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The map label for this gene is ysnA

Identifier: 16079888

GI number: 16079888

Start: 2900545

End: 2901141

Strand: Reverse

Name: ysnA

Synonym: BSU28360

Alternate gene names: 16079888

Gene position: 2901141-2900545 (Counterclockwise)

Preceding gene: 16079889

Following gene: 255767653

Centisome position: 68.82

GC content: 43.72

Gene sequence:

>597_bases
TTGATCATCATGAAAGAAGCAATTATTGCAACACATAATCCGGGAAAAGTGAAGGAATTCAAAGAAATTCTTGAGCCAAG
AGGCTATGATGTCAAATCTTTAGCTGAAATTGGATTCACAGAGGAAATTGAAGAAACAGGCCATACATTTGAAGAAAATG
CCATTATGAAAGCGGAAGCTGTTGCCAAAGCAGTGAACAAAATGGTGATTGCGGATGACTCCGGACTATCCATCGATAAT
CTTGGCGGCAGACCCGGGGTTTATTCAGCCCGCTATGCAGGGGAACAGAAAGACGACCAGGCAAATATCGAAAAAGTGCT
CAGCGAGCTGAAAGGTATCGAAAAAGAACAGCGCACCGCCCGTTTCCGCTGCGCACTGGCCGTGAGTATTCCCGGAGAGG
AAACAAAAACAGTCGAAGGCCATGTTGAAGGGTATATTGCTGAAGAACCGAGAGGAGAATATGGCTTTGGCTATGACCCA
ATTTTTATCGTGAAAGATAAAGATAAGACGATGGCTGAACTGACAAGTGATGAAAAAAATAAAATCAGCCATAGGGCTGA
CGCGCTTAAAAAGCTGTCTAAGCTTTTGGAGGCATAA

Upstream 100 bases:

>100_bases
TCTTCTGGGTCTTGCGGAAAAAGGAATCCAAGAGCTGATTGACAAGCAAAAAGAAGTGCTGGGTGATTCTCTGCCAGAAC
TGAAATAAAGACAGAAAGGC

Downstream 100 bases:

>100_bases
GGAGGAAGCTTGTACATGAACGTGCTGATTATCAGTGACAGCCATGGGCTTGAAGAAGAACTCCAAACCATTGCGAAACG
GCATGAGGCAGAAGTTGATC

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIIMKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGHTFEENAIMKAEAVAKAVNKMVIADDSGLSIDN
LGGRPGVYSARYAGEQKDDQANIEKVLSELKGIEKEQRTARFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDP
IFIVKDKDKTMAELTSDEKNKISHRADALKKLSKLLEA

Sequences:

>Translated_198_residues
MIIMKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGHTFEENAIMKAEAVAKAVNKMVIADDSGLSIDN
LGGRPGVYSARYAGEQKDDQANIEKVLSELKGIEKEQRTARFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDP
IFIVKDKDKTMAELTSDEKNKISHRADALKKLSKLLEA
>Mature_198_residues
MIIMKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGHTFEENAIMKAEAVAKAVNKMVIADDSGLSIDN
LGGRPGVYSARYAGEQKDDQANIEKVLSELKGIEKEQRTARFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDP
IFIVKDKDKTMAELTSDEKNKISHRADALKKLSKLLEA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=191, Percent_Identity=28.2722513089005, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI31657144, Length=142, Percent_Identity=31.6901408450704, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789324, Length=191, Percent_Identity=47.6439790575916, Blast_Score=172, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19920712, Length=196, Percent_Identity=31.6326530612245, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_BACSU (P94558)

Other databases:

- EMBL:   Z75208
- EMBL:   AL009126
- PIR:   C69986
- RefSeq:   NP_390714.1
- ProteinModelPortal:   P94558
- SMR:   P94558
- EnsemblBacteria:   EBBACT00000002345
- GeneID:   937465
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28360
- NMPDR:   fig|224308.1.peg.2839
- GenoList:   BSU28360
- GeneTree:   EBGT00050000001334
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- PhylomeDB:   P94558
- ProtClustDB:   PRK14822
- BioCyc:   BSUB:BSU28360-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21933; Mature: 21933

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIMKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGHTFEENAIMKAEA
CEEECCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHH
VAKAVNKMVIADDSGLSIDNLGGRPGVYSARYAGEQKDDQANIEKVLSELKGIEKEQRTA
HHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
RFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDPIFIVKDKDKTMAELTSDEKN
HEEEEEEEECCCCCCCEEEHHHCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHCCHHH
KISHRADALKKLSKLLEA
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIIMKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGHTFEENAIMKAEA
CEEECCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHHHHH
VAKAVNKMVIADDSGLSIDNLGGRPGVYSARYAGEQKDDQANIEKVLSELKGIEKEQRTA
HHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHH
RFRCALAVSIPGEETKTVEGHVEGYIAEEPRGEYGFGYDPIFIVKDKDKTMAELTSDEKN
HEEEEEEEECCCCCCCEEEHHHCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHCCHHH
KISHRADALKKLSKLLEA
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377; 1624460