_170_residues
MSVQEHKQEAPDIVRCKVITVSDTRTDETDKSGKLMISFLEEAGHHIAAYEIVKDEKDALQRSVLAGCMDEQTDAVLLNG
GTGIADRDVTIEAITPLFSKELPGFGEIFRMLSYTEDIGSAAIMSRATAGVIQHTAVFSTPGSSGAVKLAMNKLIIPELA
HVVREIRKDK
>Mature_169_residues
SVQEHKQEAPDIVRCKVITVSDTRTDETDKSGKLMISFLEEAGHHIAAYEIVKDEKDALQRSVLAGCMDEQTDAVLLNGG
TGIADRDVTIEAITPLFSKELPGFGEIFRMLSYTEDIGSAAIMSRATAGVIQHTAVFSTPGSSGAVKLAMNKLIIPELAH
VVREIRKDK

Specific function: Maybe involved in the biosynthesis of molybdopterin

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family

Homologues:

Organism=Homo sapiens, GI10880983, Length=159, Percent_Identity=30.188679245283, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI66932975, Length=159, Percent_Identity=30.188679245283, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787000, Length=145, Percent_Identity=42.0689655172414, Blast_Score=123, Evalue=7e-30,
Organism=Drosophila melanogaster, GI17136978, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24638841, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAB_BACSU (O34457)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   H69658
- RefSeq:   NP_390824.1
- ProteinModelPortal:   O34457
- SMR:   O34457
- EnsemblBacteria:   EBBACT00000000533
- GeneID:   937349
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU29460
- NMPDR:   fig|224308.1.peg.2949
- GenoList:   BSU29460
- GeneTree:   EBGT00050000002994
- HOGENOM:   HBG460560
- OMA:   IGTATIQ
- PhylomeDB:   O34457
- ProtClustDB:   CLSK2752478
- BioCyc:   BSUB:BSU29460-MONOMER
- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006443
- SMART:   SM00852
- TIGRFAMs:   TIGR00177

Pfam domain/function: PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 18457; Mature: 18326

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQEHKQEAPDIVRCKVITVSDTRTDETDKSGKLMISFLEEAGHHIAAYEIVKDEKDAL
CCCHHHHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHCHHHHH
QRSVLAGCMDEQTDAVLLNGGTGIADRDVTIEAITPLFSKELPGFGEIFRMLSYTEDIGS
HHHHHHHHCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAIMSRATAGVIQHTAVFSTPGSSGAVKLAMNKLIIPELAHVVREIRKDK
HHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVQEHKQEAPDIVRCKVITVSDTRTDETDKSGKLMISFLEEAGHHIAAYEIVKDEKDAL
CCHHHHHCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHCHHHHH
QRSVLAGCMDEQTDAVLLNGGTGIADRDVTIEAITPLFSKELPGFGEIFRMLSYTEDIGS
HHHHHHHHCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AAIMSRATAGVIQHTAVFSTPGSSGAVKLAMNKLIIPELAHVVREIRKDK
HHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377